ES2001625A6 - Un procedimiento para preparar oxadiazoles, tiadiazoles, triazoles, oxadiazinas,tiadiazinas y triazinas. - Google Patents

Un procedimiento para preparar oxadiazoles, tiadiazoles, triazoles, oxadiazinas,tiadiazinas y triazinas.

Info

Publication number
ES2001625A6
ES2001625A6 ES8601508A ES8601508A ES2001625A6 ES 2001625 A6 ES2001625 A6 ES 2001625A6 ES 8601508 A ES8601508 A ES 8601508A ES 8601508 A ES8601508 A ES 8601508A ES 2001625 A6 ES2001625 A6 ES 2001625A6
Authority
ES
Spain
Prior art keywords
soln
stirred
cpds
thiadiazole
oxadiazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8601508A
Other languages
English (en)
Inventor
Roger Charles Brown
David Hulme Robinson
John Dixon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Ltd
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858521697A external-priority patent/GB8521697D0/en
Priority claimed from GB858524932A external-priority patent/GB8524932D0/en
Priority claimed from GB858530143A external-priority patent/GB8530143D0/en
Priority claimed from GB868609793A external-priority patent/GB8609793D0/en
Priority claimed from EP86306325A external-priority patent/EP0217519B1/en
Application filed by Fisons Ltd filed Critical Fisons Ltd
Priority claimed from SU874202059A external-priority patent/RU1804458C/ru
Publication of ES2001625A6 publication Critical patent/ES2001625A6/es
Expired legal-status Critical Current

Links

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  • Peptides Or Proteins (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE DESCRIBE UN PROCEDIMIENTO PARA PREPARAR OXADIAZOLES, TIADIAZOLES, TRIAZOLES, OXIDIAZINAS, TIADIAZINAS Y TRIAZINAS DE FORMULA: DONDE Y ES S, O O UN RADICAL ORGANICO, N ES 0 O 1, R3 ES HIDROGENO O UN RADICAL ORGANICO, R ES HIDROGENO O ALQUILO Y Z ES R2CH(COOH)NH- O R1SCH2-, SIENDO R1 HIDROGENO O ACILO Y R2 ALQUILO O FENILALQUILO, EN CUYO PROCEDIMIENTO SE ELIMINA UN GRUPO PROTECTOR DE UN COMPUESTO DE FORMULA I EN QUE UNO O MAS DE LOS GRUPOS AMINO O ACIDO CARBOXILICO ESTAN PROTEGIDOS, MEDIANTE HIDROLISIS BASICA O ACIDA O MEDIANTE HIDROGENACION UTILIZANDO UN CATALIZADOR DE METAL DE TRANSICION. LOS COMPUESTOS DE FORMULA I, ASI COMO SUS SALES, ESTERES O AMIDAS, PUEDEN OBTENERSE SIGUIENDO OTRAS VIAS DE SINTESIS QUE SE DESCRIBEN EN LA MEMORIA. LOS COMPUESTOS OBTENIDOS SON ESPECIALMENTE UTILES COMO AGENTES ANTIHIPERTENSORES.
ES8601508A 1985-08-31 1986-08-29 Un procedimiento para preparar oxadiazoles, tiadiazoles, triazoles, oxadiazinas,tiadiazinas y triazinas. Expired ES2001625A6 (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB858521697A GB8521697D0 (en) 1985-08-31 1985-08-31 Nitrogen & sulphur heterocycles
GB858524932A GB8524932D0 (en) 1985-10-09 1985-10-09 Nitrogen & sulphur heterocycles
GB858530143A GB8530143D0 (en) 1985-12-06 1985-12-06 Nitrogen
GB868609793A GB8609793D0 (en) 1986-04-22 1986-04-22 Nitrogen containing heterocycles
EP86306325A EP0217519B1 (en) 1985-08-31 1986-08-15 5-membered heterocyclic ring angiotensin converting enzyme inhibitors
SU874202059A RU1804458C (ru) 1985-08-31 1987-02-09 Способ получени производных 1,3,4-тиадиазол-2-карбоновых кислот или их фармацевтически приемлемых солей, сложных эфиров или амидов

Publications (1)

Publication Number Publication Date
ES2001625A6 true ES2001625A6 (es) 1988-06-01

Family

ID=27545392

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8601508A Expired ES2001625A6 (es) 1985-08-31 1986-08-29 Un procedimiento para preparar oxadiazoles, tiadiazoles, triazoles, oxadiazinas,tiadiazinas y triazinas.

Country Status (1)

Country Link
ES (1) ES2001625A6 (es)

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20001204