EP4346456A1 - Aerosol generating composition comprising nicotine and acid or nicotine salt - Google Patents

Aerosol generating composition comprising nicotine and acid or nicotine salt

Info

Publication number
EP4346456A1
EP4346456A1 EP22731405.1A EP22731405A EP4346456A1 EP 4346456 A1 EP4346456 A1 EP 4346456A1 EP 22731405 A EP22731405 A EP 22731405A EP 4346456 A1 EP4346456 A1 EP 4346456A1
Authority
EP
European Patent Office
Prior art keywords
aerosol
generating
generating material
generating composition
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP22731405.1A
Other languages
German (de)
English (en)
French (fr)
Inventor
John Ulrich
Jennifer Rowe
Michael F. Davis
JR. John Will CARAWAY
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RAI Strategic Holdings Inc
Original Assignee
RAI Strategic Holdings Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RAI Strategic Holdings Inc filed Critical RAI Strategic Holdings Inc
Publication of EP4346456A1 publication Critical patent/EP4346456A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
    • A24B15/241—Extraction of specific substances
    • A24B15/243—Nicotine
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/281—Treatment of tobacco products or tobacco substitutes by chemical substances the action of the chemical substances being delayed
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/301—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by aromatic compounds
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/42—Treatment of tobacco products or tobacco substitutes by chemical substances by organic and inorganic substances
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40—Constructional details, e.g. connection of cartridges and battery parts

Definitions

  • the present invention relates to aerosol-generating compositions comprising an aerosol-generating material; consumables for use within a non-combustible aerosol provision system, the consumables comprising the aerosol-generating composition; and non-combustible aerosol provision systems.
  • Smoking articles such as cigarettes, cigars and the like burn tobacco during use to create tobacco smoke.
  • Alternatives to these types of articles release an inhalable aerosol or vapour by releasing compounds from a substrate material by heating without burning.
  • These may be referred to as non-combustible smoking articles, aerosol generating assemblies or non-combustible aerosol provision systems.
  • a heating device which release compounds by heating, but not burning, a solid aerosolisable material.
  • This solid aerosolisable material may, in some cases, contain a tobacco material.
  • the heating volatilises at least one component of the material, typically forming an inhalable aerosol.
  • These products may be referred to as heat-not-bum devices, tobacco heating devices or tobacco heating products (THP).
  • THP tobacco heating products
  • e-cigarette / tobacco heating product hybrid devices also known as electronic tobacco hybrid devices.
  • These hybrid devices contain a liquid source (which may or may not contain nicotine) which is vaporised by heating to produce an inhalable vapour or aerosol.
  • the device additionally contains a solid aerosolisable material (which may or may not contain a tobacco material) and components of this material are entrained in the inhalable vapour or aerosol to produce the inhaled medium.
  • an aerosol-generating composition comprising an aerosol-generating material, wherein the aerosol-generating material comprises: about 1 to about 30 wt% nicotine; about 15 to about 80 wt% gelling agent; about 10 to about 60 wt% aerosol-former material; about 1 to about 30 wt% acid; and - optionally filler, wherein the wt% values are calculated on a dry weight basis; and wherein the molar ratio of nicotine to acid is 2.2:1 or less.
  • an aerosol-generating composition comprising an aerosol-generating material, wherein the aerosol-generating material comprises: about 5 to about 30 wt% nicotine salt; about 15 to about 80 wt% gelling agent; about 10 to about 60 wt% aerosol-former material; and optionally filler, wherein the wt% values are calculated on a dry weight basis.
  • an aerosol-generating composition comprising an aerosol-generating material, wherein the aerosol-generating material comprises: about 1 to about 30 wt% nicotine salt; - about 45 to about 80 wt% gelling agent; about 10 to about 54 wt% aerosol-former material; and optionally filler, wherein the wt% values are calculated on a dry weight basis.
  • a consumable for use within a non-combustible aerosol provision system comprising the aerosol-generating composition as defined herein.
  • a non-combustible aerosol provision system comprising the consumable as defined herein and a non-combustible aerosol provision device, the non-combustible aerosol provision device comprising an aerosol-generation device arranged to generate aerosol from the consumable when the consumable is used with the non-combustible aerosol provision device.
  • Figure 1 shows a section view of an example of a consumable.
  • Figure 2 shows a perspective view of the article of Figure 1.
  • Figure 3 shows a sectional elevation of an example of a consumable.
  • Figure 4 shows a perspective view of the article of Figure 3.
  • Figure 5 shows a perspective view of an example of a non-combustible aerosol provision system.
  • Figure 6 shows a section view of an example of a non-combustible aerosol provision system.
  • Figure 7 shows a perspective view of an example of a non-combustible aerosol provision system.
  • the aerosol-generating compositions described herein are compositions that are capable of generating aerosol, for example when heated, irradiated or energized in any other way.
  • the aerosol-generating composition may, for example, be in the form of a solid, liquid or gel which contain nicotine.
  • the aerosol-generating material may be an “amorphous solid”. In some embodiments, the amorphous solid is a “monolithic solid”.
  • the aerosol-generating material may be non-fibrous or fibrous. In some embodiments, the aerosol-generating material may be a dried gel.
  • the aerosol-generating material may be a solid material that may retain some fluid, such as liquid, within it.
  • the retained fluid may be water (such as water absorbed from the surroundings of the aerosol-generating material) or the retained fluid may be solvent (such as when the aerosol-generating material is formed from a slurry).
  • the solvent may be water.
  • the aerosol-generating composition may for example comprise from about 50wt%, 60wt% or 70wt% of aerosol-generating material, to about 90wt%,
  • wt% 95wt% or 100wt% of aerosol-generating material. These wt% values are calculated on a wet weight basis (WWB), i.e. including any water or other solvent present in the aerosol-generating composition or aerosol-generating material. In some cases, the aerosol-generating composition consists of aerosol-generating material.
  • WWB wet weight basis
  • the invention provides an aerosol-generating composition
  • an aerosol-generating composition comprising (or consisting of) an aerosol-generating material, wherein the aerosol-generating material comprises: about 1 to about 30 wt% nicotine; about 15 to about 80 wt% gelling agent; - about 10 to about 60 wt% aerosol-former material; about 1 to about 30 wt% acid; and optionally filler, wherein the wt% values are calculated on a dry weight basis; and wherein the molar ratio of nicotine to acid is 2.2:1 or less.
  • an aerosol-generating composition comprising (or consisting of) an aerosol-generating material, wherein the aerosol-generating material comprises: about 5 to about 30 wt% nicotine salt; about 15 to about 80 wt% gelling agent; about 10 to about 60 wt% aerosol-former material; and optionally filler, wherein the wt% values are calculated on a dry weight basis.
  • an aerosol-generating composition comprising (or consisting of) an aerosol-generating material, wherein the aerosol-generating material comprises: about 1 to about 30 wt% nicotine salt;
  • the presence of either an acid or a nicotine salt in the aerosol-generating material may improve the sensory attributes of the aerosol by reducing the harshness.
  • the acid protonates the nicotine to form a nicotine salt in situ, either in the material or in the aerosol once it is formed.
  • the presence of the nicotine salt results in an aerosol which some users find more satisfying.
  • the aerosol-generating material and/or the aerosol generating composition consists essentially of, or consists of, gelling agent; solvent; aerosol-former material; nicotine; acid; and optionally a flavour and/or optionally an additional active substance and/or optionally filler.
  • the aerosol-generating material and/or the aerosol generating composition consists essentially of, or consists of, gelling agent; solvent; aerosol-former material; nicotine; acid; and optionally a flavour and/or optionally filler.
  • the aerosol-generating material and/or the aerosol-generating composition consists essentially of, or consists of, gelling agent; solvent; aerosol- former material; nicotine; acid; and a flavour.
  • the aerosol-generating material and/or the aerosol-generating composition consists essentially of, or consists of, gelling agent; solvent; aerosol- former material; nicotine and acid. In some embodiments, the aerosol-generating material and/or the aerosol generating composition consists essentially of, or consists of, gelling agent; solvent; aerosol-former material; nicotine salt; and optionally a flavour and/or optionally an additional active substance and/or optionally filler.
  • the aerosol-generating material and/or the aerosol generating composition consists essentially of, or consists of, gelling agent; solvent; aerosol-former material; nicotine salt; and optionally a flavour and/or optionally filler.
  • the aerosol-generating material and/or the aerosol-generating composition consists essentially of, or consists of, gelling agent; solvent; aerosol- former material; nicotine salt; and a flavour.
  • the aerosol-generating material and/or the aerosol-generating composition consists essentially of, or consists of, gelling agent; solvent; aerosol- former material and nicotine salt.
  • the solvent may be water.
  • the aerosol generating material is a hydrogel and may comprise less than about 20 wt% of water calculated on a wet weight basis. In some cases, the hydrogel may comprise less than about 15 wt%, 12 wt% or 10 wt% of water calculated on a wet weight basis (WWB). In some cases, the hydrogel may comprise at least about 1 wt%, 2 wt% or at least about 5 wt% of water (WWB).
  • the water content of the aerosol generating material may be from about 5wt%, 7wt% or 9wt% to about 15wt%, 13wt% or llwt% (WWB), such as 5-15 wt%, 7-13 wt% or 9-11 wt% (WWB).
  • WWB llwt%
  • the water content of the aerosol-generating material may, for example, be determined by Karl-Fischer-titration or Gas Chromatography with Thermal Conductivity Detector (GC-TCD).
  • the aerosol-generating material may comprise one or more constituents capable of forming an aerosol.
  • the aerosol-generating material may comprise about 10 wt% to about 60 wt% of aerosol-former material (calculated on a dry weight basis), for example about 20 wt%, 25 wt% or 30 wt% to about 50 wt% or 55 wt%.
  • the aerosol-generating material comprises about 15 to about 60 wt% of aerosol-former material (calculated on a dry weight basis).
  • the aerosol-generating material comprises about 15-54 wt%, 20-50 wt%, 25-50 wt% or 30-50 wt% of an aerosol-former material.
  • the aerosol-former material may comprise one or more of glycerol, propylene glycol, diethylene glycol, triethylene glycol, tetraethylene glycol, 1,3-butylene glycol, erythritol, meso-Erythritol, ethyl vanillate, ethyl laurate, a diethyl suberate, triethyl citrate, triacetin, a diacetin mixture, benzyl benzoate, benzyl phenyl acetate, tributyrin, lauryl acetate, lauric acid, myristic acid, and propylene carbonate.
  • glycerol propylene glycol
  • diethylene glycol triethylene glycol
  • tetraethylene glycol 1,3-butylene glycol
  • erythritol meso-Erythritol
  • ethyl vanillate ethyl laurate
  • the aerosol former material comprises one or more polyhydric alcohols, such as glycerol, propylene glycol, triethylene glycol, 1,3- butanediol and glycerin; esters of polyhydric alcohols, such as glycerol mono-, di- or triacetate; and/or aliphatic esters of mono-, di- or polycarboxylic acids, such as dimethyl dodecanedioate and dimethyl tetradecanedioate.
  • polyhydric alcohols such as glycerol, propylene glycol, triethylene glycol, 1,3- butanediol and glycerin
  • esters of polyhydric alcohols such as glycerol mono-, di- or triacetate
  • aliphatic esters of mono-, di- or polycarboxylic acids such as dimethyl dodecanedioate and dimethyl tetradecanedioate.
  • the aerosol-former material comprises, consists essentially of or consists of glycerol and/or propylene glycol.
  • the aerosol-former material comprises a mixture of glycerol and propylene glycol in a weight ratio of glycerol to propylene glycol of about 3:1 to 1:3, about 2:1 to 1:2, about 1.5:1 to 1:1.5, about 55:45 to 45:55, or about 45:55.
  • the aerosol-former material comprises, consists essentially of or consists of glycerol.
  • the aerosol-generating material comprises about 15 wt% to about 80 wt% gelling agent, for example from about 20 wt%, 25 wt%, 30 wt%, 40 wt% or 45 wt% to about 65 wt%, 70 wt% or 75 wt% (all calculated on a dry weight basis).
  • the aerosol-generating material comprises about 20-80 wt%, 35-80 wt%, 45-80 wt%, 40-70 wt% or 45-70 wt% gelling agent.
  • the gelling agent comprises a hydrocolloid.
  • the gelling agent comprises (or is) one or more compounds selected from polysaccharide gelling agents, such as alginate, pectin, starch or a derivative thereof, cellulose or a derivative thereof, pullulan, carrageenan, agar and agarose; gelatin; gums, such as xanthan gum, guar gum and acacia gum; silica or silicone compounds, such as PDMS and sodium silicate; clays, such as kaolin; and polyvinyl alcohol.
  • polysaccharide gelling agents such as alginate, pectin, starch or a derivative thereof, cellulose or a derivative thereof, pullulan, carrageenan, agar and agarose
  • gelatin such as xanthan gum, guar gum and acacia gum
  • silica or silicone compounds such as PDMS and sodium silicate
  • clays such as kaolin
  • polyvinyl alcohol polyvinyl alcohol
  • the gelling agent comprises (or is) one or more polysaccharide gelling agents.
  • the polysaccharide gelling agent is selected from alginate, pectin, starch or a derivative thereof, cellulose or a derivative thereof, and combinations thereof.
  • the polysaccharide gelling agent is selected from alginate, a cellulose derivative and combinations thereof.
  • the gelling agent is a polysaccharide gelling agent, optionally wherein the polysaccharide gelling agent is selected from alginate, a cellulose derivative, and combinations thereof.
  • the alginate is sodium alginate.
  • the polysaccharide gelling agent is a cellulose derivative.
  • the polysaccharide gelling agent is alginate.
  • the gelling agent is not crosslinked.
  • the absence of crosslinks in the gelling agent facilitates quicker delivery of the constituent, derivative or extract of cannabis (and any optional additional active substances and/or flavours) from the aerosol-generating material.
  • cellulosic gelling agents include, but are not limited to, hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, carboxymethylcellulose (CMC), hydroxypropyl methylcellulose (HPMC), methyl cellulose, ethyl cellulose, cellulose acetate (CA), cellulose acetate butyrate (CAB), and cellulose acetate propionate (CAP).
  • the cellulose or derivative thereof is selected from hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, carboxymethylcellulose (CMC), hydroxypropyl methylcellulose (HPMC), methyl cellulose, ethyl cellulose, cellulose acetate (CA), cellulose acetate butyrate (CAB), and cellulose acetate propionate (CAP).
  • CMC carboxymethylcellulose
  • HPMC hydroxypropyl methylcellulose
  • CAP cellulose acetate propionate
  • the cellulose derivative is CMC.
  • the gelling agent comprises (or is) one or more of alginate, pectin, hydroxyethyl cellulose, hydroxypropyl cellulose, carboxymethylcellulose, pullulan, xanthan gum guar gum, carrageenan, agarose, acacia gum, fumed silica, PDMS, sodium silicate, kaolin and polyvinyl alcohol.
  • the gelling agent comprises (or is) one or more of hydroxyethyl cellulose, hydroxypropyl cellulose, carboxymethylcellulose, guar gum, acacia gum, alginate and/or pectin.
  • the gelling agent comprises (or is) alginate and/or pectin, and may be combined with a crosslinking agent (such as a calcium source) during formation of the aerosol-generating material.
  • a crosslinking agent such as a calcium source
  • the aerosol-generating material may comprise a calcium-crosslinked alginate and/or a calcium-crosslinked pectin.
  • the gelling agent comprises (or is) alginate.
  • alginate is the only gelling agent present in the aerosol-generating material.
  • the gelling agent comprises alginate and at least one further gelling agent, such as pectin.
  • the gelling agent is carboxymethylcellulose.
  • CMC is the only gelling agent present in the aerosol generating material.
  • the aerosol-generating composition comprises a crosslinking agent.
  • the crosslinking agent comprises calcium ions.
  • the aerosol-generating composition may comprise carboxymethyl cellulose and a calcium-crosslinked alginate.
  • the aerosol-generating composition does not comprise a crosslinking agent.
  • the aerosol-generating material comprises about 1 wt% to about 30 wt% nicotine, for example from about 3 wt% or 5 wt% to about 10 wt%, 15 wt%, 20 wt% or 25 wt% nicotine (all calculated on a dry weight basis). In exemplary embodiments, the aerosol-generating material comprises 5-30 wt%, 6-30 wt%, 1-20 wt%, 1-15 wt%, 1-10 wt% or 2-10 wt% nicotine.
  • the aerosol-generating material comprises about 1 wt% to about 30 wt% acid, for example from about 3 wt% or 5 wt% to about 10 wt%, 15 wt%, 20 wt% or 25 wt% acid (all calculated on a dry weight basis). In exemplary embodiments, the aerosol-generating material comprises 5-30 wt%, 6-30 wt%, 1-20 wt%, 1-15 wt%, 1-10 wt% or 2-10 wt% acid.
  • the acid is an organic acid.
  • the acid may be at least one of a monoprotic acid, diprotic acid and a triprotic acid.
  • the acid may contain at least one carboxy functional group.
  • the acid may be at least one of an alpha-hydroxy acid, carboxylic acid, dicarboxylic acid, tricarboxylic acid and keto acid.
  • the acid may be an alpha-keto acid.
  • the acid may be at least one of succinic acid, lactic acid, benzoic acid, citric acid, tartaric acid, fumaric acid, levulinic acid, acetic acid, malic acid, formic acid, sorbic acid, benzoic acid, propanoic acid and pyruvic acid.
  • the acid is at least one of lactic acid, benzoic acid, levulinic acid and pyruvic acid.
  • the acid is benzoic acid.
  • the acid is lactic acid.
  • the acid may be an inorganic acid.
  • the acid may be a mineral acid.
  • the acid may be at least one of sulphuric acid, hydrochloric acid, boric acid and phosphoric acid.
  • the aerosol-generating material comprises nicotine and an acid.
  • the molar ratio of nicotine to acid is 2.2:1 or less, 1.5:1 or less or 1:1 or less.
  • the molar ratio of nicotine to acid is 0.5:1 or more
  • the molar ratio is from 0.5 : 1 to 2.2:1, 0.7:1 to 2:1 or 0.7:1 to 1.5:1.
  • the molar ratio of acid to nicotine is 0.5:1 or more
  • the molar ratio of acid to nicotine is from 0.5:1 to 2.2:1, 0.7:1 to 2:1 or 0.7:1 to 1.5:1.
  • the aerosol-generating material comprises about 1 wt% to about 30 wt% nicotine salt, for example from about 3 wt% or 5 wt% to about 10 wt%, 15 wt%, 20 wt% or 25 wt% nicotine salt (all calculated on a dry weight basis).
  • the aerosol-generating material comprises 5-30 wt%, 6-30 wt%, 1-20 wt%, 1-15 wt%, 1-10 wt% or 2-10 wt% nicotine salt.
  • the nicotine salt comprises nicotine lactate or nicotine benzoate.
  • the nicotine salt comprises, consists essentially of or consists of nicotine benzoate.
  • the aerosol-generating material may further comprise a filler.
  • a filler may help to reduce tackiness of the aerosol-generating material, for example if high levels of aerosol-former material are present.
  • the aerosol-generating material comprises less than about 10 wt% of a filler, such as less than about 5 wt% filler (all calculated on a dry weight basis). In some embodiments, the aerosol-generating material comprises from about 1 wt%, 2 wt% or 3 wt% to about 5 wt%, 7 wt% or 10 wt%, such as 1-10 wt%, 2-7 wt% or 3-5 wt%.
  • the aerosol-generating material comprises less than 1 wt% of a filer.
  • the aerosol-generating material comprises no filler. In some cases, the aerosol-generating composition comprises no filler.
  • the filler may comprise one or more inorganic filler materials, such as calcium carbonate, perlite, vermiculite, diatomaceous earth, colloidal silica, magnesium oxide, magnesium sulphate, magnesium carbonate, and suitable inorganic sorbents, such as molecular sieves.
  • the filler if present, may comprise one or more organic filler materials such as wood pulp, cellulose and cellulose derivatives. In particular cases, aerosol-generating material comprises no calcium carbonate such as chalk.
  • the filler is fibrous.
  • the filler may be a fibrous organic filler material such as wood pulp, hemp fibre, cellulose or cellulose derivatives.
  • the filler comprises wood pulp.
  • fibrous filler in an aerosol-generating material may increase the tensile strength of the material. This may be particularly advantageous in examples wherein the aerosol-generating material is provided as a sheet, such as when an aerosol generating material sheet circumscribes a rod of aerosol-generating composition.
  • the aerosol-generating material may further comprise one or more other functional material(s).
  • nicotine or nicotine salt is or are the only active(s) present in the aerosol-generating material.
  • nicotine or nicotine salts is or are the only active(s) present in the aerosol-generating composition.
  • the aerosol-generating material and/or the aerosol generating composition may further comprise additional active ingredients
  • the aerosol-generating material may comprise from about 1 wt%, 5 wt%, 10 wt%, 15 wt%, 20 wt% or 25 wt% to about 65 wt%, 50 wt%, 45 wt%, 40 wt%, 35 wt% or 30 wt% (calculated on a dry weight basis) of another active substance in additional to nicotine or nicotine salt.
  • the additional active substance as used herein may be a physiologically active material, which is a material intended to achieve or enhance a physiological response.
  • the additional active substance may for example be selected from nutraceuticals, nootropics and psychoactives.
  • the additional active substance may be naturally occurring or synthetically obtained.
  • the additional active substance may comprise for example caffeine, taurine, theine, vitamins such as B6 or B12 or C, melatonin, or constituents, derivatives or combinations thereof.
  • the additional active substance may comprise one or more consistuents, derivatives or extracts of tobacco or another botanical.
  • the additional active substance comprises caffeine, melatonin or vitamin B 12.
  • the additional active substance comprises constituents(s), derivative(s) or extract(s) of cannabis.
  • the additional active substance comprises one or more cannabinoid compounds selected from the group consisting of: cannabidiol (CBD), tetrahydrocannabinol (THC), tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), cannabinol (CBN), cannabigerol (CBG), cannabichromene (CBC), cannabicyclol (CBL), cannabivarin (CBV), tetrahydrocannabivarin (THCV), cannabidivarin (CBDV), cannabichromevarin (CBCV), cannabigerovarin (CBGV), cannabigerol monomethyl ether (CBGM) and cannabielsoin (CBE), cannabicitran (CBT).
  • CBD cannabidiol
  • THC tetrahydrocannabinol
  • THCA tetrahydrocannabinolic acid
  • CBD
  • the additional active substance may comprise one or more cannabinoid compounds selected from the group consisting of cannabidiol (CBD) and THC (tetrahydrocannabinol).
  • CBD cannabidiol
  • THC tetrahydrocannabinol
  • the additional active substance solid may comprise cannabidiol (CBD).
  • CBD cannabidiol
  • the active substances may comprise nicotine and cannabidiol (CBD).
  • CBD cannabidiol
  • the active substances may comprise nicotine, cannabidiol (CBD), and THC (tetrahydrocannabinol).
  • the additional active substance may comprise or be derived from one or more botanicals or constituents, derivatives or extracts thereof.
  • botanical includes any material derived from plants including, but not limited to, extracts, leaves, bark, fibres, stems, roots, seeds, flowers, fruits, pollen, husk, shells or the like.
  • the material may comprise an active compound naturally existing in a botanical, obtained synthetically.
  • the material may be in the form of liquid, gas, solid, powder, dust, crushed particles, granules, pellets, shreds, strips, sheets, or the like.
  • Example botanicals are tobacco, eucalyptus, star anise, hemp, cocoa, coffee, fennel, lemongrass, peppermint, spearmint, rooibos, chamomile, flax, ginger, ginkgo biloba, hazel, hibiscus, laurel, licorice (liquorice), matcha, mate, orange skin, papaya, rose, sage, tea such as green tea or black tea, thyme, clove, cinnamon, coffee, aniseed (anise), basil, bay leaves, cardamom, coriander, cumin, nutmeg, oregano, paprika, rosemary, saffron, lavender, lemon peel, mint, juniper, elderflower, vanilla, wintergreen, beefsteak plant, curcuma, turmeric, sandalwood, cilantro, bergamot, orange blossom, myrtle, cassis, valerian, pimento, mace, damien, marjoram, olive, lemon
  • Mentha c.v. Mentha niliaca, Mentha piperita, Mentha piperita citrata c.v., Mentha piperita c.v., Mentha spicata crispa, Mentha car difolia, Mentha longifolia, Mentha suaveolens variegata, Mentha pulegium, Mentha spicata c.v. and Mentha suaveolens.
  • the additional active substance comprises or is derived from one or more botanicals or constituents, derivatives or extracts thereof and the botanical is tobacco.
  • the aerosol-generating material is substantially free from tobacco.
  • substantially free from it is meant that the material comprises less than 1 wt%, such as less than 0.5 wt% tobacco.
  • the aerosol-generating material is free from tobacco.
  • the aerosol generating material does not comprise tobacco fibres. In particular embodiments, the aerosol-generating material does not comprise fibrous material.
  • the additional active substance comprises or derives from one or more botanicals or constituents, derivatives or extracts thereof and the botanical is selected from eucalyptus, star anise, cocoa and hemp. In some embodiments the additional active substance comprises (or is) a botanical selected from eucalyptus, star anise, cocoa and hemp.
  • the additional active substance comprises or derived from one or more botanicals or constituents, derivatives or extracts thereof and the botanical is selected from rooibos and fennel. In some embodiments, the additional active substance comprises (or is) a botanical selected from rooibos and fennel.
  • the aerosol-generating material and/or the aerosol-generating composition may optionally comprise a flavour.
  • the aerosol-generating material may comprise up to about 65 wt%, 55 wt%, 50 wt% or 45 wt% of a flavour.
  • the aerosol-generating material may comprise at least about 0.1 wt%, 1 wt%, 10 wt%, 20 wt%, 30 wt%, 35 wt% or 40 wt% of a flavour (all calculated on a dry weight basis).
  • the aerosol-generating material may comprise 1-65 wt%, 10-65 wt%, 20-50 wt%, or 30-40 wt% a flavour.
  • flavour and “flavourant” refer to materials which, where local regulations permit, may be used to create a desired taste, aroma or other somatosensorial sensation in a product for adult consumers. They may include naturally occurring flavour materials, botanicals, extracts of botanicals, synthetically obtained materials, or combinations thereof (e.g., tobacco, cannabis, licorice (liquorice), hydrangea, eugenol, Japanese white bark magnolia leaf, chamomile, fenugreek, clove, maple, matcha, menthol, Japanese mint, aniseed (anise), cinnamon, turmeric, Indian spices, Asian spices, herb, wintergreen, cherry, berry, red berry, cranberry, peach, apple, orange, mango, clementine, lemon, lime, tropical fruit, papaya, rhubarb, grape, durian, dragon fruit, cucumber, blueberry, mulberry, citrus fruits, Drambuie, bourbon, scotch,
  • the flavour comprises menthol, spearmint and/or peppermint.
  • the flavour comprises flavour components of cucumber, blueberry, citrus fruits and/or redberry.
  • the flavour comprises eugenol.
  • the flavour comprises flavour components extracted from tobacco. In some embodiments, the flavour comprises flavour components extracted from cannabis.
  • the flavour may comprise a sensate, which is intended to achieve a somatosensorial sensation which are usually chemically induced and perceived by the stimulation of the fifth cranial nerve (trigeminal nerve), in addition to or in place of aroma or taste nerves, and these may include agents providing heating, cooling, tingling, numbing effect.
  • a suitable heat effect agent may be, but is not limited to, vanillyl ethyl ether and a suitable cooling agent may be, but not limited to eucolyptol or WS-3 (/V-ethyl-2-isopropyl-5- methylcyclohexanecarboxamide) .
  • the aerosol-generating material may additionally comprise an emulsifying agent, which emulsifies molten flavour during manufacture.
  • the aerosol-generating material may comprise from about 5 wt% to about 15 wt% of an emulsifying agent (calculated on a dry weight basis), suitably about 10wt%.
  • the emulsifying agent may comprise acacia gum.
  • the total content of additional active substance and/or flavour may be at least about 0.1 wt%, 1 wt%, 5 wt%, 10 wt%, 20 wt%, 25 wt% or 30 wt%. In some cases, the total content of additional active substance and/or flavour may be less than about 60 wt%, 50 wt% or 40 wt% (all calculated on a dry weight basis).
  • the aerosol-generating material may comprise a colourant.
  • the addition of a colourant may alter the visual appearance of the aerosol-generating material.
  • the presence of colourant in the aerosol-generating material may enhance the visual appearance of the aerosol-generating material and the aerosol-generating composition.
  • the aerosol generating material may be colour-matched to other components of the aerosol generating composition or to other components of an article comprising the aerosol generating material.
  • the colour of aerosol-generating material may be, for example, white, green, red, purple, blue, brown or black. Other colours are also envisaged. Natural or synthetic colourants, such as natural or synthetic dyes, food- grade colourants and pharmaceutical-grade colourants may be used.
  • the colourant is caramel, which may confer the aerosol-generating material with a brown appearance.
  • the colour of the aerosol generating material may be similar to the colour of other components (such as tobacco material) in an aerosol-generating composition comprising the aerosol generating material.
  • the addition of a colourant to the aerosol-generating material renders it visually indistinguishable from other components in the aerosol-generating composition.
  • the colourant may be incorporated during the formation of the aerosol generating material (e.g. when forming a slurry comprising the materials that form the aerosol-generating material) or it may be applied to the aerosol-generating material after its formation (e.g. by spraying it onto the aerosol-generating material).
  • the one or more other functional materials may comprise one or more of pH regulators, preservatives, stabilisers, and/or antioxidants.
  • the aerosol-generating material is formed as a sheet.
  • the aerosol-generating material sheet may be incorporated into the non-combustible aerosol provision system or consumable in sheet form.
  • the aerosol-generating material sheet may be incorporated as a planar sheet, as a gathered or bunched sheet, as a crimped sheet, as a rolled sheet (i.e. in the form of a tube), or as strips (e.g. formed by cutting the sheet into longitudinal strips).
  • the aerosol-generating material of these embodiments may be included in the system/consumable as a sheet, such as a sheet circumscribing a rod of aerosolisable material (e.g. tobacco).
  • the aerosol-generating material sheet may be formed on a wrapping paper which circumscribes an aerosolisable material such as tobacco.
  • the sheet may be shredded and then incorporated into the assembly, suitably mixed into an aerosolisable material such as cut rag tobacco.
  • the aerosol-generating material may be in the form of a sheet or layer having a thickness of about 0.015 mm to about 1.0 mm.
  • the thickness may be in the range of about 0.05 mm, 0.1 mm or 0.15 mm to about 0.5 mm or 0.3 mm, for example 0.1-3 mm or 0.15-3 mm.
  • a material having a thickness of 0.2 mm may be particularly suitable.
  • the aerosol-generating material may comprise more than one layer, and the thickness described herein refers to the aggregate thickness of those layers.
  • the aerosol-generating material is too thick, then heating efficiency may be compromised. This adversely affects the power consumption in use. Conversely, if the aerosol-generating material is too thin, it may be difficult to manufacture and handle; a very thin material is harder to cast and may be fragile, compromising aerosol formation in use.
  • the thickness stipulated herein is a mean thickness for the material.
  • the aerosol-generating material thickness may vary by no more than 25%, 20%, 15%, 10%, 5% or 1%.
  • the aerosol-generating material in sheet form may have a tensile strength of from around 200 N/m to around 2000 N/m. In some examples, the aerosol-generating material in sheet form may have a tensile strength of from around 200 N/m to around 900 N/m. In some examples, such as where the aerosol generating material does not comprise a filler, the aerosol-generating material in sheet form may have a tensile strength of from around 200 N/m to around 400 N/m, or around 200 N/m to around 300 N/m, or about 250 N/m.
  • Such tensile strengths may be particularly suitable for embodiments wherein the aerosol-generating material and/or the aerosol-generating composition is formed as a sheet and then shredded and incorporated into a consumable.
  • the aerosol-generating material may have a tensile strength of from around 600 N/m to around 900 N/m, or from around 700 N/m to around 900 N/m, or around 800 N/m.
  • Such tensile strengths may be particularly suitable for embodiments wherein the aerosol-generating material and/or the aerosol-generating composition is included in a consumable/non-combustible aerosol provision system as a rolled sheet, suitably in the form of a tube.
  • the aerosol-generating composition comprising the aerosol-generating material may have any suitable area density, such as from 30 g/m 2 to 120 g/m 2 .
  • the aerosol-generating material may have a mass per unit area of 80-120 g/m 2 , or from about 70 to 110 g/m 2 , or particularly from about 90 to 110 g/m 2 , or suitably about 100 g/m 2 (so that it has a similar density to cut rag tobacco and a mixture of these substances will not readily separate).
  • Such area densities may be particularly suitable where the aerosol-generating composition is included in assembly consumable/system in sheet form, or as a shredded sheet (described further hereinbelow).
  • the aerosol-generating composition may have a mass per unit area of about 30 to 70 g/m 2 , 40 to 60 g/m 2 , or 25-60 g/m 2 and may be used to wrap an aerosolisable material such as tobacco.
  • the aerosol-generating material is formed as a film on a support.
  • the aerosol-generating film may be a continuous film or a discontinuous film, such as an arrangement of discrete portions of film on a support. In some cases, the aerosol-generating film does not comprise a filler.
  • the aerosol-generating material for use in aerosol generation may be present on or in a support, to form a substrate.
  • the support may, for example, be or comprise paper, card, paperboard, cardboard, reconstituted material, a plastics material, a ceramic material, a composite material, glass, a metal, or a metal alloy.
  • the support comprises (or is) a susceptor.
  • the susceptor is an aluminium sheet.
  • the susceptor is embedded within the material.
  • the susceptor is on one or either side of the material.
  • the aerosol-generating composition may comprise a carrier on which the aerosol-generating material is provided.
  • the carrier functions as a support on which the aerosol-generating material layer forms, easing manufacture.
  • the carrier may provide tensile strength to the aerosol-generating material layer, easing handling.
  • the carrier may be formed from materials selected from metal foil, paper, carbon paper, greaseproof paper, ceramic, carbon allotropes such as graphite and graphene, plastic, cardboard, wood or combinations thereof.
  • the carrier may comprise or consist of a tobacco material, such as a sheet of reconstituted tobacco.
  • the carrier may be formed from materials selected from metal foil, paper, cardboard, wood or combinations thereof.
  • the carrier itself be a laminate structure comprising layers of materials selected from the preceding lists.
  • the carrier may also function as a flavour carrier.
  • the carrier may be impregnated with a flavour or with tobacco extract.
  • the carrier may be magnetic.
  • This functionality may be used to fasten the carrier to the non-combustible aerosol provision device in use, or may be used to generate particular aerosol-generating material shapes.
  • the aerosol-generating composition may comprise one or more magnets which can be used to fasten the material to an induction heater in use.
  • the carrier may be substantially or wholly impermeable to gas and/or aerosol. This prevents aerosol or gas passage through the carrier layer, thereby controlling the flow and ensuring it is delivered to the user. This can also be used to prevent condensation or other deposition of the gas/aerosol in use on, for example, the surface of a heater provided in an aerosol generating assembly. Thus, consumption efficiency and hygiene can be improved in some cases.
  • the surface of the carrier that abuts the aerosol-generating material may be porous.
  • the carrier comprises paper.
  • a porous carrier such as paper has been found to be particularly suitable; the porous (e.g. paper) layer abuts the aerosol-generating material layer and forms a strong bond.
  • the aerosol-generating material may be formed by drying a gel and, without being limited by theory, it is thought that the slurry from which the gel is formed partially impregnates the porous carrier (e.g. paper) so that when the gel sets, the carrier is partially bound into the gel. This provides a strong binding between the gel and the carrier (and between the dried gel and the carrier).
  • the aerosol-generating material may be laminated to a carrier, such as a paper sheet.
  • the layer of slurry may be formed on a carrier, such as a paper sheet.
  • surface roughness may contribute to the strength of bond between the aerosol-generating material and the carrier.
  • the paper roughness (for the surface abutting the carrier) may suitably be in the range of 50-1000 Bekk seconds, suitably 50-150 Bekk seconds, suitably 100 Bekk seconds (measured over an air pressure interval of 50.66-48.00 kPa).
  • a Bekk smoothness tester is an instrument used to determine the smoothness of a paper surface, in which air at a specified pressure is leaked between a smooth glass surface and a paper sample, and the time (in seconds) for a fixed volume of air to seep between these surfaces is the "Bekk smoothness”.
  • the surface of the carrier facing away from the aerosol generating material may be arranged in contact with the heater, and a smoother surface may provide more efficient heat transfer.
  • the carrier is disposed so as to have a rougher side abutting the aerosol-generating material and a smoother side facing away from the aerosol-generating material.
  • the carrier may be a paper-backed foil; the paper layer abuts the aerosol-generating material layer and the properties discussed in the previous paragraphs are afforded by this abutment.
  • the foil backing is substantially impermeable, providing control of the aerosol flow path.
  • a metal foil backing may also serve to conduct heat to the aerosol-generating material.
  • the foil layer of the paper-backed foil abuts the aerosol generating material.
  • the foil is substantially impermeable, thereby preventing water provided in the aerosol-generating material from being absorbed into the paper which could weaken its structural integrity.
  • the carrier is formed from or comprises metal foil, such as aluminium foil.
  • a metallic carrier may allow for better conduction of thermal energy to the aerosol-generating material.
  • a metal foil may function as a susceptor in an induction heating system.
  • the carrier comprises a metal foil layer and a support layer, such as cardboard.
  • the metal foil layer may have a thickness of less than 20 pm, such as from about 1 pm to about 10 pm, suitably about 5 pm.
  • the carrier may have a thickness of between about 0.010 mm and about 2.0 mm, suitably from about 0.015 mm, 0.02 mm, 0.05 mm or 0.1 mm to about 1.5 mm, 1.0 mm, or 0.5 mm.
  • a consumable for use in a non-combustible aerosol provision device comprising an aerosol generating composition
  • the aerosol-generating composition comprises (or consists of) an aerosol-generating material, the aerosol-generating material comprising: about 1 to about 30 wt% nicotine; about 15 to about 80 wt% gelling agent; about 10 to about 60 wt% aerosol-former material; about 1 to about 30 wt% acid; and - optionally filler, wherein the wt% values are calculated on a dry weight basis; and wherein the molar ratio of nicotine to acid is 2.2:1 or less.
  • a consumable for use in a non-combustible aerosol provision device comprising an aerosol-generating composition
  • the aerosol-generating composition comprises (or consists of) an aerosol-generating material, the aerosol-generating material comprising: about 5 to about 30 wt% nicotine salt; about 15 to about 80 wt% gelling agent; - about 10 to about 60 wt% aerosol-former material; and optionally filler, wherein the wt% values are calculated on a dry weight basis.
  • a consumable for use in a non-combustible aerosol provision device comprising an aerosol-generating composition
  • the aerosol-generating composition comprises (or consists of) an aerosol-generating material, the aerosol-generating material comprising: about 1 to about 30 wt% nicotine salt; about 45 to about 80 wt% gelling agent; - about 10 to about 54 wt% aerosol-former material; and optionally filler, wherein the wt% values are calculated on a dry weight basis.
  • the disclosure relates to consumables comprising aerosol-generating composition and configured to be used with non-combustible aerosol provision devices. These consumables are sometimes referred to as articles throughout the disclosure. The consumable may be used with any suitable non-combustible aerosol provision device.
  • a consumable is an article comprising or consisting of aerosol-generating composition, part or all of which is intended to be consumed during use by a user.
  • a consumable may comprise one or more other components, such as an aerosol-generating composition storage area, an aerosol-generating composition transfer component, an aerosol generation area, a housing, a wrapper, a mouthpiece, a filter and/or an aerosol-modifying agent.
  • a consumable may also comprise an aerosol generator, such as a heater, that emits heat to cause the aerosol-generating composition to generate aerosol in use.
  • the heater may, for example, comprise combustible material, a material heatable by electrical conduction, or a susceptor.
  • the consumable comprises a single aerosol-generating composition. That is, the consumable comprises an aerosol-generating composition as defined herein, and no other aerosol-generating component(s), active(s), agent(s) or composition(s).
  • the consumable is substantially free from tobacco.
  • substantially free from it is meant that the material comprises less than 1 wt%, such as less than 0.5 wt% tobacco.
  • the consumable is free from tobacco.
  • the consumable does not comprise tobacco fibres.
  • a susceptor is a material that is heatable by penetration with a varying magnetic field, such as an alternating magnetic field.
  • the susceptor may be an electric ally-conductive material, so that penetration thereof with a varying magnetic field causes induction heating of the heating material.
  • the heating material may be magnetic material, so that penetration thereof with a varying magnetic field causes magnetic hysteresis heating of the heating material.
  • the susceptor may be both electric ally-conductive and magnetic, so that the susceptor is heatable by both heating mechanisms.
  • the device that is configured to generate the varying magnetic field is referred to as a magnetic field generator, herein.
  • An aerosol-modifying agent is a substance, typically located downstream of the aerosol generation area, that is configured to modify the aerosol generated, for example by changing the taste, flavour, acidity or another characteristic of the aerosol.
  • the aerosol-modifying agent may be provided in an aerosol-modifying agent release component that is operable to selectively release the aerosol-modifying agent.
  • the aerosol-modifying agent may, for example, be an additive or a sorbent.
  • the aerosol-modifying agent may, for example, comprise one or more of a flavourant, a colourant, water, and a carbon adsorbent.
  • the aerosol-modifying agent may, for example, be a solid, a liquid, or a gel.
  • the aerosol-modifying agent may be in powder, thread or granule form.
  • the aerosol-modifying agent may be free from filtration material.
  • An aerosol generator is an apparatus configured to cause aerosol to be generated from the aerosol-generating material.
  • the aerosol generator is a heater configured to subject the aerosol-generating material to heat energy, so as to release one or more volatiles from the aerosol-generating composition to form an aerosol.
  • the aerosol generator is configured to cause an aerosol to be generated from the aerosol-generating composition without heating.
  • the aerosol generator may be configured to subject the aerosol-generating composition to one or more of vibration, increased pressure, or electrostatic energy.
  • a non-combustible aerosol provision system comprising the consumable described herein and a non combustible aerosol provision device.
  • a “non-combustible” aerosol provision system is one where a constituent aerosol-generating material of the aerosol provision system (or component thereof) is not combusted or burned in order to facilitate delivery of at least one substance to a user.
  • the delivery system is a non-combustible aerosol provision system, such as a powered non-combustible aerosol provision system.
  • the non-combustible aerosol provision system is an aerosol-generating material heating system, also known as a heat-not-burn system.
  • a heat-not-burn system An example of such a system is a tobacco heating system.
  • the non-combustible aerosol provision device is a heat-not-burn device.
  • the non-combustible aerosol provision system is a hybrid system to generate aerosol using a combination of aerosol-generating materials, one or a plurality of which may be heated.
  • the hybrid system comprises the aerosol-generating material described herein comprising or consisting of the aerosol-generating material and an additional liquid or gel aerosol-generating material.
  • the non-combustible aerosol provision device is an electronic tobacco hybrid device.
  • the non-combustible aerosol provision system may comprise a non-combustible aerosol provision device and a consumable for use with the non combustible aerosol provision device.
  • the non-combustible aerosol provision system such as a non-combustible aerosol provision device thereof, may comprise a power source and a controller.
  • the power source may, for example, be an electric power source or an exothermic power source.
  • the exothermic power source comprises a carbon substrate which may be energised so as to distribute power in the form of heat to an aerosol-generating material or to a heat transfer material in proximity to the exothermic power source.
  • the non-combustible aerosol provision system such as a non-combustible aerosol provision device thereof, may comprise an area for receiving the consumable, an aerosol generator, an aerosol generation area, a housing, a mouthpiece, a filter and/or an aerosol-modifying agent.
  • the non-combustible aerosol provision system or device may comprise a heater configured to heat but not bum the aerosol generating substrate.
  • the heater may be, in some cases, a thin film, electrically resistive heater. In other cases, the heater may comprise an induction heater or the like. In yet further cases, the heater may be a combustible heat source or a chemical heat source which undergoes an exothermic reaction to produce heat in use.
  • the heater may heat but not bum the aerosolisable material(s) to between 120°C and 350°C in use. In some cases, the heater may heat but not burn the aerosolisable material(s) to between 140°C and 250°C in use. In some cases in use, substantially all of the aerosol-generating material is less than about 4 mm, 3 mm, 2 mm or 1 mm from the heater. In some cases, the solid is disposed between about 0.017 mm and 2.0 mm from the heater, suitably between about 0.1 mm and 1.0 mm. These minimum distances may, in some cases, reflect the thickness of a carrier that supports the aerosol-generating material. In some cases, a surface of the aerosol-generating material may directly abut the heater.
  • the heater may be embedded in the aerosol-generating material.
  • the heater may be an electrically resistive heater (with exposed contacts for connection to an electrical circuit).
  • the heater may be a susceptor embedded in the aerosol-generating material, which is heated by induction.
  • the non-combustible aerosol provision system may additionally comprise a cooling element and/or a filter.
  • the cooling element if present, may act or function to cool gaseous or aerosol components. In some cases, it may act to cool gaseous components such that they condense to form an aerosol. It may also act to space the very hot parts of the apparatus from the user.
  • the filter if present, may comprise any suitable filter known in the art such as a cellulose acetate plug.
  • the non-combustible aerosol provision system may be a heat- not-bum system. That is, it may contain a solid material (and no liquid aerosolisable material).
  • a heat-not-bum device is disclosed in WO 2015/062983 A2, which is incorporated by reference in its entirety.
  • the non-combustible aerosol provision system may comprise an electronic tobacco hybrid device. That is, it may contain a solid aerosolisable material and a liquid aerosolisable material.
  • the separate aerosolisable materials may be heated by separate heaters, the same heater or, in one case, a downstream aerosolisable material may be heated by a hot aerosol which is generated from the upstream aerosolisable material.
  • An electronic tobacco hybrid device is disclosed in WO 2016/135331 Al, which is incorporated by reference in its entirety.
  • the consumable may alternatively be referred to herein as a cartridge.
  • the consumable may be adapted for use in a THP, an electronic tobacco hybrid device or another aerosol generating device.
  • the consumable may additionally comprise a filter and/or cooling element, as described previously.
  • the consumable may be circumscribed by a wrapping material such as paper.
  • the consumable may additionally comprise ventilation apertures. These may be provided in the sidewall of the article. In some cases, the ventilation apertures may be provided in the filter and/or cooling element. These apertures may allow cool air to be drawn into the article during use, which can mix with the heated volatilised components thereby cooling the aerosol.
  • the ventilation enhances the generation of visible heated volatilised components from the article when it is heated in use.
  • the heated volatilised components are made visible by the process of cooling the heated volatilised components such that supersaturation of the heated volatilised components occurs.
  • the heated volatilised components then undergo droplet formation, otherwise known as nucleation, and eventually the size of the aerosol particles of the heated volatilised components increases by further condensation of the heated volatilised components and by coagulation of newly formed droplets from the heated volatilised components.
  • the ratio of the cool air to the sum of the heated volatilised components and the cool air is at least 15%.
  • a ventilation ratio of 15% enables the heated volatilised components to be made visible by the method described above. The visibility of the heated volatilised components enables the user to identify that the volatilised components have been generated and adds to the sensory experience of the smoking experience.
  • the ventilation ratio is between 50% and 85% to provide additional cooling to the heated volatilised components. In some cases, the ventilation ratio may be at least 60% or 65%.
  • FIG. 1 and 2 there are shown a partially cut-away section view and a perspective view of an example of article consumable 101 (“article”).
  • the article 101 is adapted for use with a device having a power source and a heater.
  • the article 101 of this embodiment is particularly suitable for use with the device 1 shown in Figures 5 to 7, described below.
  • the article 101 may be removably inserted into the device shown in Figure 5 at an insertion point 20 of the device 1.
  • the article 101 of one example is in the form of a substantially cylindrical rod that includes a body of aerosol-generating composition 103 and a filter assembly 105 in the form of a rod.
  • the aerosol-generating material comprises the aerosol-generating material described herein. In some embodiments, it may be included in sheet form.
  • the aerosol-generating material described herein may be incorporated in sheet form and in shredded form.
  • the filter assembly 105 includes three segments, a cooling segment 107, a filter segment 109 and a mouth end segment 111.
  • the article 101 has a first end 113, also known as a mouth end or a proximal end and a second end 115, also known as a distal end.
  • the body of aerosol-generating composition 103 is located towards the distal end 115 of the article 101.
  • the cooling segment 107 is located adjacent the body of aerosol-generating composition 103 between the body of aerosol-generating composition 103 and the filter segment 109, such that the cooling segment 107 is in an abutting relationship with the aerosol generating- composition 103 and the filter segment 103.
  • the filter segment 109 is located in between the cooling segment 107 and the mouth end segment 111.
  • the mouth end segment 111 is located towards the proximal end 113 of the article 101, adjacent the filter segment 109.
  • the filter segment 109 is in an abutting relationship with the mouth end segment 111.
  • the total length of the filter assembly 105 is between 37 mm and 45 mm, more preferably, the total length of the filter assembly 105 is 41 mm.
  • the rod of aerosol-generating composition 103 is between 34 mm and 50 mm in length, suitably between 38 mm and 46 mm in length, suitably 42 mm in length.
  • the total length of the article 101 is between 71 mm and 95 mm, suitably between 79 mm and 87 mm, suitably 83 mm.
  • An axial end of the body of aerosol-generating composition 103 is visible at the distal end 115 of the article 101.
  • the distal end 115 of the article 101 may comprise an end member (not shown) covering the axial end of the body of aerosol-generating composition 103.
  • the body of aerosol-generating composition 103 is joined to the filter assembly 105 by annular tipping paper (not shown), which is located substantially around the circumference of the filter assembly 105 to surround the filter assembly 105 and extends partially along the length of the body of aerosol-generating composition 103.
  • the tipping paper is made of 58GSM standard tipping base paper.
  • the tipping paper has a length of between 42mm and 50mm, suitably of 46mm.
  • the cooling segment 107 is an annular tube and is located around and defines an air gap within the cooling segment.
  • the air gap provides a chamber for heated volatilised components generated from the body of aerosol generating composition 103 to flow.
  • the cooling segment 107 is hollow to provide a chamber for aerosol accumulation yet rigid enough to withstand axial compressive forces and bending moments that might arise during manufacture and whilst the article 101 is in use during insertion into the device 1.
  • the thickness of the wall of the cooling segment 107 is approximately 0.29mm.
  • the cooling segment 107 provides a physical displacement between the aerosol generating composition 103 and the filter segment 109.
  • the physical displacement provided by the cooling segment 107 will provide a thermal gradient across the length of the cooling segment 107.
  • the cooling segment 107 is configured to provide a temperature differential of at least 40 degrees Celsius between a heated volatilised component entering a first end of the cooling segment 107 and a heated volatilised component exiting a second end of the cooling segment 107.
  • the cooling segment 107 is configured to provide a temperature differential of at least 60 degrees Celsius between a heated volatilised component entering a first end of the cooling segment 107 and a heated volatilised component exiting a second end of the cooling segment 107.
  • This temperature differential across the length of the cooling element 107 protects the temperature sensitive filter segment 109 from the high temperatures of the aerosol-generating composition 103 when it is heated by the device 1. If the physical displacement was not provided between the filter segment 109 and the body of aerosol-generating composition 103 and the heating elements of the device 1, then the temperature sensitive filter segment may 109 become damaged in use, so it would not perform its required functions as effectively.
  • the length of the cooling segment 107 is at least 15mm. In one example, the length of the cooling segment 107 is between 20mm and 30mm, more particularly 23mm to 27mm, more particularly 25mm to 27mm, suitably 25 mm.
  • the cooling segment 107 is made of paper, which means that it is comprised of a material that does not generate compounds of concern, for example, toxic compounds when in use adjacent to the heater of the device 1.
  • the cooling segment 107 is manufactured from a spirally wound paper tube which provides a hollow internal chamber yet maintains mechanical rigidity. Spirally wound paper tubes are able to meet the tight dimensional accuracy requirements of high-speed manufacturing processes with respect to tube length, outer diameter, roundness and straightness.
  • the cooling segment 107 is a recess created from stiff plug wrap or tipping paper.
  • the stiff plug wrap or tipping paper is manufactured to have a rigidity that is sufficient to withstand the axial compressive forces and bending moments that might arise during manufacture and whilst the article 101 is in use during insertion into the device 1.
  • the filter segment 109 may be formed of any filter material sufficient to remove one or more volatilised compounds from heated volatilised components from the aerosol-generating material.
  • the filter segment 109 is made of a mono-acetate material, such as cellulose acetate.
  • the filter segment 109 provides cooling and irritation-reduction from the heated volatilised components without depleting the quantity of the heated volatilised components to an unsatisfactory level for a user.
  • a capsule (not illustrated) may be provided in filter segment 109. It may be disposed substantially centrally in the filter segment 109, both across the filter segment 109 diameter and along the filter segment 109 length. In other cases, it may be offset in one or more dimension.
  • the capsule may in some cases, where present, contain a volatile component such as a flavour or aerosol- former material.
  • the density of the cellulose acetate tow material of the filter segment 109 controls the pressure drop across the filter segment 109, which in turn controls the draw resistance of the article 101. Therefore the selection of the material of the filter segment 109 is important in controlling the resistance to draw of the article 101. In addition, the filter segment performs a filtration function in the article 101.
  • the filter segment 109 is made of a 8Y15 grade of filter tow material, which provides a filtration effect on the heated volatilised material, whilst also reducing the size of condensed aerosol droplets which result from the heated volatilised material.
  • the presence of the filter segment 109 provides an insulating effect by providing further cooling to the heated volatilised components that exit the cooling segment 107. This further cooling effect reduces the contact temperature of the user’s lips on the surface of the filter segment 109.
  • the filter segment 109 is between 6mm to 10mm in length, suitably 8mm.
  • the mouth end segment 111 is an annular tube and is located around and defines an air gap within the mouth end segment 111.
  • the air gap provides a chamber for heated volatilised components that flow from the filter segment 109.
  • the mouth end segment 111 is hollow to provide a chamber for aerosol accumulation yet rigid enough to withstand axial compressive forces and bending moments that might arise during manufacture and whilst the article is in use during insertion into the device 1.
  • the thickness of the wall of the mouth end segment 111 is approximately 0.29mm.
  • the length of the mouth end segment 111 is between 6mm to 10mm, suitably 8mm.
  • the mouth end segment 111 may be manufactured from a spirally wound paper tube which provides a hollow internal chamber yet maintains critical mechanical rigidity. Spirally wound paper tubes are able to meet the tight dimensional accuracy requirements of high-speed manufacturing processes with respect to tube length, outer diameter, roundness and straightness. The mouth end segment 111 provides the function of preventing any liquid condensate that accumulates at the exit of the filter segment 109 from coming into direct contact with a user.
  • the mouth end segment 111 and the cooling segment 107 may be formed of a single tube and the filter segment 109 is located within that tube separating the mouth end segment 111 and the cooling segment 107.
  • FIGS 3 and 4 there are shown a partially cut-away section and perspective views of an example of an article 301.
  • the reference signs shown in Figures 3 and 4 are equivalent to the reference signs shown in Figures 1 and 2, but with an increment of 200.
  • a ventilation region 317 is provided in the article 301 to enable air to flow into the interior of the article 301 from the exterior of the article 301.
  • the ventilation region 317 takes the form of one or more ventilation holes 317 formed through the outer layer of the article 301.
  • the ventilation holes may be located in the cooling segment 307 to aid with the cooling of the article 301.
  • the ventilation region 317 comprises one or more rows of holes, and preferably, each row of holes is arranged circumferentially around the article 301 in a cross-section that is substantially perpendicular to a longitudinal axis of the article 301.
  • each row of ventilation holes may have between 12 to 36 ventilation holes 317.
  • the ventilation holes 317 may, for example, be between 100 to 500pm in diameter.
  • an axial separation between rows of ventilation holes 317 is between 0.25mm and 0.75mm, suitably 0.5mm.
  • the ventilation holes 317 are of uniform size. In another example, the ventilation holes 317 vary in size.
  • the ventilation holes can be made using any suitable technique, for example, one or more of the following techniques: laser technology, mechanical perforation of the cooling segment 307 or pre -perforation of the cooling segment 307 before it is formed into the article 301.
  • the ventilation holes 317 are positioned so as to provide effective cooling to the article 301.
  • the rows of ventilation holes 317 are located at least 11 m from the proximal end 313 of the article, suitably between 17mm and 20mm from the proximal end 313 of the article 301. The location of the ventilation holes 317 is positioned such that user does not block the ventilation holes 317 when the article 301 is in use.
  • Providing the rows of ventilation holes between 17mm and 20mm from the proximal end 313 of the article 301 enables the ventilation holes 317 to be located outside of the device 1, when the article 301 is fully inserted in the device 1, as can be seen in Figures 6 and 7.
  • By locating the ventilation holes outside of the device non-heated air is able to enter the article 301 through the ventilation holes from outside the device 1 to aid with the cooling of the article 301.
  • the length of the cooling segment 307 is such that the cooling segment 307 will be partially inserted into the device 1, when the article 301 is fully inserted into the device 1.
  • the length of the cooling segment 307 provides a first function of providing a physical gap between the heater arrangement of the device 1 and the heat sensitive filter arrangement 309, and a second function of enabling the ventilation holes 317 to be located in the cooling segment, whilst also being located outside of the device 1, when the article 301 is fully inserted into the device 1.
  • the majority of the cooling element 307 is located within the device 1. However, there is a portion of the cooling element 307 that extends out of the device 1. It is in this portion of the cooling element 307 that extends out of the device 1 in which the ventilation holes 317 are located.
  • FIG. 5 to 7 there is shown an example of a device 1 arranged to heat aerosol-generating composition to volatilise at least one component of said aerosol-generating material, typically to form an aerosol which can be inhaled.
  • the device 1 is a heating device which releases compounds by heating, but not burning, the aerosol-generating material.
  • a first end 3 is sometimes referred to herein as the mouth or proximal end 3 of the device 1 and a second end 5 is sometimes referred to herein as the distal end 5 of the device 1.
  • the device 1 has an on/off button 7 to allow the device 1 as a whole to be switched on and off as desired by a user.
  • the device 1 comprises a housing 9 for locating and protecting various internal components of the device 1.
  • the housing 9 comprises a uni-body sleeve 11 that encompasses the perimeter of the device 1, capped with a top panel 17 which defines generally the ‘top’ of the device 1 and a bottom panel 19 which defines generally the ‘bottom’ of the device 1.
  • the housing comprises a front panel, a rear panel and a pair of opposite side panels in addition to the top panel 17 and the bottom panel 19.
  • the top panel 17 and/or the bottom panel 19 may be removably fixed to the uni-body sleeve 11, to permit easy access to the interior of the device 1, or may be “permanently” fixed to the uni-body sleeve 11, for example to deter a user from accessing the interior of the device 1.
  • the panels 17 and 19 are made of a plastics material, including for example glass-filled nylon formed by injection moulding, and the uni-body sleeve 11 is made of aluminium, though other materials and other manufacturing processes may be used.
  • the top panel 17 of the device 1 has an opening 20 at the mouth end 3 of the device 1 through which, in use, the article 101, 301 including the aerosol-generating material may be inserted into the device 1 and removed from the device 1 by a user.
  • the housing 9 has located or fixed therein a heater arrangement 23, control circuitry 25 and a power source 27.
  • the heater arrangement 23, the control circuitry 25 and the power source 27 are laterally adjacent (that is, adjacent when viewed from an end), with the control circuitry 25 being located generally between the heater arrangement 23 and the power source 27, though other locations are possible.
  • the control circuitry 25 may include a controller, such as a microprocessor arrangement, configured and arranged to control the heating of the aerosol generating material in the article 101, 301 as discussed further below.
  • a controller such as a microprocessor arrangement
  • the power source 27 may be for example a battery, which may be a rechargeable battery or a non-rechargeable battery.
  • suitable batteries include for example a lithium-ion battery, a nickel battery (such as a nickel- cadmium battery), an alkaline battery and/ or the like.
  • the battery 27 is electrically coupled to the heater arrangement 23 to supply electrical power when required and under control of the control circuitry 25 to heat the aerosol-generating material in the article (as discussed, to volatilise the aerosol-generating material without causing the aerosol-generating material to burn).
  • An advantage of locating the power source 27 laterally adjacent to the heater arrangement 23 is that a physically large power source 25 may be used without causing the device 1 as a whole to be unduly lengthy.
  • a physically large power source 25 has a higher capacity (that is, the total electrical energy that can be supplied, often measured in Amp-hours or the like) and thus the battery life for the device 1 can be longer.
  • the heater arrangement 23 is generally in the form of a hollow cylindrical tube, having a hollow interior heating chamber into which the article 101, 301 comprising the aerosol-generating composition is inserted for heating in use.
  • the heater arrangement 23 may comprise a single heating element or may be formed of plural heating elements aligned along the longitudinal axis of the heater arrangement 23.
  • the or each heating element may be annular or tubular, or at least part-annular or part-tubular around its circumference.
  • the or each heating element may be a thin film heater.
  • the or each heating element may be made of a ceramics material.
  • suitable ceramics materials include alumina and aluminium nitride and silicon nitride ceramics, which may be laminated and sintered.
  • Other heating arrangements are possible, including for example inductive heating, infrared heater elements, which heat by emitting infrared radiation, or resistive heating elements formed by for example a resistive electrical winding.
  • the heater arrangement 23 is supported by a stainless steel support tube and comprises a polyimide heating element.
  • the heater arrangement 23 is dimensioned so that substantially the whole of the body of aerosol-generating composition 103, 303 of the article 101, 301 is inserted into the heater arrangement 23 when the article 101, 301 is inserted into the device 1.
  • the or each heating element may be arranged so that selected zones of the aerosol-generating material can be independently heated, for example in turn (over time, as discussed above) or together (simultaneously) as desired.
  • the heater arrangement 23 in this example is surrounded along at least part of its length by a thermal insulator 31.
  • the insulator 31 helps to reduce heat passing from the heater arrangement 23 to the exterior of the device 1. This helps to keep down the power requirements for the heater arrangement 23 as it reduces heat losses generally.
  • the insulator 31 also helps to keep the exterior of the device 1 cool during operation of the heater arrangement 23.
  • the insulator 31 may be a double-walled sleeve which provides a low pressure region between the two walls of the sleeve.
  • the insulator 31 may be for example a “vacuum” tube, i.e. a tube that has been at least partially evacuated so as to minimise heat transfer by conduction and/or convection.
  • a “vacuum” tube i.e. a tube that has been at least partially evacuated so as to minimise heat transfer by conduction and/or convection.
  • Other arrangements for the insulator 31 are possible, including using heat insulating materials, including for example a suitable foam-type material, in addition to or instead of a double- walled sleeve.
  • the housing 9 may further comprises various internal support structures 37 for supporting all internal components, as well as the heating arrangement 23.
  • the device 1 further comprises a collar 33 which extends around and projects from the opening 20 into the interior of the housing 9 and a generally tubular chamber 35 which is located between the collar 33 and one end of the vacuum sleeve 31.
  • the chamber 35 further comprises a cooling structure 35f, which in this example, comprises a plurality of cooling fins 35f spaced apart along the outer surface of the chamber 35, and each arranged circumferentially around outer surface of the chamber 35.
  • the air gap 36 is around all of the circumference of the article 101, 301 over at least part of the cooling segment 307.
  • the collar 33 comprises a plurality of ridges 60 arranged circumferentially around the periphery of the opening 20 and which project into the opening 20.
  • the ridges 60 take up space within the opening 20 such that the open span of the opening 20 at the locations of the ridges 60 is less than the open span of the opening 20 at the locations without the ridges 60.
  • the ridges 60 are configured to engage with an article 101, 301 inserted into the device to assist in securing it within the device 1.
  • Open spaces (not shown in the Figures) defined by adjacent pairs of ridges 60 and the article 101, 301 form ventilation paths around the exterior of the article 101, 301. These ventilation paths allow hot vapours that have escaped from the article 101,
  • the article 101, 301 is removably inserted into an insertion point 20 of the device 1, as shown in Figures 5 to 7.
  • the body of aerosol-generating composition 103, 303 which is located towards the distal end 115, 315 of the article 101, 301, is entirely received within the heater arrangement 23 of the device 1.
  • the proximal end 113, 313 of the article 101, 301 extends from the device 1 and acts as a mouthpiece assembly for a user.
  • the heater arrangement 23 will heat the article 101, 301 to volatilise at least one component of the aerosol-generating compostion from the body of aerosol generating material 103, 303.
  • the primary flow path for the heated volatilised components from the body of aerosol-generating composition 103, 303 is axially through the article 101, 301, through the chamber inside the cooling segment 107, 307, through the filter segment 109, 309, through the mouth end segment 111, 311 to the user.
  • the temperature of the heated volatilised components that are generated from the body of aerosol-generating material is between 60°C and 250°C, which may be above the acceptable inhalation temperature for a user. As the heated volatilised component travels through the cooling segment 107, 307, it will cool and some volatilised components will condense on the inner surface of the cooling segment 107, 307.
  • cool air will be able to enter the cooling segment 307 via the ventilation holes 317 formed in the cooling segment 307. This cool air will mix with the heated volatilised components to provide additional cooling to the heated volatilised components.
  • an aerosol-generating material comprising: about 1 to about 30 wt% nicotine; about 15 to about 80 wt% gelling agent; about 10 to about 60 wt% aerosol-former material; about 1 to about 30 wt% acid; and optionally filler, wherein the wt% values are calculated on a dry weight basis; and wherein the molar ratio of nicotine to acid is 2.2:1 or less; the method comprising:
  • an aerosol-generating material comprising: about 5 to about 30 wt% nicotine salt; about 15 to about 80 wt% gelling agent; about 10 to about 60 wt% aerosol-former material; and optionally filler, wherein the wt% values are calculated on a dry weight basis; the method comprising:
  • an aerosol generating material comprising: about 1 to about 30 wt% nicotine salt; about 45 to about 80 wt% gelling agent; about 10 to about 54 wt% aerosol-former material; and optionally filler, wherein the wt% values are calculated on a dry weight basis; the method comprising:
  • Another aspect of the invention provides a method of making the consumable or system as previously described.
  • This method comprises a method of making the aerosol-generating material and incorporating the aerosol-generating material into the consumable or system.
  • the method may comprise (a) forming a slurry comprising components of the aerosol-generating material or precursors thereof, (b) forming a layer of the slurry, and (c) optionally setting or cross-linking the slurry,
  • step (a) the nicotine or nicotine salt may first be dissolved in the aerosol- former material and the resulting solution then added to the other components of the slurry.
  • the step (b) in the above methods of forming a layer of the slurry may comprise spraying, casting or extruding the slurry, for example.
  • the layer is formed by electrospraying the slurry.
  • the layer is formed by casting the slurry.
  • the steps (b) and/or (c) and/or (d) may, at least partially, occur simultaneously (for example, during electrospraying). In some cases, these steps may occur sequentially.
  • a setting or cross-linking agent such as a calcium source
  • a setting or cross-linking agent may be added to the slurry before or during step (b). This is appropriate in instances where gelation occurs relatively slowly (e.g. with alginate gelling agent), and thus the slurry may be, e.g. cast, after the setting agent is added.
  • step (c) of setting or cross-linking the slurry may comprise the addition of a setting or cross-linking agent to the slurry layer.
  • the setting or cross- linking agent may be sprayed onto the slurry, for example, or may be preloaded onto the surface on which the slurry is layered.
  • a setting or cross-linking agent comprising a calcium source (such as calcium chloride or calcium citrate), may be added to a slurry containing alginate and/or pectin to form a calcium-crosslinked alginate/pectin gel.
  • a calcium source such as calcium chloride or calcium citrate
  • the calcium should be added after casting (because the slurry is too viscous to cast).
  • the total amount of the setting or cross-linking agent such as a calcium source, may be 0.5-5 wt% (calculated on a dry weight basis). It has been found that the addition of too little setting or cross-linking agent may result in a gel which does not stabilise any optional flavour and results in the flavour dropping out of the gel. It has also been found that the addition of too much setting agent or cross-linking results in a gel that is very tacky or very brittle and consequently has poor handleability.
  • Alginate salts are derivatives of alginic acid and are typically high molecular weight polymers (10-600 kDa).
  • Alginic acid is a copolymer of b-D-mannuronic (M) and a-L-guluronic acid (G) units (blocks) linked together with (l,4)-glycosidic bonds to form a polysaccharide.
  • M b-D-mannuronic
  • G a-L-guluronic acid
  • Alginate salts with a high G monomer content may more readily form a gel on addition of the calcium source.
  • the gel-precursor may comprise an alginate salt in which at least about 40%, 45%, 50%, 55%, 60% or 70% of the monomer units in the alginate copolymer are a-L-guluronic acid (G) units.
  • G a-L-guluronic acid
  • the slurry may be warmed prior to and during casting. This can slow gelation, improving handleability and easing the casting process. Further, warming the slurry may melt optional flavour components (e.g. menthol) easing handleability.
  • optional flavour components e.g. menthol
  • menthol or other optional flavours may be distributed through the slurry in powder form.
  • menthol or other flavours may be molten in the slurry (where it is warmed).
  • an emulsifying agent such as acacia gum may be added to disperse molten menthol in the slurry.
  • the slurry may be cast onto a bandcast sheet. The sheet may be loaded with a releasing agent, such as lecithin, which can aid separation of the bandcast and the aerosol-generating material.
  • a slurry comprising: about 1 to about 30 wt% nicotine; about 15 to about 80 wt% gelling agent; about 10 to about 60 wt% aerosol-former material; about 1 to about 30 wt% acid; and optionally filler, wherein the wt% values are calculated on a dry weight basis; and wherein the molar ratio of nicotine to acid is 2.2:1 or less; and a solvent.
  • a slurry comprising: about 5 to about 30 wt% nicotine salt; about 15 to about 80 wt% gelling agent; about 10 to about 60 wt% aerosol-former material; and optionally filler, wherein the wt% values are calculated on a dry weight basis; and a solvent.
  • a slurry comprising: about 1 to about 30 wt% nicotine salt; about 45 to about 80 wt% gelling agent; about 10 to about 54 wt% aerosol-former material; and optionally filler, wherein the wt% values are calculated on a dry weight basis; and a solvent.
  • the slurry solvent comprises, or is, one or more of water, ethanol, methanol, dimethyl sulfoxide, acetone, hexane, and toluene.
  • the slurry solvent may comprise water.
  • the slurry solvent may consist essentially of or consist of water.
  • the slurry may comprise from about 50 wt%, 60 wt%, 70 wt%, 80 wt% or 90 wt% of solvent (WWB).
  • WWB solvent
  • the slurry has a viscosity of from about 1 to about 20 Pa-s at 46.5 °C, such as from about 10 to about 20 Pa-s at 46.5 °C, such as from about 14 to about 16 Pa-s at 46.5 °C.
  • An aerosol-generating material comprising: about 1 to about 30 wt% nicotine; about 15 to about 80 wt% gelling agent; about 10 to about 60 wt% aerosol-former material; about 1 to about 30 wt% acid; and optionally filler wherein the wt% values are calculated on a dry weight basis; and wherein the molar ratio of nicotine to acid is 2.2:1 or less.
  • a slurry comprising: about 1 to about 30 wt% nicotine; about 15 to about 80 wt% gelling agent; about 10 to about 60 wt% aerosol-former material; about 1 to about 30 wt% of an acid; and optionally filler wherein the wt% values are calculated on a dry weight basis; and wherein the molar ratio of nicotine to acid is 2.2:1 or less, and a solvent.
  • Embodiment 1 or the slurry of Embodiment 1A, comprising about 1-15 wt% nicotine.
  • Embodiment 3 The aerosol-generating material or slurry of Embodiment 2, comprising about 1-10 wt% nicotine.
  • Embodiment 1 or the slurry of Embodiment 1A, comprising about 3-15wt% nicotine.
  • the aerosol-generating material or slurry of Embodiment 4 comprising about 3-10 wt% nicotine.
  • the aerosol-generating material of Embodiment 1 or the slurry of Embodiment 1A comprising about 5-15 wt% nicotine.
  • Embodiment 6 The aerosol-generating material or slurry of Embodiment 6, comprising about 5-10 wt% nicotine.
  • the aerosol-generating material or slurry of Embodiment 8 comprising about 1-10 wt% acid.
  • the aerosol-generating material or slurry of Embodiment 8 comprising about 3- 15wt% acid.
  • the aerosol-generating material or slurry of Embodiment 10 comprising about 3- 10 wt% acid.
  • the aerosol-generating material or slurry of Embodiment 10 comprising about 5- 15 wt% acid.
  • the aerosol-generating material or slurry of Embodiment 9 comprising about 5- 10 wt% acid.
  • the acid comprises at least one of succinic acid, lactic acid, benzoic acid, citric acid, tartartic acid, fumaric acid, levulinic acid, acetic acid, malic acid, formic acid, sorbic acid, benzoic acid, propanoic acid and pyruvic acid.
  • An aerosol-generating material comprising: about 5 to about 30 wt% nicotine salt; about 15 to about 80 wt% gelling agent; about 10 to about 60 wt% aerosol-former material; and optionally filler wherein the wt% values are calculated on a dry weight basis.
  • An slurry comprising: about 5 to about 30 wt% nicotine salt; about 15 to about 80 wt% gelling agent; about 10 to about 60 wt% aerosol-former material; optionally filler wherein the wt% values are calculated on a dry weight basis; and a solvent.
  • Embodiment 26 or the slurry of Embodiment 26A, comprising about 5-15 wt% nicotine salt.
  • the aerosol-generating material or slurry of Embodiment 27 comprising about 5-10 wt% nicotine salt.
  • the aerosol-generating material or slurry of any preceding Embodiment comprising about 20-70 wt% gelling agent.
  • the aerosol-generating material or slurry of Embodiment 31 comprising about 20-65 wt% gelling agent.
  • the aerosol-generating material or slurry of Embodiment 31 comprising about 25-70 wt% gelling agent.
  • Embodiment 34 The aerosol-generating material or slurry of Embodiment 33, comprising about 25-65 wt% gelling agent.
  • the aerosol-generating material or slurry of Embodiment 33 comprising about 30-70 wt% gelling agent.
  • Embodiment 36 The aerosol-generating material or slurry of Embodiment 35, comprising about 30-65 wt% gelling agent.
  • Embodiment 37 The aerosol-generating material or slurry of Embodiment 35, comprising about 35-70 wt% gelling agent.
  • Embodiment 38 The aerosol-generating material or slurry of Embodiment 37, comprising about 35-65 wt% gelling agent.
  • Embodiment 39 The aerosol-generating material or slurry of Embodiment 37, comprising about 40-70 wt% gelling agent.
  • Embodiment 40 The aerosol-generating material or slurry of Embodiment 39, comprising about 40-65 wt% gelling agent.
  • the aerosol-generating material or slurry of Embodiment 39 comprising about 45-70 wt% gelling agent.
  • Embodiment 41 The aerosol-generating material or slurry of Embodiment 41, comprising about 40-65 wt% gelling agent.
  • the aerosol-generating material or slurry of any preceding Embodiment comprising about 15-60 wt% aerosol-former material.
  • the aerosol-generating material or slurry of any preceding Embodiment comprising about 15-55 wt% aerosol-former material.
  • the aerosol-generating material or slurry of Embodiment 43 or 43 A comprising about 15-50 wt% aerosol-former material.
  • the aerosol-generating material or slurry of Embodiment 43 comprising about 20-55 wt% aerosol-former material.
  • the aerosol-generating material or slurry of Embodiment 45 comprising about 20-50 wt% aerosol-former material.
  • the aerosol-generating material or slurry of Embodiment 45 comprising about 25-55 wt% aerosol-former material.
  • Embodiment 48 The aerosol-generating material or slurry of Embodiment 47, comprising about 25-50 wt% aerosol-former material.
  • the aerosol-generating material or slurry of Embodiment 47 comprising about 30-55 wt% aerosol-former material.
  • the aerosol-generating material or slurry of Embodiment 49 comprising about 30-50 wt% aerosol-former material.
  • An aerosol-generating material comprising: about 1 to about 30 wt% nicotine salt; about 45 to about 80 wt% gelling agent; about 10 to about 54 wt% aerosol-former material; and optionally filler wherein the wt% values are calculated on a dry weight basis.
  • a slurry comprising: about 1 to about 30 wt% nicotine salt; about 45 to about 80 wt% gelling agent; about 10 to about 54 wt% aerosol-former material; optionally filler wherein the wt% values are calculated on a dry weight basis; and a solvent.
  • Embodiment 51 or the slurry of Embodiment 51 A, comprising about 1-15 wt% nicotine salt.
  • Embodiment 53 The aerosol-generating material or slurry of Embodiment 52, comprising about 1-10 wt% nicotine salt.
  • the aerosol-generating material or slurry of Embodiment 52 comprising about 3-15 wt% nicotine salt.
  • the aerosol-generating material or slurry of Embodiment 54 comprising about 3-10 wt% nicotine salt.
  • Embodiment 56 The aerosol-generating material or slurry of Embodiment 54, comprising about 5-15 wt% nicotine salt.
  • Embodiment 56 The aerosol-generating material or slurry of Embodiment 56, comprising about 5-10 wt% nicotine salt.
  • Embodiment 60 The aerosol-generating material or slurry of Embodiment 60, comprising about 45-65 wt% gelling agent.
  • Embodiment 60 The aerosol-generating material or slurry of Embodiment 60, comprising about 50-70 wt% gelling agent.
  • the aerosol-generating material or slurry of any Embodiment 62 comprising about 50-65 wt% gelling agent.
  • the aerosol-generating material or slurry of Embodiment 64 comprising about 20-50 wt% aerosol-former material.
  • Embodiment 65 The aerosol-generating material or slurry of Embodiment 65, comprising about 25-50 wt% aerosol-former material.
  • Embodiment 67 The aerosol-generating material or slurry of Embodiment 66, comprising about 30-50 wt% aerosol-former material.
  • the gelling agent comprises (or is) one or more compounds selected from polysaccharide gelling agents, such as alginate, pectin, starch or a derivative thereof, cellulose or a derivative thereof, pullulan, carrageenan, agar and agarose; gelatin; gums, such as xanthan gum, guar gum and acacia gum; silica or silicone compounds, such as PDMS and sodium silicate; clays, such as kaolin; and polyvinyl alcohol.
  • polysaccharide gelling agents such as alginate, pectin, starch or a derivative thereof, cellulose or a derivative thereof, pullulan, carrageenan, agar and agarose
  • gelatin such as xanthan gum, guar gum and acacia gum
  • silica or silicone compounds such as PDMS and sodium silicate
  • clays such as kaolin
  • polyvinyl alcohol polyvinyl alcohol
  • Embodiment 72 The aerosol-generating material or slurry of Embodiment 71, wherein the polysaccharide gelling agent is a cellulose derivative.
  • CMC carboxymethylcellulose
  • HPMC hydroxypropyl methylcellulose
  • CA cellulose acetate
  • CAB cellulose acetate butyrate
  • CAP cellulose acetate propionate
  • Embodiment 74 The aerosol-generating material or slurry of Embodiment 73, wherein the cellulose or the derivative thereof, is CMC.
  • Embodiment 77 The aerosol-generating material or slurry of Embodiment 76, wherein alginate is the only gelling agent present in the aerosol-generating material or slurry.
  • the gelling agent comprises (or is) one or more of alginate, pectin, hydroxyethyl cellulose, hydroxypropyl cellulose, carboxymethylcellulose, pullulan, xanthan gum guar gum, carrageenan, agarose, acacia gum, fumed silica, PDMS, sodium silicate, kaolin and polyvinyl alcohol. 79.
  • the aerosol-generating material or slurry of Embodiment 68 wherein the gelling agent comprises (or is) one or more of hydroxyethyl cellulose, hydroxypropyl cellulose, carboxymethylcellulose, guar gum, acacia gum, alginate and/or pectin.
  • the aerosol-generating agent comprises (or is) one or more of glycerol, propylene glycol, diethylene glycol, triethylene glycol, tetraethylene glycol, 1,3-butylene glycol, erythritol, meso-Erythritol, ethyl vanillate, ethyl laurate, a diethyl suberate, triethyl citrate, triacetin, a diacetin mixture, benzyl benzoate, benzyl phenyl acetate, tributyrin, lauryl acetate, lauric acid, myristic acid, and propylene carbonate.
  • the aerosol-generating agent comprises (or is) one or more of glycerol, propylene glycol, diethylene glycol, triethylene glycol, tetraethylene glycol, 1,3-butylene glycol, erythritol, meso-Erythritol, ethy
  • Embodiment 85 The aerosol-generating material or slurry of Embodiment 85, comprising less than about 5 wt% filler.
  • Embodiment 86 The aerosol-generating material or slurry of Embodiment 86, comprising less than about 1 wt% filler.
  • Embodiment 89 The aerosol-generating material or slurry of Embodiment 88, comprising 1 to 5 wt% filler.
  • the aerosol-generating material or slurry of Embodiment 88 comprising 2 to 7 wt% filler.
  • the aerosol-generating material or slurry of any of Embodiments 1 to 84 comprising 3 to 10 wt% filler.
  • Embodiment 91 The aerosol-generating material or slurry of Embodiment 91, comprising 3 to 5 wt% filler.
  • An aerosol-generating composition comprising an aerosol-generating material according to any preceding Embodiment.
  • the aerosol-generating composition of Embodiment 101 further comprising one or more additional active substances and/or flavours, and optionally one or more other functional materials.
  • the aerosol-generating composition of Embodiment 101 or 102 further comprising one or more other functional materials.
  • Embodiment 102 or 103 wherein the other functional materials comprise one or more pH regulators, colouring agents, preservatives, binders, stabilisers, and/or antioxidants.
  • the aerosol-generating composition of any of Embodiments 101 to 104 comprising from about 50-100 wt% (WWB) of the aerosol-generating material.
  • Embodiment 106 The aerosol-generating composition of Embodiment 105, comprising from about 50-90 wt% (WWB) of the aerosol-generating material.
  • Embodiment 105 comprising from about 60-100 wt% (WWB) of the aerosol-generating material.
  • Embodiment 107 The aerosol-generating composition of Embodiment 107, comprising from about 60-95 wt% (WWB) of the aerosol-generating material.
  • Embodiment 109 The aerosol-generating composition of Embodiment 107, comprising from about 70-100 wt% (WWB) of the aerosol-generating material.
  • Embodiment 110 The aerosol-generating composition of Embodiment 109, comprising from about 70-95 wt% (WWB) of the aerosol-generating material.
  • Embodiment 110 comprising from about 70-90 wt% (WWB) of the aerosol-generating material.
  • Embodiment 112B The aerosol-generating composition of Embodiment 112A, wherein the carrier comprises a metal foil.
  • a consumable for use in a non-combustible aerosol provision device comprising the aerosol-generating composition of any of Embodiments 101-112. 113A.
  • Embodiment 113B The consumable of Embodiment 113 to 113 A, wherein the aerosol-generating composition consists of the aerosol-generating material of any of Embodiments 1 to 100.
  • Embodiment 113 to 113B The consumable of Embodiment 113 to 113B, wherein the consumable comprises a single aerosol-generating composition.
  • a non-combustible aerosol provision system comprising the consumable of Embodiment 113 and a non-combustible aerosol provision device.
  • Embodiment 117 or 118 wherein the solvent comprises water.
  • Embodiment 120 The method of Embodiment 117 or 118, wherein the solvent consists essentially of, or consists of water.
  • Embodiments 117 to 120 The method of Embodiments 117 to 120 or the slurry of any of Embodiments 1 to 100, wherein the slurry comprises from about 50 wt%, 60 wt%, 70 wt%, 80 wt% or 90 wt% of solvent (WWB).
  • WWB solvent
  • Exemplary and non-limiting formulation for aerosol-generating material are provided in the table below.

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Preparation (AREA)
  • Manufacture Of Tobacco Products (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP22731405.1A 2021-05-27 2022-05-23 Aerosol generating composition comprising nicotine and acid or nicotine salt Pending EP4346456A1 (en)

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US202163193877P 2021-05-27 2021-05-27
PCT/US2022/030560 WO2022251121A1 (en) 2021-05-27 2022-05-23 Aerosol generating composition comprising nicotine and acid or nicotine salt

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KR (1) KR20240026904A (ko)
CN (1) CN118159148A (ko)
AU (1) AU2022279989A1 (ko)
BR (1) BR112023024834A2 (ko)
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EP3797614B1 (en) 2013-10-29 2023-07-26 Nicoventures Trading Limited Apparatus for heating smokable material
CN107529830B (zh) 2015-02-27 2021-06-29 尼科创业贸易有限公司 用于生成可吸入介质的料筒、部件、以及方法
RU2733625C2 (ru) * 2015-11-24 2020-10-05 Р. Дж. Рейнолдс Тобакко Компани Система подачи аэрозоля с электрическим питанием
WO2020089095A1 (en) * 2018-10-29 2020-05-07 Nerudia Limited Smoking substitute consumable
KR20210149131A (ko) * 2019-04-08 2021-12-08 필립모리스 프로덕츠 에스.에이. 에어로졸 발생 필름을 포함하는 에어로졸 발생 기재
BR112021017857A2 (pt) * 2019-04-08 2021-11-30 Philip Morris Products Sa Sistema gerador de aerossol e artigo gerador de aerossol compreendendo um filme gerador de aerossol
US12011028B2 (en) * 2019-04-08 2024-06-18 Philip Morris Products S.A. Aerosol-generating article comprising an aerosol-generating film
EP3952671B1 (en) * 2019-04-08 2024-06-26 Philip Morris Products S.A. Method of manufacturing an aerosol-generating film
CN111072629A (zh) * 2019-11-22 2020-04-28 云南中烟工业有限责任公司 一种尼古丁-草酸盐复合物晶体及其应用

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KR20240026904A (ko) 2024-02-29
BR112023024834A2 (pt) 2024-02-20
AU2022279989A1 (en) 2023-12-14
CN118159148A (zh) 2024-06-07
IL308843A (en) 2024-01-01
JP2024519173A (ja) 2024-05-08

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