EP4011323A1 - Vorrichtung zur langsamen freisetzung von progesteron - Google Patents

Vorrichtung zur langsamen freisetzung von progesteron Download PDF

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Publication number
EP4011323A1
EP4011323A1 EP20849556.4A EP20849556A EP4011323A1 EP 4011323 A1 EP4011323 A1 EP 4011323A1 EP 20849556 A EP20849556 A EP 20849556A EP 4011323 A1 EP4011323 A1 EP 4011323A1
Authority
EP
European Patent Office
Prior art keywords
flexible extensions
progesterone
tube
eyelets
coupled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20849556.4A
Other languages
English (en)
French (fr)
Other versions
EP4011323A4 (de
Inventor
Osnir Y WATANABE
Adriano ORDOZ BARISSA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wta - Watanabe Tecnologia Aplicada Eirele - Epp
Original Assignee
Wta Watanabe Tecnologia Aplicade Eirele Epp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wta Watanabe Tecnologia Aplicade Eirele Epp filed Critical Wta Watanabe Tecnologia Aplicade Eirele Epp
Publication of EP4011323A1 publication Critical patent/EP4011323A1/de
Publication of EP4011323A4 publication Critical patent/EP4011323A4/de
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D1/00—Surgical instruments for veterinary use
    • A61D1/08—Veterinary obstetrical instruments or devices

Definitions

  • the present utility model refers to a device for slow release of progesterone for veterinary use mainly used for estrus synchronization protocols.
  • Devices for low release of progesterone of veterinary use intended in estrus synchronization comprising a body with material impregnated with progesterone followed by two or more flexible extensions to support the internal walls of the animal vagina.
  • these devices are applied to the animal body with the aid of an applicator tube and a plunger.
  • the device is inserted into this applicator tube, which therefore has a larger diameter than the device itself.
  • the tube is inserted into the animal's vaginal canal to a depth close to the position wherein the device should remain, close to the cervix.
  • a plunger is pressed inside the applicator tube, pushing the device out of the applicator tube.
  • this same tube is used to apply another device for slow release of progesterone to another animal. This is because, due to its dimensions and its resistant material, the cost of the tube is considerable and should not be neglected. However, before its reuse it is necessary to wash and sanitize this tube. This does not, however, guarantee the complete sterilization of the tube, remaining a risk of contamination of other animals. In addition, the washing procedure is laborious and costly.
  • a device for slow release of progesterone which objectives are to allow application to the animal with no need to use a large reusable applicator with a plunger, and with no need to wash the applicator, with less risk of causing injury to the animal, which allows greater precision of application and positioning within the animal body.
  • a device for slow release of progesterone in an animal comprising a body impregnated with progesterone, two flexible extensions extending from one end of the body, and which ends opposite the body curve in spaced apart, each of the two flexible extensions comprising an eyelet in the portion near the ends curving away from each other, the eyelets of the two flexible extensions being axially aligned with each other with the flexible extensions in an extended position; a removable tube coupled to the end of the body opposite the flexible extensions; a cable that passes through the inside of the body and the inside of the tube, with a first end close to the flexible extensions being connected to a pin coupled to the eyelets, and a second free end extending out of the body and tube on the side opposite the flexibles extensions; the pin being coupled to the eyelets aligned with the flexible extensions in the extended position; and the pin being actuated by cable and decoupled from the eyelets, with the flexible extensions being unlocked and in a curved position.
  • the device for slow release of progesterone object of the present utility model, consists of a device for slow release of progesterone in an animal comprising a body 1 at least partially impregnated with progesterone, followed by two flexible extensions 2 extending from one end of the body.
  • a body 1 at least partially impregnated with progesterone
  • two flexible extensions 2 extending from one end of the body.
  • these flexible extensions 2 can be tensioned and extended, being parallel to each other, as illustrated in figure 2 .
  • Each of the two flexible extensions comprises an eyelet 6 in the portion close the ends curving away.
  • the eyelets 6 at both ends are axially aligned with each other when the flexible extensions are in the extended position, so that the two eyelets intersect concentrically when the flexible extensions 2 are extended and aligned with the body 1.
  • the device also comprises a removable tube 3 attached to the end of the body opposite the flexible extensions, as illustrated in figure 3 , and a cable 4 passing through the inside of the body 1, better illustrated in figure 4 .
  • This cable also passes through the inside of the tube 3 at the application time of the device for slow release of progesterone to the animal body, as shown in figure 3 .
  • the removable tube preferably has a diameter smaller than the diameter of the body 1 impregnated with progesterone.
  • the end of the cable 4 close to the flexible extensions is connected to a pin 5 intended to be coupled to the eyelets 6.
  • the opposite end of the cable is a free end extending out of the body 1 and tube 3 on the side opposite the extensions. This free end will be used to pull the device for slow release of progesterone out of the animal body after use.
  • the flexible extensions 2 are tensioned and stretched, with the eyelets 6 aligned.
  • the pin 5 is then coupled inside the two aligned eyelets, as shown in figures 3 and 5 .
  • the flexible extensions 2 are in the tensioned and extended position, parallel to each other, which facilitates the device application inside the vagina of the animal.
  • the device application to the animal body is performed with the flexible extensions 2 tensioned and stretched, introducing the applicator device on the side of the flexible extensions inside the animal vaginal canal, and pushing the device inwards to the ideal depth, for example, close to the cervix, with the aid of the removable tube 3.
  • a part of the handle 4 remains exposed outside the animal vagina even after the device is introduced.
  • the cable is activated, pulling it out of the removable tube 3 until pin 5 is detached from the eyelets 6, unlocking the flexible extensions 2.
  • the flexible extensions 2 are detached, and their extremities tend to return to the curved position away from each other, supporting each other and exerting pressure inside the animal body responsible for fixing the device in the ideal position.
  • the removable tube 3 is detached from the body 1 by pulling it lightly, so that the free end of the handle 4 remains exposed outside the animal vagina. This allows the device to be removed simply after the end of the estrus synchronization procedure, simply by pulling the device out of the animal vagina by the free end of the cable 4.
  • Removable tube 3 is preferably made of disposable, lightweight and low-cost material and cannot be used with other devices for slow release of progesterone, thus reducing the overall cost of the product and the risk of contamination.
  • Body 1 can be made as a single piece with openings, as shown in figures 3 and 4 .
  • the body 1 can be comprised of a support 12 and a detachable piece 11 impregnated with progesterone coupled around the support 12.
  • the removable piece is preferably a cylinder made of polymeric material. Because this part 11 is removable, this allows it to be discarded and replaced with a similar new removable part 11. In this way, the device for slow release of progesterone according to the present model can be easily reused several times, being only necessary to sterilize it and replace the removable part 11 with a new part.
  • This embodiment of the body 1 is particularly advantageous, since the device can be partially reused, cleaning the support 12 with flexible extensions 2 and using a new removable tube 3 and a new removable part 11 impregnated with progesterone.
  • the present utility model reduces this risk, since the application of the device is performed by guiding the device itself inside the vaginal canal with the aid of the removable tube that is also part of the device, therefore, with no need to apply a force of plunger against the animal to release the body with progesterone.
  • the removable tube 3 has dimensions smaller than the progesterone-impregnated body itself, and smaller than the state-of-the-art applicator tubes, which also contributes to reducing the risk of injury.
  • the embodiment of the device according to the present model which is handled and guided directly by the removable tube, being exempt of large tubes and plungers, allows for the person applying the device inside the animal body to have a greater sensitivity in the application, consequently having a better idea of the depth at which the device is being applied, and better precision in its positioning.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Surgical Instruments (AREA)
  • Catching Or Destruction (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
EP20849556.4A 2019-08-08 2020-06-25 Vorrichtung zur langsamen freisetzung von progesteron Pending EP4011323A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BR202019016494-3U BR202019016494U2 (pt) 2019-08-08 2019-08-08 Dispositivo para liberação lenta de progesterona
PCT/BR2020/050227 WO2021022348A1 (pt) 2019-08-08 2020-06-25 Dispositivo para liberação lenta de progesterona

Publications (2)

Publication Number Publication Date
EP4011323A1 true EP4011323A1 (de) 2022-06-15
EP4011323A4 EP4011323A4 (de) 2023-05-03

Family

ID=74502446

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20849556.4A Pending EP4011323A4 (de) 2019-08-08 2020-06-25 Vorrichtung zur langsamen freisetzung von progesteron

Country Status (4)

Country Link
EP (1) EP4011323A4 (de)
BR (1) BR202019016494U2 (de)
MX (1) MX2022001529A (de)
WO (1) WO2021022348A1 (de)

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE35992B1 (en) * 1971-01-22 1976-07-21 Agrophysics Inc Device for insertion into the reproductive tract and metho
US3854476A (en) * 1973-04-05 1974-12-17 R Dickinson Intra-vaginal device and method
FR2536987B1 (fr) * 1982-07-19 1985-10-31 Serimed Sterilet endo-uterin pour les animaux tels que les chiennes
EP0820258B1 (de) * 1995-03-23 2002-10-09 Advanced Animal Technology Limited Substanzabgabevorrichtung
NZ286492A (en) * 1996-05-01 1998-02-26 Dec International Nz Ltd Subst Intra vaginal devices for synchronising oestrus of animals is made up of cured silicone rubber material with 5% by weight of progesterone
NZ500376A (en) * 1997-05-28 2001-01-26 Dec Res Intra-vaginal device for pigs
AU750746B2 (en) * 1998-10-05 2002-07-25 Advanced Animal Technology Limited Improvements in and relating to retention apparatus
BE1012613A3 (fr) * 1999-04-16 2001-01-09 Wildemeersch Dirk Procede de retenue et d'actionnement d'un inserteur de sterilet, et inserteur permettant l'application de ce procede.
BR0205843B1 (pt) * 2001-02-02 2012-12-11 dispositivo intravaginal contendo progesterona, útil como indutor do cio em bovinos produtores de carne e leite, assim como processo para sua fabricação.
CN2525961Y (zh) * 2002-01-18 2002-12-18 西安辰烁生物制品（集团）有限公司 同期发情诱导器
BRPI0802661A2 (pt) * 2008-05-08 2010-01-19 Grascon Do Brasil Ltda Lab dispositivo vaginal para liberaÇço lenta de progesterona (hormânio) utilizado em fÊmeas bovinas
ES2752923T3 (es) * 2009-07-31 2020-04-06 Boehringer Ingelheim Animal Health Usa Inc Cápsulas de liberación prolongada
CN201537164U (zh) * 2009-12-01 2010-08-04 张煦喆 动物立体宫内活性节育器
WO2012021127A2 (en) * 2010-08-10 2012-02-16 Stroud Brad R Method and apparatus to reduce the number of sperm used in artificial insemination of cattle
US10278675B2 (en) * 2014-07-31 2019-05-07 Palo Alto Research Center Incorporated Implantable estrus detection devices, systems, and methods
US9801660B2 (en) * 2014-07-31 2017-10-31 Palo Alto Research Center Incorporated Implantable fluid delivery devices, systems, and methods
BR102015010670B1 (pt) * 2015-05-11 2022-11-08 Wta- Watanabe Tecnologia Aplicada Eirele - Epp Dispositivo de narina para liberação lenta de hormônios e seus usos
BR202016004731Y1 (pt) * 2016-03-02 2020-06-09 Ouro Fino Saude Animal Ltda dispositivo intravaginal com tubo de ativo de progesterona acoplável

Also Published As

Publication number Publication date
MX2022001529A (es) 2022-05-02
EP4011323A4 (de) 2023-05-03
WO2021022348A1 (pt) 2021-02-11
BR202019016494U2 (pt) 2021-02-09

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