EP4006015A4 - METHOD OF SYNTHETICIZING A ZIRCONIUM COMPLEX - Google Patents
METHOD OF SYNTHETICIZING A ZIRCONIUM COMPLEX Download PDFInfo
- Publication number
- EP4006015A4 EP4006015A4 EP20846290.3A EP20846290A EP4006015A4 EP 4006015 A4 EP4006015 A4 EP 4006015A4 EP 20846290 A EP20846290 A EP 20846290A EP 4006015 A4 EP4006015 A4 EP 4006015A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- zirconium complex
- synthesizing zirconium
- synthesizing
- complex
- zirconium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 title 1
- 230000002194 synthesizing effect Effects 0.000 title 1
- 229910052726 zirconium Inorganic materials 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22B—PRODUCTION AND REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
- C22B34/00—Obtaining refractory metals
- C22B34/10—Obtaining titanium, zirconium or hafnium
- C22B34/14—Obtaining zirconium or hafnium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
- C07D255/02—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/003—Compounds containing elements of Groups 4 or 14 of the Periodic Table without C-Metal linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Manufacturing & Machinery (AREA)
- Materials Engineering (AREA)
- Metallurgy (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019139778 | 2019-07-30 | ||
| PCT/JP2020/025031 WO2021019983A1 (ja) | 2019-07-30 | 2020-06-25 | ジルコニウム錯体の合成方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP4006015A1 EP4006015A1 (en) | 2022-06-01 |
| EP4006015A4 true EP4006015A4 (en) | 2023-07-26 |
Family
ID=74228609
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP20846290.3A Pending EP4006015A4 (en) | 2019-07-30 | 2020-06-25 | METHOD OF SYNTHETICIZING A ZIRCONIUM COMPLEX |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220259698A1 (ja) |
| EP (1) | EP4006015A4 (ja) |
| JP (1) | JP7315004B2 (ja) |
| KR (1) | KR20220029691A (ja) |
| CN (1) | CN114206845A (ja) |
| AU (1) | AU2020319963B2 (ja) |
| CA (1) | CA3148952C (ja) |
| WO (1) | WO2021019983A1 (ja) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017161356A1 (en) * | 2016-03-18 | 2017-09-21 | Wake Forest University | Compounds, compositions and associated methods using zirconium-89 in immuno-positron emission tomography |
| WO2019125982A1 (en) * | 2017-12-18 | 2019-06-27 | Janssen Biotech, Inc. | Radiolabeling of polypeptides |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6092320A (ja) | 1983-10-26 | 1985-05-23 | Toyo Tire & Rubber Co Ltd | 高分子量多官能エポキシ樹脂の製造方法 |
| US4933643A (en) | 1989-07-28 | 1990-06-12 | Motorola Inc. | Operational amplifier having improved digitally adjusted null offset |
| US20140147381A1 (en) * | 2012-11-29 | 2014-05-29 | Gregory David Espenan | 89zr compounds, to include somatostatin, apparatus and products comprising such compounds, methods of making same, and methods of using same for radio imaging and/or treatment |
| JP6665806B2 (ja) | 2017-01-31 | 2020-03-13 | Ｊｆｅエンジニアリング株式会社 | ジルコニウムの精製方法および精製装置 |
-
2020
- 2020-06-25 EP EP20846290.3A patent/EP4006015A4/en active Pending
- 2020-06-25 AU AU2020319963A patent/AU2020319963B2/en active Active
- 2020-06-25 US US17/630,472 patent/US20220259698A1/en active Pending
- 2020-06-25 JP JP2021536845A patent/JP7315004B2/ja active Active
- 2020-06-25 CA CA3148952A patent/CA3148952C/en active Active
- 2020-06-25 KR KR1020227002751A patent/KR20220029691A/ko active Search and Examination
- 2020-06-25 CN CN202080054593.3A patent/CN114206845A/zh active Pending
- 2020-06-25 WO PCT/JP2020/025031 patent/WO2021019983A1/ja unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017161356A1 (en) * | 2016-03-18 | 2017-09-21 | Wake Forest University | Compounds, compositions and associated methods using zirconium-89 in immuno-positron emission tomography |
| WO2019125982A1 (en) * | 2017-12-18 | 2019-06-27 | Janssen Biotech, Inc. | Radiolabeling of polypeptides |
Non-Patent Citations (2)
| Title |
|---|
| GRAVES STEPHEN A ET AL: "Evaluation of a chloride-based89Zr isolation strategy using a tributyl phosphate (TBP)-functionalized extraction resin", NUCLEAR MEDICINE AND BIOLOGY, ELSEVIER, NY, US, vol. 64, 18 June 2018 (2018-06-18), pages 1 - 7, XP085493278, ISSN: 0969-8051, DOI: 10.1016/J.NUCMEDBIO.2018.06.003 * |
| See also references of WO2021019983A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4006015A1 (en) | 2022-06-01 |
| KR20220029691A (ko) | 2022-03-08 |
| US20220259698A1 (en) | 2022-08-18 |
| JPWO2021019983A1 (ja) | 2021-02-04 |
| AU2020319963B2 (en) | 2023-04-27 |
| AU2020319963A1 (en) | 2022-02-24 |
| WO2021019983A1 (ja) | 2021-02-04 |
| JP7315004B2 (ja) | 2023-07-26 |
| CA3148952C (en) | 2024-01-16 |
| CA3148952A1 (en) | 2021-02-04 |
| CN114206845A (zh) | 2022-03-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
| 17P | Request for examination filed |
Effective date: 20220118 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
| DAV | Request for validation of the european patent (deleted) | ||
| DAX | Request for extension of the european patent (deleted) | ||
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20230628 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 51/04 20060101ALI20230622BHEP Ipc: C07D 487/04 20060101ALI20230622BHEP Ipc: C22B 3/26 20060101ALI20230622BHEP Ipc: C07F 7/00 20060101ALI20230622BHEP Ipc: C22B 34/14 20060101ALI20230622BHEP Ipc: C07D 403/12 20060101ALI20230622BHEP Ipc: C07D 403/06 20060101ALI20230622BHEP Ipc: C07D 257/02 20060101ALI20230622BHEP Ipc: C07D 255/02 20060101AFI20230622BHEP |