EP3993878A4 - Beta-adrenerger agonist und verfahren zu seiner verwendung - Google Patents

Beta-adrenerger agonist und verfahren zu seiner verwendung Download PDF

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Publication number
EP3993878A4
EP3993878A4 EP20835619.6A EP20835619A EP3993878A4 EP 3993878 A4 EP3993878 A4 EP 3993878A4 EP 20835619 A EP20835619 A EP 20835619A EP 3993878 A4 EP3993878 A4 EP 3993878A4
Authority
EP
European Patent Office
Prior art keywords
methods
same
adrenergic agonist
beta adrenergic
beta
Prior art date
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Pending
Application number
EP20835619.6A
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English (en)
French (fr)
Other versions
EP3993878A1 (de
Inventor
Anthony P. FORD
Jiaxin Yu
David Scott Carter
Wei Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Curasen Therapeutics Inc
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Curasen Therapeutics Inc
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Filing date
Publication date
Priority claimed from US16/831,285 external-priority patent/US11040944B2/en
Application filed by Curasen Therapeutics Inc filed Critical Curasen Therapeutics Inc
Publication of EP3993878A1 publication Critical patent/EP3993878A1/de
Publication of EP3993878A4 publication Critical patent/EP3993878A4/de
Pending legal-status Critical Current

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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
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    • A61K31/37—Coumarins, e.g. psoralen
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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    • C07D277/62—Benzothiazoles
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EP20835619.6A 2019-07-01 2020-06-30 Beta-adrenerger agonist und verfahren zu seiner verwendung Pending EP3993878A4 (de)

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US201962934482P 2019-11-12 2019-11-12
US16/831,285 US11040944B2 (en) 2019-03-27 2020-03-26 Beta adrenergic agonist and methods of using the same
US16/831,370 US10947196B2 (en) 2019-03-27 2020-03-26 Beta adrenergic agonist and methods of using the same
US202063018431P 2020-04-30 2020-04-30
PCT/US2020/040308 WO2021003161A1 (en) 2019-07-01 2020-06-30 Beta adrenergic agonist and methods of using the same

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GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
JP2022527769A (ja) * 2019-03-27 2022-06-06 キュラセン セラピューティクス インコーポレイテッド ベータアドレナリンアゴニスト及びそれを使用する方法
GB202015035D0 (en) 2020-09-23 2020-11-04 Atrogi Ab New compounds and methods
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CN115710158A (zh) * 2021-08-23 2023-02-24 凯特立斯（深圳）科技有限公司 一种不对称催化制备替格瑞洛中间体的方法
GB202113594D0 (en) 2021-09-23 2021-11-10 Atrogi Ab New compounds and methods
JP2024536815A (ja) * 2021-09-23 2024-10-08 キュラセン セラピューティクス インコーポレイテッド β－アドレナリンアゴニスト及びその使用方法
GB202113588D0 (en) 2021-09-23 2021-11-10 Atrogi Ab New compounds and methods
CN115677577A (zh) * 2021-11-03 2023-02-03 中国药科大学 靶向srsf6蛋白的小分子化合物及其制备方法和用途
GB202204085D0 (en) 2022-03-23 2022-05-04 Atrogi Ab New compounds and methods
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses
CN115521254B (zh) * 2022-09-27 2024-05-31 中国药科大学 一种茚达特罗衍生物及其制备方法和应用
WO2024153813A1 (en) 2023-01-20 2024-07-25 Atrogi Ab Beta 2-adrenergic receptor agonists for treatment or prevention of muscle wasting
GB202302225D0 (en) 2023-02-16 2023-04-05 Atrogi Ab New medical uses
GB202303229D0 (en) 2023-03-06 2023-04-19 Atrogi Ab New medical uses
GB202304604D0 (en) 2023-03-29 2023-05-10 Atrogi Ab New compounds and medical uses thereof
GB202304661D0 (en) 2023-03-29 2023-05-10 Atrogi Ab New compounds and medical uses thereof
GB202304652D0 (en) 2023-03-29 2023-05-10 Atrogi Ab New compounds and medical uses thereof
WO2024200780A1 (en) 2023-03-29 2024-10-03 Atrogi Ab Heterocycloalkyl beta-hydroxy alkyl amines for use in the treatment of hyperglycaemia and disorders characterised by hyperglycaemia

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