EP3962546A4 - BIOCOMPATIBLE, BIODEGRADABLE AND BIORESORBABLE HYALURONIC ACID/CHITOSAN/CARBOXYMETHYLCELLULOSE ADHESIVE MEMBRANE AND MANUFACTURING PROCESS - Google Patents

BIOCOMPATIBLE, BIODEGRADABLE AND BIORESORBABLE HYALURONIC ACID/CHITOSAN/CARBOXYMETHYLCELLULOSE ADHESIVE MEMBRANE AND MANUFACTURING PROCESS Download PDF

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Publication number
EP3962546A4
EP3962546A4 EP20801738.4A EP20801738A EP3962546A4 EP 3962546 A4 EP3962546 A4 EP 3962546A4 EP 20801738 A EP20801738 A EP 20801738A EP 3962546 A4 EP3962546 A4 EP 3962546A4
Authority
EP
European Patent Office
Prior art keywords
chitosan
biocompatible
biodegradable
production method
hyaluronic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20801738.4A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP3962546A1 (en
Inventor
Faruk OYTUN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VSY Biyoteknoloji ve Ilac Sanayi AS
Original Assignee
VSY Biyoteknoloji ve Ilac Sanayi AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by VSY Biyoteknoloji ve Ilac Sanayi AS filed Critical VSY Biyoteknoloji ve Ilac Sanayi AS
Publication of EP3962546A1 publication Critical patent/EP3962546A1/en
Publication of EP3962546A4 publication Critical patent/EP3962546A4/en
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08—Cellulose derivatives
    • C08L1/26—Cellulose ethers
    • C08L1/28—Alkyl ethers
    • C08L1/286—Alkyl ethers substituted with acid radicals, e.g. carboxymethyl cellulose [CMC]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/041—Mixtures of macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B15/00—Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
    • C08B15/005—Crosslinking of cellulose derivatives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
EP20801738.4A 2019-05-03 2020-04-30 BIOCOMPATIBLE, BIODEGRADABLE AND BIORESORBABLE HYALURONIC ACID/CHITOSAN/CARBOXYMETHYLCELLULOSE ADHESIVE MEMBRANE AND MANUFACTURING PROCESS Pending EP3962546A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2019/06601A TR201906601A2 (ko) 2019-05-03 2019-05-03
PCT/TR2020/050358 WO2020226587A1 (en) 2019-05-03 2020-04-30 A biocompatible, biodegradable and bioresorbable adhesion membrane including hyaluronic acid / chitosan / carboxymethyl cellulose and production method

Publications (2)

Publication Number Publication Date
EP3962546A1 EP3962546A1 (en) 2022-03-09
EP3962546A4 true EP3962546A4 (en) 2023-01-04

Family

ID=73051597

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20801738.4A Pending EP3962546A4 (en) 2019-05-03 2020-04-30 BIOCOMPATIBLE, BIODEGRADABLE AND BIORESORBABLE HYALURONIC ACID/CHITOSAN/CARBOXYMETHYLCELLULOSE ADHESIVE MEMBRANE AND MANUFACTURING PROCESS

Country Status (3)

Country Link
EP (1) EP3962546A4 (ko)
TR (1) TR201906601A2 (ko)
WO (1) WO2020226587A1 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111234289B (zh) * 2020-02-11 2022-04-01 南通大学 一种防粘连聚甲醛结扎止血夹及其制备方法与应用
CN112826975B (zh) * 2021-01-29 2022-04-15 欣乐加生物科技温州有限公司 一种医用壳聚糖快速止血敷料及制备方法
JP2024506405A (ja) * 2021-02-16 2024-02-13 コーネル ユニヴァーシティー 多糖－グリセリン耐貫通性組成物およびそれから作製された外科用バリア
CN112813007A (zh) * 2021-02-23 2021-05-18 江苏科技大学 一种生物模板法修复生物材料膜的方法
CN114921401B (zh) * 2022-05-24 2023-07-18 灵知蓝诺(北京)生物技术有限公司 一种基于液相分子筛从粘液中提取细胞的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4619995A (en) * 1984-12-24 1986-10-28 Nova Chem Limited N,O-carboxymethyl chitosan and preparative method therefor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100252704B1 (ko) * 1998-02-16 2000-04-15 김갑종 고순도 결정성 nocc의 제조방법 및 효소를 이용한 수용성키토산의 분자량 조절방법
CN1220528C (zh) * 2003-08-19 2005-09-28 大连永兴医用材料有限公司 羧甲基壳聚糖/羧甲基纤维素防手术粘连膜及其制备方法
KR100588614B1 (ko) * 2003-11-10 2006-06-13 주식회사 바이오레인 기포를 포함하는 유착방지제
CN106975098B (zh) * 2017-04-13 2020-07-07 赛克赛斯生物科技股份有限公司 一种复合多糖止血组合物及其制备方法与应用
KR101923734B1 (ko) * 2017-04-13 2018-11-29 영남대학교 산학협력단 유착 방지용 가교 필름
CN107417801B (zh) * 2017-06-20 2020-11-24 中国人民解放军东部战区总医院 一种可注射水凝胶及其制备方法与应用

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4619995A (en) * 1984-12-24 1986-10-28 Nova Chem Limited N,O-carboxymethyl chitosan and preparative method therefor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ZHAO XI HONG ET AL: "Preparation and Properties of Sodium Carboxymethyl Cellulose-Hyaluronic Acid-Carboxymethyl Chitosan Blend", APPLIED MECHANICS AND MATERIALS, vol. 20-23, 1 January 2010 (2010-01-01), pages 1157 - 1161, XP055983012, DOI: 10.4028/www.scientific.net/AMM.20-23.1157 *

Also Published As

Publication number Publication date
EP3962546A1 (en) 2022-03-09
TR201906601A2 (ko) 2020-11-23
WO2020226587A1 (en) 2020-11-12

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