EP3962546A4 - A biocompatible, biodegradable and bioresorbable adhesion membrane including hyaluronic acid / chitosan / carboxymethyl cellulose and production method - Google Patents

A biocompatible, biodegradable and bioresorbable adhesion membrane including hyaluronic acid / chitosan / carboxymethyl cellulose and production method Download PDF

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Publication number
EP3962546A4
EP3962546A4 EP20801738.4A EP20801738A EP3962546A4 EP 3962546 A4 EP3962546 A4 EP 3962546A4 EP 20801738 A EP20801738 A EP 20801738A EP 3962546 A4 EP3962546 A4 EP 3962546A4
Authority
EP
European Patent Office
Prior art keywords
chitosan
biocompatible
biodegradable
production method
hyaluronic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20801738.4A
Other languages
German (de)
French (fr)
Other versions
EP3962546A1 (en
Inventor
Faruk OYTUN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VSY Biyoteknoloji ve Ilac Sanayi AS
Original Assignee
VSY Biyoteknoloji ve Ilac Sanayi AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by VSY Biyoteknoloji ve Ilac Sanayi AS filed Critical VSY Biyoteknoloji ve Ilac Sanayi AS
Publication of EP3962546A1 publication Critical patent/EP3962546A1/en
Publication of EP3962546A4 publication Critical patent/EP3962546A4/en
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08—Cellulose derivatives
    • C08L1/26—Cellulose ethers
    • C08L1/28—Alkyl ethers
    • C08L1/286—Alkyl ethers substituted with acid radicals, e.g. carboxymethyl cellulose [CMC]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/041—Mixtures of macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B15/00—Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
    • C08B15/005—Crosslinking of cellulose derivatives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
EP20801738.4A 2019-05-03 2020-04-30 A biocompatible, biodegradable and bioresorbable adhesion membrane including hyaluronic acid / chitosan / carboxymethyl cellulose and production method Pending EP3962546A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2019/06601A TR201906601A2 (en) 2019-05-03 2019-05-03
PCT/TR2020/050358 WO2020226587A1 (en) 2019-05-03 2020-04-30 A biocompatible, biodegradable and bioresorbable adhesion membrane including hyaluronic acid / chitosan / carboxymethyl cellulose and production method

Publications (2)

Publication Number Publication Date
EP3962546A1 EP3962546A1 (en) 2022-03-09
EP3962546A4 true EP3962546A4 (en) 2023-01-04

Family

ID=73051597

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20801738.4A Pending EP3962546A4 (en) 2019-05-03 2020-04-30 A biocompatible, biodegradable and bioresorbable adhesion membrane including hyaluronic acid / chitosan / carboxymethyl cellulose and production method

Country Status (3)

Country Link
EP (1) EP3962546A4 (en)
TR (1) TR201906601A2 (en)
WO (1) WO2020226587A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111234289B (en) * 2020-02-11 2022-04-01 南通大学 Anti-adhesion polyformaldehyde ligation hemostatic clamp and preparation method and application thereof
CN112826975B (en) * 2021-01-29 2022-04-15 欣乐加生物科技温州有限公司 Medical chitosan rapid hemostatic dressing and preparation method thereof
CN117320763A (en) * 2021-02-16 2023-12-29 康奈尔大学 Polysaccharide-glycerol penetration resistant compositions and surgical barriers made therefrom
CN112813007A (en) * 2021-02-23 2021-05-18 江苏科技大学 Method for repairing biological material film by biological template method
KR102388509B1 (en) * 2021-06-14 2022-04-20 (주)씨앤엘디 Film type anti-adhesion composition with excellent mucosal adhesion and swelling properties
CN114921401B (en) * 2022-05-24 2023-07-18 灵知蓝诺(北京)生物技术有限公司 Method for extracting cells from mucus based on liquid phase molecular sieve

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4619995A (en) * 1984-12-24 1986-10-28 Nova Chem Limited N,O-carboxymethyl chitosan and preparative method therefor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100252704B1 (en) * 1998-02-16 2000-04-15 김갑종 Method of making n,o-carboxy methyl chitosan with high purity crystallization and a method of controlling a molecular weight of water-soluble chitosan
CN1220528C (en) * 2003-08-19 2005-09-28 大连永兴医用材料有限公司 Carboxymethyl chitosan / carboxymethyl cellulose operative antiblocking film and method for making the same
KR100588614B1 (en) * 2003-11-10 2006-06-13 주식회사 바이오레인 Anti-adhesion agent with gas bubble
CN106975098B (en) * 2017-04-13 2020-07-07 赛克赛斯生物科技股份有限公司 Composite polysaccharide hemostatic composition and preparation method and application thereof
KR101923734B1 (en) * 2017-04-13 2018-11-29 영남대학교 산학협력단 A crosslinked film for adhesion prevention
CN107417801B (en) * 2017-06-20 2020-11-24 中国人民解放军东部战区总医院 Injectable hydrogel and preparation method and application thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4619995A (en) * 1984-12-24 1986-10-28 Nova Chem Limited N,O-carboxymethyl chitosan and preparative method therefor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ZHAO XI HONG ET AL: "Preparation and Properties of Sodium Carboxymethyl Cellulose-Hyaluronic Acid-Carboxymethyl Chitosan Blend", APPLIED MECHANICS AND MATERIALS, vol. 20-23, 1 January 2010 (2010-01-01), pages 1157 - 1161, XP055983012, DOI: 10.4028/www.scientific.net/AMM.20-23.1157 *

Also Published As

Publication number Publication date
WO2020226587A1 (en) 2020-11-12
EP3962546A1 (en) 2022-03-09
TR201906601A2 (en) 2020-11-23

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