EP3932532A1 - Appareil de mélange, installation de mélange et procédé de mélange de substances dans des récipients fermés - Google Patents

Appareil de mélange, installation de mélange et procédé de mélange de substances dans des récipients fermés Download PDF

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Publication number
EP3932532A1
EP3932532A1 EP21191494.0A EP21191494A EP3932532A1 EP 3932532 A1 EP3932532 A1 EP 3932532A1 EP 21191494 A EP21191494 A EP 21191494A EP 3932532 A1 EP3932532 A1 EP 3932532A1
Authority
EP
European Patent Office
Prior art keywords
receptacles
holder
mixing apparatus
containers
mixing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21191494.0A
Other languages
German (de)
English (en)
Inventor
Larry STIVER
Vincent AHLHEIT
Peter SIESEL
Dominic Erb
Klaus LUN
Christoph KARTHAUS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tecan Trading AG
Original Assignee
Tecan Trading AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tecan Trading AG filed Critical Tecan Trading AG
Priority to EP21191494.0A priority Critical patent/EP3932532A1/fr
Publication of EP3932532A1 publication Critical patent/EP3932532A1/fr
Pending legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20—Mixing the contents of independent containers, e.g. test tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20—Mixing the contents of independent containers, e.g. test tubes
    • B01F31/23—Mixing the contents of independent containers, e.g. test tubes by pivoting the containers about an axis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20—Mixing the contents of independent containers, e.g. test tubes
    • B01F31/201—Holders therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/22—Control or regulation
    • B01F35/221—Control or regulation of operational parameters, e.g. level of material in the mixer, temperature or pressure
    • B01F35/2214—Speed during the operation
    • B01F35/22142—Speed of the mixing device during the operation
    • B01F35/221422—Speed of rotation of the mixing axis, stirrer or receptacle during the operation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32—Driving arrangements
    • B01F35/325—Driving reciprocating or oscillating stirrers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/40—Mounting or supporting mixing devices or receptacles; Clamping or holding arrangements therefor
    • B01F35/42—Clamping or holding arrangements for mounting receptacles on mixing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials

Definitions

  • the present invention relates to a mixing apparatus, in particular for mixing substances in closed containers.
  • swivel table which can be swiveled by means of a drive.
  • the swivel table comprises individual specific holders for ampoules with different diameters or the swivel table comprises a pattern of fingers which protrude from the table top and between which different ampoules can be arranged, with smaller ampoules rolling back and forth between the fingers when swiveled.
  • a holder for ampoules is rotatably mounted on two sides, the holder being pivotable by means of a drive.
  • An ampoule can be used in each container receptacle of the holder.
  • An object of the present invention is to provide a mixing apparatus in which the risk of mix-ups is reduced and in which the insertion and removal of the containers which contain substances to be mixed is made easier.
  • a mixing apparatus comprises a drive unit with a drive and with a shaft which can be pivoted about a pivot axis and which is operatively connected to the drive, a pivot mount which is arranged on the shaft, the pivot axis being oriented essentially horizontally, the pivot mount comprising a base, on which receptacles are provided which extend away from the base and into which holders for containers can be inserted.
  • the drive unit comprises a housing in which an electro-mechanical drive, with or without a gearbox, is arranged.
  • the base can be designed as a plate or as a frame.
  • the swivel mount can be swiveled about the swivel axis by any angle in both directions. That is to say, the swivel mount can be swiveled back and forth through any desired angle by means of the drive unit, or the swivel mount can be rotated once or several times around the swivel axis in one of the two directions of rotation.
  • Powders or fluids such as suspensions or emulsions, can therefore be mixed.
  • whole blood i.e. blood plasma or blood serum
  • the substances to be mixed can be filled into test tubes or ampoules.
  • Piercing ampoules comprise glass or plastic containers which are closed at the top with a lid which comprises a septum.
  • the septum comprises a soft plastic, for example made of PTFE or silicone, which can be pierced with a pipette needle or tip.
  • a lid can be screwed onto the open-topped container with a thread.
  • the mixing apparatus comprises a control unit with which the swivel angle, the swivel speed and the swivel direction can be set are. With the setting of these values, an optimal mixture of the substances can be achieved.
  • the receptacles comprise first receptacles, which are arranged in a region of the base near the shaft, and second receptacles, which are arranged in a region of the base remote from the shaft.
  • the holders can be inserted with a first end in the first receptacle and with a second end in the second receptacle.
  • the position and orientation of each holder is clearly and reliably determined.
  • the additional receptacles give the holders additional support or they allow the introduction of shorter holders which do not extend over the entire length of the swivel receptacle.
  • the receptacles comprise elevations which can protrude into complementary recesses in the ends of the holders.
  • the elevations are elements which extend directly from the base of the pivot mount.
  • the elevations can be pins, for example pins with a circular cross-section. However, other cross-sections are also conceivable.
  • the elevations can also be slot nuts, for example for T-slots or dovetail slots.
  • the receptacles can also include recesses into which complementary elevations of the ends of the holders can protrude, and which also form a pin-hole connection or a slot nut-groove connection.
  • receptacles are arranged next to one another in a direction transverse to the pivot axis.
  • several identical or different holders can be inserted next to one another into the swivel mount, so that the contents of several containers can be mixed at the same time.
  • the receptacles are arranged symmetrically with respect to the pivot axis.
  • the mixing apparatus comprises first spacers which can be inserted into the receptacles and into which the holders for the containers can be inserted, and second spacers which are arranged between the receptacles and on which the holders for the containers can rest.
  • first spacers which can be inserted into the receptacles and into which the holders for the containers can be inserted
  • second spacers which are arranged between the receptacles and on which the holders for the containers can rest.
  • third receptacles are provided on the swivel receptacle on the side of the receptacles, with which a retaining element can be arranged fixedly or removably at least in the area between the receptacles at a distance from the base.
  • the third receptacles are designed in such a way that the retaining element can be detachably or displaceably arranged therein. Accordingly, a releasable holding element can be provided or a displacement element can be provided with which the retaining element can be displaced or pivoted in a plane.
  • the mixing apparatus comprises a bearing unit which lies opposite the drive unit with respect to the swivel mount and in which the swivel mount is pivotably mounted in alignment with the shaft. Due to the bearing on both sides of the swivel mount, the corresponding bearings and the swivel mount have to be of stable dimensions, so that they require less space and so that less mass has to be moved.
  • the mixing apparatus comprises at least one holder for containers, which can be inserted into the receptacles.
  • each holder comprises a plurality of container receptacles which are arranged along a longitudinal axis and are formed between the two ends.
  • the container receptacles can, for example, be countersunk holes with a circular cross-section. Other cross sections are however also possible.
  • Each container receptacle can comprise at least one lateral opening which extends laterally outward from the respective container receptacle transversely to the longitudinal axis. The at least one opening can be a slot or a window.
  • Each container receptacle can comprise two lateral openings which are arranged opposite one another with respect to the longitudinal axis and which together with the container receptacle form a passage in the holder.
  • Each container receptacle can accordingly be assigned a slot and a window, two slots or two windows.
  • a clamping strap can be provided which protrudes through the window into the respective container receptacle, whereby a container received therein can be clamped therein.
  • a bracket plate can be arranged on the holder, which plate includes all of the clamping brackets.
  • the mixing apparatus comprises at least one retaining element which is arranged in the third receptacles.
  • the retaining element comprises a perforated plate, the holes being arranged in such a way that they are aligned with the container receptacles formed in the holder, the internal dimensions of the holes being smaller than the internal dimensions of the container receptacles.
  • the mentioned embodiments of the mixer can be used in any combination provided they do not contradict one another.
  • a mixing plant according to the invention comprises a machine frame on which a mixing apparatus according to the invention is arranged.
  • the mixing system can comprise a work surface which is arranged on the machine stand and wherein the mixing apparatus is arranged on the work surface.
  • the mixing system comprises a pipetting unit with which fluids can be supplied to or removed from containers located in the mixing apparatus.
  • the pipetting unit comprises a transport unit on which pipette tips are arranged and with which the pipette tips can be moved horizontally and / or vertically in an area above the machine stand or above the work surface.
  • the mixing system comprises a reading unit with which markings from the containers to be picked up by the mixing apparatus can be read.
  • the markings can be selected from the group which includes 1D barcode, 2D barcode, RFID tag and the like.
  • the mentioned embodiments of the mixing plant can be used in any combination provided they do not contradict one another.
  • the introduction can be a start, for example when the swivel mount comprises cylindrical pins and the holder is provided with correspondingly complementary bores.
  • the introduction can also be a pushing in, for example if the swivel mount comprises sliding blocks and the holder is provided with a correspondingly complementary groove.
  • fastening elements can be removed which fix the retaining element in the corresponding receptacles and the retaining element can then be lifted off and stored at a different location independently of the mixer.
  • the retaining element can be pushed linearly away from the area above the pivot mount by means of a displacement mechanism.
  • this can be Retaining element can be pivoted away from the area above the pivot mount in a plane by means of a rotation mechanism. If the retaining element is arranged fixedly on the swivel mount, then the holder must be pushed into the swivel mount under the retaining element, for example along the swivel axis.
  • the contents of a mother tube which contains whole blood, for example, can be mixed alone or with additional substances.
  • a portion of the whole blood can be re-pipetted from the mother tube to a daughter tube.
  • the daughter tube can be empty beforehand or can contain a substance such as a reagent.
  • the contents of the daughter pipe can then be mixed again.
  • the holder with the containers arranged therein can be removed from the mixing apparatus and fed to an analysis device.
  • the Figure 1 shows a perspective view of a first embodiment of a mixing apparatus according to the invention.
  • the mixing apparatus comprises a drive unit 1, with a drive 10, which is operatively connected to a rotatable shaft 11 and can pivot or rotate this about a pivot axis A.
  • the pivot axis A is oriented essentially horizontally.
  • a swivel mount 2 is operatively connected to the shaft 11 and can thus be swiveled about the swivel axis A by the drive 10.
  • the swivel mount includes a base plate 20, which includes first mounts 21 in an area near the shaft and which includes second mounts 22 in an area remote from the shaft.
  • a holder 3 can be removably arranged in a first receptacle 21 and in a second receptacle 22 aligned therewith in the direction of the pivot axis.
  • Containers 7 can be accommodated in the holder 3.
  • the holder comprises lateral slots 320 through which markings on the containers 7 can be seen.
  • the mixing apparatus comprises a bearing unit 5, which is arranged on the side of the swivel mount 2 which is opposite the drive unit 1.
  • the pivot mount 2 is mounted in the bearing unit 5 so as to be pivotable about the pivot axis A.
  • the bearing unit 5 is connected and aligned with the drive unit 1 via a connecting plate 6.
  • a retaining element 4 is removably arranged in third receptacles 25 above the holders 3 and the containers 7 received therein.
  • the distance between the retaining element 4 and the holders 3 is dimensioned in such a way that the surface of the retaining element 4 facing the holder 3 essentially rests against the free ends of the containers 7 accommodated in the holder 3 or is a few millimeters apart, for example 1 to 5 Millimeter. Also shown is a pipetting unit 81 with a transport unit 810 and pipette tips 811, the transport unit 810 having aligned the pipette tips 811 with the containers 7 and lowering the pipette tips 811 so that they protrude into the interior of the containers 7.
  • the Figure 2 shows the mixer of the Figure 1 , without inserted holder and without retaining element.
  • the first receptacles 21 and the second receptacles 22 comprise a low area and a raised area, the low area being at a smaller distance from the base plate 20 and the raised area being at a greater distance from the base plate 20.
  • first spacers 23 can be provided, which are placed on the lower areas and increase the distance from the base plate 20.
  • the first and second receptacles 21, 22 and the first spacers 23 include elevations 210, 220 in the form of cylindrical pins.
  • Second spacers 24 are provided on the base plate 20, which spacers are arranged essentially evenly distributed between the first receptacles 21 and the second receptacles 22 of the raised areas.
  • a third receptacle 25 in the form of a cylinder pin is arranged in each case.
  • the distance between the holders 3 and the base plate 20 is greater by the thickness of the third spacers 23 than in the rest of the area.
  • the Figure 3 shows the mixer of the Figure 2 with inserted holders 3, in which containers 7.70 are used.
  • the longer containers 7 are arranged with their holders 3 in the receptacles without first spacers 23 and the shorter containers 70 are with the same holders 3 in the Spacers 23 arranged.
  • the first spacers 23 are coordinated with the shorter containers 7 and the longer containers 70 in such a way that the tops of all containers 7, 70 are aligned with one another.
  • the Figure 4 shows a perspective view of a holder 3 for containers 7 that can be used in the inventive mixing apparatus.
  • the holder 3 extends essentially along a longitudinal axis L and comprises a first end 30 and a second end 31 opposite the latter, with which each holder 3 can be inserted into the first, respectively second recordings 21,22 of the swivel mount 2 can be used.
  • the two ends 30, 31 are designed as tabs which extend laterally outward along the longitudinal axis L from the upper surface of the holder 3.
  • the two ends 30,31 each include a recess 300,310 in the form of a through hole with a circular cross-section.
  • Container receptacles 32 in the form of cylindrical bores are formed in the holder 3 along the longitudinal axis L and extend from the upper side of the holder downwards over part of the height of the holder 3.
  • Each container receptacle 32 comprises a slot 320 and a window 321, both of which extend laterally outward from the container receptacle 32, transversely to the longitudinal axis L, the window 321 being arranged on the side of the container receptacle 32 which is opposite the slot.
  • a tab plate 323 On the side of the holder 3, which which includes window 321, a tab plate 323 is arranged which includes clamping tabs 322 which each protrude through a window 321 into the interior of the container receptacle. With the clamping tabs 322, the containers 7 received in the holder 3 can be clamped laterally in the container receptacles 32 so that they cannot fall out of the holder when it is turned upside down.
  • the Figure 5 shows a sketched perspective representation of a second embodiment of a mixing apparatus according to the invention.
  • the connecting plate 6 comprises a recess 60 between the drive unit 1 and the bearing unit 5.
  • the swivel mount 2 is arranged and supported between the drive unit 1 and the bearing unit 5 in such a way that the surface of the base plate 20 is essentially flush with the surface of the connecting plate 6 is aligned.
  • the swivel mount 2 can be freely swiveled in the recess 60 in the connecting plate 6 with the drive unit 1.
  • the connecting plate is arranged directly on a machine stand 8.
  • the elevations 210, 220 of the first and second receptacles 21, 22 of the pivot receptacle 2 are designed as slot nuts which extend away from the base plate 20.
  • the sliding blocks are aligned with one another with respect to the pivot axis A and are arranged in rows next to one another transversely to the pivot axis A.
  • Third receptacles 25, with which the retaining element 4 is fixedly connected to the base plate 20, are arranged on the base plate 20.
  • the retaining element 4 in turn comprises holes.
  • In this illustration is on the connecting plate 6, on the side A reading unit 82 is arranged on the storage unit 5 and the storage unit comprises a recess 50, which allows the reading unit 82 to recognize and read in markings on both sides of the storage unit 5.
  • the containers 7 can be inserted into the holder 3 at any position. However, it must be ensured that the markings on the containers 7 are aligned in such a way that they can be read by the reading unit 82 when the holder 3 is inserted or pushed into the swivel mount 2. Thus each container can be identified and at the same time the position of each container 7 in the holder 3 can be determined.
  • a pipetting unit 81 with a transport unit 810 and with pipette tips 811 is also partially shown, the pipette tips 811 being movable by means of the transport unit 810 in the space at least above the mixing apparatus. This arrangement allows fluids to be added or removed from the containers 7 accommodated in the mixing device. Accordingly, fluids can also be pipetted before or after mixing in the mixing device.
  • the Figure 6 shows a sketched perspective representation of a third embodiment of a mixing apparatus according to the invention.
  • This embodiment does not include a bearing unit 5. Accordingly, no connecting plate 6 is required.
  • the drive unit 1 and the reading unit 82 are arranged on a work surface 80 which is arranged on the machine stand 8.
  • Receiving elements 800 are provided on the work surface 80, which in this embodiment are identical to the elevations 210, 220 and with which the drive unit 1 and the reading unit 82 are arranged, aligned and releasably fastened on the work surface 80.
  • the swivel mount 2 is only supported on the side of the shaft 11, that is to say on the side of the drive unit 1.
  • the side of the swivel mount 2 which is opposite the drive unit 2 is freely floating. With such an arrangement, the holders 3 with the containers 7 received therein can be pushed into the swivel mount 2 unhindered and at any position. The detection of the container 7 and its position in the holder 3 can, in turn, take place when it is pushed in, as a result of which the process reliability is significantly increased.
  • FIG. 4 shows a sketched perspective illustration of a holder 3 which can be pushed into the mixing apparatus of the second or third embodiment.
  • the holder 3 essentially corresponds to that of FIG Figure 4 , ie it extends along the longitudinal axis L, has container receptacles 32 which comprise a slot 320 and a window 321 and has clamping lugs 322 which are formed together in one piece with the tab plate 323 and which protrude through the window 321 into the interior of the container receptacles 32 .
  • the holder 3 comprises a groove 33 which is arranged on the underside of the holder 3, ie on the side of the holder 3 which is opposite the container receptacles 32. A T-slot is shown.
  • a dovetail groove or some other retaining groove can also be provided.
  • the groove 33 extends along the longitudinal axis L, at least over the area of the holder 3 which includes the container receptacles 32.
  • the groove 33 is open at the first end 30 of the holder 3, so that the elevations 210, 220 can easily be moved into the groove 33.
  • a handle 34 is arranged with which the holder 3 can be easily gripped by hand.
  • a recess 340 is provided in the handle 34, which enables the reading unit 82 to recognize that the holder 3 has been pushed completely into the swivel mount 2.
  • the Figure 8 shows a sketched perspective representation of a handling unit 9 which can be pushed into the mixing apparatus of the second or third embodiment.
  • the handling unit 9 is designed in such a way that it has a holder 3 according to FIG Figure 4 can accommodate. Accordingly, first and second receptacles 92, 93 are provided, which are designed to be complementary to the first and second ends 30, 31 of the holder 3.
  • the receptacles 92, 93 of the handling unit 9 are connected by a plate 90 which extends along the longitudinal axis L.
  • a groove 91 is provided on the underside of the plate 90, that is to say on the side of the plate which is opposite the receptacles 92, 93.
  • the groove 91 is designed as a T-groove or the like and extends at least over the area of the plate 90 that lies between the two receptacles 92, 93. On the side of the first receptacle 92, the groove 91 is designed to be open to the outside. A handle 94 with a recess 940 is provided on the side of the second receptacle 93. Spacers can be used in the handling unit 9, similar to those in connection with FIG Figure 2 described spacers. Alternatively Handling units 9 with differently designed plates 90 or receptacles 92, 93 can be provided.
  • FIG. 11 shows a perspective view of a mixing plant with a mixing apparatus from FIG Figure 1 , which is pivoted aligned and a non-pivoted mixer. Both apparatuses are arranged with receiving elements 800 on the work surface 80, which are arranged on the machine stand 8.
  • the mixing system further comprises the pipetting unit 81 with the transport unit 810 and the pipette tips 811.
  • the transport unit 810 can transport the pipette tips 811 over the work surface 80 in a first horizontal direction X, in a second horizontal direction Y and in a vertical direction Move direction Z.
  • a reading unit 82 is arranged next to the mixing apparatus on the work surface 80. The reading unit 82 is also aligned and secured with the receiving elements 800 on the work surface 80.
  • handling units 9 can be pushed with the handles 94 over the receiving elements 800 in order to recognize the markings on the container 7 arranged in holders 3.
  • REFERENCE LIST 1 Drive unit 33 Groove 10 drive 34 Handle 11th shaft 340 Recess 2 Swivel mount 4th Retaining element 20th Base plate 5
  • Storage unit 21 first shot 50 Recess 210 Elevation 6th Connecting plate 22nd second shot 60
  • Recess 220 Elevation 7th container 23 first spacers 70 container 24 second spacer 8th Machine stand 25th third shot 80 Work surface 3 holder 800
  • Receiving elements 30th first end 81 Pipetting unit 300 Recess 810 Transport unit 31 second end 811 Pipette tip 310 Recess 82
  • Reading unit 32 Container holder 9 Handling unit 320 slot 90 plate 321 window 91 Groove 322 Clamping lug 92 first shot 323 Tab plate 93 second shot 94 Handle A.
  • Swivel axis 940 Recess L. Longitudinal axi

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Accessories For Mixers (AREA)
EP21191494.0A 2018-07-25 2018-07-25 Appareil de mélange, installation de mélange et procédé de mélange de substances dans des récipients fermés Pending EP3932532A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP21191494.0A EP3932532A1 (fr) 2018-07-25 2018-07-25 Appareil de mélange, installation de mélange et procédé de mélange de substances dans des récipients fermés

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP21191494.0A EP3932532A1 (fr) 2018-07-25 2018-07-25 Appareil de mélange, installation de mélange et procédé de mélange de substances dans des récipients fermés
EP18185420.9A EP3599013A1 (fr) 2018-07-25 2018-07-25 Appareil de mélange

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
EP18185420.9A Division EP3599013A1 (fr) 2018-07-25 2018-07-25 Appareil de mélange

Publications (1)

Publication Number Publication Date
EP3932532A1 true EP3932532A1 (fr) 2022-01-05

Family

ID=63047178

Family Applications (4)

Application Number Title Priority Date Filing Date
EP18185420.9A Withdrawn EP3599013A1 (fr) 2018-07-25 2018-07-25 Appareil de mélange
EP21191494.0A Pending EP3932532A1 (fr) 2018-07-25 2018-07-25 Appareil de mélange, installation de mélange et procédé de mélange de substances dans des récipients fermés
EP19742060.7A Active EP3826757B1 (fr) 2018-07-25 2019-07-24 Appareil de mélange
EP23159223.9A Pending EP4218996A1 (fr) 2018-07-25 2019-07-24 Appareil mélangeur, système mélangeur et procédé pour mélanger des substances dans conteneurs fermés

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP18185420.9A Withdrawn EP3599013A1 (fr) 2018-07-25 2018-07-25 Appareil de mélange

Family Applications After (2)

Application Number Title Priority Date Filing Date
EP19742060.7A Active EP3826757B1 (fr) 2018-07-25 2019-07-24 Appareil de mélange
EP23159223.9A Pending EP4218996A1 (fr) 2018-07-25 2019-07-24 Appareil mélangeur, système mélangeur et procédé pour mélanger des substances dans conteneurs fermés

Country Status (4)

Country Link
US (1) US11969700B2 (fr)
EP (4) EP3599013A1 (fr)
CN (2) CN112469496B (fr)
WO (1) WO2020020923A1 (fr)

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Publication number Priority date Publication date Assignee Title
US10967341B2 (en) * 2018-07-25 2021-04-06 Tecan Trading Ag Mixing device

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CN112469496B (zh) 2023-06-16
EP3826757A1 (fr) 2021-06-02
WO2020020923A1 (fr) 2020-01-30
EP4218996A1 (fr) 2023-08-02
CN116550196A (zh) 2023-08-08
US20210260541A1 (en) 2021-08-26
EP3826757B1 (fr) 2023-04-26
US11969700B2 (en) 2024-04-30
EP3599013A1 (fr) 2020-01-29

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