EP3481288A4 - Hirnnavigationsverfahren und -vorrichtung - Google Patents

Hirnnavigationsverfahren und -vorrichtung Download PDF

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Publication number
EP3481288A4
EP3481288A4 EP17823773.1A EP17823773A EP3481288A4 EP 3481288 A4 EP3481288 A4 EP 3481288A4 EP 17823773 A EP17823773 A EP 17823773A EP 3481288 A4 EP3481288 A4 EP 3481288A4
Authority
EP
European Patent Office
Prior art keywords
navigation methods
brain navigation
brain
methods
navigation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP17823773.1A
Other languages
English (en)
French (fr)
Other versions
EP3481288A2 (de
Inventor
Hagai Bergman
Omer Naor
Jubran ELFAR
Imad Younis
Adi Balan
Zvi Israel
Dan VALSKY
Odeya MARMOR
Renana EITAN
John Rizik
Majd SLEEM
Paul MCSHERRY
Steven Scott
Benjamin MATTER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alpha Omega Engineering Ltd
Original Assignee
Alpha Omega Neuro Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/IL2017/050328 external-priority patent/WO2017158604A1/en
Application filed by Alpha Omega Neuro Technologies Ltd filed Critical Alpha Omega Neuro Technologies Ltd
Publication of EP3481288A2 publication Critical patent/EP3481288A2/de
Publication of EP3481288A4 publication Critical patent/EP3481288A4/de
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7207Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts
    • A61B5/7214Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts using signal cancellation, e.g. based on input of two identical physiological sensors spaced apart, or based on two signals derived from the same sensor, for different optical wavelengths
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10Computer-aided planning, simulation or modelling of surgical operations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053Measuring electrical impedance or conductance of a portion of the body
    • A61B5/0538Measuring electrical impedance or conductance of a portion of the body invasively, e.g. using a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25Bioelectric electrodes therefor
    • A61B5/279Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/291Bioelectric electrodes therefor specially adapted for particular uses for electroencephalography [EEG]
    • A61B5/293Invasive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • A61B5/372Analysis of electroencephalograms
    • A61B5/374Detecting the frequency distribution of signals, e.g. detecting delta, theta, alpha, beta or gamma waves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • A61B5/375Electroencephalography [EEG] using biofeedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • A61B5/377Electroencephalography [EEG] using evoked responses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • A61B5/377Electroencephalography [EEG] using evoked responses
    • A61B5/383Somatosensory stimuli, e.g. electric stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6867Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
    • A61B5/6868Brain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271Specific aspects of physiological measurement analysis
    • A61B5/7278Artificial waveform generation or derivation, e.g. synthesising signals from measured signals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526Head electrodes
    • A61N1/0529Electrodes for brain stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551Spinal or peripheral nerve electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36062Spinal stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36125Details of circuitry or electric components
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N20/00Machine learning
    • G06N20/10Machine learning using kernel methods, e.g. support vector machines [SVM]
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N7/00Computing arrangements based on specific mathematical models
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10Computer-aided planning, simulation or modelling of surgical operations
    • A61B2034/107Visualisation of planned trajectories or target regions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • A61B2034/2046Tracking techniques
    • A61B2034/2048Tracking techniques using an accelerometer or inertia sensor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/04Arrangements of multiple sensors of the same type
    • A61B2562/043Arrangements of multiple sensors of the same type in a linear array
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526Head electrodes
    • A61N1/0529Electrodes for brain stimulation
    • A61N1/0534Electrodes for deep brain stimulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Neurosurgery (AREA)
  • Artificial Intelligence (AREA)
  • Theoretical Computer Science (AREA)
  • Software Systems (AREA)
  • Signal Processing (AREA)
  • Cardiology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Physics & Mathematics (AREA)
  • Data Mining & Analysis (AREA)
  • Evolutionary Computation (AREA)
  • Computing Systems (AREA)
  • General Engineering & Computer Science (AREA)
  • Mathematical Physics (AREA)
  • Robotics (AREA)
  • Physiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Computational Mathematics (AREA)
  • Pure & Applied Mathematics (AREA)
  • Algebra (AREA)
  • Mathematical Analysis (AREA)
EP17823773.1A 2016-07-07 2017-07-07 Hirnnavigationsverfahren und -vorrichtung Pending EP3481288A4 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662359615P 2016-07-07 2016-07-07
US201662370806P 2016-08-04 2016-08-04
US201762459415P 2017-02-15 2017-02-15
US201762459422P 2017-02-15 2017-02-15
PCT/IL2017/050328 WO2017158604A1 (en) 2016-03-14 2017-03-14 Brain navigation lead
PCT/IL2017/050763 WO2018008034A2 (en) 2016-07-07 2017-07-07 Brain navigation methods and device

Publications (2)

Publication Number Publication Date
EP3481288A2 EP3481288A2 (de) 2019-05-15
EP3481288A4 true EP3481288A4 (de) 2020-04-08

Family

ID=60912449

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17823773.1A Pending EP3481288A4 (de) 2016-07-07 2017-07-07 Hirnnavigationsverfahren und -vorrichtung

Country Status (3)

Country Link
EP (1) EP3481288A4 (de)
CN (2) CN109788903B (de)
WO (1) WO2018008034A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
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US11051889B2 (en) 2015-05-10 2021-07-06 Alpha Omega Engineering Ltd. Brain navigation methods and device
US11234632B2 (en) 2015-05-10 2022-02-01 Alpha Omega Engineering Ltd. Brain navigation lead
EP3787495A4 (de) * 2018-05-03 2022-02-16 Deep Brain Stimulation Technologies Pty. Ltd. Systeme und verfahren zur überwachung der nervenaktivität
WO2020049514A1 (en) * 2018-09-06 2020-03-12 Alpha Omega Neuro Technologies Ltd. Therapeutic space assessment
FR3088535A1 (fr) * 2018-11-16 2020-05-22 Universite de Bordeaux Methode de determination d'une cible cerebrale stereotaxique
EP3990103A4 (de) 2019-06-26 2023-07-19 Alpha Omega Engineering Ltd. Hirnnavigationsleitungspositionierung und verfahren dafür
US20210038190A1 (en) * 2019-08-08 2021-02-11 Endra Life Sciences Inc. Method and system for identifying a material of interest
CN111436923B (zh) * 2020-03-27 2022-05-20 武汉联影智融医疗科技有限公司 穿刺路径确定装置、手术导航系统、设备及存储介质
EP4175549A1 (de) * 2020-08-10 2023-05-10 Boston Scientific Neuromodulation Corporation Elektrische stimulationssysteme auf basis von stimulationsermöglichten reaktionen
CN112751345B (zh) * 2020-12-30 2022-10-25 电子科技大学 基于lstm与相轨迹的电力系统低频振荡模态辨识方法
WO2022198172A1 (en) 2021-03-18 2022-09-22 Boston Scientific Neuromodulation Corporation Systems for lead movement detection and response in dbs therapy
CN113520437A (zh) * 2021-07-07 2021-10-22 上海中医药大学 一种基于颈部ct扫描影像的环咽肌经皮定位方法
US20230099390A1 (en) * 2021-09-24 2023-03-30 Boston Scientific Neuromodulation Corporation Using Evoked Potentials for Brain Stimulation Therapies
US20240138915A1 (en) * 2022-10-27 2024-05-02 Medtronic Navigation, Inc. Method And Apparatus For Planning Placement Of An Implant

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US20120053659A1 (en) * 2010-09-01 2012-03-01 Medtronic, Inc. Symmetrical physiological signal sensing with a medical device

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US20120053659A1 (en) * 2010-09-01 2012-03-01 Medtronic, Inc. Symmetrical physiological signal sensing with a medical device

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Title
See also references of WO2018008034A2 *

Also Published As

Publication number Publication date
WO2018008034A3 (en) 2018-02-08
WO2018008034A2 (en) 2018-01-11
EP3481288A2 (de) 2019-05-15
CN115517764A (zh) 2022-12-27
CN109788903B (zh) 2022-11-08
CN109788903A (zh) 2019-05-21

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