EP3322484A4 - Compositions et méthodes pour le traitement du cancer - Google Patents
Compositions et méthodes pour le traitement du cancer Download PDFInfo
- Publication number
- EP3322484A4 EP3322484A4 EP16825114.8A EP16825114A EP3322484A4 EP 3322484 A4 EP3322484 A4 EP 3322484A4 EP 16825114 A EP16825114 A EP 16825114A EP 3322484 A4 EP3322484 A4 EP 3322484A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compositions
- methods
- treating cancer
- cancer
- treating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57496—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/715—Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons
- G01N2333/7158—Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562192204P | 2015-07-14 | 2015-07-14 | |
PCT/US2016/042100 WO2017011559A1 (fr) | 2015-07-14 | 2016-07-13 | Compositions et méthodes pour le traitement du cancer |
Publications (3)
Publication Number | Publication Date |
---|---|
EP3322484A1 EP3322484A1 (fr) | 2018-05-23 |
EP3322484A4 true EP3322484A4 (fr) | 2019-03-06 |
EP3322484B1 EP3322484B1 (fr) | 2021-03-24 |
Family
ID=57757548
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP16825114.8A Active EP3322484B1 (fr) | 2015-07-14 | 2016-07-13 | Méthode de détection de cellules souches cancéreuses |
Country Status (13)
Country | Link |
---|---|
US (3) | US20180237515A1 (fr) |
EP (1) | EP3322484B1 (fr) |
JP (1) | JP6895946B2 (fr) |
KR (1) | KR20180027568A (fr) |
CN (1) | CN107847764B (fr) |
AU (2) | AU2016291803A1 (fr) |
CA (1) | CA2992091A1 (fr) |
ES (1) | ES2871252T3 (fr) |
HK (1) | HK1250958A1 (fr) |
IL (1) | IL256763A (fr) |
RU (1) | RU2729396C2 (fr) |
SG (1) | SG10201912086QA (fr) |
WO (1) | WO2017011559A1 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP4278016A1 (fr) | 2021-01-15 | 2023-11-22 | Universite De Fribourg | Biomarqueurs pour la détection du cancer du sein |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009156994A1 (fr) * | 2008-06-24 | 2009-12-30 | Hadasit Medical Research Services And Development Ltd. | Anticorps spécifiques de ccl20 pour la thérapie du cancer |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20050011741A (ko) | 2002-04-11 | 2005-01-29 | 메드이뮨 백신즈 인코포레이티드 | 분무 건조에 의한 생물학적 활성 물질의 보존 |
WO2003086443A1 (fr) | 2002-04-11 | 2003-10-23 | Medimmune Vaccines, Inc. | Lyophilisation par pulverisation de compositions pour administration intranasale |
CA2849556A1 (fr) | 2002-04-11 | 2003-10-23 | Vu Truong-Le | Conservation de matieres bio-actives au moyen de mousse lyophilisee |
AU2003234090A1 (en) | 2002-04-11 | 2003-10-27 | Medimmune Vaccines, Inc. | Spray freeze dry of compositions for pulmonary administration |
EP1581639A4 (fr) | 2002-12-17 | 2006-03-08 | Medimmune Vaccines Inc | Pulv risation haute pression de mat riaux bioactifs |
US20070099209A1 (en) * | 2005-06-13 | 2007-05-03 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
EP2069401A4 (fr) | 2007-07-31 | 2011-02-23 | Medimmune Llc | Protéines de liaison à épitope multispécifiques et leurs utilisations |
EP2166021A1 (fr) * | 2008-09-16 | 2010-03-24 | Ganymed Pharmaceuticals AG | Anticorps monoclonaux pour le traitement du cancer |
KR100950195B1 (ko) * | 2009-03-20 | 2010-03-29 | 서울대학교산학협력단 | Znf281을 발현하는 제대혈 유래 만능 줄기세포의 분리방법 |
JP5864564B2 (ja) * | 2010-06-28 | 2016-02-17 | ユニベルシテーツクリニクム フライブルグ | 線維性疾患および癌における治療選択肢としてのccr6を介するccl18シグナル伝達の遮断 |
EP2640744A4 (fr) * | 2010-11-19 | 2014-05-28 | Eisai R&D Man Co Ltd | Neutralisation d'anticorps anti-ccl20 |
WO2012122015A2 (fr) * | 2011-03-04 | 2012-09-13 | Immune Disease Institute, Inc. | Inhibiteurs sélectifs de cellules initiatrices de tumeur |
EP2729488A4 (fr) | 2011-07-06 | 2015-01-14 | Medimmune Llc | Procédé de préparation de polypeptides multimères |
US9057055B2 (en) * | 2012-12-05 | 2015-06-16 | The Royal Institution For The Advancement Of Learning/Mcgill University | Method of obtaining circulating cancer cell populations |
-
2016
- 2016-07-13 SG SG10201912086QA patent/SG10201912086QA/en unknown
- 2016-07-13 WO PCT/US2016/042100 patent/WO2017011559A1/fr active Application Filing
- 2016-07-13 KR KR1020187003742A patent/KR20180027568A/ko unknown
- 2016-07-13 US US15/743,384 patent/US20180237515A1/en not_active Abandoned
- 2016-07-13 CN CN201680041275.7A patent/CN107847764B/zh active Active
- 2016-07-13 CA CA2992091A patent/CA2992091A1/fr not_active Abandoned
- 2016-07-13 ES ES16825114T patent/ES2871252T3/es active Active
- 2016-07-13 RU RU2018105217A patent/RU2729396C2/ru active
- 2016-07-13 JP JP2018501231A patent/JP6895946B2/ja active Active
- 2016-07-13 EP EP16825114.8A patent/EP3322484B1/fr active Active
- 2016-07-13 AU AU2016291803A patent/AU2016291803A1/en not_active Abandoned
-
2018
- 2018-01-07 IL IL256763A patent/IL256763A/en unknown
- 2018-08-13 HK HK18110314.8A patent/HK1250958A1/zh unknown
-
2019
- 2019-09-12 AU AU2019229394A patent/AU2019229394A1/en not_active Abandoned
- 2019-10-14 US US16/601,140 patent/US20200102382A1/en not_active Abandoned
-
2021
- 2021-06-14 US US17/346,876 patent/US20210380673A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009156994A1 (fr) * | 2008-06-24 | 2009-12-30 | Hadasit Medical Research Services And Development Ltd. | Anticorps spécifiques de ccl20 pour la thérapie du cancer |
Non-Patent Citations (5)
Title |
---|
DARASH-YAHANA MERAV ET AL: "Pro-tumorigenic roles for CCL20, CCR6, IL-23 and Th17 cells in human prostate cancer", AMERICAN ASSOCIATION FOR CANCER RESEARCH. PROCEEDINGS OF THE ANNUAL MEETING, AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, vol. 49, 1 April 2008 (2008-04-01), pages 1281, XP009123895, ISSN: 0197-016X * |
KANG-JIE CHEN ET AL: "Selective Recruitment of Regulatory T Cell through CCR6-CCL20 in Hepatocellular Carcinoma Fosters Tumor Progression and Predicts Poor Prognosis", PLOS ONE, vol. 6, no. 9, 14 September 2011 (2011-09-14), pages e24671, XP055320611, DOI: 10.1371/journal.pone.0024671 * |
KLEEFF J ET AL: "DETECTION AND LOCALIZATION OF MIP-3ALPHA/LARC/EXODUS, A MACROPHAGE PROINFLAMMATORY CHEMOKINE, AND ITS CCR6 RECEPTOR IN HUMAN PANCREATIC CANCER", INTERNATIONAL JOURNAL OF CA, JOHN WILEY & SONS, INC, US, vol. 81, no. 4, 17 May 1999 (1999-05-17), pages 650 - 657, XP008054224, ISSN: 0020-7136, DOI: 10.1002/(SICI)1097-0215(19990517)81:4<650::AID-IJC23>3.0.CO;2-# * |
RUBIE CLAUDIA ET AL: "CCL20/CCR6 expression profile in pancreatic cancer", JOURNAL OF TRANSLATIONAL MEDICINE, BIOMED CENTRAL, vol. 8, no. 1, 10 May 2010 (2010-05-10), pages 45, XP021078872, ISSN: 1479-5876, DOI: 10.1186/1479-5876-8-45 * |
See also references of WO2017011559A1 * |
Also Published As
Publication number | Publication date |
---|---|
KR20180027568A (ko) | 2018-03-14 |
AU2016291803A1 (en) | 2018-02-22 |
CA2992091A1 (fr) | 2017-01-19 |
RU2729396C2 (ru) | 2020-08-06 |
HK1250958A1 (zh) | 2019-01-18 |
WO2017011559A8 (fr) | 2018-02-01 |
ES2871252T3 (es) | 2021-10-28 |
RU2018105217A (ru) | 2019-08-14 |
EP3322484B1 (fr) | 2021-03-24 |
US20200102382A1 (en) | 2020-04-02 |
JP2018520177A (ja) | 2018-07-26 |
RU2018105217A3 (fr) | 2020-01-27 |
US20210380673A1 (en) | 2021-12-09 |
CN107847764B (zh) | 2022-07-05 |
IL256763A (en) | 2018-03-29 |
US20180237515A1 (en) | 2018-08-23 |
AU2019229394A1 (en) | 2019-10-03 |
JP6895946B2 (ja) | 2021-06-30 |
WO2017011559A1 (fr) | 2017-01-19 |
EP3322484A1 (fr) | 2018-05-23 |
SG10201912086QA (en) | 2020-02-27 |
CN107847764A (zh) | 2018-03-27 |
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