EP3294403B1 - Chest drainage system - Google Patents

Chest drainage system Download PDF

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Publication number
EP3294403B1
EP3294403B1 EP16793364.7A EP16793364A EP3294403B1 EP 3294403 B1 EP3294403 B1 EP 3294403B1 EP 16793364 A EP16793364 A EP 16793364A EP 3294403 B1 EP3294403 B1 EP 3294403B1
Authority
EP
European Patent Office
Prior art keywords
fluid
circulation assembly
concentration
sensor
control unit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP16793364.7A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP3294403A4 (en
EP3294403A1 (en
Inventor
Wolfram Grziwa
Greg Peatfield
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Atrium Medical Corp
Original Assignee
Atrium Medical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Atrium Medical Corp filed Critical Atrium Medical Corp
Publication of EP3294403A1 publication Critical patent/EP3294403A1/en
Publication of EP3294403A4 publication Critical patent/EP3294403A4/en
Application granted granted Critical
Publication of EP3294403B1 publication Critical patent/EP3294403B1/en
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Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/71Suction drainage systems
    • A61M1/73Suction drainage systems comprising sensors or indicators for physical values
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/02Gases
    • A61M2202/0225Carbon oxides, e.g. Carbon dioxide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • A61M2205/3334Measuring or controlling the flow rate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/10Trunk
    • A61M2210/101Pleural cavity

Definitions

  • the inhaled air will only slowly leak from the lungs, thus providing oxygen in the inhaled air to have more time to undergo at least some degree of oxygen-carbon dioxide exchange within the lung, resulting in a relatively higher concentration of carbon dioxide leaking into the pleural space (e.g., between 4-6%, or otherwise approaching or approximating end tidal CO 2 , which may be higher or lower than 4-6% depending upon the particular patient and/or the patient's use of a ventilator).
  • a determination of whether or not a leak is present may be assisted by monitoring the concentration of the CO 2 in the pleural space.
  • the display unit 36 may be programmed with the CPU 34 to representatively display different colors, icons, symbols, characters, text, images, etc., that represent the concentration of the reference gas detected by the sensor 30.
  • the CPU may alternatively and/or additionally be used to trigger an audible cue, sound, recorded message, etc., from one or more speakers coupled thereto.
  • Trend lines as discussed above may additionally be helpful in determining the rate of healing of a leak and/or the estimate or forecast as to when a leak is likely to be healed. For example, if the slope of a trend line is negative, thereby indicating healing, it may be extrapolated or estimated according to any known or developed extrapolation or estimation methods to determine when the reference gas concentration is likely to fall below a threshold value.
  • a system 90 is illustrated in Figure 8 in order to show an example in which the circulation assembly 20 is combined in a single intake/exhaust device 92. That is, the device 92 combines the functions of both the devices 22 and 24 described above.
  • the device 92 may be arranged as a three way valve that selectively connects the tubing circuit 14 to either the intake 26 or the exhaust 28.
  • the device 92 may be arranged as a reversible pump, such that the intake 26 and the exhaust 28 are formed by the same port, opening, or aperture and the pump operates in opposite directions to either push fluid into the system 90 or to exhaust fluid out of the system 90.
  • the circulation assembly 20 may be at least partially controlled by sensing one or more parameters other than reference gas concentration.
  • the system 90 illustrates a pressure sensor 94 that can be used for this purpose, namely, to conduct a signal upon the sensor 94 measuring a corresponding pressure to control operation of the circulation assembly 20, namely, the device 92.
  • the device 92 could be arranged to fluidically connect the tubing circuit 14 to the intake 26 (or if the device 92 is arranged as a pump, operate the pump in a first direction) when or until a first pressure is achieved, and to fluidically connect the tubing circuit 14 to the exhaust (or if the device 92 is arranged as a pump, operate the pump in a second direction) when or until a second pressure is achieved

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Vascular Medicine (AREA)
  • External Artificial Organs (AREA)
EP16793364.7A 2015-05-13 2016-05-10 Chest drainage system Active EP3294403B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562160833P 2015-05-13 2015-05-13
PCT/US2016/031623 WO2016183070A1 (en) 2015-05-13 2016-05-10 Chest drainage system

Publications (3)

Publication Number Publication Date
EP3294403A1 EP3294403A1 (en) 2018-03-21
EP3294403A4 EP3294403A4 (en) 2019-03-20
EP3294403B1 true EP3294403B1 (en) 2022-02-23

Family

ID=57249470

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16793364.7A Active EP3294403B1 (en) 2015-05-13 2016-05-10 Chest drainage system

Country Status (6)

Country Link
US (2) US10195404B2 (enrdf_load_stackoverflow)
EP (1) EP3294403B1 (enrdf_load_stackoverflow)
JP (1) JP6791559B2 (enrdf_load_stackoverflow)
CN (1) CN108136162B (enrdf_load_stackoverflow)
AU (2) AU2016261628B2 (enrdf_load_stackoverflow)
WO (1) WO2016183070A1 (enrdf_load_stackoverflow)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160235623A1 (en) * 2015-02-16 2016-08-18 Michael Mirzoyan Invasive Intermittent Negative Pressure Ventilation
WO2018136232A1 (en) * 2017-01-23 2018-07-26 Kci Licensing, Inc. Negative-pressure systems for the management of pleural effusion
CN108066832B (zh) * 2017-12-11 2020-09-01 王大娟 一种用于胸腔积液与排气的引流装置
WO2020021520A1 (en) * 2018-07-25 2020-01-30 Palliare Limited Leak detecting apparatus, and a method for detecting a leak in a hollow organ or lumen in a human or animal body
CN109394201A (zh) * 2018-12-07 2019-03-01 刘铁楠 一种气胸治疗监测装置
GB2590644B (en) * 2019-12-20 2023-06-14 Gamida Tech Preparation and delivery of fluids for surgery
WO2021150999A1 (en) * 2020-01-25 2021-07-29 Centese, Inc. Devices and methods for managing chest or wound drainage
US11484634B2 (en) * 2020-05-28 2022-11-01 C. Thomas Black Chest tube air leak detection system
SE546314C2 (en) * 2020-10-19 2024-10-01 Thoragen Ab Improved body drainage apparatus
WO2024142145A1 (ja) * 2022-12-26 2024-07-04 国立大学法人東北大学 空気漏れ測定システム、空気漏れ測定用装置および空気漏れ測定方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4654029A (en) 1982-12-13 1987-03-31 Howmedica, Inc. Electronic drainage system
CN86201261U (zh) * 1986-03-07 1987-01-28 段禄轲 医用镇痛自控电动吸引器
DE4306478A1 (de) * 1993-03-02 1994-09-08 Wolfgang Dr Wagner Drainagevorrichtung, insbesondere Pleuradrainagevorrichtung, und Drainageverfahren
US7122018B2 (en) * 2000-12-26 2006-10-17 Sensormedics Corporation Device and method for treatment of wounds with nitric oxide
JP4301945B2 (ja) 2001-09-10 2009-07-22 パルモンクス 気管支内診断のための方法および装置
US7207946B2 (en) * 2002-05-09 2007-04-24 Spiration, Inc. Automated provision of information related to air evacuation from a chest cavity
EP1782727A3 (en) 2002-10-03 2007-07-25 Etview Ltd. Tube for inspecting internal organs of a body
ES2328908T3 (es) * 2002-11-07 2009-11-19 Rolf Weidenhagen Sistema endoscopico para el tratamiento de heridas.
CA2515439A1 (en) 2003-02-07 2004-08-26 Ramez Emile Necola Shehada Surgical drain with sensors for monitoring internal tissue condition and for monitoring fluid in lumen
SE528370C2 (sv) 2003-06-19 2006-10-31 Millicore Ab Dräneringsanordning
KR20070033024A (ko) 2004-07-16 2007-03-23 슈이치 도쿠나가 기관 내 담의 흡인장치
WO2007024230A1 (en) * 2005-08-26 2007-03-01 Spheric Products, Ltd. Chest tube drainage system
CA2994429C (en) 2008-01-25 2019-12-03 The Cleveland Clinic Foundation Methods and devices to clear obstructions from medical tubes
US8246752B2 (en) * 2008-01-25 2012-08-21 Clear Catheter Systems, Inc. Methods and devices to clear obstructions from medical tubes
US20110180064A1 (en) * 2008-02-19 2011-07-28 Portaero, Inc. Methods and devices for follow-up care and treatment of a pneumstoma
AU2009242611A1 (en) 2008-05-01 2009-11-05 Spiration, Inc. Direct lung sensor systems, methods, and apparatuses
CN201253371Y (zh) * 2008-07-22 2009-06-10 吴声堂 单向阀气胸排气管
EP2189171A1 (en) 2008-11-25 2010-05-26 Covidien AG Mobile chest drainage unit, thoracic catheter, system comprising a mobile chest drainage unit and a thoracic catheter, and manufacturing method thereof
US8882678B2 (en) 2009-03-13 2014-11-11 Atrium Medical Corporation Pleural drainage system and method of use
TR200903881A2 (tr) * 2009-05-20 2009-12-21 Bayraktar Volkan Portatif pnömotoraks cihazı.
JP6325440B2 (ja) * 2011-06-23 2018-05-16 メデラ ホールディング アーゲー 陰圧の手段によって身体から流動体を吸引するためのシステム
US20130165877A1 (en) * 2011-12-21 2013-06-27 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Augmented chest tube drainage system and method with volume sensing, automated alerts and messaging capability
EP2814390B1 (en) * 2012-02-16 2020-07-15 Board of Regents of the University of Nebraska System for monitoring pleural fluid
WO2015095787A1 (en) * 2013-12-20 2015-06-25 Northwestern University Chest tube drainage system with analyzer
EP4000678B1 (en) 2016-03-03 2025-02-12 Esculon, LLC Devices and methods for managing chest drainage
JP2019507666A (ja) 2016-03-07 2019-03-22 アントニチェッリ、アルベルト 胸腔ドレナージ治療をカスタマイズするためのデバイス、システムおよび方法

Also Published As

Publication number Publication date
US20190134363A1 (en) 2019-05-09
US20160331946A1 (en) 2016-11-17
EP3294403A4 (en) 2019-03-20
CN108136162B (zh) 2022-03-01
JP6791559B2 (ja) 2020-11-25
US11129971B2 (en) 2021-09-28
AU2021200642A1 (en) 2021-03-04
AU2016261628B2 (en) 2020-11-05
EP3294403A1 (en) 2018-03-21
JP2018519012A (ja) 2018-07-19
AU2021200642B2 (en) 2022-12-15
US10195404B2 (en) 2019-02-05
AU2016261628A1 (en) 2017-11-23
CN108136162A (zh) 2018-06-08
WO2016183070A1 (en) 2016-11-17

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