EP3276341A4 - Phase stationnaire pour chromatographie à fluide supercritique - Google Patents

Phase stationnaire pour chromatographie à fluide supercritique Download PDF

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Publication number
EP3276341A4
EP3276341A4 EP16768899.3A EP16768899A EP3276341A4 EP 3276341 A4 EP3276341 A4 EP 3276341A4 EP 16768899 A EP16768899 A EP 16768899A EP 3276341 A4 EP3276341 A4 EP 3276341A4
Authority
EP
European Patent Office
Prior art keywords
supercritical fluid
stationary phase
fluid chromatography
chromatography
supercritical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP16768899.3A
Other languages
German (de)
English (en)
Other versions
EP3276341A1 (fr
EP3276341B1 (fr
Inventor
Kanji NAGAI
Satoshi Shinkura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daicel Corp
Original Assignee
Daicel Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daicel Corp filed Critical Daicel Corp
Priority to EP22173260.5A priority Critical patent/EP4063849B1/fr
Publication of EP3276341A1 publication Critical patent/EP3276341A1/fr
Publication of EP3276341A4 publication Critical patent/EP3276341A4/fr
Application granted granted Critical
Publication of EP3276341B1 publication Critical patent/EP3276341B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/40—Selective adsorption, e.g. chromatography characterised by the separation mechanism using supercritical fluid as mobile phase or eluent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28016—Particle form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28042—Shaped bodies; Monolithic structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/288—Polar phases
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204—Inorganic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3278—Polymers being grafted on the carrier
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3291—Characterised by the shape of the carrier, the coating or the obtained coated product
    • B01J20/3293—Coatings on a core, the core being particle or fiber shaped, e.g. encapsulated particles, coated fibers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/44—Polymerisation in the presence of compounding ingredients, e.g. plasticisers, dyestuffs, fillers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L39/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions of derivatives of such polymers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
EP16768899.3A 2015-03-24 2016-03-24 Phase stationnaire pour chromatographie à fluide supercritique Active EP3276341B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP22173260.5A EP4063849B1 (fr) 2015-03-24 2016-03-24 Phase stationnaire pour chromatographie liquide supercritique

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015061483 2015-03-24
PCT/JP2016/059456 WO2016152996A1 (fr) 2015-03-24 2016-03-24 Phase stationnaire pour chromatographie à fluide supercritique

Related Child Applications (2)

Application Number Title Priority Date Filing Date
EP22173260.5A Division EP4063849B1 (fr) 2015-03-24 2016-03-24 Phase stationnaire pour chromatographie liquide supercritique
EP22173260.5A Division-Into EP4063849B1 (fr) 2015-03-24 2016-03-24 Phase stationnaire pour chromatographie liquide supercritique

Publications (3)

Publication Number Publication Date
EP3276341A1 EP3276341A1 (fr) 2018-01-31
EP3276341A4 true EP3276341A4 (fr) 2018-11-14
EP3276341B1 EP3276341B1 (fr) 2022-07-27

Family

ID=56977460

Family Applications (2)

Application Number Title Priority Date Filing Date
EP16768899.3A Active EP3276341B1 (fr) 2015-03-24 2016-03-24 Phase stationnaire pour chromatographie à fluide supercritique
EP22173260.5A Active EP4063849B1 (fr) 2015-03-24 2016-03-24 Phase stationnaire pour chromatographie liquide supercritique

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP22173260.5A Active EP4063849B1 (fr) 2015-03-24 2016-03-24 Phase stationnaire pour chromatographie liquide supercritique

Country Status (5)

Country Link
US (1) US11065558B2 (fr)
EP (2) EP3276341B1 (fr)
JP (2) JP6791844B2 (fr)
CN (1) CN107430100B (fr)
WO (1) WO2016152996A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6791844B2 (ja) * 2015-03-24 2020-11-25 株式会社ダイセル 超臨界流体クロマトグラフィー用の固定相
US10451602B2 (en) * 2016-03-31 2019-10-22 Exxonmobil Research And Engineering Company Composition and method of screening hydrocarbons to limit potential toxicological hazards
JP7067545B2 (ja) * 2017-03-23 2022-05-16 コニカミノルタ株式会社 有機エレクトロルミネッセンス素子用材料の回収方法及び有機エレクトロルミネッセンス素子用材料の製造方法
JP2021508344A (ja) * 2017-10-02 2021-03-04 ユニベルシテ パリ−サクレーＵｎｉｖｅｒｓｉｔｅ Ｐａｒｉｓ−Ｓａｃｌａｙ 新規グラフトポリマー、その製造方法及び使用、特に金属捕捉のための使用
JPWO2019116974A1 (ja) * 2017-12-15 2021-01-21 コニカミノルタ株式会社 多孔性微粒子、クロマトグラフィー用充填剤及びクロマトグラフィー用カラム
WO2019117063A1 (fr) * 2017-12-15 2019-06-20 コニカミノルタ株式会社 Microparticules poreuses, leur procédé de production, remplissage chromatographique et colonne chromatographique
JP7144176B2 (ja) * 2018-04-13 2022-09-29 株式会社島津製作所 抽出物の回収方法および分析方法
CN108760953B (zh) * 2018-06-11 2021-02-19 梧州市食品药品检验所 同时检测复方感冒灵片中对乙酰氨基酚、氯苯那敏、咖啡因和绿原酸含量的快速检测方法
US20210252479A1 (en) 2018-08-30 2021-08-19 Daicel Corporation Stationary phase for chromatography
WO2021078760A1 (fr) * 2019-10-24 2021-04-29 Merck Patent Gmbh Matériau et procédé pour réaliser une séparation sur la base d'une liaison halogène
CN117980066A (zh) 2021-09-29 2024-05-03 株式会社大赛璐 柱色谱用固定相的制造方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060247362A1 (en) * 2005-05-02 2006-11-02 Varian, Inc. Polymer modified porous substrate for solid phase extraction
EP2848932A1 (fr) * 2012-05-10 2015-03-18 National University Corporation Nagoya University Agent de séparation pour isomère optique

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003337125A (ja) * 2002-05-17 2003-11-28 Kumamoto Technology & Industry Foundation 吸着分離剤、クロマトグラフ用充填剤、クロマトグラフ用カラムおよび液体クロマトグラフ
JP4431009B2 (ja) 2004-08-20 2010-03-10 ダイセル化学工業株式会社 超臨界流体クロマトグラフィー用カラム
JP5224264B2 (ja) * 2006-05-09 2013-07-03 株式会社ダイセル キトサン誘導体の製造方法
GB0810902D0 (en) * 2008-06-13 2008-07-23 Astex Therapeutics Ltd New compounds
CN101837284B (zh) * 2010-05-28 2012-11-07 西北大学 一种聚乙烯基四唑分离介质及其制备方法和应用
JPWO2012023615A1 (ja) 2010-08-20 2013-10-28 株式会社ダイセル クロマト用微粒子及びそれを用いるクロマトグラフィー
WO2014017280A1 (fr) * 2012-07-23 2014-01-30 株式会社ダイセル Phase stationnaire
CN108176078A (zh) * 2013-06-11 2018-06-19 沃特世科技公司 色谱柱和分离装置及其用途
EP3021114B1 (fr) * 2013-07-08 2021-03-03 National University Corporation Kyoto Institute of Technology Agent de séparation
JP6791844B2 (ja) * 2015-03-24 2020-11-25 株式会社ダイセル 超臨界流体クロマトグラフィー用の固定相

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060247362A1 (en) * 2005-05-02 2006-11-02 Varian, Inc. Polymer modified porous substrate for solid phase extraction
EP2848932A1 (fr) * 2012-05-10 2015-03-18 National University Corporation Nagoya University Agent de séparation pour isomère optique

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2016152996A1 *

Also Published As

Publication number Publication date
JPWO2016152996A1 (ja) 2018-01-18
JP7061172B2 (ja) 2022-04-27
US20180050282A1 (en) 2018-02-22
EP3276341A1 (fr) 2018-01-31
EP4063849B1 (fr) 2024-01-31
US11065558B2 (en) 2021-07-20
CN107430100A (zh) 2017-12-01
CN107430100B (zh) 2021-03-19
EP3276341B1 (fr) 2022-07-27
JP6791844B2 (ja) 2020-11-25
EP4063849A1 (fr) 2022-09-28
WO2016152996A1 (fr) 2016-09-29
JP2021015129A (ja) 2021-02-12

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