EP3169300B1 - Sac de perfusion multi-mélange - Google Patents
Sac de perfusion multi-mélange Download PDFInfo
- Publication number
- EP3169300B1 EP3169300B1 EP15821255.5A EP15821255A EP3169300B1 EP 3169300 B1 EP3169300 B1 EP 3169300B1 EP 15821255 A EP15821255 A EP 15821255A EP 3169300 B1 EP3169300 B1 EP 3169300B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- chamber
- dispensing
- bag
- fluid
- infusion bag
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000001802 infusion Methods 0.000 title claims description 61
- 239000012530 fluid Substances 0.000 claims description 72
- 230000000994 depressogenic effect Effects 0.000 claims description 8
- 238000012546 transfer Methods 0.000 claims description 2
- 230000004913 activation Effects 0.000 claims 2
- 230000000881 depressing effect Effects 0.000 claims 2
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 description 50
- 239000003795 chemical substances by application Substances 0.000 description 48
- 238000000034 method Methods 0.000 description 10
- 230000003213 activating effect Effects 0.000 description 7
- 239000000654 additive Substances 0.000 description 7
- 238000000926 separation method Methods 0.000 description 4
- 230000003647 oxidation Effects 0.000 description 3
- 238000007254 oxidation reaction Methods 0.000 description 3
- 238000011109 contamination Methods 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- GDOPTJXRTPNYNR-UHFFFAOYSA-N CC1CCCC1 Chemical compound CC1CCCC1 GDOPTJXRTPNYNR-UHFFFAOYSA-N 0.000 description 1
- 239000004803 Di-2ethylhexylphthalate Substances 0.000 description 1
- 206010014418 Electrolyte imbalance Diseases 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- BJQHLKABXJIVAM-UHFFFAOYSA-N bis(2-ethylhexyl) phthalate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1C(=O)OCC(CC)CCCC BJQHLKABXJIVAM-UHFFFAOYSA-N 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000002642 intravenous therapy Methods 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
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- 238000003825 pressing Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/10—Bag-type containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1406—Septums, pierceable membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1462—Containers with provisions for hanging, e.g. integral adaptations of the container
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1475—Inlet or outlet ports
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2093—Containers having several compartments for products to be mixed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/1407—Infusion of two or more substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/1407—Infusion of two or more substances
- A61M5/1408—Infusion of two or more substances in parallel, e.g. manifolds, sequencing valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/0007—Special media to be introduced, removed or treated introduced into the body
Definitions
- This invention relates generally to an infusion bag and more particularly to a multi-mix infusion bag.
- infusion bags have been critical in the medical industry. These bags have been the means of delivering many types of fluids to patients, for example for various types of intravenous therapies, such as, but not limited to, correcting electrolyte imbalances, delivering medications, transfusing blood, or replacing fluid to correct conditions such as dehydration.
- intravenous therapies such as, but not limited to, correcting electrolyte imbalances, delivering medications, transfusing blood, or replacing fluid to correct conditions such as dehydration.
- a conventional infusion bag typically contains only one solution. Further, it is not able to prevent issues of improper mixing by an administrator (such as a medical professional or pharmacy employee) due to human error. Any mixture of components must also be prepared on site, which results in a risk of contamination. This risk is much greater due to the various sites (location not being sterile) that the mixture will be prepared in.
- a conventional infusion bag also does not assure the quality of its contents, does not minimalize variance of the mixed contents (the mixer is at times inconsistent), and administration is more cumbersome because the mixture must be prepared before administering a solution to the patient.
- the present invention relates to a multi-mix infusion bag, as defined in claim 1, wherein the infusion bag has a capability to store multiple components that can be later mixed within the same bag.
- An embodiment includes a multi-mix infusion bag comprising a lower portion and an upper portion.
- the lower portion has a lower chamber.
- the upper portion comprises a plurality of chambers, wherein each chamber is separated and contains a fluid agent, and wherein the multi-mix infusion bag is configured to transfer each fluid agent within each chamber of the upper portion into the lower chamber for mixing.
- a multi-mix infusion bag comprising a separate lower portion and an upper portion.
- the lower portion may have a lower chamber.
- the upper portion may comprise four chambers, wherein each chamber is separated and contains a fluid agent in a stored condition, and wherein the multi-mix infusion bag is moveable into a dispensing condition, wherein each fluid agent within each chamber of the upper portion is transferred into the lower chamber for mixing.
- the method may comprise providing a multi-mix infusion bag having a plurality of chambers, wherein each chamber is pre-filled with a fluid agent in a stored condition; activating dispensing devices of the multi-mix infusion bag to move the multi-mix infusion bag into a dispensing condition, wherein the fluid agent in each chamber is transferred into a lower chamber; mixing the fluid agents to form a mixed fluid; and dispensing the mixed fluid to a patient.
- embodiments of the present invention relate to a multi-mix infusion bag comprising multiple agents stored separately and mixed within the infusion bag prior to dispensing.
- Embodiments of the invention can be sold pre-filled and ready to use; reduces risk of human error; reduces risk of contamination; increases ease of administration; simplifies the process of administrating infusions intravenously; protects content from oxidation; assures accurate administration; permits little to no variance between the mixtures; increases the contents shelf life; and prevents contents from reacting adversely and prematurely.
- FIGs. 1 and 3 depicts a multi-mix infusion bag 10 in a stored condition, according to embodiments.
- the multi-mix infusion bag 10 comprises an upper portion 11 and a lower portion 13.
- the lower portion 13 comprises a main chamber 12.
- the upper portion 11 comprises multiple compartments.
- the upper portion 11 may include a first chamber 40, a second chamber 41, a third chamber 42, a fourth chamber 43, a fifth chamber 44 and a sixth chamber 45.
- the multi-mix infusion bag 10 comprises chamber separating members 17, to separate fluid agents 50, 51, 52, 53, 54 and 55, wherein first fluid agent 50 is held within first chamber 40, second fluid agent 51 is held within second chamber 41, third fluid agent 52 is held within third chamber 42, fourth fluid agent 53 is held within fourth chamber 43, fifth fluid agent 54 is held within fifth chamber 44, and sixth fluid agent 55 is held within sixth chamber 45.
- the multi-mix infusion bag 10 may comprise a separating wall 18.
- the separating wall 18 separates the upper portion 11 from the lower portion 13 of the bag 10.
- the separating wall 18 serves to maintain the fluid agents 50-55 from entering lower chamber 12.
- the maintaining of the fluid agents 50-55 separate keeps the agents from reacting with one another until the appropriate time for the agents to be mixed. This increases shelf life.
- the first through sixth chambers 40-45 may each hold a predetermined amount of fluid. The separation of the fluid agents 50-55 constitutes the stored condition.
- the multi-mix infusion bag 10 comprises interior dispensing devices.
- a first dispensing device 20 corresponds to the first chamber 40
- a second dispensing device 21 corresponds to the second chamber 41
- a third dispensing device 42 corresponds to the third chamber 22
- a fourth dispensing device 23 corresponds to the fourth chamber 43
- a fifth dispensing device 24 corresponds to the fifth chamber 44
- a sixth dispensing device 25 corresponds to the sixth chamber 45.
- Each dispensing device 20-25 has a plunger and includes a perforating device.
- the first dispensing device 20 may include a first perforating device 30, the second dispensing device 21 may include a second perforating device 31, the third dispensing device 22 may include a third perforating device 32, the fourth dispensing device 23 may include a fourth perforating device 33, the fifth dispensing device 24 may include a fifth perforating device 34, and the sixth dispensing device 25 may include a sixth perforating device 35.
- the dispensing devices 20-25 are in a stored position, wherein the fluid agents 50-55 are maintained in a separated condition.
- the multi-mix infusion bag 10 may further include a dispensing bar 16, wherein the dispensing bar 16 couples the dispensing devices 20-25 together such that the dispensing bar 16 may be moved in a direction toward the lower portion 13 of the bag 10. Moving the dispensing bar 16 in the direction toward the lower portion 13 results in simultaneously activating each dispensing device 20-25 and moving each into a dispensing position. Accordingly, it should be understood that in some embodiments each dispensing device 20-25 may be activated independently, and in other embodiments, the dispensing devices 20-25 may be activated simultaneously.
- FIG. 2 depicts the multi-mix infusion bag 10 in a mixing condition according to embodiments.
- the dispensing devices 20-25 are shown in the dispensing position. When in the dispensing position, the dispensing devices 20-25 are each depressed toward the lower portion 13 of the bag 10.
- plungers of each of the dispensing devices 20-25 are depressed toward the lower portion 13 of the bag 10 so that the point 92 of the needles 30-35 pierce the separating wall 18.
- the plungers may be depressed individually or may be depressed by applying pressure to the dispensing bar 16 which simultaneously forces all of the plungers into a depressed position.
- the needles 30-35 When depressed, the needles 30-35 have each pierced the separating wall 18.
- the needles 30-35 may each be a conduit, wherein the fluid agents 50-55 flow through the needles 30-35 respectively and enter into the lower chamber 12.
- Outlet 60 is configured to couple to known tubing for intravenously dispensing the mixed fluid 70 to a patient.
- Inlet 62 operates to allow the additional additives to enter the lower chamber 12 and be mixed with the mixed fluid 70.
- hanger 64 may operate to operatively couple the bag 10 to a hanging device typically used to elevate infusion bags.
- the lower chamber may be a size to hold at least the combined amount of fluid of the upper chambers.
- dispensing devices 20-25 include a plunger which may be the top portion of the dispensing devices 20-25.
- the plunger allows the dispensing devices 20-25 to be forced into a depressed or engaged location wherein the dispensing devices 20-25 are activated, allowing the fluid agents 50-55 to flow into the lower chamber 12 of the bag 10.
- dispensing devices 20-25 may include lip portion 90, wherein the lip portion 90 of each dispensing device 20-25 may engaged projections of a tube engagement with each upper chamber 40-45.
- the lip 90 inhibits removal of dispensing devices 20-25 once they are engaged within the tubes of the chambers 40-45.
- perforating devices 30-35 have various embodiments that are contemplated, such as, but not limited to a needle, a conduit and the like.
- each perforating device 30-35 includes a point 92 for puncturing the separation wall 18.
- Each perforating device 30-35 may also include a channel 94 wherein once the perforating device 30-35 punctures the separation wall 18.
- Channel 94 creates a fluid channel between upper chambers 40-45 and lower chamber 12. Fluid can then flow by gravity from the upper chambers 40-45 to the lower chamber 12.
- Other embodiments of needles 30-35 include a point 92 and a conduit perforating device having perforations 96 to allow fluid to enter the conduit portion and flow through an opening at the point 92. Fluid can them flow by gravity from the upper chambers 40-45 to the lower chamber 12. It will be understood that other types of needles may be used so long as a fluid communication between each of the upper chambers 40-45 and the lower chamber 12 is formed.
- the multi-mix infusion bag 110 comprises an upper portion 111 and a lower portion 113.
- the lower portion 113 comprises a main chamber 112.
- the upper portion 111 may comprise multiple compartments.
- the upper portion 111 may include a first chamber 140, a second chamber 141, a third chamber 142, a fourth chamber 143, a fifth chamber 144 and a sixth chamber 145.
- the multi-mix infusion bag 110 comprises chamber separating members 117, to separate fluid agents 150, 151, 152, 153, 154 and 155, wherein first fluid agent 150 is held within first chamber 140, second fluid agent 151 is held within second chamber 141, third fluid agent 152 is held within third chamber 142, fourth fluid agent 153 is held within fourth chamber 143, fifth fluid agent 154 is held within fifth chamber 144, and sixth fluid agent 155 is held within sixth chamber 145.
- the multi-mix infusion bag 110 may comprise a separating wall 118.
- the separating wall 118 separates the upper portion 111 from the lower portion 113 of the bag 110.
- the separating wall 118 serves to maintain the fluid agents 150-155 from entering lower chamber 112.
- the maintaining of the fluid agents 150-155 separate keeps the agents from reacting with one another until the appropriate time for the agents to be mixed. This increases shelf life.
- the first through sixth chambers 140-145 may each hold a predetermined amount of fluid. The separation of the fluid agents 150-155 constitutes the stored condition.
- FIG. 5B depicts the multi-mix infusion bag 110 in a mixing condition
- the upper chambers 140-145 are shown in a dispensing position, wherein pressure is applied to each upper chamber 140-145 to form a perforation in separating wall 118.
- the perforations in the separating wall 118 allow for the fluid agents 150-155 to flow through the perforations and enter into the lower chamber 112.
- the fluid agents 150-155 are mixed together to form a mixed fluid 170 ready to be dispensed through outlet 160.
- Outlet 160 is configured to couple to known tubing for intravenously dispensing the mixed fluid 170 to a patient. During operation, it may be necessary to mix additional additives into the mixed fluid 170.
- Inlet 162 operates to allow the additional additives to enter the lower chamber 112 and be mixed with the mixed fluid 170. Further, hanger 164 may operate to operatively couple the bag 110 to a hanging device typically used to elevate infusion bags.
- the lower chamber 112 may be a size to hold at least the combined amount of fluid of the upper chambers 140-145.
- the multi-mix infusion bag 210 comprises an upper portion 211 and a lower portion 213, wherein the upper portion 211 is separate from the lower portion 213.
- the lower portion 213 comprises a main chamber 212.
- the upper portion 211 may comprise multiple compartments, wherein the upper portion 211 may be coupled to the lower portion 213 in order to form a complete multi-mix infusion bag 210.
- the upper portion 211 may include a first chamber 240, a second chamber 241, a third chamber 242, and a fourth chamber 243.
- the multi-mix infusion bag 210 comprises chamber separating members 217, to separate fluid agents held within each upper chamber 240-243.
- Each upper chamber 240-243 comprises an outlet portion 280, through which the separate fluid agents are dispensed.
- FIG. 6B depicts the multi-mix infusion bag 210 in a connected condition
- the upper portion 211 includes a first connecting member 290 and the lower portion 213 includes a second connecting member 292.
- the first connecting member 290 may engaged the second connecting member 292 in order to couple the upper portion 211 to the lower portion 213.
- the first connecting member 290 may be a tongue with pawls and the second connecting member 292 may be a groove receiver. It is understood that other connecting devices may be utilized, so long as the upper portion 211 is coupled to the lower portion 213.
- the upper chambers 240-243 are shown with outlet ports 280 engaging inlet ports 282 and a separating wall 218 is formed.
- the separated fluid agents may be transferred from the upper chambers 240-243 to the lower chamber 212 through the outlet ports 280 and inlet ports 282 by means previously described in FIGs. 1-3 and 5A-5B .
- Inlet 262 operates to allow the additional additives to enter the lower chamber 212 and be mixed with the mixed fluid 170.
- hanger 264 may operate to operatively couple the bag 210 to a hanging device typically used to elevate infusion bags.
- each upper chamber 240-243 may hold a predetermined amount of fluid
- the lower chamber 212 may be a size to hold at least the combined amount of fluid of the upper chambers 240-243.
- the multi-mix infusion bag comprises six chambers and FIGs 6A-6B show 4 upper chambers, some embodiments may include two chambers, three chambers, four chambers, five chambers, six chambers, seven chambers, eight chambers or more. It may be contemplated that any number of chambers may be utilized in a multi-mix infusion bag.
- the multi-mix infusion bag may be amber in color and therefore impedes light and oxidation.
- the bag may be formed of silicone that is latex free, pvc free and DEHP free.
- FIG. 7 depicts a flow chart showing a method 80 of using a multi-mix infusion bag according to embodiments.
- the method 80 may include providing a multi-mix infusion bag having a plurality of chambers, wherein each chamber is pre-filled with a fluid agent (Step 81).
- the method may then include activating dispensing devices of the multi-mix infusion bag, wherein the fluid agent in each chamber is transferred into a lower chamber for mixing (Step 82).
- the fluid is then mixed (Step 83). Once the fluid is mixed, the method 80 includes dispensing the mixed fluid to a patient.
- Step 82 of activating the dispensing devices may include independently activating each dispensing device. In other embodiments, activating the dispensing devices may include simultaneously activating all of the dispensing devices.
- the method 80 may further include transferring an additive to the mixed fluid through an inlet of the multi-mix infusion bag.
- the method may also include impeding light and oxidation.
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Fluid Mechanics (AREA)
- Physics & Mathematics (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Package Specialized In Special Use (AREA)
Claims (4)
- Poche de perfusion à plusieurs mélanges comprenant :une partie inférieure (13) ayant une chambre inférieure ; etune partie supérieure comprenant une pluralité de chambres, dans laquelle chaque chambre est séparée et contient un agent fluide (50-55), et dans laquelle la poche de perfusion à plusieurs mélanges est configurée pour transférer chaque agent fluide (50-55) dans chaque chambre de la partie supérieure dans la chambre inférieure pour mélange, comprenant un mécanisme de distribution associé à chaque chambre de la partie supérieure, et chaque mécanisme de distribution comprend un dispositif de distribution (20-25), et dans laquelle chaque agent fluide (50-55) est transféré de chacune de la pluralité de chambres dans la chambre inférieure en réponse à l'activation du mécanisme de distribution, et dans laquelle chaque dispositif de distribution (20-25) a un piston plongeur et comprend un dispositif de perforation, comprenant une aiguille (30-35) et un conduit de dispositif de perforation, dans laquelle l'activation du mécanisme de distribution comprend l'enfoncement du dispositif de distribution vers la partie inférieure (13) de la poche (10), de sorte que, afin de distribuer les agents fluides (50-55) dans la partie inférieure (13) de la poche (10), les pistons plongeurs de chacun des dispositifs de distribution (20-25) sont enfoncés vers la partie inférieure (13) de la poche (10) de sorte qu'une pointe (92) des aiguilles (30-35) perce une paroi de séparation (18), la poche comprenant des éléments de séparation situés entre chacune de la pluralité de chambres.
- Poche (10) selon la revendication 1 ou 2, dans laquelle la paroi de séparation (18) est située entre la partie supérieure et la partie inférieure de la poche de perfusion à plusieurs mélanges (10).
- Poche (10) selon au moins l'une des revendications précédentes, dans laquelle le conduit de dispositif de perforation perce la paroi de séparation (18) en réponse à l'enfoncement du dispositif de distribution.
- Poche (10) selon au moins l'une des revendications précédentes, comprenant en outre une barre de distribution couplant chacun des dispositifs de distribution (20-25) ensemble, dans laquelle la barre de distribution fonctionne pour enfoncer chaque dispositif de distribution simultanément.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462026171P | 2014-07-18 | 2014-07-18 | |
PCT/US2015/041178 WO2016011450A1 (fr) | 2014-07-18 | 2015-07-20 | Sac de perfusion multi-mélange |
Publications (3)
Publication Number | Publication Date |
---|---|
EP3169300A1 EP3169300A1 (fr) | 2017-05-24 |
EP3169300A4 EP3169300A4 (fr) | 2018-03-14 |
EP3169300B1 true EP3169300B1 (fr) | 2022-02-16 |
Family
ID=55073681
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP15821255.5A Active EP3169300B1 (fr) | 2014-07-18 | 2015-07-20 | Sac de perfusion multi-mélange |
Country Status (8)
Country | Link |
---|---|
US (3) | US10500133B2 (fr) |
EP (1) | EP3169300B1 (fr) |
KR (1) | KR20170039686A (fr) |
BR (1) | BR112017001123B1 (fr) |
ES (1) | ES2908055T3 (fr) |
MX (1) | MX2017000854A (fr) |
SG (2) | SG11201700414QA (fr) |
WO (1) | WO2016011450A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
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JP6993965B2 (ja) * | 2015-06-19 | 2022-01-14 | 武田薬品工業株式会社 | 単一または複数の容器のための貯留デバイス |
US11903900B2 (en) | 2018-10-03 | 2024-02-20 | Takeda Pharmaceutical Company Limited | Packaging for multiple containers |
TWI680754B (zh) * | 2019-01-31 | 2020-01-01 | 林忠信 | 雙層式醫療用液袋 |
CN111468423B (zh) * | 2020-04-15 | 2022-01-18 | 台州柏恩利自动化设备有限公司 | 一种输液器检测用分管机 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ3869U1 (cs) * | 1990-11-07 | 1995-09-26 | Otsuka Pharmaceutical Factory, Inc. | Zásobník s větším počtem komor |
US6135632A (en) * | 1999-06-16 | 2000-10-24 | Flint; Theodore R. | Disposable static mixing device having check valve flaps |
JP2002248158A (ja) * | 2000-10-13 | 2002-09-03 | Material Eng Tech Lab Inc | 収容物入り医療用容器及びそれに適した容器 |
ITMI20020516A1 (it) * | 2002-03-12 | 2003-09-12 | Gambro Lundia Ab | Liquidi per dialisi peritoneale emodialisi e reintegrazione |
EP1560622B1 (fr) | 2002-07-09 | 2008-03-05 | Carmel Pharma AB | Dispositif d'injection des substances medicales |
US9334098B1 (en) * | 2004-03-26 | 2016-05-10 | Kenneth D. Hughes | Reactive materials packaging |
DE602005021355D1 (de) * | 2004-05-28 | 2010-07-01 | Ajinomoto Kk | Abgedichteter lagerungsbeutel mit mehrfachkammerstruktur |
CN201840664U (zh) * | 2010-09-30 | 2011-05-25 | 杨怀梅 | 输液袋配药用支撑装置 |
CN103800199A (zh) * | 2014-03-06 | 2014-05-21 | 容家杨 | 一种棕色磨砂表面输液袋 |
EP4054509B1 (fr) | 2019-11-08 | 2024-01-17 | Bristol-Myers Squibb Company | Chemin fluidique alternatif pour modules de médicament pouvant être connectés en série |
-
2015
- 2015-07-20 MX MX2017000854A patent/MX2017000854A/es unknown
- 2015-07-20 US US14/804,071 patent/US10500133B2/en active Active
- 2015-07-20 EP EP15821255.5A patent/EP3169300B1/fr active Active
- 2015-07-20 WO PCT/US2015/041178 patent/WO2016011450A1/fr active Application Filing
- 2015-07-20 SG SG11201700414QA patent/SG11201700414QA/en unknown
- 2015-07-20 SG SG10201912427VA patent/SG10201912427VA/en unknown
- 2015-07-20 BR BR112017001123-9A patent/BR112017001123B1/pt active IP Right Grant
- 2015-07-20 ES ES15821255T patent/ES2908055T3/es active Active
- 2015-07-20 KR KR1020177004460A patent/KR20170039686A/ko not_active Application Discontinuation
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2019
- 2019-12-09 US US16/707,211 patent/US11712402B2/en active Active
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2023
- 2023-08-01 US US18/363,553 patent/US20230404851A1/en active Pending
Non-Patent Citations (1)
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US20160015889A1 (en) | 2016-01-21 |
EP3169300A1 (fr) | 2017-05-24 |
ES2908055T3 (es) | 2022-04-27 |
BR112017001123B1 (pt) | 2023-12-19 |
US20200113782A1 (en) | 2020-04-16 |
SG10201912427VA (en) | 2020-02-27 |
SG11201700414QA (en) | 2017-02-27 |
EP3169300A4 (fr) | 2018-03-14 |
KR20170039686A (ko) | 2017-04-11 |
BR112017001123A2 (pt) | 2018-01-23 |
MX2017000854A (es) | 2017-05-04 |
US11712402B2 (en) | 2023-08-01 |
US10500133B2 (en) | 2019-12-10 |
US20230404851A1 (en) | 2023-12-21 |
WO2016011450A1 (fr) | 2016-01-21 |
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