EP3166565B1 - Detection unit for detecting the removal of medicines - Google Patents
Detection unit for detecting the removal of medicines Download PDFInfo
- Publication number
- EP3166565B1 EP3166565B1 EP15741715.5A EP15741715A EP3166565B1 EP 3166565 B1 EP3166565 B1 EP 3166565B1 EP 15741715 A EP15741715 A EP 15741715A EP 3166565 B1 EP3166565 B1 EP 3166565B1
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- EP
- European Patent Office
- Prior art keywords
- carrier layer
- electrode
- electrodes
- carrier
- detection unit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 238000001514 detection method Methods 0.000 title claims description 130
- 239000003814 drug Substances 0.000 title claims description 95
- 229940079593 drug Drugs 0.000 title claims description 70
- 238000004806 packaging method and process Methods 0.000 claims description 21
- 239000011888 foil Substances 0.000 claims description 19
- 238000005259 measurement Methods 0.000 claims description 8
- 239000003990 capacitor Substances 0.000 claims description 6
- 230000002093 peripheral effect Effects 0.000 claims description 3
- 239000000969 carrier Substances 0.000 claims description 2
- 239000010410 layer Substances 0.000 description 132
- 230000037406 food intake Effects 0.000 description 2
- 230000006641 stabilisation Effects 0.000 description 2
- 238000011105 stabilization Methods 0.000 description 2
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 239000012790 adhesive layer Substances 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 231100000517 death Toxicity 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000005283 ground state Effects 0.000 description 1
- 239000011229 interlayer Substances 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000012811 non-conductive material Substances 0.000 description 1
- 238000011369 optimal treatment Methods 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- 239000005538 withdrawn drug Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
- A61J1/035—Blister-type containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J2200/00—General characteristics or adaptations
- A61J2200/30—Compliance analysis for taking medication
Definitions
- the invention relates to a detection unit for detecting the withdrawal of medicaments, such as tablets, capsules or the like, from a packaging which has at least one pocket for medicaments. Furthermore, the invention relates to a unit comprising a plurality of detection units according to claim 9. Furthermore, the invention relates to a packaging unit according to claim 12. Finally, the invention relates to a drug blister assembly according to claim 13.
- WO 89/09042 discloses a detection unit for detecting the withdrawal of drugs from a packaging unit comprising at least one pocket for a drug, the pocket having an opening which is closed by a foil, the detection unit having a first carrier layer with a contact surface for engaging the foil of the packaging unit wherein a first flat electrode is arranged on the first carrier layer, a second carrier layer adjoining the first carrier layer is arranged parallel to the first carrier layer and the first electrode, and a first perforation is provided in the first carrier layer, and a second perforation is provided in the second carrier layer second perforation is provided.
- the object of the invention is therefore to provide a detection unit for the detection and ingestion of drugs, which is inexpensive to implement and works effectively and reliably.
- the invention solves this in a detection unit of the type mentioned above with the characterizing features of claim 1.
- the invention relates to a detection unit for detecting the withdrawal of medicaments from a packaging unit having at least one pocket for a medicament, wherein the bag has an opening which is closed by a film.
- An essential advantage of the invention is that the detection of the withdrawal of drugs from the bag is possible without additional measures by the patient and the detection unit is at the same time very simple and the removal and ingestion of the drug little affected. In addition, the detection of the removal of a drug is reliably feasible.
- a particularly simple development in which the removal can be achieved by means of conductivity measurement, provides that the first electrode and the second electrode are arranged between the two carrier layers, wherein the two electrodes abut each other and thus form a conductive contact.
- An embodiment which allows a capacitive detection of the removal of the drug, provides that the first electrode and the second electrode are arranged between the two carrier layers, wherein the two electrodes are separated by an insulating intermediate layer and thus form a capacitor.
- the first electrode is arranged on the contact surface of the first carrier layer and the second electrode is arranged on the side of the second carrier layer facing the first carrier layer is arranged, optionally on the first electrode, an insulating intermediate layer is arranged.
- a further detection unit which detects the removal of medicaments capacitively, provides that the first electrode is arranged on the side of the first carrier layer facing away from the contact surface and the second electrode is arranged on the side of the second carrier layer facing away from the first carrier layer.
- a mechanically stable arrangement can be achieved by providing a third carrier layer adjacent to the second carrier layer for stiffening the detection unit, and providing in the third carrier layer a recess through which the tablet can pass and keep the areas of the carrier layers carrying the electrodes free.
- a particularly simple removal of the tablets and a reliable detection of the removal can be ensured by the perforations in the carrier layers are partially congruent to each other.
- the electrodes located on the carrier layers congruently abut each other or face each other.
- a particularly preferred variant for making electrical contact with the electrodes and for forming the perforation to enable an advantageous folding away of the carrier parts carrying the electrodes during removal provides that the perforation respectively arranged on the first and / or the second carrier layer partially surrounds the respective electrode, and on both Träfordn each a non-perforated web is provided, with which the respective electrode carrying the region of the carrier layer is connected to the remaining region of the carrier layer.
- a folding away of the electrodes, which causes a rapid and permanent capacitive change, can be achieved by the two webs opposite each other in the peripheral region of the electrodes.
- An advantageous contacting of the electrodes provides that the respective electrode is electrically conductively connected to a line extending over the web on the carrier layer.
- Electrodes are each electrically conductively connected, in particular via the line, to a measuring device, the measuring device determining the respective capacitance or the conductance between the two electrodes.
- the invention relates to a detection arrangement comprising a multiplicity of detection units according to the invention, wherein the detection units each have a common first and second carrier layer and a common contact surface.
- This detection arrangement allows a particularly simple embodiment of a plurality of detection units in a common body, in particular for detecting the removal of a plurality of drugs from the pockets of a drug blister.
- all the first electrodes are connected to one another in a conductive manner via a first common line and all second electrodes are connected to one another in a conductive manner via a second common line and a common measuring device is provided, which switches the respective capacitance or the conductance between the first and the second line determined.
- Fig. 1 shows a packaging unit comprising an embodiment of a detection unit according to the invention and a closed by a film bag for pharmaceuticals.
- Fig. 2 shows a carrier layer of the in Fig. 1 shown detection unit.
- Fig. 3 shows the arrangement of the individual elements on the carrier layers in the in Fig. 1 and Fig. 2 shown detection unit.
- Fig. 4 shows the in Fig. 1 shown detection unit after removal of the tablet.
- Fig. 5 shows the detection unit of Fig. 4 in an oblique view.
- the Fig. 6 to 9 show alternative embodiments of detection units.
- Fig. 6 shows a detection unit with a capacitive arrangement for detecting the removal, wherein the electrodes lie between the carrier layers.
- Fig. 6 shows a detection unit with a capacitive arrangement for detecting the removal, wherein the electrodes lie between the carrier layers.
- FIG. 7 shows a detection unit with a capacitive arrangement for detecting the removal, wherein the electrodes abut against the second carrier layer.
- Fig. 8 shows a detection unit with a capacitive arrangement for detecting the removal, wherein the electrodes abut against the first carrier layer.
- Fig. 9 shows a detection unit according to Fig. 7 with a stiffening serving third carrier layer.
- Fig. 10 shows a detection arrangement with a plurality of detection units, wherein the detection of the tablet removal in the individual detection units as in in Fig. 1 formed detection unit is formed.
- Fig. 11 shows one Detection arrangement with a plurality of detection units, wherein the detection of the tablet removal in the individual detection units as in in Fig. 6 formed detection unit is formed.
- Fig. 12 shows a detection arrangement with a plurality of detection units, wherein the detection of the tablet removal in the individual detection units as in in Fig. 7 formed detection unit is formed.
- Fig. 13 shows a detection arrangement with a plurality of detection units, wherein the detection of the tablet removal in the individual detection units as in in Fig. 8 formed detection unit is formed.
- Fig. 14 shows a detection arrangement with a plurality of detection units, wherein the detection of the tablet removal in the individual detection units as in in Fig. 9 formed detection unit is formed.
- Fig. 15 shows a drug blister.
- Fig. 16 shows a first carrier layer for detecting the removal of tablets from the in Fig. 15 illustrated blister.
- Fig. 17 shows a second carrier layer for detecting the removal of tablets from the in Fig. 15 illustrated blister.
- Fig. 18 shows an alternative to the in Fig. 16 illustrated embodiment of a first carrier layer.
- Fig. 19 shows an alternative to the in Fig. 17 illustrated embodiment of a second carrier layer.
- Fig. 20 is schematically the course of the capacity for piecewise withdrawal of drugs from the drug blister from the FIGS. 18 and 19 shown.
- Fig. 21 shows an alternative embodiment of a detection arrangement in which the first and the second carrier layer are arranged on the same, folded carrier.
- Fig. 22 shows an embodiment of a drug blister in section with the in Fig. 21 illustrated detection arrangement.
- a drug package 200 is shown containing a drug 201 which is inserted into a pocket 202 and is closed by a foil 204.
- the drug 201 is pressed through an opening 203 in the base body 205, so that the film breaks 204 and the drug 201 can be removed.
- the 1 illustrated packaging unit 300 further comprises a detection unit 100 which rests flat over a contact surface 199 on the film 204 of the drug package 200.
- the detection unit 100 has two carrier layers 110, 120, which are made of non-conductive material. In the present embodiment, it may be, for example, cardboard, paper or plastic.
- the first carrier layer 110 forms the contact surface 199 for contact with the foil 204 of the packaging unit 200.
- a first electrode 111 is arranged on the side facing away from the film 204 of the carrier layer 110.
- the first electrode 111 lies in the region of the opening 203 and covers the opening 203.
- a second carrier layer 120 is arranged.
- first carrier layer 110 wherein optionally may form between the two carrier layers 110, 120 due to the protruding electrodes 111, 121 gap regions.
- second, flat electrode 121 is arranged, which is opposite to the first electrode 111 and abuts against this.
- first electrode 111 and the second electrode 121 between the two support layers 110, 120 are arranged.
- the two electrodes 111, 121 abut each other, whereby a conductive contact between these two electrodes 111, 121 is formed.
- both the first and the second carrier layer 110, 120 each have a perforation 112, 122.
- the first and second perforations 112, 122 surround the electrode 111, 121.
- the electrode 111, 121 is connected to a line 113, 123 extending on or in the carrier layer 110, 120, which connects the electrode 111, 121 to a not shown Meter connects.
- the respective region of the carrier layer 110, 120 carrying the electrode 111, 121 is connected via the web 114, 124 to the remaining region of the carrier layer 110, 120.
- a non-perforated web 114, 124 is provided in the peripheral region of the electrodes 111, 121, over which the respective line 113, 123 extends.
- the perforations 112, 122 are partially congruent in the carrier layers.
- the electrodes 111, 121 are congruent to each other or to each other.
- Fig. 3 shows a concrete arrangement of the two carrier layers 110, 120 to each other, wherein the two carrier layers 110, 120 are shown spaced from each other.
- the two electrodes 111, 121 lie one above the other opaque.
- the webs 114, 124 face each other as viewed from the electrodes 111, 121.
- the lines 113, 123 open from the respective electrode 111, 121 via the respective webs 114, 124 in different directions.
- Fig. 4 the packaging unit 300 comprising the packaging 200 as well as the detection unit 100 after removal of the medicament 201 from the pocket 202 are shown.
- the removal of the medicament 201 from the packaging unit 200 ruptures the foil 204 so that the medicament 201 can escape.
- the detection unit 100 abutting on the packaging unit 200 is likewise changed by the removal of the medicament 201, the medicament 201 being pushed through the two carrier layers 110, 120, since the perforations 112, 122 rupture due to the pressure exerted by the patient or withdrawing person and the medicament 201 can pass through the openings thus formed.
- the two electrodes 111, 121 or the regions of the carrier layers 110, 120 on which the electrodes 111, 121 rest are pivoted away from different articulation points or articulation regions in the region of the webs 114, 124, whereby a Aperture through which the drug 201 passes and can be removed.
- the two electrodes 111, 121 are removed from one another, so that in the present case the electrical contact, formed in the ground state, between these two electrodes 111, 121 is interrupted.
- Fig. 5 the detection unit 100 is shown after removal of the drug 201, as seen from the second carrier layer 120. It can be seen that the two electrodes 111, 121 are folded away from their initial position to different spatial directions and have away from each other.
- a packaging unit 300 is shown with an alternative embodiment of a detection unit 100, wherein in this detection unit 100 instead of a conductivity measurement for detecting the removal, a capacitive measurement is provided.
- the first electrode 111 and the second electrode 121 are arranged between the two carrier layers 110, 120.
- insulating intermediate layer 130 which the electrodes 111, 121 against each other. Due to the insulating intermediate layer 130, the two electrodes 111, 121 stand not in electrically conductive contact with each other, but it forms a measurable capacity between them.
- this capacitance decreases correspondingly.
- the two carrier layers 110, 120 it is not necessary for the two carrier layers 110, 120 to surround the two electrodes 111, 121.
- the electrodes 111, 121 it is also possible for the electrodes 111, 121 to lie opposite one another on one of the two carrier layers 110, 120.
- Figure 7 a further embodiment of the invention is shown, in which the first electrode 111 is disposed on the side facing away from the contact surface 199 of the first carrier layer 110 and the second electrode 121 is disposed on the side facing away from the first carrier layer 110 side of the second carrier layer 120.
- the two electrodes 111, 121 face each other on the first carrier layer 110.
- the first electrode 111 is arranged on the contact surface 199 of the first carrier layer 110
- the second electrode 121 is arranged on the side of the second carrier layer 120 facing the first carrier layer 110.
- an insulating intermediate layer 140 disposed on the first electrode 111. This insulating interlayer 140 prevents conductive contact between the first electrode 111 and the film 204. In particular, in the event that the film 204 is not conductive, an insulating intermediate layer 140 may also be omitted.
- the contact surface 199 of the detection unit 100 facing the packaging unit 200 is coated with an adhesive layer with which the detection unit 100 adheres to the packaging unit 200.
- a further embodiment of the invention is shown, which is substantially the in Fig. 7 illustrated embodiment, in its lower region, however, still another carrier layer 150 which serves for the mechanical stabilization of the detection unit 100.
- the third carrier layer 150 a recess 151 is provided, through which the tablet can pass and through which the electrodes 111, 121 carrying portions of the carrier layers 110, 120 can swing out when pressed through the drug 201.
- the electrodes have a layer thickness of about 5 to 100 microns.
- the carrier layers 110, 120 have a layer thickness in the range of approximately 100 to 500 ⁇ m. In the Fig. 9 illustrated further carrier layer 150 has a layer thickness of about 500 microns.
- detection arrangements 400 comprising a plurality of detection units 400a, 400b shown.
- the in the 10 to 14 individually illustrated detection units 400a, 400b are constructed the same as those in the Fig. 1 . 6 . 7, 8 and 9 Detection units shown, each of the detection arrangements shown each having a plurality of these detection units 400a, 400b.
- the detection units 400a, 400b each have a common first carrier layer 410 and a common second carrier layer 420.
- First electrodes 411a, 411b and first perforations 412a, 412b are respectively arranged on the common first carrier layer 410 for each of the detection units 400a, 400b.
- second electrodes 421a, 421b and second perforations 422a, 422b are respectively arranged for each of the detection units 400a, 400b.
- drug blister assembly 600 includes in addition to the detection arrangement 400 and a drug blister 500.
- the drug blister 500 has a number of pockets 502a, 502b, in each of which a drug 501a, 501b is inserted.
- the pockets 502a, 502b each have an opening 503a, 503b which is closed by a common foil 504.
- the individual pockets 502a, 502b are formed in a common main body 505.
- the detection arrangement 400 has a contact surface 499 against which the detection arrangement rests against the medicament blister 500.
- a respective capacitor is formed for each detection unit 400a, 400b of the detection arrangement 400, with which the removal of the respective drug 501a, 501b from the respective pocket 502a, 502b can be detected.
- an insulating intermediate layer common to the entire detection arrangement. This may be either perforated to allow passage of the drugs 501a, 501b or to be easily disrupted.
- FIG. 3 is a section through one embodiment of a detection arrangement in which the individual detection units 400a, 400b are as shown in FIG Fig. 7 is trained.
- insulating intermediate layers 440a, 440b are provided for each first electrode 411a, 411b which isolates the first electrodes 411a, 411b from the possibly conductive common foil 504 of the drug blister 500.
- an insulating intermediate layer common to the entire detection arrangement This may be either perforated to allow passage of the drugs 501a, 501b or to be easily disrupted.
- a further preferred embodiment of a detection arrangement 400 is shown, which is substantially the in Fig. 12 executed embodiment corresponds.
- a third carrier layer 450 which serves for the mechanical stabilization of the detection arrangement.
- This third carrier layer 450 is common to all the detection units 400a, 400b arranged on the detection arrangement 400.
- a separate recess 451a, 451b is provided, through which the drug 501a, 501b can pass, and areas of the carrier layers 410, 420 carrying the medicaments 501a, 501b, which carry the electrodes 411a, 411b, 421a, 421b can swing out.
- the respective second electrode 421a, 421b is in each case electrically conductively connected to a line 423a, 423b.
- the line is led to a contact 481a, 481b which is located on a contact region 480 of the second carrier layer 420.
- the removal of the drug 201, 501a, 501b can be determined in each case by determining the conductivity or the capacitance between the two electrodes 111, 121, 411a, 411b, 421a, 421b. If a plurality of electrodes 411a, 411b, 421a, 421b are arranged on a common carrier 410, 420, the capacitance between the opposing electrodes 411a, 421a; 411b, 421b determined. It is possible for each pair of opposing electrodes forming a capacitor to have its own measuring device for capacitance measurement, or for the individual connections to be connected to the terminals of the measuring device via two selection circuits, in particular multiplexers.
- a first carrier layer is shown, which differs from the first carrier layer of Fig. 16 differs in that instead of individual lines 413a, 413b to the Electrodes only a common line connected to all electrodes 413 is provided.
- second support layer 420 instead of individual first lines 423a, 423b to the electrodes only a common second electrode 423 connected to all electrodes provided.
- Fig. 20 It is shown how the detection of the withdrawal of drugs 501a, 501b from a drug arrangement 600 with the in FIGS. 18 and 19 shown carrier layers 410, 420 accomplish. If no drugs 501a, 501b have yet been removed, a very high capacity can be determined due to the parallel connection of the individual capacitors formed by the electrodes 411a, 411b. By removing a drug 501a, 501b from the drug blister 500, the capacity of the condenser formed by the electrodes 411a, 411b is changed.
- a measurement can be carried out in such a way that a capacitance measurement is carried out at predetermined, in particular periodic time intervals and, in the event that the capacitance changes by a value exceeding a predetermined threshold value, a tablet removal is considered to be detected and an advance on the number of tablets
- the value set in drug blister 500 is reduced by 1 in each case.
- FIG. 21 another embodiment of a detection arrangement 400 is shown in which the first and the second carrier layer 410, 420 are on the same, folded carrier.
- the carrier has three partial regions 410, 460, 420 separated by folding regions 490.
- the first subregion forms the first carrier layer 410.
- the adjoining second partial region 460 extends on the side facing away from the first carrier layer 410 and has recesses 461a, 461b for the passage of pockets of a medicament blister 500.
- the second subregion 460 is adjoined by a third subregion, which forms the second carrier layer 420 and which is connected or connectable to the first subregion forming the first carrier layer 410.
- Fig. 22 is shown folded out of the carrier detection arrangement 400.
- the detection arrangement 400 shown here essentially corresponds to that in FIG Fig. 10 illustrated detection arrangement 400, wherein of course it is also possible to arrange the first and second carrier layer 420 of the other illustrated embodiments on the same, folded carrier. How out Fig. 22 As can be seen, the recesses 461a, 461b are placed on the pockets 502a, 502b so that the pockets 502a, 502b pass through the recesses 461a, 461b.
Description
Die Erfindung betrifft eine Detektionseinheit zur Detektion der Entnahme von Arzneimitteln, wie beispielsweise Tabletten, Kapseln o.ä., aus einer Verpackung, die zumindest eine Tasche für Arzneimittel aufweist. Weiters betrifft die Erfindung eine Einheit umfassend eine Vielzahl von Detektionseinheiten gemäß dem Patentanspruch 9. Weiters betrifft die Erfindung eine Verpackungseinheit gemäß Patentanspruch 12. Schließlich betrifft die Erfindung eine Arzneimittelblisteranordnung gemäß Patentanspruch 13.The invention relates to a detection unit for detecting the withdrawal of medicaments, such as tablets, capsules or the like, from a packaging which has at least one pocket for medicaments. Furthermore, the invention relates to a unit comprising a plurality of detection units according to
Hintergrund der Erfindung ist die Kontrolle der korrekten Einnahme von Medikamenten. Selbst bei richtiger Diagnose und optimalem Therapieplan kann der Therapieerfolg drastisch reduziert sein, wenn der Patient das Arzneimittel nicht richtig anwendet. Bei manchen Medikamenten, wie beispielsweise bei Blutgerinnungshemmern kann eine falsche Anwendung sogar lebensbedrohliche Folgen haben. Die Fehlerquellen in der Praxis sind durchaus vielfältig: Patienten nehmen oft keine oder die falschen Medikamente oder sie nehmen die richtigen Medikamente in zu kleinen oder zu hohen Dosen. Nach Schätzungen der WHO hält sich jeder zweite Patient nicht an den Beipackzettel oder an die ärztlichen Anweisungen. Experten gehen davon aus, dass eine Vielzahl von Todesfällen, insbesondere bei Herz-Kreislauf-Erkrankungen, auf eine falsche Anwendung von Medikamenten zurückzuführen ist.Background of the invention is the control of the correct intake of drugs. Even with the right diagnosis and optimal treatment plan, treatment success can be drastically reduced if the patient does not use the medicine properly. For some medications, such as anticoagulants, a wrong application can even have life-threatening consequences. The sources of error in practice are quite diverse: Patients often take no or the wrong drugs or they take the right medication in too small or too high doses. According to WHO estimates, every second patient does not follow the instruction leaflet or the doctor's instructions. Experts believe that a variety of deaths, especially in cardiovascular diseases, is due to a misuse of drugs.
Aus diesen Gründen ist eine zuverlässige Erfassung der korrekten und regelmäßigen Medikamenteneinnahme wünschenswert. Eine solche Kontrolle der Medikamenteneinnahme ist aus dem Stand der Technik bekannt, jedoch in vielen Fällen nur mit teuren Komponenten und großem Aufwand zu erreichen. Dies hat zur Folge, dass eine Überwachung der Einnahme nur für sehr teure Medikamente überhaupt sinnvoll ist. Für preisgünstigere Medikamente stellt eine aufwändige Elektronik zur Erfassung der Einnahme mitunter eine unwirtschaftliche Erhöhung der Kosten dar.
Die Erfindung betrifft eine Detektionseinheit zur Detektion der Entnahme von Arzneimitteln aus einer zumindest eine Tasche für ein Arzneimittel aufweisenden Verpackungseinheit , wobei die Tasche eine Öffnung aufweist, die von einer Folie verschlossen ist.The invention relates to a detection unit for detecting the withdrawal of medicaments from a packaging unit having at least one pocket for a medicament, wherein the bag has an opening which is closed by a film.
Die Erfindung sieht bei dieser Detektionseinheit vor, dass
- a) die Detektionseinheit eine erste Trägerschicht mit einer Anlagefläche zur Anlage an die Folie der Verpackungseinheit aufweist, wobei an der ersten Trägerschicht eine erste flache Elektrode angeordnet ist,
- b) parallel zur ersten Trägerschicht und/oder zur ersten Elektrode eine zweite an der ersten Trägerschicht anliegende Trägerschicht angeordnet ist, wobei an der zweiten Trägerschicht eine zweite flache Elektrode angeordnet ist, wobei die erste Elektrode und die zweite Elektrode einander gegenüberliegen, insbesondere überlappen,
- c) in der ersten Trägerschicht eine erste Perforation vorgesehen ist, die die erste Elektrode teilweise umgibt und in der zweiten Trägerschicht eine zweite Perforation vorgesehen ist, die die zweite Elektrode teilweise umgibt, und
- d) die erste und zweite Perforation derart angeordnet sind, dass Bereiche auf den beiden Trägern auf denen sich die Elektroden befinden, beim Hindurchpressen eines Arzneimittels von unterschiedlichen, insbesondere gegenüberliegenden, Anlenkbereichen und/oder nach unterschiedlichen Raumrichtungen wegklappen und sich die Elektroden derart voneinander entfernen.
- a) the detection unit has a first carrier layer with a contact surface for engagement with the foil of the packaging unit, wherein a first flat electrode is arranged on the first carrier layer,
- b) parallel to the first carrier layer and / or to the first electrode, a second carrier layer on the first carrier layer is disposed, wherein on the second carrier layer, a second flat electrode is disposed, wherein the first electrode and the second electrode opposite each other, in particular overlap,
- c) in the first carrier layer, a first perforation is provided which partially surrounds the first electrode and in the second carrier layer, a second perforation is provided, which partially surrounds the second electrode, and
- d) the first and second perforations are arranged in such a way that regions on the two carriers on which the electrodes are located fold away as the medicament presses from different, in particular opposite, articulation regions and / or according to different spatial directions and the electrodes thus move away from one another.
Wesentlicher Vorteil der Erfindung ist, dass die Detektion der Entnahme von Arzneimitteln aus der Tasche ohne zusätzliche Maßnahmen durch den Patienten möglich ist und die Detektionseinheit gleichzeitig sehr einfach aufgebaut ist und die Entnahme sowie die Einnahme des Arzneimittels wenig beeinträchtigt. Darüber hinaus ist die Detektion der Entnahme eines Arzneimittels zuverlässig durchführbar.An essential advantage of the invention is that the detection of the withdrawal of drugs from the bag is possible without additional measures by the patient and the detection unit is at the same time very simple and the removal and ingestion of the drug little affected. In addition, the detection of the removal of a drug is reliably feasible.
Eine besonders einfache Weiterbildung, bei der die Entnahme mittels Leitfähigkeitsmessung erreicht werden kann, sieht vor, dass die erste Elektrode und die zweite Elektrode zwischen den beiden Trägerschichten angeordnet sind, wobei die beiden Elektroden aneinander anliegen und derart einen leitenden Kontakt bilden.
Eine Ausführungsform, die eine kapazitive Detektion der Entnahme des Arzneimittels ermöglicht, sieht vor, dass dass die erste Elektrode und die zweite Elektrode zwischen den beiden Trägerschichten angeordnet sind, wobei
die beiden Elektroden durch eine isolierende Zwischenschicht getrennt sind und derart einen Kondensator ausbilden.
Zur kapazitiven Erfassung kann alternativ ebenfalls vorgesehen sein, dass die erste Elektrode an der Anlagefläche der ersten Trägerschicht angeordnet ist und die zweite Elektrode an der der ersten Trägerschicht zugewandten Seite der zweiten Trägerschicht angeordnet ist, wobei gegebenenfalls auf der ersten Elektrode eine isolierende Zwischenschicht angeordnet ist.A particularly simple development, in which the removal can be achieved by means of conductivity measurement, provides that the first electrode and the second electrode are arranged between the two carrier layers, wherein the two electrodes abut each other and thus form a conductive contact.
An embodiment, which allows a capacitive detection of the removal of the drug, provides that the first electrode and the second electrode are arranged between the two carrier layers, wherein
the two electrodes are separated by an insulating intermediate layer and thus form a capacitor.
For capacitive detection, it may alternatively also be provided that the first electrode is arranged on the contact surface of the first carrier layer and the second electrode is arranged on the side of the second carrier layer facing the first carrier layer is arranged, optionally on the first electrode, an insulating intermediate layer is arranged.
Hierbei ist es gerade bei metallischen Folien, die die Taschen verschließen, vorteilhaft, dass auf der ersten Elektrode eine isolierende Zwischenschicht angeordnet ist. Dies vermeidet wirksam Kurzschlüsse zwischen den Elektroden.In the case of metallic foils which close the pockets, it is advantageous in this case for an insulating intermediate layer to be arranged on the first electrode. This effectively avoids short circuits between the electrodes.
Eine weitere Detektionseinheit, die die Entnahme von Arzneimitteln kapazitiv detektiert, sieht vor, dass die erste Elektrode an der der Anlagefläche abgewandten Seite der ersten Trägerschicht angeordnet ist und die zweite Elektrode an der der ersten Trägerschicht abgewandten Seite der zweiten Trägerschicht angeordnet ist.A further detection unit, which detects the removal of medicaments capacitively, provides that the first electrode is arranged on the side of the first carrier layer facing away from the contact surface and the second electrode is arranged on the side of the second carrier layer facing away from the first carrier layer.
Eine mechanisch stabile Anordnung kann erzielt werden, indem eine an der zweiten Trägerschicht anliegende dritte Trägerschicht zur Versteifung der Detektionseinheit vorgesehen ist, und dass in der dritten Trägerschicht eine Ausnehmung vorgesehen, durch die die Tablette hindurchtreten kann und die die Elektroden tragende Bereiche der Trägerschichten freihält.
Eine besonders einfache Entnahme der Tabletten sowie eine zuverlässige Detektion der Entnahme kann gewährleistet werden, indem die Perforationen in den Trägerschichten teilweise deckungsgleich aneinander liegen.
Zum selben Zweck kann vorgesehen sein, dass die auf den Trägerschichten befindlichen Elektroden deckungsgleich aneinander anliegen oder einander gegenüberliegen.A mechanically stable arrangement can be achieved by providing a third carrier layer adjacent to the second carrier layer for stiffening the detection unit, and providing in the third carrier layer a recess through which the tablet can pass and keep the areas of the carrier layers carrying the electrodes free.
A particularly simple removal of the tablets and a reliable detection of the removal can be ensured by the perforations in the carrier layers are partially congruent to each other.
For the same purpose it can be provided that the electrodes located on the carrier layers congruently abut each other or face each other.
Eine besonders bevorzugte Variante zur elektrischen Kontaktierung der Elektroden sowie zur Ausbildung der Perforation zur Ermöglichung eines vorteilhaften Wegklappens der die Elektroden tragenden Trägerteile bei der Entnahme sieht vor, dass die auf der ersten und/oder der zweiten Trägerschicht jeweils angeordnete Perforation die jeweilige Elektrode teilweise umgibt, und
auf beiden Trägeschichten jeweils ein nicht perforierter Steg vorgesehen ist, mit dem der jeweilige die Elektrode tragende Bereich der Trägerschicht mit dem übrigen Bereich der Trägerschicht verbunden ist.
Ein Wegklappen der Elektroden, das eine rasche und dauerhafte kapazitive Änderung bewirkt, kann erzielt werden, indem die beiden Stege einander im Umfangsbereich der Elektroden gegenüberliegen.
Eine vorteilhafte Kontaktierung der Elektroden sieht vor, dass die jeweilige Elektrode mit einer auf der Trägerschicht über den Steg verlaufenden Leitung elektrisch leitend verbunden ist.A particularly preferred variant for making electrical contact with the electrodes and for forming the perforation to enable an advantageous folding away of the carrier parts carrying the electrodes during removal provides that the perforation respectively arranged on the first and / or the second carrier layer partially surrounds the respective electrode, and
on both Trägeschichten each a non-perforated web is provided, with which the respective electrode carrying the region of the carrier layer is connected to the remaining region of the carrier layer.
A folding away of the electrodes, which causes a rapid and permanent capacitive change, can be achieved by the two webs opposite each other in the peripheral region of the electrodes.
An advantageous contacting of the electrodes provides that the respective electrode is electrically conductively connected to a line extending over the web on the carrier layer.
Eine vorteilhafte Detektion der Entnahme sieht vor, dass die Elektroden jeweils, insbesondere über die Leitung, mit einem Messgerät elektrisch leitend verbunden sind, wobei das Messgerät die jeweilige Kapazität oder den Leitwert zwischen den beiden Elektroden ermittelt.An advantageous detection of the removal provides that the electrodes are each electrically conductively connected, in particular via the line, to a measuring device, the measuring device determining the respective capacitance or the conductance between the two electrodes.
Weiters betrifft die Erfindung eine Detektionsanordnung umfassend eine Vielzahl von erfindungsgemäßen Detektionseinheiten, wobei die Detektionseinheiten jeweils über eine gemeinsame erste und zweite Trägerschicht und eine gemeinsame Anlagefläche verfügen.Furthermore, the invention relates to a detection arrangement comprising a multiplicity of detection units according to the invention, wherein the detection units each have a common first and second carrier layer and a common contact surface.
Diese Detektionsanordnung ermöglicht eine besonders einfache Ausgestaltung einer Vielzahl von Detektionseinheiten in einem gemeinsamen Körper, insbesondere zur Detektion der Entnahme einer Vielzahl von Medikamenten aus den Taschen eines Arzneimittelblisters.This detection arrangement allows a particularly simple embodiment of a plurality of detection units in a common body, in particular for detecting the removal of a plurality of drugs from the pockets of a drug blister.
Vorteilhaft kann bei einer solchen Einheit vorgesehen sein, dass sämtliche ersten Elektroden miteinander leitend über eine erste gemeinsame Leitung verbunden sind und sämtliche zweiten Elektroden miteinander leitend über eine zweite gemeinsame Leitung verbunden sind und ein gemeinsames Messgerät vorgesehen ist, das die jeweilige Kapazität oder den Leitwert zwischen der ersten und der zweiten Leitung ermittelt.It can advantageously be provided in such a unit that all the first electrodes are connected to one another in a conductive manner via a first common line and all second electrodes are connected to one another in a conductive manner via a second common line and a common measuring device is provided, which switches the respective capacitance or the conductance between the first and the second line determined.
Dies ermöglicht eine einfache Detektion der Anzahl der entnommenen Arzneimittel, ohne dass hierfür eine aufwändige Multiplexschaltung erforderliche wäre.This allows a simple detection of the number of withdrawn drugs, without the need for a complex multiplex circuit would be required.
Eine besonders vorteilhafte Ausführungsform, die eine Ausbildung sämtlicher Trägerschichten auf einem gemeinsamen Träger ermöglicht, sieht vor, dass die erste und zweite Trägerschicht auf demselben gefalteten Träger angeordnet sind, wobei der Träger insbesondere zumindest drei durch Faltungsbereiche getrennte Teilbereiche aufweist, wobei der erste Teilbereich die erste Trägerschicht ausbildet, ein daran anschließender zweiter Teilbereich an der von der ersten Trägerschicht abgewandten Seite verläuft und Ausnehmungen zum Durchtritt von Taschen aufweist und ein an den zweiten Teilbereich anschließender dritter Teilbereich mit dem ersten Teilbereich flächig verbunden oder verbindbar ist und die zweite Trägerschicht ausbildet.
Weiters betrifft die Erfindung eine Verpackungseinheit die zumindest eine Tasche für ein Arzneimittel aufweist, wobei die Tasche eine Öffnung aufweist, die von einer Folie verschlossen ist, umfassend zumindest eine erfindungsgemäße Detektionseinheit, wobei die Anlagefläche der Detektionseinheit an der Folie anliegt und
- die erste und zweite Elektrode im Durchtrittsbereich der Öffnung angeordnet sind und/oder
- die erste und zweite Perforation den Durchtrittsbereich der Öffnung zumindest teilweise umgeben.
Furthermore, the invention relates to a packaging unit which has at least one pocket for a drug, wherein the pocket has an opening which is closed by a film, comprising at least one detection unit according to the invention, wherein the contact surface of the detection unit is applied to the film and
- the first and second electrodes are arranged in the passage region of the opening and / or
- the first and second perforations at least partially surround the passage area of the opening.
Schließlich betrifft die Erfindung eine Arzneimittelblisteranordnung umfassend
- einen Grundkörper, in dem eine Vielzahl von Taschen für Arzneimittel ausgebildet sind, wobei die Taschen jeweils eine Öffnung aufweisen, die von einer Folie verschlossen ist, sowie
- eine erfindungsgemäße Detektionsanordnung. Bei der Arzneimittelblisteranordnung ist vorgesehen, dass
- die Anlagefläche der Einheit an der Folie anliegt und je eine erste und
je eine zweite Elektrode jeweils im Bereich einer der Öffnungen angeordnet sind und/oder je eine erste und zweite Perforation den Durchtrittsbereich jeweils einer Öffnung zumindest teilweise umgeben.
- a base body in which a plurality of pockets for drugs are formed, wherein the pockets each have an opening which is closed by a foil, as well as
- a detection arrangement according to the invention. In the drug blister assembly is provided that
- the contact surface of the unit rests against the foil and a respective first and
each a second electrode are each arranged in the region of one of the openings and / or each a first and second perforation at least partially surround the passage region in each case an opening.
Die
The
In den
In.
Die in
In the
Weiters weist sowohl die erste als auch die zweite Trägerschicht 110, 120 jeweils eine Perforation 112, 122 auf. Wie in
Im vorliegenden Fall liegen die Perforationen 112, 122 in den Trägerschichten teilweise einander deckungsgleich gegenüber. Auch die Elektroden 111, 121 liegen deckungsgleich aneinander an bzw. einander gegenüber.In the present case, the
In
In
In
Grundsätzlich ist es nicht erforderlich, dass die beiden Trägerschichten 110, 120 die beiden Elektroden 111, 121 umgeben. Alternativ ist es auch möglich, dass die Elektroden 111, 121 einander an einer der beiden Trägerschichten 110, 120 gegenüberliegen. In
Bei einer weiteren, in
Bevorzugt kann bei allen dargestellten Ausführungsformen der Erfindung vorgesehen sein, dass die der Verpackungseinheit 200 zugewandte Anlagefläche 199 der Detektionseinheit 100 mit einer Klebeschicht beschichtet ist, mit der die Detektionseinheit 100 an der Verpackungseinheit 200 anheftet.In all the illustrated embodiments of the invention, it can preferably be provided that the
In
Für sämtliche Ausführungsbeispiele haben die Elektroden eine Schichtdicke von etwa 5 bis 100 µm. Die Trägerschichten 110, 120 haben eine Schichtdicke im Bereich von ca. 100 bis 500 µm. Die in
In den
Die in
Bei der in
Somit wird für jede Detektionseinheit 400a, 400b der Detektionsanordnung 400 jeweils ein Kondensator ausgebildet, mit dem die Entnahme des jeweiligen Arzneimittels 501a, 501b aus der jeweiligen Tasche 502a, 502b detektierbar ist.At the in
Thus, a respective capacitor is formed for each
Alternativ ist es auch möglich, eine für die gesamte Detektionsanordnung gemeinsame isolierende Zwischenschicht vorzusehen. Diese kann entweder perforiert ausgebildet zu sein, um einen Durchtritt der Arzneimittel 501a, 501b zu ermöglichen oder aber leicht durchzureißen sein.Alternatively, it is also possible to provide an insulating intermediate layer common to the entire detection arrangement. This may be either perforated to allow passage of the
In
In
Alternativ ist es auch möglich, eine für die gesamte Detektionsanordnung gemeinsame isolierende Zwischenschicht vorzusehen. Diese kann entweder perforiert ausgebildet zu sein, um einen Durchtritt der Arzneimittel 501a, 501b zu ermöglichen oder aber leicht durchzureißen sein.In
Alternatively, it is also possible to provide an insulating intermediate layer common to the entire detection arrangement. This may be either perforated to allow passage of the
In
In
In
Die jeweilige zweite Elektrode 421a, 421b ist jeweils mit einer Leitung 423a, 423b elektrisch leitend verbunden. Die Leitung ist zu einem Kontakt 481a, 481b geführt, die sich auf einem Kontaktbereich 480 der zweiten Trägerschicht 420 befindet.The respective
Bei sämtlichen dargestellten Ausführungsformen von Detektionseinheiten 100, 400a, 400b kann die Entnahme des Arzneimittels 201, 501a, 501b jeweils ermittelt werden, indem die Leitfähigkeit oder die Kapazität zwischen den beiden Elektroden 111, 121, 411a, 411b, 421a, 421b ermittelt wird. Sofern mehrere Elektroden 411a, 411b, 421a, 421b auf einem gemeinsamen Träger 410, 420 angeordnet sind, wird jeweils die Kapazität zwischen den einander gegenüber liegenden Elektroden 411a, 421a; 411b, 421b ermittelt. Es ist dabei möglich, dass für jedes Paar einander gegenüber liegender und einen Kondensator ausbildender Elektroden jeweils ein eigenes Messgerät zur Kapazitätsmessung vorgesehen ist, oder dass die einzelnen Anschlüsse über zwei Auswahlschaltungen, insbesondere Multiplexer, jeweils an die Anschlüsse des Messgeräts angeschlossen sind.In all illustrated embodiments of
In den
In
In
Eine Messung kann einerseits derart erfolgen, dass in vorgegebenen, insbesondere periodischen, Zeitabständen eine Kapazitätsmessung durchgeführt wird und für den Fall, dass sich die Kapazität um einen einen vorgegebenen Schwellenwert übersteigenden Wert ändert, eine Tablettenentnahme als detektiert gilt und ein vorab auf die Anzahl der Tabletten im Arzneimittelblister 500 eingestellter Wert jeweils um 1 reduziert wird. Alternativ kann auch vorgesehen sein, dass aufgrund des konkreten Werts der Kapazität zwischen den beiden Leitungen 413, 423 unmittelbar auf die Anzahl der Tabletten im Arzneimittelblister 500 geschlossen wird.On the one hand, a measurement can be carried out in such a way that a capacitance measurement is carried out at predetermined, in particular periodic time intervals and, in the event that the capacitance changes by a value exceeding a predetermined threshold value, a tablet removal is considered to be detected and an advance on the number of tablets The value set in
In
In
Claims (13)
- A detection unit (100) for detecting the removal of medicines (201) from a packaging unit (200) comprising at least one pocket (202) for a medicine (201), wherein the pocket (202) has an opening (203) which is closed by a foil (204),
whereina) the detection unit (100) has a first carrier layer (110) with a contact area (199) for contacting the foil (204) of the packaging unit (200), wherein a first flat electrode (111) is arranged on the first carrier layer (110),b) a second carrier layer (120) is arranged parallel to the first carrier layer (110) and/or the first electrode (111), contacting the first carrier layer (110), wherein a second flat electrode (121) is arranged on the second carrier layer (120), wherein the first electrode (111) and the second electrode (121) lie opposite one another, in particular overlap one another,c) a first perforation (112) is provided in the first carrier layer (110), which partially surrounds the first electrode (111), and a second perforation (122) is provided in the second carrier layer (120), which partially surrounds the second electrode (121), andd) the first and second perforations (112, 122) are arranged in such a way that, when a medicine (201) is pressed through, regions on the two carriers (110, 120) on which the electrodes (111, 121) are located swing away from different articulated regions, in particular lying opposite one another, and/or in different spatial directions, and the electrodes (111, 121) are in this way separated from one another. - The detection unit (100) according to claim 1, characterised in that the first electrode (111) and the second electrode (121) are arranged between the two carrier layers (110, 120), whereina) the two electrodes (111, 121) contact one another and in this way form a conductive contact, orb) the two electrodes (111, 121) are separated by an insulating intermediate layer (130) and in this way form a capacitor.
- The detection unit (100) according to claim 1, characterised in that the first electrode (111) is arranged on the contact area (199) of the first carrier layer (110) and the second electrode (121) is arranged on the side of the second carrier layer (120) facing the first carrier layer (110), wherein an insulating intermediate layer (140) is arranged opposite the first electrode (111) if necessary or in that the first electrode (111) is arranged on the side of the first carrier layer (110) facing away from the contact surface (199) and the second electrode (121) is arranged on the side of the second carrier layer (120) facing away from the first carrier layer (110).
- The detection unit (100) according to claim 1, characterised in that a third carrier layer (150) contacting the second carrier layer (120) is provided in order to stiffen the detection unit (100), and in that a recess (151) is provided in the third carrier layer (150), through which the tablet can pass and which keeps free the regions of the carrier layers (110, 120) carrying the electrodes (111, 121).
- The detection unit (100) according to any one of the preceding claims, characterised in thata) the perforations (112, 122) in the carrier layers (110, 120) are partially congruent to each other and/orb) the electrodes (111, 121) located on the carrier layers are congruent to each other or face each other.
- The detection unit (100) according to any one of the preceding claims, characterised in that the perforations (112, 122) arranged respectively on the first and/or second carrier layer (110, 120) partially surround the respective electrodes (111, 121), and
a non-perforated web (114, 124) is provided on each of the two carrier layers (110, 120), with which the region of the carrier layer (110, 120) carrying the respective electrode (111, 121) is connected to the remaining region of the carrier layer (110, 120). - The detection unit (100) according to claim 6, characterised in that- the two webs (114, 124) lie opposite one another in the peripheral region of the electrodes (111, 121) and/or- in that the respective electrode (111, 121) is connected in an electrically conductive manner to a lead (113, 123) extending over the web (114, 124) on the carrier layer (110, 120).
- The detection unit (100) according to any one of the preceding claims, characterised in that the electrodes (111, 121) are each connected in an electrically conducting manner to a measurement device, in particular via the lead (113, 123), wherein the measurement device determines the respective capacitance or conductance between the two electrodes (111, 121).
- A detection arrangement (400) comprising a plurality of detection units (400a, 400b) according to any one of the preceding claims, wherein the detection units each have a common first and second carrier layer (410, 420) and a common contact area (499).
- The detection arrangement (400) according to claim 9, characterised in that all the first electrodes (411a, 411b) are conductively connected together via a first common lead (413) and all the second electrodes (421a, 421b) are conductively connected together via a second common lead (423) and a common measuring device is provided which determines the respective capacitance or conductance between the first and second lead (413, 423).
- The detection arrangement (400) according to claim 9 or 10, characterised in that the first and second carrier layer (410, 420) are arranged on the same folded carrier,
wherein the carrier comprises, in particular, at least three subregions separated by folding regions (490), wherein the first subregion forms the first carrier layer (410), a second adjoining subregion (460) extends on the side facing away from the first carrier layer (410) and comprises recesses (461a, 461b) for the passage of pockets (502) and a third subregion adjoining the second subregion is connected or connectable to the first subregion in a planar manner and forms the second carrier layer (420). - A packaging unit (300) which comprises at least one pocket (202) for a medicine (201), wherein the pocket (202) comprises an opening (203) which is closed by a foil (204), comprising at least one detection unit (100) according to any one of claims 1 to 9, wherein the contact area (199) of the detection unit (100) contacts the foil (204) and- the first and second electrode (111, 121) are arranged in the passage region of the opening (203) and/or- the first and second perforation (112, 122) at least partially surround the passage region of the opening (203).
- A medicine blister arrangement (600) comprising- a base body (505) in which a plurality of pockets (502a, 502b) for medicines (501a, 501b) are formed, wherein the pockets (502a, 502b) each comprise an opening (503a, 503b) that is closed by a foil (204), and- a detection arrangement according to anyone of claims 9 to 11, characterised in that- the contact area (499) of the unit contacts the foil (404) and a first and
a second electrode (411a, 411b, 421a, 421b) are each arranged in the region of one of the openings (503a, 503b) and/or a first and second perforation (412a, 412b, 422a, 422b) at least partially surrounds the passage region of each opening (503a, 503b).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ATA50478/2014A AT515940B1 (en) | 2014-07-09 | 2014-07-09 | Detection unit for detecting the withdrawal of drugs |
PCT/AT2015/050147 WO2016004451A1 (en) | 2014-07-09 | 2015-06-10 | Detection unit for detecting the removal of medicines |
Publications (2)
Publication Number | Publication Date |
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EP3166565A1 EP3166565A1 (en) | 2017-05-17 |
EP3166565B1 true EP3166565B1 (en) | 2018-04-25 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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EP15741715.5A Not-in-force EP3166565B1 (en) | 2014-07-09 | 2015-06-10 | Detection unit for detecting the removal of medicines |
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EP (1) | EP3166565B1 (en) |
AT (1) | AT515940B1 (en) |
WO (1) | WO2016004451A1 (en) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
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SE463348B (en) * | 1988-03-29 | 1990-11-12 | Compumed Ab | DEVICE FOR SIGNAL OF ADMINISTRATION OF MEDICINAL TABLETS |
EP2113235A1 (en) * | 2008-04-28 | 2009-11-04 | Alcan Technology & Management AG | Lid and seal foil for an item of packaging and method for determining the opening state of an item of packaging |
ITRM20110072A1 (en) * | 2011-02-16 | 2012-08-17 | Osvaldo Tufi | "DOOR BLISTER ACT TO INDICATE TO A USER THE NUMBER OF PRODUCTS EXTRACTED BY THE BLISTER AND TO DIALOGUATE IN REMOTE WITH AN ENABLED CONTROL CENTER" |
CA2775546A1 (en) * | 2012-04-25 | 2013-10-25 | Intelligent Devices Inc. | A disposable content use monitoring package with indicator and method of making same |
-
2014
- 2014-07-09 AT ATA50478/2014A patent/AT515940B1/en not_active IP Right Cessation
-
2015
- 2015-06-10 EP EP15741715.5A patent/EP3166565B1/en not_active Not-in-force
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AT515940A4 (en) | 2016-01-15 |
EP3166565A1 (en) | 2017-05-17 |
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AT515940B1 (en) | 2016-01-15 |
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