Classifications

• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
  • A01N59/12—Iodine, e.g. iodophors; Compounds thereof
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
  • A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
  • A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
  • A01N31/16—Oxygen or sulfur directly attached to an aromatic ring system with two or more oxygen or sulfur atoms directly attached to the same aromatic ring system
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
  • A01N33/02—Amines; Quaternary ammonium compounds
  • A01N33/12—Quaternary ammonium compounds
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
  • A01N35/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aliphatically bound aldehyde or keto groups, or thio analogues thereof; Derivatives thereof, e.g. acetals
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
  • A01N37/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group; Thio analogues thereof
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
  • A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
  • A01N37/38—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
  • A01N37/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system having at least one carboxylic group or a thio analogue, or a derivative thereof, and one oxygen or sulfur atom attached to the same aromatic ring system
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
  • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
  • A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
  • A01N47/44—Guanidine; Derivatives thereof
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
  • A01N59/14—Boron; Compounds thereof

Definitions

• the invention relates to a formulation which contains a suspension solution of substances or their compounds in water, alcohols and other volatile solvents or their mixtures, with the content of acrylate copolymer and/or nitrocellulose for incapacitating, dehydrating, rapid killing and disinfection of a blood-sucking and firmly stuck parasite, i.e. in particular a tick or a leech, and its easy and safe removal from the place of sticking of a host.
• the said formulation can be used for efficient disinfecting of the given parasite itself.
• Formulations or methods used for removing a blood-sucking and firmly stuck parasite, in particular a tick or a leech are usually amateur ones (e.g. by shaking out, tearing off etc.), or lengthy and with locally limited usability (e.g. a plaster with a disinfection formulation which is hard-to-be-applied in body folders, hair etc., which are commonly the most frequently occurring places of sticking for a tick).
• This "amateur" method may result in residues of the removed parasite remaining in the place of sticking, which may consequently result in the importation of infection into the host's body.
• One of the other known methods for removing a stuck tick is its removal by means of a special card with slots without prior application of any formulations on the place of sticking.
• the attached special card firmly catches hold of the tick and pulls it out without squeezing the tick and pushing out the content of its intestines into the wound.
• user instructions 2 being attached to the card, it is problematic whether the removing person is skilful enough to remove it without problems, in particular at parts of the body which are difficult to reach.
• Another common method is applying an oil or any fat on the place with the tick, when the greased tick is stifled and consequently removed. There is a high risk in this method that the content of tick's intestines can be thrown out directly to the host's wound before its death.
• Another solution for removing a tick is using alcohol, water- alcohol and other solutions of iodine and/or its compounds with the addition of suitable substances which are able to polymerize.
• a disinfection solution modified in this way a many times higher quantity of an active disinfection substance is applied on the tick as well as on the affected place, and at the same time the formed film of polymerizing substances significantly slows down the evaporation of the solvent and prolongs the contact time of the disinfection substance (still present in the liquid state) with the tick and the skin, which results in prolonging the disinfecting effect.
• the advantage of this method is an easier application on any place of the skin.
• a disadvantage of this application is the fact that after evaporation of volatile substances and completed polymerization, the lodged tick and the surrounding area, where the formulation was applied, remain covered with a dried residue of the formulation which is firmly stuck on the skin and causes problems when removed from the skin.
• the subject-matter of the invention is a formulation containing a suspension solution of substances with disinfecting effect or their compounds in water, alcohols and other volatile solvents or mixtures thereof, with the content of acrylate copolymer and/or nitrocellulose for incapacitating, dehydrating, rapid killing and disinfection of a blood-sucking firmly stuck parasite and its easy removal from the place of sticking of the host, which contains up to 25 % by weight of the powder form of a solid inert substance and/or a mixture of solid inert substances based on the weight of all ingredients of the suspension solution, with the specific area of at least 1 m 2 /g.
• a firmly stuck parasite is preferably a tick or a leech.
• the formulation is a solution of substances with disinfecting effect and moreover, the composition of this formulation contains a powder form of solid inert substances (fillers) and/or mixtures of these solid inert substances, which can be contained up to 25 % by weight based on the weight of all the ingredients of the suspension solution, where their specific area is at least 1 m 2 /g.
• fillers solid inert substances
• mixtures of these solid inert substances which can be contained up to 25 % by weight based on the weight of all the ingredients of the suspension solution, where their specific area is at least 1 m 2 /g.
• the formulation according to the present invention has also strong dehydrating effects which results in all the liquids contained in the tick being absorbed in the applied formulation, which is another cause avoiding the entry of tick's body liquids into the wound.
• the killed, dehydrated and disinfected tick or leech can be easily removed using a pair of tweezers or other suitable manner.
• the suitable design of this invention is the formulation which contains up to 25 w% of the powder form of a solid inert substance, related to the weight of all the ingredients of the suspension solution and or the mixture of solid inert substances with a high specific area (i.e. a low weight in volume), of at least 100 m 2 /g.
• Suitable inert substances according to this invention are powder forms of inert substances, i.e. fine powders of inorganic oxides such as SiCVaerosil, ⁇ 1 2 ⁇ 3, or inorganic pigments such as Ti0 2 , or Si0 2 obtained in the chemical way (usually by pyrohydrolysis from volatile chlorides), a fine ground or precipitated calcium carbonate, magnesium carbonate, calcium- magnesium carbonate - dolomite, dialumino silicates, magnesium dialumosilicates such as magnesium aluminate metasilicate, chalk, talk, calcium phosphate, calcium silicate, bergmeal, mineral powder, quartz powder, porcelain clay, apatite, bentonite, perlite, vermiculite or their mixtures.
• Particularly suitable inert substances are Si0 2 -aerosil, bentonite or powdered Ti0 2 .
• suitable disinfection substances are, in the reasonable quantity, iodine and its compounds (i.e. with potassium iodide or sodium iodide, iodine- povidon, iodine-phenol), and
• aldehydes (formaldehyde, glutaraldehyde, ortho-phthalaldehyde),
• quaternary ammonium salts (benzododecinium salts, carbetopendecinium salts, cetrimide), chlorhexidine digluconate,
• boric acid salicylic acid, peroxo-acetic acid, peroxo-formic acid, potassium hydrogen peroxo sulphate,
• ethanol can be used as a solvent
• diethyl ether contained according to the background art according to the CZ 20342 Ul utility model can be partly or fully replaced with similar, less volatile substances, e.g. propanol or isopropanol and methyl tertiary butyl ether.
• the used solution of nitrocellulose in diethyl ether can be replaced according to this technical solution with a suspension water-alcohol gel with similar effect on incapacitating, dehydrating, disinfection and killing a tick.
• Example 9 A suspension solution containing 37.5 w% of diethyl ether, 36.5 w% of ethanol, 5 w% of nitrocellulose and 1 w% of phenol, containing 20 w% of chemically precipitated CaC0 3
• the tick or the leech were very quickly incapacitated, dehydrated and consequently killed in all of these cases, the tick or the leech as well as the wound were disinfected and the residue of the formulation was easily crumbled away and the tick or the leech easily removed.
• the formulation is intended for the rapid incapacitation, killing and dehydration of a tick and concurrent efficient disinfection of the tick itself.

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• Life Sciences & Earth Sciences (AREA)
• General Health & Medical Sciences (AREA)
• Agronomy & Crop Science (AREA)
• Plant Pathology (AREA)
• Health & Medical Sciences (AREA)
• Engineering & Computer Science (AREA)
• Dentistry (AREA)
• Wood Science & Technology (AREA)
• Zoology (AREA)
• Environmental Sciences (AREA)
• Pest Control & Pesticides (AREA)
• Inorganic Chemistry (AREA)
• Chemical & Material Sciences (AREA)
• Agricultural Chemicals And Associated Chemicals (AREA)

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• 2014
  • 2014-04-09 CZ CZ2014-240A patent/CZ306491B6/cs unknown
• 2015
  • 2015-04-09 WO PCT/CZ2015/000033 patent/WO2015154731A1/en active Application Filing
  • 2015-04-09 EP EP15720897.6A patent/EP3128837A1/de not_active Withdrawn

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