Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
  • A61K8/04—Dispersions; Emulsions
  • A61K8/06—Emulsions
  • A61K8/062—Oil-in-water emulsions
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
  • A61K8/04—Dispersions; Emulsions
  • A61K8/046—Aerosols; Foams
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K9/00—Medicinal preparations characterised by special physical form
  • A61K9/0012—Galenical forms characterised by the site of application
  • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
  • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q19/00—Preparations for care of the skin
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
  • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
  • B65D83/00—Containers or packages with special means for dispensing contents
  • B65D83/14—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
  • B65D83/60—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant with contents and propellant separated
  • B65D83/64—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant with contents and propellant separated by pistons
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
  • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
  • A61K2800/87—Application Devices; Containers; Packaging
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
  • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
  • A61K2800/88—Two- or multipart kits
  • A61K2800/882—Mixing prior to application

Definitions

• Aerosol container comprising a dermatological composition and a foaming agent.
• the present invention relates to aerosol containers comprising a dermatological composition and a foaming agent.
• the present invention relates to aerosol containers comprising a dermatological composition, which comprises an oil-in-water emulsion, one or more oil-in- water emulsifiers and one or more active ingredients. More in particular still, the invention relates to leave on compositions and hence different from rinse off composition comprising significant amounts of soap.
• Dermatological compositions can be divided into compositions that are to be removed from the skin after application and compositions that are intended to be left on the skin, i.e. so- called stay-on or leave-on dermatological compositions.
• compositions in the form of a foam, e.g. a foaming sunscreen composition.
• Foaming leave-on dermatological compositions delivered by state of the art aerosol containers come in many different forms and textures.
• the quality of such foams leaves something to be desired, i.e. the delivered foams tend to be too dry, coarsely-bubbled and/or only slightly stable, leading to the composition simply dripping or flowing from the skin after application.
• a suitable foam should be easy to spread, have a certain density associated with it and stand for at least the time a person needs to spread the foam over the skin. Further, a suitable foam should adhere to the skin without being too sticky.
• a foam that fulfils these criteria is, in the context of the present application, denoted a rich foam.
• EP1508326 seeks to provide a solution for the above disadvantages of current foaming cosmetic and dermatological compositions. It is related to the use of UV filter substances for optimizing the quality of self-foaming, foam-like, after-foaming or foamable cosmetic and dermatological preparations.
• the described compositions can be emulsions. Said preparations are preferably removed from two-chamber aerosol containers, in which there is one chamber with a filling of the liquid or slurry-like preparations that may comprise a secondary propellant, under the pressure of a primary propellant located in a second chamber, enclosing the first chamber.
• Bican ® aerosol containers in which the product is enclosed in a flexible bag are mentioned as an example.
• EP1508326 in certain cases indeed delivers a rich foam, there are some disadvantages associated with the provided solution. As it turns out, it is not always convenient or needed to have one or more of the particular UV-filters present in
• dermatological compositions In addition, in practice it turns out that not every dermatological composition comprising one or more UV-filters and a secondary propellant leads to a suitable foam, i.e. a foam that is rich enough as not to drip from the skin and that allows for easy spreading.
• a dermatological composition is disclosed, albeit that it is very viscous in nature and that it contains a soap based on a fatty acid and hence has a rinse-off composition as its subject-matter, rather than a leave-on composition.
• a secondary propellant may be contained in a flexible bag that is surrounded by an aerosol container that is pressurized with a primary propellant.
• an emulsifier system must be employed that consists of three different emulsifiers. It is evident that the use of three different emulsifiers makes the composition complex and potentially unsuitable for several uses.
• the valve-on bag system is not ideal. In particular for leave-on compositions, better solutions would be desirable.
• an aerosol container defining at least a first chamber, wherein a pressurized gas is contained, and at least a second chamber that is separated from the first chamber by a movable, gas-tight, solid wall, and wherein a closable outlet is in fluid communication with said second chamber, said second chamber comprising a leave-on dermatological composition comprising: - an oil-in-water emulsion, comprising one or more oils, the emulsion having an oil phase to water phase ratio of between 1 : 1 and 1 :25;
• said leave-on dermatological composition has a viscosity at room temperature of between 1 and 20,000 mPa.s and wherein said second chamber further comprises one or more physical foaming agents having a standard boiling point of -50 to 70 °C.
• compositions provide a satisfactory foaming behaviour, whereas compositions with a different viscosity fail to provide such foaming performance.
• the one or more physical foaming agents have a standard boiling point of - 50 to 40 °C, and are suitably selected from propane, butane, isobutane, pentane,
• the leave-on dermatological compositions contained in the aerosol containers preferably have a viscosity at room temperature of between 50 and 20,000 mPa.s, more preferable between 100 and 15,000 mPa.s.
• the leave-on dermatological composition contained in the aerosol containers is a skin care formulation, examples of which are a body lotion, a sunscreen formulation, an after sun formulation, a tanning lotion and a baby care composition such as a nappy rash cream.
• the invention also provides a method for filling the aerosol container, comprising the steps of:
• the dermatological composition to be filled into the container via this method is suitably a leave-on dermatological composition that has a viscosity at room temperature of between 1 and 20,000 mPa.s, and is advantageously a leave-on-dermatological composition as described above.
• This method surprisingly has the advantage that the filling speed can be increased significantly, in particular in comparison with the embodiment wherein the foaming agents and the emulsion are combined prior to being added to the second chamber. It would be disadvantageous to fill the second chamber with emulsion before adding the foaming agent, since, the liquid foaming agent would potentially not mix sufficiently with the emulsion and be sprayed from the aerosol prior to the spraying of the emulsion, thereby negatively affecting the foaming of the composition.
• a particular advantage of employing the filling method according to the invention for dermatological compositions as described above, with a viscosity of 1 to 20,000 mPa.s resides in that such compositions readily and spontaneously mix with the physical foaming agents that have been introduced into the second chamber previously. The spontaneous mixing benefits the foaming behaviour when the composition is released from the aerosol container.
• the present invention provides a aerosol container having at least two chambers that are separated from each other by a movable, gas-tight, solid wall, comprising a leave-on dermatological composition as defined having a viscosity between 1 and 20,000 mPa.s and one or more physical foaming agents having a standard boiling point of between -50 to 70 °C. Note that this is different from a bag-on-valve system, where the composition is enclosed in a bag and hence not separated by a solid wall.
• the inventors found that the combination of one or more physical foaming agents and a leave-on dermatological composition having the desired viscosity leads to a rich foam upon discharging the aerosol container.
• a dermatological composition and one or more physical foaming agents will be referred to as a "formulation”.
• Leave-on dermatological compositions that are applied as a foam have a clear advantage over their unfoamed counterparts. Most people are familiar with the experience of spilling a substantial part of sunscreen lotion because it runs too easily from the skin. When a typical leave-on dermatological composition such as a body lotion or a sunscreen lotion, is applied to the skin, it is difficult to spread the composition evenly and uniformly over those parts of the skin that one intents to rub in. Usually, the spot where the composition is applied, is overloaded, leading to an oily or greasy feeling on that spot, whereas the adjacent parts of the skin are poorly covered, this effect increasing when moving further away from the application spot. Also well-known is the problem that when spreading a clot of a certain skin care composition, it may well be that some spots are left uncovered. In the case of sunscreen lotion, this may result in sun burning of these spots.
• dermatological compositions are applied as a foam.
• the dermatological compositions have a viscosity at room temperature of between 1 and 20,000 mPa.s. Though it might be possible to foam a dermatological composition having a viscosity below 1 mPa.s, it is currently impossible to prepare oil-in-water emulsions that have a viscosity below 1 mPa.s. When the viscosity is higher than 20,000 mPa.s, no stable leave-on foam develops upon discharging the dermatological composition.
• the viscosity at room temperature preferably is between 50 and 20,000 mPa.s, more preferably between 100 and 15,000 mPa.s. From US 6620855 it is apparent that in the relevant art the viscosity is a known parameter which the skilled person will know how to determine. For the purpose of this application the viscosity is the one obtained by a Brookfield RV viscometer, wherein the viscosity is measured at room temperature (20°C) at the appropriate rotation speed using the appropriate spindle after 1 minute.
• the afore-mentioned one or more physical foaming agents should have a standard boiling point of between -50 to 70 °C, whereby 'standard' indicates the boiling point under standard atmospheric conditions.
• the physical foaming agents have a standard boiling point of between -45 to 40 °C, more preferably between -45 to 30 °C.
• Examples of physical foaming agents include linear, branched or cyclic alkanes having 3-6 carbon atoms, carbon dioxide, dimethyl ether, hydrofluorocarbons, hydrochlorofluorocarbons,
• hydrofluoroethers methyl formate and mixtures thereof. Their derivatives may also be used.
• the one or more physical foaming agents are selected from propane, butane, isobutane, pentane, isopentane, dimethyl ether and mixtures thereof.
• the aerosol container of the present invention is an aerosol container, with at least two chambers, in which the product is contained in the second chamber that is attached to the outlet valve and wherein the propellant is contained separate from the formulation in the first chamber.
• aerosol containers are known in the art, and may be in the form of delaminating bottles, tube in tube, piston in can, and combinations thereof.
• the first chamber advantageously is provided with a pressure regulator to reduce the pressure variation on the solid wall that separates the first chamber from the second chamber.
• a pressure regulator is described in US 6499632 and US 7748578. Such a pressure regulator is positioned in the container in a gas- tight manner and comprises a closing member that provides an interruptible communication between the first chamber and a space underneath the solid wall.
• the closing member opens and gas is released from the first chamber into the space between the solid wall and the pressure regulator.
• the pressure regulator may be provided on a separate housing representing the first chamber, that is connected to a second housing, representing the first chamber, the two housings together forming the aerosol container. In many respects this resembles a third chamber.
• AiropackTM container This container consists of a blow- molded plastic container fitted with a compressed air chamber and the pressure control device to protect against pressure drop, improve ease of use and ensure the maximum amount of product can be extracted from the container. Since it is made entirely of plastic it can be recycled after use.
• a suitable plastic is polyethylene terephthalate (PET).
• pressurized gas is not critical, i.e. any suitable gas may be employed.
• suitable gases include alkanes having 3-6 carbon atoms, cyclobutane, cyclopentane, oxygen, dimethyl ether, helium, air and nitrogen.
• the pressurized gas is a readily available and environmentally friendly gas such as air or nitrogen.
• a closable outlet is in fluid communication with the second chamber.
• this outlet comprises a valve and an actuator.
• the actuator When the actuator is activated, e.g. pressed, the product comprised in the second chamber is discharged through the valve assembly by the driving force the pressurized gas exerts on the movable gas-tight solid wall.
• the second chamber comprises a leave-on dermatological composition that can be foamed.
• a dermatological composition is a composition that has a caring, cleansing or decorative effect on the skin. Dermatological compositions can be subdivided in cosmetic and medicinal dermatological compositions. Examples of dermatological compositions include baby care compositions, body lotions, sunscreen lotions, cleansing milks and related compositions.
• the leave-on dermatological compositions of the invention comprise an oil-in-water emulsion, one or more oil-in-water emulsifiers and one or more active dermatological ingredients.
• a dermatological composition influences the choice of ingredients for that dermatological composition.
• the nature and the amounts of oils and emulsifiers present in a dermatological composition determines the basic characteristics of the dermatological composition, such as spreading, appearance, skin absorption, skin feel, etc.
• the addition of dermatological active ingredients and/or vitamins promotes specific categories of skin care such as extra nourishing, hydrating, tanning acceleration, masking, etc.
• the present invention comprises an oil-in-water emulsion.
• a water-in-oil emulsion when employed in an aerosol container of the present invention, provides a watery, unstable foam. Therefore the present invention utilizes oil-in-water emulsions.
• the leave-on dermatological composition utilizes one or more oils instead of an oil-water-emulsion.
• the leave-on dermatological composition is water-free and the presence of one or more oil-in-water emulsifiers is not required.
• the one or more oils are lipids as defined below.
• the oil phase to water phase ratio of the oil-in-water emulsion should be between 1 : 1 and 1 :25.
• the oil phase typically comprises oils, waxes, oil-soluble emulsifiers and other oil- soluble ingredients.
• the water phase typically comprises water and other water-soluble ingredients.
• oil or oils contained in the oil-in-water emulsion is not particularly limited. In fact, every oil or combination of oils commonly used in dermatological
• the oil may be a mineral oil, a lipid, a silicone based oil, or a mixture comprising these oils.
• lipids include vegetable oils, esters such as triglycerides, ethers such as dicaprylyl ether, fatty acids or phospholipids.
• the oil is a lipid or a silicone based oil.
• Suitable lipids include, but are not limited to, C12-C15 alkyl benzoates, capric and caprylic triglycerides, diethylhexyl adipate, dibutyl adipate, diisopropyl adipate, diethylhexyl malate, ethylhexyl palmitate, ethylhexyl stearate, isopropyl myristate, isopropyl palmitate, octyldodecyl neopentanoate, PPG-2 myristyl ether propionate, butylene glycol dicaprylate/dicaprate, dicaprylyl ether, triheptanoin, dicaprylyl carbonate and diisopropyl sebacate.
• Suitable silicone based oils include cyclopentasiloxane and cyclohexasiloxane, dimethicone and phenyltrimethicone.
• the oil is selected from C12-C15 alkyl benzoates, ethylhexyl cocoate, dicaprylyl carbonate, dibutyl adipate, cyclopentasiloxane, dimethicone and mixtures thereof.
• the nature of the one or more emulsifiers is not particularly limited. In fact, every emulsifier or combination of emulsifiers commonly used in dermatological compositions can be used.
• the one or more emulsifiers are selected from salt and esters of fatty acids having 10 to 40 carbon atoms, alkyl phosphates having 12 to 20 carbon atoms and their salts, polyglycerol esters, glucosides, sucrose esters and polyethylene glycol esters (PEG) esters.
• the emulsifiers are one or more selected from sorbitan stearate, glyceryl stearate, PEG-100 stearate, potassium cetyl phosphate, polysorbate 80, bis- PEG/PPG-16/16 PEG/PPG-16/16 dimethicone, acrylates/vinyl isodecanoate crosspolymer, ceteareth-20, acrylates/C10-30 alkyl acrylates cross-polymer and laureth-7.
• a leave-on composition differs from a rinse-off composition.
• a rinse-off composition typically will contain a higher amount of soap (e.g., the product of neutralizing a fatty acid with NaOH or similar).
• the leave-on dermatological composition according to the invention comprises one or more active dermatological ingredients.
• active dermatological ingredients are compounds that have a caring effect on the skin, whereby it is to be understood that the expression 'caring' should be interpreted broadly.
• the oils and emulsifiers discussed above may also qualify as an active dermatological ingredient.
• active dermatological ingredients include moisturizers, nourishing compounds, vitamins, anti-irritants, holding agents, anti-aging agents, slimming agents, exfoliants and anti-oxidants.
• the active ingredients are one or more selected from the group comprising of biosaccharide gum-1 , bisabolol, sodium PCA, urea, allantoin, hydrolyzed wheat protein, lactic acid, lysine, PCA, solanum lycopersicum extract, helianthus annuus seed oil, rosmarinus officinalis extract, prunus armeniaca kernel oil, citrus aurantium dulcis extract, tocopheryl acetate and panthenol.
• biosaccharide gum-1 bisabolol, sodium PCA, urea, allantoin, hydrolyzed wheat protein, lactic acid, lysine, PCA, solanum lycopersicum extract, helianthus annuus seed oil, rosmarinus officinalis extract, prunus armeniaca kernel oil, citrus aurantium dulcis extract, tocopheryl acetate and panthenol.
• the leave-on dermatological compositions according to the invention may also comprise one or more UV-filters, preferably selected from bis-ethylhexyloxyphenol methoxyphenyl triazine, octocrylene, methylene bis- benzotriazolyl tetramethylbutylphenol, ethylhexyl triazone, butyl methoxydibenzoylmethane, ethylhexyl salicylate, phenylbenzimidazole sulfonic acid and diethylhexyl butamido triazone.
• UV-filters preferably selected from bis-ethylhexyloxyphenol methoxyphenyl triazine, octocrylene, methylene bis- benzotriazolyl tetramethylbutylphenol, ethylhexyl triazone, butyl methoxydibenzoylmethane, ethylhexyl sal
• a dermatological composition contained in an aerosol according to the present invention may further comprise auxiliary ingredients such as co-emulsifiers, pH-adjusting agents, preservatives, perfumes, aroma's and rheological additives such as stabilizers, viscosity adjusting agents and film forming agents.
• auxiliary ingredients such as co-emulsifiers, pH-adjusting agents, preservatives, perfumes, aroma's and rheological additives such as stabilizers, viscosity adjusting agents and film forming agents.
• another aspect of the present invention is related to a method for filling the aerosol containers of the present invention.
• a container is provided, having a first chamber and a second chamber, the chambers being separated by a movable, gas-tight solid wall.
• a valve assembly comprising a valve and a disc is brought onto the second chamber of the aerosol container.
• the valve assembly is attached to the container with its disc, such that the second chamber of the aerosol container is closed.
• the one or more physical foaming agents are filled into the second chamber through the valve. Said foaming agents are filled as liquids.
• the dermatological composition is added thereto. Then the first chamber is pressurized and closed.
• Methods and apparatus for pressurizing the can, for bringing the valve assembly inside the aerosol container and attaching the disc to the can, and for through the valve filling of the foaming agents and the dermatological composition, are as such known in the art.
• a first advantageous embodiment of the present invention is related to a sunscreen formulation.
• This embodiment will be referred to as "sunscreen embodiment".
• the inventors found that when such a sunscreen formulation is applied to the skin as a rich foam, it can easily be spread out without missing any spots.
• the viscosity of the leave-on dermatological composition used in a formulation according to this embodiment is preferably between 50 and 20,000 mPa.s, more preferably between 100 and 15,000 mPa.s, most preferably between 400 and 13,000 mPa.s.
• sunscreen formulations according to this embodiment comprise from > 0 to 95 wt.% of one or more oils and active dermatological agents, from > 0 to 15 wt.% of one or more oil-in-water emulsifiers, from > 0 to 10 wt.% of one or more physical foaming agents, > 0 to 30 wt.% of one or more UV-filters, and water.
• sunscreen formulations according to this embodiment comprise from 1 to 50 wt.% of one or more oils and active dermatological agents, from 0.1 to 10 wt.% of one or more oil-in-water emulsifiers, from 0.5 to 5 wt.% of one or more physical foaming agents, 0.5 to 30 wt.% of one or more UV-filters, and water.
• said sunscreen formulations comprise 3.5 to 25 wt.% of the one or more oils and the active ingredients, 3 to 5.5 wt.% of the one or more oil-in-water emulsifiers, 3 to ⁇ 5 wt.% of the one or more physical foaming agents, 10 to 30 wt.% of the one or more UV-filters, and water.
• the one or more oils are preferably selected from C12-C15 alkyl benzoates, ethylhexyl cocoate, dicaprylyl carbonate, dibutyl adipate, cyclopentasiloxane and dimethicone.
• the one or more emulsifiers are preferably selected from sorbitan stearate, glyceryl stearate, peg-100 stearate, potassium cetyl phosphate, polysorbate 80, bis-peg/ppg-16/16 peg/ppg-16/16 dimethicone, acrylates/vinyl isodecanoate crosspolymer, ceteareth-20, acrylates/Cio-3o alkyl acrylates cross-polymer and laureth-7.
• the active ingredients are preferably selected from biosaccharide gum-1 , bisabolol, sodium PCA, urea, allantoin, hydrolyzed wheat protein, lactic acid, lysine, PCA, solanum lycopersicum extract, helianthus annuus seed oil, rosmarinus officinalis extract, prunus armeniaca kernel oil, citrus aurantium dulcis extract, tocopheryl acetate and panthenol.
• the one or more UV-filters are preferably selected from bis-ethylhexyloxyphenol methoxyphenyl triazine, octocrylene, methylene bis-benzotriazolyl tetramethylbutylphenol, ethylhexyl triazone, butyl methoxydibenzoylmethane, ethylhexyl salicylate,
• the one or more foaming agents are selected from propane, butane, isobutane and mixtures thereof.
• Another preferred embodiment is related to other skin care formulations such as tanning lotions, after-sun lotions and body lotions, wherein the choice of active
• Tanning lotions are used to improve tanning of the skin under influence of UV-radiation.
• these skin care formulation fulfil the same criteria and comprise the same ingredients as specified above under the sunscreen embodiment, the most relevant difference being the omission of the UV-filters. It is recognized that omitting one or more UV- filters from a composition might influence the stability of a composition. When needed, the amounts of the ingredients present in a skin care formulation of this embodiment can be adjusted to retain the stability of the formulation. A further stabilizer or further auxiliary agent can even be added to ensure the stability of the formulation.
• dermatological composition used in the present skin care formulation is preferably between 900 and 20,000 mPa.s, more preferably between 1 ,500 and 15,000 mPa.s, most preferably between 2,000 and 10,000 mPa.s.
• the leave-on dermatological composition is a baby care product such as a nappy rash cream comprising at least zinc oxide or tin dioxide as an active dermatological ingredient.
• baby care formulations according to this embodiment comprise from 0.1 to
• baby care formulations comprise 0.5 to 15 wt.% of zinc oxide or titanium dioxide, or a mixture of both, from 1 to 50 wt.% of one or more oils and further active dermatological agents, from 0.1 to 10 wt.% of one or more oil-in- water emulsifiers, from 0.5 to 5 wt.% of one or more physical foaming agents, and water.
• said baby care formulations comprise from 0.5 to 5 wt.% of zinc oxide or titanium dioxide, or a mixture of both, from 3.5 to 25 wt.% of the one or more oils and the further active ingredients, 3 to 5.5 wt.% of the one or more oil-in-water emulsifiers, from 3 to 5 wt.% of the one or more physical foaming agents, and water.
• the baby care formulations optionally comprise from > 0 to 30 wt.% of one or more UV-filters.
• the one or more oils can be mineral oils, lipids such as suitable esters, ethers, vegetable oils, fatty acids and phospholipids, or silicone moieties. Said oils are preferably selected from alkyl adipates, caprylic/capric triglyceride, ethylhexyl stearate, dicaprylyl carbonate, dicaprylyl ether, hydrogenated polydecene, pentaerythrityl tetracaprylate/caprate, cyclopentasiloxane, dimethicone.
• the one or more emulsifiers are preferably selected from sorbitan stearate, glyceryl stearate, peg-100 stearate, potassium cetyl phosphate, polysorbate 80, bis-peg/ppg-16/16 peg/ppg-16/16 dimethicone, acrylates/vinyl isodecanoate crosspolymer, ceteareth-20, acrylates/Cio-3o alkyl acrylates cross-polymer and laureth-7.
• the further active ingredients are selected from biosaccharide gum- 1 , bisabolol, sodium pea, urea, allantoin, hydrolyzed wheat protein, lactic acid, lysine, pea, solanum lycopersicum extract, helianthus annuus seed oil, rosmarinus officinalis extract, prunus armeniaca kernel oil, citrus aurantium dulcis extract.
• the one or more foaming agents are selected from propane, butane, isobutane and mixtures thereof.
• the viscosity preferably is not higher than 20,000 mPa.s, more preferably between 500 and 15,000 mPa.s, most preferably between 1 ,000 and 10,000 mPa.s.
• compositions A-G were prepared by mixing the ingredients as specified in table 1 (in weight per cent).
• table 1 dermatological compositions A-G: ingredients and their amounts (wt.%) formulation Skin Sun Sun Sun Sun Skin Skin type Care Care Care Care Care Care Care Care Care Care ingredients A B C D E F G
• the dynamic viscosity of the prepared compositions was measured using a Brookfield RV viscometer. Measured viscosities and relevant measurement conditions are listed in table 2.
• bag-on-valve aerosol containers were filled by first inserting about 3 wt.% of the one or more physical blowing agents and subsequently filling the compositions A-G into the container. After this, suitable actuators were attached to the aerosol containers.
• table 2 measured viscosity of A-G
• compositions A-G were discharged from the bag-on-valve aerosol containers by activating the actuator. All aerosol containers delivered a rich foam that did not drip from the skin and allowed for easy spreading.
• compositions H and J were so viscous that is was rather difficult for them to be supplied to the aerosol container in an efficient way. Moreover, it appeared that these compositions did not produce a satisfactorily foaming product. In contradistinction therewith, the compositions I and K could easily be filled into the aerosol containers and produced a rich foam that did not drip from the skin and allowed for easy spreading. This shows that also in the aerosol containers according to the present invention the formulations should have a viscosity according to the claims in order to provide a rich foam that does not drip and allows for easy spreading.

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