EP2934474A4 - MODULATION OF MELANOGENESIS BY TYROSINASE MODIFICATION BY PALMITOYLATION - Google Patents
MODULATION OF MELANOGENESIS BY TYROSINASE MODIFICATION BY PALMITOYLATIONInfo
- Publication number
- EP2934474A4 EP2934474A4 EP13864592.4A EP13864592A EP2934474A4 EP 2934474 A4 EP2934474 A4 EP 2934474A4 EP 13864592 A EP13864592 A EP 13864592A EP 2934474 A4 EP2934474 A4 EP 2934474A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- palmitoylation
- melanogenesis
- tyrosinase
- modulation
- modification
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/005—Enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/08—Preparations for bleaching the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/10—Preparations for permanently dyeing the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17166331.3A EP3207919A1 (en) | 2012-12-20 | 2013-12-12 | Palmitoylated peptides for reducing the appearance of melanin in skin or hair |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261740048P | 2012-12-20 | 2012-12-20 | |
PCT/US2013/074666 WO2014099609A1 (en) | 2012-12-20 | 2013-12-12 | Modulation of melanogenesis by modification of tyrosinase by palmitoylation |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP17166331.3A Division EP3207919A1 (en) | 2012-12-20 | 2013-12-12 | Palmitoylated peptides for reducing the appearance of melanin in skin or hair |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2934474A1 EP2934474A1 (en) | 2015-10-28 |
EP2934474A4 true EP2934474A4 (en) | 2016-10-12 |
Family
ID=50974888
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP13864592.4A Withdrawn EP2934474A4 (en) | 2012-12-20 | 2013-12-12 | MODULATION OF MELANOGENESIS BY TYROSINASE MODIFICATION BY PALMITOYLATION |
EP17166331.3A Withdrawn EP3207919A1 (en) | 2012-12-20 | 2013-12-12 | Palmitoylated peptides for reducing the appearance of melanin in skin or hair |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP17166331.3A Withdrawn EP3207919A1 (en) | 2012-12-20 | 2013-12-12 | Palmitoylated peptides for reducing the appearance of melanin in skin or hair |
Country Status (8)
Country | Link |
---|---|
US (4) | US20140178319A1 (ko) |
EP (2) | EP2934474A4 (ko) |
JP (2) | JP6246832B2 (ko) |
KR (2) | KR20150093844A (ko) |
CN (1) | CN104918602B (ko) |
AU (1) | AU2013363330B2 (ko) |
CA (1) | CA2895238C (ko) |
WO (1) | WO2014099609A1 (ko) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2934474A4 (en) * | 2012-12-20 | 2016-10-12 | Elc Man Llc | MODULATION OF MELANOGENESIS BY TYROSINASE MODIFICATION BY PALMITOYLATION |
WO2017178838A1 (en) * | 2016-04-13 | 2017-10-19 | University Of Dundee | Binding modulation |
CN106916203B (zh) * | 2017-03-29 | 2020-06-30 | 佛山科学技术学院 | 一种棕榈酰化七肽、及其纯化方法和应用 |
CN109453154A (zh) * | 2017-09-06 | 2019-03-12 | 上海交通大学医学院附属仁济医院 | 一种pd-l1的抑制剂及其制备方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6890954B1 (en) * | 1999-09-23 | 2005-05-10 | Marilyn D. Resh | Uses of 2-bromopalmitate in the treatment of autoimmune disease |
US20110044920A1 (en) * | 2009-08-07 | 2011-02-24 | Mary Kay Inc. | Topical skin care formulations |
US20110183914A1 (en) * | 2005-04-27 | 2011-07-28 | Rosemarie Osborne | Personal Care Compositions |
US20120156315A1 (en) * | 2010-12-17 | 2012-06-21 | Keimyung University Industry Academic Cooperation Foundation | Composition for Treating Vitiligo or Canities Comprising Extract from Sophora Japonica as Active Ingredient |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9212276D0 (en) * | 1992-06-10 | 1992-07-22 | Harper David R | Anti-viral agents |
US20030153619A1 (en) * | 2002-01-29 | 2003-08-14 | Hwang Cheng Shine | Reduction of hair growth |
FR2854897B1 (fr) * | 2003-05-12 | 2007-05-04 | Sederma Sa | Compositions cosmetiques ou dermopharmaceutiques pour reduire les signes du vieillissement cutane. |
US20060100146A1 (en) * | 2004-08-16 | 2006-05-11 | Sturley Stephen L | AWAT-related methods and articles |
US7875302B2 (en) * | 2004-12-14 | 2011-01-25 | Access Business Group International Llc | Methods of using grape seed extract to stimulate tyrosinase gene expression |
US8357360B2 (en) * | 2005-04-23 | 2013-01-22 | E-L Management Corp. | Cosmetic compositions containing an aqueous dispersion of silicone elastomers and methods of use |
US20080254055A1 (en) | 2007-04-11 | 2008-10-16 | John Erich Oblong | Compositions for Regulation of Hair Growth |
EP2014276A1 (en) * | 2007-06-20 | 2009-01-14 | Cognis IP Management GmbH | Cosmetic compositions comprising sclareolide and hesperidin methyl chalcone |
MX337830B (es) * | 2009-04-17 | 2016-03-16 | Lipotec Sa | Peptidos utiles en el tratamiento y/o cuidado de la piel y/o cabello y su uso en composiciones cosmeticas o farmaceuticas. |
FR2944435B1 (fr) * | 2009-04-17 | 2011-05-27 | Sederma Sa | Composition cosmetique comprenant de l'oridonine |
JP5956107B2 (ja) * | 2010-11-13 | 2016-07-20 | 学校法人昭和大学 | 皮膚および毛髪の黒化促進剤、その黒化促進剤を含む黒化促進用外用剤および黒化促進用飲食品 |
EP2934474A4 (en) * | 2012-12-20 | 2016-10-12 | Elc Man Llc | MODULATION OF MELANOGENESIS BY TYROSINASE MODIFICATION BY PALMITOYLATION |
-
2013
- 2013-12-12 EP EP13864592.4A patent/EP2934474A4/en not_active Withdrawn
- 2013-12-12 JP JP2015549496A patent/JP6246832B2/ja active Active
- 2013-12-12 CN CN201380067441.7A patent/CN104918602B/zh active Active
- 2013-12-12 KR KR1020157019032A patent/KR20150093844A/ko not_active Application Discontinuation
- 2013-12-12 AU AU2013363330A patent/AU2013363330B2/en active Active
- 2013-12-12 CA CA2895238A patent/CA2895238C/en active Active
- 2013-12-12 US US14/104,412 patent/US20140178319A1/en not_active Abandoned
- 2013-12-12 EP EP17166331.3A patent/EP3207919A1/en not_active Withdrawn
- 2013-12-12 KR KR1020177005427A patent/KR101870094B1/ko active IP Right Grant
- 2013-12-12 WO PCT/US2013/074666 patent/WO2014099609A1/en active Application Filing
-
2015
- 2015-03-31 US US14/675,321 patent/US20150283054A1/en not_active Abandoned
- 2015-03-31 US US14/675,361 patent/US20150283105A1/en not_active Abandoned
- 2015-03-31 US US14/675,247 patent/US9283166B2/en active Active
-
2016
- 2016-11-30 JP JP2016231907A patent/JP2017078074A/ja active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6890954B1 (en) * | 1999-09-23 | 2005-05-10 | Marilyn D. Resh | Uses of 2-bromopalmitate in the treatment of autoimmune disease |
US20110183914A1 (en) * | 2005-04-27 | 2011-07-28 | Rosemarie Osborne | Personal Care Compositions |
US20110044920A1 (en) * | 2009-08-07 | 2011-02-24 | Mary Kay Inc. | Topical skin care formulations |
US20120156315A1 (en) * | 2010-12-17 | 2012-06-21 | Keimyung University Industry Academic Cooperation Foundation | Composition for Treating Vitiligo or Canities Comprising Extract from Sophora Japonica as Active Ingredient |
Non-Patent Citations (5)
Title |
---|
ANAND K. GANESAN ET AL: "Genome-Wide siRNA-Based Functional Genomics of Pigmentation Identifies Novel Genes and Pathways That Impact Melanogenesis in Human Cells", PLOS GENETICS, vol. 4, no. 12, 5 December 2008 (2008-12-05), pages e1000298, XP055110458, DOI: 10.1371/journal.pgen.1000298 * |
DATABASE GNPD [online] MINTEL; 30 November 2012 (2012-11-30), ANONYMOUS: "Radiant night peel 15% - intensive skin renewal treatment", XP002761077, retrieved from www.gnpd.com Database accession no. 1857082 * |
DATABASE GNPD [online] MINTEL; 31 January 2006 (2006-01-31), ANONYMOUS: "Skin brightening daily moisturiser SPF 30", XP002761076, retrieved from www.gnpd.com Database accession no. 427648 * |
DRAPER JEREMIAH M ET AL: "Palmitoyl acyltransferase assays and inhibitors (Review)", MOLECULAR MEMBRANE BIOLOGY, TAYLOR AND FRANCIS, GB, vol. 26, no. 1-2, 1 January 2009 (2009-01-01), pages 5 - 13, XP009135881, ISSN: 0968-7688, DOI: 10.1080/09687680802683839 * |
See also references of WO2014099609A1 * |
Also Published As
Publication number | Publication date |
---|---|
CN104918602A (zh) | 2015-09-16 |
US20150283054A1 (en) | 2015-10-08 |
US20150283105A1 (en) | 2015-10-08 |
KR101870094B1 (ko) | 2018-06-22 |
AU2013363330B2 (en) | 2016-04-14 |
EP2934474A1 (en) | 2015-10-28 |
EP3207919A1 (en) | 2017-08-23 |
WO2014099609A1 (en) | 2014-06-26 |
KR20170024166A (ko) | 2017-03-06 |
CA2895238C (en) | 2018-01-09 |
JP2016504997A (ja) | 2016-02-18 |
CN104918602B (zh) | 2018-05-01 |
KR20150093844A (ko) | 2015-08-18 |
US20150283104A1 (en) | 2015-10-08 |
AU2013363330A1 (en) | 2015-07-30 |
CA2895238A1 (en) | 2014-06-26 |
US9283166B2 (en) | 2016-03-15 |
JP2017078074A (ja) | 2017-04-27 |
US20140178319A1 (en) | 2014-06-26 |
JP6246832B2 (ja) | 2017-12-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20150707 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
|
DAX | Request for extension of the european patent (deleted) | ||
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 31/20 20060101ALI20160602BHEP Ipc: A61K 38/00 20060101ALI20160602BHEP Ipc: A61K 38/06 20060101ALI20160602BHEP Ipc: A61Q 19/02 20060101ALI20160602BHEP Ipc: A61K 8/36 20060101AFI20160602BHEP Ipc: A61K 8/64 20060101ALI20160602BHEP Ipc: A61Q 5/08 20060101ALI20160602BHEP Ipc: A61Q 5/10 20060101ALI20160602BHEP Ipc: A61K 38/08 20060101ALI20160602BHEP |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 38/06 20060101ALI20160901BHEP Ipc: A61K 8/64 20060101ALI20160901BHEP Ipc: A61K 31/20 20060101ALI20160901BHEP Ipc: A61K 38/00 20060101ALI20160901BHEP Ipc: A61Q 5/08 20060101ALI20160901BHEP Ipc: A61K 8/36 20060101AFI20160901BHEP Ipc: A61Q 19/02 20060101ALI20160901BHEP Ipc: A61K 38/08 20060101ALI20160901BHEP Ipc: A61Q 5/10 20060101ALI20160901BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20160913 |
|
17Q | First examination report despatched |
Effective date: 20181024 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20190504 |