EP2885079A1 - Pipette mit elektromotorisch angetriebenem kolben und magnetfeld-abschirmung - Google Patents
Pipette mit elektromotorisch angetriebenem kolben und magnetfeld-abschirmungInfo
- Publication number
- EP2885079A1 EP2885079A1 EP13750565.7A EP13750565A EP2885079A1 EP 2885079 A1 EP2885079 A1 EP 2885079A1 EP 13750565 A EP13750565 A EP 13750565A EP 2885079 A1 EP2885079 A1 EP 2885079A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- cylinder
- piston
- pipetting
- magnet assembly
- pipetting device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000005291 magnetic effect Effects 0.000 title claims abstract description 35
- 230000008878 coupling Effects 0.000 claims abstract description 24
- 238000010168 coupling process Methods 0.000 claims abstract description 24
- 238000005859 coupling reaction Methods 0.000 claims abstract description 24
- 239000012530 fluid Substances 0.000 claims abstract description 11
- 239000000463 material Substances 0.000 claims description 14
- 239000011159 matrix material Substances 0.000 claims description 13
- 239000002131 composite material Substances 0.000 claims description 12
- 239000000945 filler Substances 0.000 claims description 10
- 230000015572 biosynthetic process Effects 0.000 claims description 9
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims description 8
- 230000005294 ferromagnetic effect Effects 0.000 claims description 8
- 230000000712 assembly Effects 0.000 claims description 7
- 238000000429 assembly Methods 0.000 claims description 7
- 230000000694 effects Effects 0.000 claims description 7
- 239000002245 particle Substances 0.000 claims description 7
- 239000003302 ferromagnetic material Substances 0.000 claims description 6
- 239000011248 coating agent Substances 0.000 claims description 5
- 238000000576 coating method Methods 0.000 claims description 5
- 229910000831 Steel Inorganic materials 0.000 claims description 4
- 229910017052 cobalt Inorganic materials 0.000 claims description 4
- 239000010941 cobalt Substances 0.000 claims description 4
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 claims description 4
- 229910052759 nickel Inorganic materials 0.000 claims description 4
- 239000010959 steel Substances 0.000 claims description 4
- 239000004020 conductor Substances 0.000 claims description 2
- 230000001617 migratory effect Effects 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
- 230000008054 signal transmission Effects 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 6
- 229910002804 graphite Inorganic materials 0.000 description 6
- 239000010439 graphite Substances 0.000 description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 4
- 238000001746 injection moulding Methods 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 239000003570 air Substances 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 2
- 238000010292 electrical insulation Methods 0.000 description 2
- 230000004907 flux Effects 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000377 silicon dioxide Substances 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000012080 ambient air Substances 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000004922 lacquer Substances 0.000 description 1
- 238000010002 mechanical finishing Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
- B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
- B01L3/0227—Details of motor drive means
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
- H01F7/00—Magnets
- H01F7/06—Electromagnets; Actuators including electromagnets
- H01F7/08—Electromagnets; Actuators including electromagnets with armatures
- H01F7/16—Rectilinearly-movable armatures
- H01F7/1607—Armatures entering the winding
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
Definitions
- the present invention relates to a pipetting device with a piston-cylinder system comprising a cylinder extending along a cylinder axis, a piston and a working space bounded by the cylinder and the piston and filled with a working fluid for changing a pressure of the working fluid at a Coupling of a pipetting tip formed coupling point, which is pressure-transmitting connected to the working space, by relative movement of the piston relative to the cylinder along a relative movement path, wherein the piston linear motor to the relative movement is driven relative to the cylinder and for this purpose has at least one piston magnet arrangement, and further at least one cylinder magnet arrangement is provided on the cylinder, wherein at least one magnet arrangement comprising a piston magnet arrangement and a cylinder magnet arrangement comprises a series of electromagnets which are generated by means of a control device of the pipetting device a magnetic field traveling along the relative movement path can be energized, thereby providing the magnetic driving force necessary to effect the relative movement.
- the pipetting piston can be driven linearly relative to the cylinder for relative movement.
- This basically very advantageous drive method which, for example, by appropriate wiring of the series of electromagnets such, that their magnetic field travels along the relative trajectory and “drives" the magnetically-coupled other magnet assembly, allows immediate movement of the piston relative to the cylinder without the need for linkage or gearboxes in the prior art, as in the present invention
- the cylinder magnet arrangement is designed and provided for common movement with the cylinder, wherein with respect to a device frame of the pipetting device, the cylinder is usually mounted fixed to the frame, so that the cylinder magnet arrangement in the Rule is fixed to the frame.
- the object of the present invention is therefore to further develop the generic pipetting device known from the prior art in such a way that the magnetic field influence emanating from a pipetting channel is reduced to the environment outside the pipetting channel or even completely eliminated.
- This object is achieved by a pipetting device of the type mentioned above, which has a magnetic shield radially outward of the piston magnet assembly and the cylinder magnet arrangement, which in the radially outside of the location of the shield existing magnetic field, which starts from at least one magnet assembly of the piston magnet assembly and cylinder magnet assembly in comparison weakens to a condition without shielding.
- the reference state for judging whether a component is an effective magnetic shield is the state of the same device without the component concerned.
- Effective magnetic shielding can be achieved by having the shield comprise a shielding member with a ferromagnetic material.
- the shielding component may also comprise other material. To achieve the advantageous shielding effect is only sufficient that it has ferromagnetic material, since this has a lower magnetic resistance than other materials, including the ambient air, so that magnetic flux preferably takes place through the ferromagnetic material.
- the shielding component can surround a device frame-fixed magnet arrangement of piston and cylinder magnet arrangement at least along an axial section thereof.
- the greater the common axial area the higher the shielding effect over which the device stellfeste magnet assembly and the shielding member extend together.
- the shielding member surrounds the device frame fixed magnet assembly along its entire axial extent.
- the above orientation on the device frame fixed magnet arrangement is chosen because it is fixed in this attachment location and their Clearreckungin.
- the relative to a device frame movable magnet assembly usually the piston magnet assembly, moves in operation relative to the device frame so that it occupies different positions at different times and is located at different locations.
- the complete shielding of the magnetic field which originates from the magnet arrangement that is movable relative to the device frame can be thought of, in that the shielding component surrounds the entire relative movement path of the two magnet arrangements, so that particularly preferably each magnet arrangement is located in the axial extension region of the shielding component at all times ,
- the shielding component surrounds the device frame-fixed magnet arrangement in the circumferential direction as far as possible.
- the shielding member surrounds the device frame fixed magnet assembly at least half its circumference. This considerably facilitates the mounting of the shielding component, since it can simply be plugged with its opening side onto a pipetting channel and its magnet arrangements orthogonal to the cylinder axis.
- the shielding component therefore particularly preferably surrounds the device frame-fixed magnet arrangement around its complete constant scope around. Then, the assembly can be carried out by sliding the Ablebauteils on the pipetting along its cylinder axis.
- An easy-to-manufacture shape of the Ablebauteils represents a U-profile, which can be achieved by bending a sheet around an axis in a simple and cost-effective manner.
- the shielding component has a symmetrical construction with respect to its direction of longitudinal extension, that is to say generally along the cylinder axis. This can be realized, for example, by shielding components which, when viewing their cross-section in a sectional plane orthogonal to the cylinder axis, have a polygonal or / and a part-circular or / and a circular contour.
- the shielding component also surrounds the electromagnetic magnet arrangement for the above-mentioned reasons, in order to avoid an undesirably high heating of the electromagnetic magnet arrangement, it may be provided that the shielding component has at least one opening passing radially through it, such as a hole or slot, in particular one along the cylinder axis extending slot, has. Warm air can thus escape from the volume surrounded by the shielding component through such openings and can flow in cool air, whether by natural convection or by forced convection by means of a fan or the like. Then, when the hole or slit extends along the cylinder axis, cooling can be achieved over the largest possible axial area of the pipetting device, since as a rule magnet arrangements also run along the cylinder axis.
- the one-piece design but apart from the basic shape of the Ablebauteils, can be facilitated by the fact that the Ablebauteil comprises a composite material with a matrix material and ferromagnetic filler.
- the filler material may be spherical or / and fibrous and may be held in place by the matrix material.
- a castable plastic or generally a pourable material can be used, so that the composite material can be introduced in the castable state of the matrix material mixed with filler therein in a mold and thus brought into the desired shape.
- the use of injection molding processes for producing the shielding component is particularly preferred, so that the matrix material may be a preferably thermoplastic.
- the shielding component may have other materials in addition to the composite material, but is preferably formed entirely from such a composite material due to the preferred injection molding process.
- the spherical or / and fiber-shaped or / and other -wavelike particles of the ferromagnetic filler material may be provided with an electrically insulating coating.
- a coating may, for example, be a correspondingly electrically insulating lacquer which surrounds the individual particles of the ferromagnetic filling material. Insulating wraps of silica filler particles have proven particularly advantageous.
- the use of a composite material of matrix material and ferromagnetic filler for the production of the shielding allows a mechanically stable, high-strength component, which can be brought into any desired shape by injection molding and, if necessary, can be post-machined mechanically after removal from the injection mold.
- the mechanically often critical attachment of a coupling formation to the, preferably detachable, coupling of pipette tips thereto on the cylinders, which are often made of glass can be omitted.
- the coupling formation can be provided directly on the shielding component.
- Particularly preferred is the at least partially integral formation of coupling formation and Ablebauteil, for example by injection molding and, but not necessarily, with mechanical finishing. If the coupling formation requires moving parts, they can be mounted on a coupling forming portion formed integrally with the shielding member.
- At least one further component can be cast directly into the shielding component.
- This may for example be a sensor, for example a temperature sensor for monitoring the temperature of one or more components of the pipetting device, in particular the pipetting channel, and / or it may be a proximity sensor which can detect the presence or absence of the piston at a predetermined position.
- one or more signal and / or energy transmission lines can be cast into the shielding component, for example for supplying electrical energy to the electromagnets of the at least one electromagnetic magnet arrangement. Even the electromagnets can be cast into the shielding component.
- the proportion of filling material in the matrix material is dimensioned such that under the predetermined intended use of magnets in the magnet assemblies, the shielding member is at least partially magnetically in saturation.
- the shielding component comprises steel and / or cobalt and / or nickel or is formed from steel and / or cobalt and / or nickel.
- the shielding component may be movable with the piston, such a device of a movable shielding component requires considerable manufacturing and assembly costs. Therefore, it is preferable that the shielding member is fixed to the apparatus rack, as stated above in connection with the linear overlap of the shielding member with the apparatus frame fixed magnet assembly.
- the piston in the cylinder can perform a relative movement relative to the cylinder without interference
- the cylinder magnet arrangement is arranged radially outside of the cylinder relative to the cylinder axis passing through the cylinder.
- the piston at least in sections from graphite-containing material, in particular from graphite itself, so that the graphite-containing portions of the piston can be in sliding engagement directly on an inner surface of the cylinder.
- a self-lubricating property of graphite can be utilized to facilitate the relative movement of the piston relative to the cylinder.
- Magnets of the piston magnet arrangement can be provided in the piston.
- the cylinder magnet assembly is preferably the electromagnetic magnet assembly.
- the cylinder magnet arrangement has a plurality of conductor coils following one another along the cylinder axis and / or that the piston magnet arrangement has a plurality of permanent magnets which follow one another along the cylinder axis.
- the pipetting device it is possible in a particularly simple manner to design the pipetting device such that it has a plurality of pipetting channels which can be operated separately from one another. This considerably facilitates the execution of different metering tasks in a metering liquid absorption, metering liquid transport and metering liquid delivery process.
- different amounts of a dosing liquid can be aspirated and / or dispensed from different pipetting channels of one and the same pipetting device.
- the present invention therefore also encompasses the idea of providing a plurality of piston-cylinder systems, each having a cylinder axis, to a generic pipetting device or to a pipetting device of the present invention, wherein the control device is designed to provide the magnet arrangements comprising at least one electromagnet of at least two piston-cylinder systems, preferably at the same time differently from all piston-cylinder systems to induce differently in at least two, preferably in all piston-cylinder systems simultaneously causing different relative movements of the piston and cylinder of the respective system.
- Fig. 1 is a rough cross-sectional schematic view of an embodiment of a pipetting device according to the invention with two pipetting example by way of example in longitudinal section.
- FIG. 1 an embodiment of a pipetting device according to the invention only roughly schematically illustrated in longitudinal section is generally denoted by 10.
- the pipetting device may comprise a plurality of pipetting channels, in the example illustrated, for example, the pipetting channels 12 and 14. Since the pipetting channels 12 and 14 are configured substantially identically, only the pipetting channel 12 will be described below as representative of both pipetting channels. If the pipetting channels 12 and 14 differ in relevant features, will be discussed separately below.
- the pipetting channel 12 extends along a Pipettierkanalachse P, which preferably extends preferably rectilinear.
- the pipetting channel 12 comprises a piston-cylinder system 16, with a cylinder 18, in which a piston 20, preferably at least partially made of graphite or graphite-containing material, relative to the cylinder 18 along the Pipettierkanalachse P is slidably received.
- the Pipettierkanalachse P coincides in the present example with the cylinder axis Z of the cylinder 18 together.
- a number of permanent magnets 22 may be provided, which form a piston magnet assembly.
- the magnets 22 are preferably arranged consecutively in the direction of the pipetting channel axis P, which is preferably also a piston longitudinal axis K, in order to obtain a piston 20 of small diameter with respect to the pipetting channel axis P.
- the entirety of the permanent magnets 22 of a piston 20 thus forms a piston magnet arrangement 24.
- the magnets 22 of the piston magnet assembly 24 may be separated from each other by spacers 25.
- the cylinder 18 is preferably surrounded radially in relation to the Pipettierkanalachse P outside by a series of magnets 26, which are preferably also along the Pipettierkanalachse P successively, particularly preferably equidistant from each other, are arranged.
- the magnets 26 are Eiektromagnete, so that they can be energized by a control device 28.
- the control device 28 can be designed to be the Eiektromagnete 26, which a cylinder ma- To energize gnetan extract 30 to energize such that their magnetic field along the Pipettierkanalachse migrates, so that by the wandering magnetic field of the electromagnets 26, the magnetic field preferably designed as permanent magnets 22 magnets of the piston magnet assembly 24 and with these the piston 20 for relative movement relative to the cylinder 18 driven become.
- the electromagnets 26 are preferably arranged identically and equidistant from each other along the pipetting channel axis P.
- Ablebauteil 32 Radially outside the cylinder 18 and the cylinder magnet assembly 30 is a, preferably injection molded, Ablebauteil 32 is provided which surrounds the magnets 22 and 26 of the two magnet assemblies 24 and 30 radially outward, and which also radially into the axial spaces between two immediately axially adjacent magnets 26th the cylinder magnet assembly 30 protrudes.
- the shielding component 32 can be formed from a composite material comprising a pourable, in particular injection-moldable matrix material into which ferromagnetic particles, which can have a spherical shape and / or a fiber shape, can be incorporated.
- the particles of ferromagnetic filler are preferably surrounded by an electrically insulating coating, for example of silica.
- the filling degree of the composite material for the shielding member 32 is so high that filler bridges form, so that sufficient electrical insulation by the matrix material is not necessarily ensured. However, the electrical insulation can be ensured by said coating.
- the Ablebauteil 32 which is preferably integrally formed so that the magnets 26 can be poured with their signal and / or energy transmission lines in the manufacture of Ablebauteils 32 in this can not only be achieved that radially outward of the two magnet assemblies 24 and 30, a significantly reduced magnetic field is measurable compared to the state of the same pipetting apparatus without the shielding member 32.
- the magnetic flux return achieved with the shielding member 32 can increase the efficiency of the linear motor driving means formed by the magnet assemblies 24 and 30.
- the shielding component 32 effecting a magnetic return a higher driving force acting on the piston 20 can be exerted on the magnets 26 with the same amount of power fed into the magnets than if the shielding component 32 were not present.
- a coupling device 34 may be provided, which carries a coupling formation 36 for coupling a pipetting tip 38 thereto.
- the coupling formation 36 can be configured in a manner known per se.
- the primary shaping of the shielding component 32 and its arrangement radially outward on the cylinder 18 advantageously allow the attachment of the coupling component 34 to the shielding component 32.
- an attachment component 40 can be interposed, which connects the coupling component 34 to the shielding component 32.
- the coupling component 34 may be formed at least partially in one piece with the shielding component 32.
- the cylinder 18 and the piston 20 define a working space 42 filled with working fluid, typically air or another gas, which has a metering space via a connecting channel 44 in the coupling component 34 46 can be fluid dynamically in connection with a pipetting tip 38 that can preferably be detachably connected to the coupling component 34.
- working fluid typically air or another gas
- the control device 28 which can preferably control the electromagnets 26 of all the pipetting channels 12 and 14 of one and the same pipetting device 10, is advantageously designed to supply the cylinder magnet arrangement 30 of the pipetting channel 12 and the cylinder magnet arrangement of the pipetting channel 14 separately from each other in order to feed into the pipetting channels to be able to cause different piston relative movements at the same time. This preferably continues with the increase in the number of pipetting channels of the pipetting device 10. More preferably, each cylinder magnet assembly 30 of a pipetting channel of the pipetter 10 may be operated separately from any other cylinder magnet assembly.
- pipetting channels of a pipetting device 10 into blocks of common, coinciding relative movement, for example in rows and / or columns, assuming the known and advantageous matrix arrangement of pipetting channels in rows and columns.
- Such a separate control of pipetting channels for effecting an individual relative movement of piston and cylinder is advantageous not only in linear motor driven pipetting channels, as shown in Figure 1, but can also in conventional mechanical, such as electric motor and gearbox, driven piston of a Lakanali- gene pipetting advantageous.
Landscapes
- Physics & Mathematics (AREA)
- Electromagnetism (AREA)
- Engineering & Computer Science (AREA)
- Power Engineering (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Linear Motors (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
Description
Claims
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17167647.1A EP3216524B1 (de) | 2012-08-17 | 2013-08-16 | Pipette mit einer mehrzahl von unabhängig voneinander elektromotorisch angetriebenen kolben |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102012214677.6A DE102012214677A1 (de) | 2012-08-17 | 2012-08-17 | Pipette mit elektromotorisch angetriebenem Kolben und Magnetfeldabschirmung |
PCT/EP2013/067179 WO2014027100A1 (de) | 2012-08-17 | 2013-08-16 | Pipette mit elektromotorisch angetriebenem kolben und magnetfeld-abschirmung |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP17167647.1A Division EP3216524B1 (de) | 2012-08-17 | 2013-08-16 | Pipette mit einer mehrzahl von unabhängig voneinander elektromotorisch angetriebenen kolben |
EP17167647.1A Division-Into EP3216524B1 (de) | 2012-08-17 | 2013-08-16 | Pipette mit einer mehrzahl von unabhängig voneinander elektromotorisch angetriebenen kolben |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2885079A1 true EP2885079A1 (de) | 2015-06-24 |
EP2885079B1 EP2885079B1 (de) | 2017-10-18 |
Family
ID=49000485
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP13750565.7A Active EP2885079B1 (de) | 2012-08-17 | 2013-08-16 | Pipette mit elektromotorisch angetriebenem kolben und magnetfeld-abschirmung |
EP17167647.1A Active EP3216524B1 (de) | 2012-08-17 | 2013-08-16 | Pipette mit einer mehrzahl von unabhängig voneinander elektromotorisch angetriebenen kolben |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP17167647.1A Active EP3216524B1 (de) | 2012-08-17 | 2013-08-16 | Pipette mit einer mehrzahl von unabhängig voneinander elektromotorisch angetriebenen kolben |
Country Status (5)
Country | Link |
---|---|
EP (2) | EP2885079B1 (de) |
DE (1) | DE102012214677A1 (de) |
ES (1) | ES2705438T3 (de) |
NO (1) | NO2925906T3 (de) |
WO (1) | WO2014027100A1 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10493444B2 (en) | 2015-10-13 | 2019-12-03 | Roche Molecular Systems, Inc. | Pipetting device for an apparatus for processing a sample or reagent, apparatus for processing a sample or reagent and method for pipetting a sample or reagent |
DE102016220425A1 (de) * | 2016-10-18 | 2018-04-19 | Hamilton Bonaduz Ag | Pipettiervorrichtung mit einfach austauschbarem Magnetkolben |
DE102016220424A1 (de) * | 2016-10-18 | 2018-04-19 | Hamilton Bonaduz Ag | Permanentmagnetische Kolbenbaugruppe mit einem Permanentmagnetanordnungen aufnehmenden Außenskelett für eine Pipettiervorrichtung |
DE102017201114A1 (de) | 2017-01-24 | 2018-07-26 | Hamilton Bonaduz Ag | Pipettiervorrichtung zur impulsartigen Pipettierung mit einer basierend auf einer Erfassung des Arbeitsgasdrucks geregelten Pipettierkolbenbewegung |
DE102017115796A1 (de) * | 2017-07-13 | 2019-01-17 | Hamilton Bonaduz Ag | Integrierte Motorkassette zum Anschluss an und zur Verwendung in einem Pipettiersystem, Pipettiersystem, und Verfahren zum Austauschen einer integrierten Motorkassette eines Pipettiersystems |
DE102017220892A1 (de) * | 2017-11-22 | 2019-05-23 | Hamilton Bonaduz Ag | Pipettiervorrichtung mit doppelseitig nutzbarer Stator-Magnetanordnung als Teil eines linearmotorischen Antriebs einer Pipettiereinheit |
DE102018211497A1 (de) * | 2018-07-11 | 2020-01-16 | Hamilton Bonaduz Ag | Pipettiervorrichtung zur impulsartigen Pipettierung mit einer basierend auf einer Erfassung des Arbeitsgasdrucks geregelten Pipettierkolbenbewegung |
NL1043014B9 (en) * | 2018-09-27 | 2020-07-22 | Buxenus V O F | Add-on device for attachment on a suction device |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH657275A5 (en) * | 1982-05-19 | 1986-08-29 | Sulzer Ag | Medicament dispenser |
US6669909B2 (en) * | 2001-03-26 | 2003-12-30 | Allegro Technologies Limited | Liquid droplet dispensing |
WO2003041474A1 (fr) * | 2001-11-09 | 2003-05-15 | Tdk Corporation | Element magnetique composite, feuille absorbant les ondes electromagnetiques, procede de production d'un article en feuille, et procede de production d'une feuille absorbant les ondes electromagnetiques |
US6936763B2 (en) * | 2002-06-28 | 2005-08-30 | Freescale Semiconductor, Inc. | Magnetic shielding for electronic circuits which include magnetic materials |
CA2533087A1 (fr) * | 2003-06-17 | 2005-01-27 | Moussa Hoummady | Dispositif de prelevement et de depot de gouttelettes d'au moins un liquide, procede de mise en oeuvre de ce dispositif, ainsi que systeme d'asservissement pour ce procede |
JP4966913B2 (ja) * | 2007-05-15 | 2012-07-04 | 株式会社日立ハイテクノロジーズ | 液体分注装置 |
DE102010000690A1 (de) | 2010-01-05 | 2011-07-07 | Hamilton Bonaduz Ag | Dosiervorrichtung und Dosierverfahren |
DE102010017279A1 (de) * | 2010-03-31 | 2011-10-06 | Universität Regensburg | Vorrichtung zum Erzeugen von Drücken in Probenbehältern |
-
2012
- 2012-08-17 DE DE102012214677.6A patent/DE102012214677A1/de not_active Withdrawn
-
2013
- 2013-08-16 ES ES17167647T patent/ES2705438T3/es active Active
- 2013-08-16 WO PCT/EP2013/067179 patent/WO2014027100A1/de active Application Filing
- 2013-08-16 EP EP13750565.7A patent/EP2885079B1/de active Active
- 2013-08-16 EP EP17167647.1A patent/EP3216524B1/de active Active
- 2013-10-24 NO NO13857823A patent/NO2925906T3/no unknown
Non-Patent Citations (2)
Title |
---|
None * |
See also references of WO2014027100A1 * |
Also Published As
Publication number | Publication date |
---|---|
ES2705438T8 (es) | 2019-07-04 |
EP3216524B1 (de) | 2018-11-07 |
EP3216524A1 (de) | 2017-09-13 |
WO2014027100A1 (de) | 2014-02-20 |
DE102012214677A1 (de) | 2014-02-20 |
EP2885079B1 (de) | 2017-10-18 |
ES2705438T3 (es) | 2019-03-25 |
NO2925906T3 (de) | 2018-02-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP2885079B1 (de) | Pipette mit elektromotorisch angetriebenem kolben und magnetfeld-abschirmung | |
EP4118358A1 (de) | Magnetorheologische bremseinrichtung | |
DE102014206635A1 (de) | Elektromagnetischer aktuator | |
DE102005019112A1 (de) | Kombinationsantrieb mit Hybridreluktanzmotor | |
DE102010002109A1 (de) | Sensoranordnung | |
EP3025358B1 (de) | Elektromagnetische stellvorrichtung und system zur verstellung einer funktionalität eines kraftfahrzeugaggregats | |
EP3191695B1 (de) | Elektromagnetische stellvorrichtung | |
DE102014105677A1 (de) | Drehwellenartiger Linearantriebsmotor und drehwellenartige Linearantriebsmotor-Einheit | |
DE102011103169A1 (de) | Elektromagnetischer Antrieb, Antriebsanlage und deren Verwendung | |
WO2015135814A2 (de) | Bistabiler elektromagnetischer aktuator und chirurgisches instrument | |
DE19838171A1 (de) | Elektromotor mit Bremse | |
DE102016125137A1 (de) | Mehrstellungszylinder | |
DE19900788B4 (de) | Antriebsvorrichtung | |
DE202008000318U1 (de) | Nadelverschlussdüse mit verbesserter Hebelanlenkung | |
DE102013111932A1 (de) | Behälterbehandlungsanlage und Verfahren zum Verstellen eines Geländers einer Behälterbehandlungsanlage | |
EP2735429A1 (de) | Behältnisbehandlungseinrichtung mit Reckeinrichtung | |
DE102008003210B4 (de) | Druckventil, insbesondere mit vorteilhafter elektrischer Kontaktführung | |
DE102021001273A1 (de) | Magnetschienenbremse mit im oder am Betätigungszylinder verbauter Hochlagenerkennung | |
DE102013203066A1 (de) | Transportvorrichtung und Verfahren zum Betrieb der Transportvorrichtung | |
DE102016108612A1 (de) | Bolzenschweißpistole | |
WO2015185362A1 (de) | Drehgestell für einen schienenfahrzeugwagen | |
EP2176156A1 (de) | Vorrichtung zum schneiden eines fadenförmigen körpers | |
DE102019120069A1 (de) | Anschlagmodul | |
EP2686853A1 (de) | Elektromagnetische aktuatorvorrichtung | |
DE19704695A1 (de) | Elektromagnetischer Teleskopf-Linearantrieb |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20150126 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: LIPPUNER, STEFAN Inventor name: KIRSTE, VINZENZ Inventor name: CATTANEO, HEIDI Inventor name: SUTER, MARIO |
|
DAX | Request for extension of the european patent (deleted) | ||
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
INTG | Intention to grant announced |
Effective date: 20170504 |
|
GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: HAMILTON BONADUZ AG |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D Free format text: NOT ENGLISH |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP Ref country code: CH Ref legal event code: NV Representative=s name: E. BLUM AND CO. AG PATENT- UND MARKENANWAELTE , CH |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: REF Ref document number: 937473 Country of ref document: AT Kind code of ref document: T Effective date: 20171115 Ref country code: IE Ref legal event code: FG4D Free format text: LANGUAGE OF EP DOCUMENT: GERMAN |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R096 Ref document number: 502013008613 Country of ref document: DE |
|
REG | Reference to a national code |
Ref country code: NL Ref legal event code: FP |
|
REG | Reference to a national code |
Ref country code: SE Ref legal event code: TRGR |
|
REG | Reference to a national code |
Ref country code: NO Ref legal event code: T2 Effective date: 20171018 |
|
REG | Reference to a national code |
Ref country code: LT Ref legal event code: MG4D |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: ES Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 Ref country code: LT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 Ref country code: FI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: RS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 Ref country code: BG Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20180118 Ref country code: HR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 Ref country code: IS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20180218 Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20180119 Ref country code: LV Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R082 Ref document number: 502013008613 Country of ref document: DE Representative=s name: RUTTENSPERGER LACHNIT TROSSIN GOMOLL PATENT- U, DE Ref country code: DE Ref legal event code: R082 Ref document number: 502013008613 Country of ref document: DE Representative=s name: RUTTENSPERGER LACHNIT TROSSIN GOMOLL, PATENT- , DE |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 6 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R097 Ref document number: 502013008613 Country of ref document: DE |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: CZ Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 Ref country code: SK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 Ref country code: DK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 Ref country code: EE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 Ref country code: SM Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 Ref country code: PL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 Ref country code: RO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 |
|
26N | No opposition filed |
Effective date: 20180719 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MC Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20180816 |
|
REG | Reference to a national code |
Ref country code: BE Ref legal event code: MM Effective date: 20180831 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20180831 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: TR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: HU Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO Effective date: 20130816 Ref country code: PT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MK Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20171018 Ref country code: CY Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: AL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171018 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: NL Payment date: 20220721 Year of fee payment: 10 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: SE Payment date: 20220721 Year of fee payment: 10 Ref country code: NO Payment date: 20220721 Year of fee payment: 10 Ref country code: IE Payment date: 20220721 Year of fee payment: 10 Ref country code: AT Payment date: 20220721 Year of fee payment: 10 |
|
P01 | Opt-out of the competence of the unified patent court (upc) registered |
Effective date: 20230521 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GB Payment date: 20230720 Year of fee payment: 11 Ref country code: CH Payment date: 20230902 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: FR Payment date: 20230720 Year of fee payment: 11 Ref country code: DE Payment date: 20230720 Year of fee payment: 11 |
|
REG | Reference to a national code |
Ref country code: NL Ref legal event code: MM Effective date: 20230901 |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: MM01 Ref document number: 937473 Country of ref document: AT Kind code of ref document: T Effective date: 20230816 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: AT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20230816 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: AT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20230816 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: NL Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20230901 |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: MM4A |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20230817 Ref country code: NO Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20230831 Ref country code: NL Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20230901 |