EP2872415B1 - Improved child-resistant cap for liquid medicaments - Google Patents

Improved child-resistant cap for liquid medicaments Download PDF

Info

Publication number
EP2872415B1
EP2872415B1 EP13816761.4A EP13816761A EP2872415B1 EP 2872415 B1 EP2872415 B1 EP 2872415B1 EP 13816761 A EP13816761 A EP 13816761A EP 2872415 B1 EP2872415 B1 EP 2872415B1
Authority
EP
European Patent Office
Prior art keywords
cap
lugs
shoulder
outer cap
lug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP13816761.4A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP2872415A4 (en
EP2872415A1 (en
Inventor
John Buehler
John Daly
Kevin Diplacido
Redd HAROLD
David KERSHNER
David Manera
Timothy STANGLE
Russ GRANATO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Comar Inc
Original Assignee
Comar Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Comar Inc filed Critical Comar Inc
Publication of EP2872415A1 publication Critical patent/EP2872415A1/en
Publication of EP2872415A4 publication Critical patent/EP2872415A4/en
Application granted granted Critical
Publication of EP2872415B1 publication Critical patent/EP2872415B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D50/00—Closures with means for discouraging unauthorised opening or removal thereof, with or without indicating means, e.g. child-proof closures
    • B65D50/02—Closures with means for discouraging unauthorised opening or removal thereof, with or without indicating means, e.g. child-proof closures openable or removable by the combination of plural actions
    • B65D50/04—Closures with means for discouraging unauthorised opening or removal thereof, with or without indicating means, e.g. child-proof closures openable or removable by the combination of plural actions requiring the combination of simultaneous actions, e.g. depressing and turning, lifting and turning, maintaining a part and turning another one
    • B65D50/041—Closures with means for discouraging unauthorised opening or removal thereof, with or without indicating means, e.g. child-proof closures openable or removable by the combination of plural actions requiring the combination of simultaneous actions, e.g. depressing and turning, lifting and turning, maintaining a part and turning another one the closure comprising nested inner and outer caps or an inner cap and an outer coaxial annular member, which can be brought into engagement to enable removal by rotation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D50/00—Closures with means for discouraging unauthorised opening or removal thereof, with or without indicating means, e.g. child-proof closures
    • B65D50/02—Closures with means for discouraging unauthorised opening or removal thereof, with or without indicating means, e.g. child-proof closures openable or removable by the combination of plural actions

Definitions

  • the invention relates to improvements to child-resistant closures for dispensers of liquid medicaments, in particular dispensers of liquid ophthalmic and nasal medicaments, and thereby provides enhanced safety of the dispensers by making the contents of the containers less susceptible to access by children.
  • Child-resistant caps for medicaments have been known in the art for nearly fifty years. These caps generally require two opposed movements acting at the same time to overcome the locking mechanism. For example, one type of cap requires a user to squeeze the cap at specific points, causing a deformation, and then to rotate the cap. If either the squeezing or rotating step is not performed, the cap cannot be opened. Another common method for imparting child-resistance on a cap is to require that the cap be pushed in a downward direction and then turned in order to be removed. Again, it can be seen that the two movements are opposed to one another; it is only through application of this unnatural combination of movements that the cap can be removed. Such a cap is disclosed in U.S. Patent 5,316,161 , and it has the features of the preamble of claim 1.
  • prior art caps often permitted an outer cap to float above and rotate unhindered about an inner cap until the application of a downward force.
  • a major complaint of child-resistant caps has been that they are difficult for the elderly and infirm to remove.
  • the elderly With free-floating caps, the elderly often have a difficult time applying the appropriate amount of downward force necessary to get the appropriate lugs, beams, or fingers to engage.
  • the elderly often have a difficult time maintaining the appropriate downward force throughout the rotational movement.
  • this lack of coordination and partial engagement would result in frustration on the part of the user. Redoubled efforts often resulted in damage to the elements of the cap, through the combination of improper alignment and application of excess force, albeit briefly applied.
  • a cap which reduces potential for damage to component parts through full engagement of lugs, beams, or fingers, (2) prevents over-flexion of lugs, beams, or fingers, (3) modifies the shape of lugs, beams, or fingers, (4) allows the elderly to more easily remove the cap, (5) provides for easier application of the cap by manufacturing processes while at the same time reducing the likelihood of damage to the cap, and (6) minimizes the amount of residual medicament accessible to a child in possession of the removed cap.
  • the present invention provides an improved child-resistant closure for liquid ophthalmic and nasal medicaments, as well as a system for providing child-resistant closure of an existing bottle, and a method of application and removal, providing ease of application during the bottling phase and enhanced child-resistant properties once the apparatus and system have been distributed to an end user.
  • the present invention as defined in claim 1 provides a two-piece, child-resistant closure device for dispensers of liquid medicaments, the closure device comprising:
  • the invention also provides a system for providing child-resistant closure of a bottle of liquid medicaments using the device of the invention, wherein the flexible beam is capable of deformation.
  • the invention also provides a method for removing the child-resistant closure of the invention from an outwardly-threaded bottle of liquid medicaments, the method comprising:
  • the invention also provides a method for affixing the child-resistant closure of the invention to an outwardly-threaded bottle of liquid medicaments, the method comprising:
  • the invention provides for a cap with matching numbers of complementary lugs and beams, with the flexible beams having an angled ridge with an arcuate underside.
  • Additional embodiments of the closure include the requirement that an underside of an upper lug overlap a lower flexible beam by a predetermined distance or range of distances when the lug faces of upper lugs are properly aligned. These embodiments improve upon the reliability of a child-resistant closure by ensuring that it is only engaged when properly aligned, providing ideal frictional contact, and preventing undue stress upon the flexible beams when a downward force has been applied to them.
  • Additional embodiments include modifications to a top portion of the cap, wherein one embodiment provides for a flat top and an alternative embodiment provides for a shaped top, complementary to the shape of a dispenser of liquid medicaments, to minimize the internal volume available for unintentional pooling of excess medicament.
  • An additional embodiment of the invention is a system in which flexion of the flexible beams is limited such that the beam head does not extend below the beam base of an adjacent flexible beam. By limiting such flexion, the beams are not damaged by hyper-flexion.
  • the prior art does not address this issue, and by permitting beams to be unnecessarily hyper-flexed, the resiliency of the beam is decreased, often to the point where no downward force is necessary to engage the lugs of the cap, and the child-resistant nature of the cap has been eliminated.
  • the final embodiments of the invention relate to methods for attaching and removing the closure from a bottle containing liquid medicaments.
  • the steps of applying a downward force and rotating the outer cap are sequential.
  • the steps are simultaneous.
  • the present invention advantageously eliminates the requirement of a constant downward force, such elimination being beneficial for elderly populations or those with arthritis.
  • the final embodiment of the invention relates to the manner in which the invention is affixed to a bottle containing liquid medicaments. In this embodiment, no downward force is necessary.
  • the present method is advantageous in that it does not require a re-tooling of present cap-applying machinery which lack the ability to exert a downward force.
  • overlap shall be understood to mean the horizontal distance measured from the vertical plane of a lug face of a skirt lug to the vertical plane of the nearest beam face of a flexible beam, when the lug faces of shoulder lugs on inner and outer caps are aligned.
  • lug shall be understood to include both male lugs and female lugs.
  • discussion of "lugs” engaging one another shall be understood to include complementary male and female lugs engaging one another, two or more male lugs engaging one another, as well as two or more female lugs engaging one another.
  • discussions of flexible beams engaging lugs shall be understood to include engagement of male or female lugs by a flexible beam.
  • depth when referring to lugs, shall be understood to be a measure of the change in vertical length between a first end and a second of a lug.
  • depth shall be understood to be a measure of the trough created by second end of the lug.
  • depth shall be understood to be a measure of the peak created by the second end of the lug.
  • depth has been selected because in the embodiments shown, shoulder lugs of the outer cap are male and extend in a downward direction, where they mate with female shoulder lugs of the inner cap.
  • depth is not limited to such male-to-female engagements nor to the relative directions depicted in the figures.
  • the closure device of the present invention may be constructed of any one of a number of polyolefins, including but not limited to polypropylene, as well as high- , medium- , and low-density polyethylene. These materials are known for their critical mechanical properties including, but not limited to, their flexural modulus, tensile strength, and elongation, and with the benefit of the present disclosure, one of ordinary skill in the art would understand that other materials exhibiting the same properties could be used in the construction of the cap, and therefore the invention is not limited to embodiments constructed of the materials listed above, but is intended to include all materials, whether presently known or developed in the future, which may exhibit similar structural properties.
  • the child-resistant cap 100 is of a two-part construction, with an outer cap 101 and an inner cap 102.
  • outer cap 101 has a top portion 103 which is adjacent to depending skirt 104.
  • depending skirt 104 contains a gripping surface 105, which may be defined by ridges, dimples, cross-hatching, or any other mechanism or method known to one skilled in the art to increase the friction between the hand of a user and outer cap 104.
  • gripping surface 105 embodied in the form of ridges
  • the invention is not so limited, and it is contemplated that in alternative embodiments, the materials used in the construction of outer cap 101 will provide adequate friction and gripping capabilities for a user, and thus no independent gripping surface 105 may be present.
  • outer cap 101 also has an internal chamber 106 defined by the interior surfaces of top portion 103 and depending skirt 104 .
  • the shape of internal chamber 106 includes shoulder 107 , on which is mounted a quantity of shoulder lugs 108 .
  • Shoulder lugs 108 have a first end 109 and a second end 110 .
  • the depth of shoulder lugs 108 increases from first end 109 to second end 110 .
  • the depth of shoulder lugs 108 may be varied to suit the specific needs of the enclosure, and with the benefit of the present disclosure, one skilled in the art would be enabled to tailor the depth of shoulder lugs appropriately.
  • the depth of shoulder lugs 108 ranges from between 0.381 mm and 1.016 mm (0.015 to 0.040 inches), although the present invention is not limited to this embodiment.
  • Second end 110 has a lug face 111 , oriented perpendicular to the longitude of shoulder lug 108 and distal to first end 109 . Further, the orientation of each lug face 111 is common, providing for a common rotational direction. That is to say, when each lug face 111 is acted upon by another object, the direction of action provides for a consistent rotational action around a central axis.
  • second end 110 also includes a bottom surface extending parallel to the longitude of shoulder lug 108 and providing for a ninety-degree or "right angle" transition from second end 110 to lug face 111 .
  • Internal chamber 106 is further defined by an annular ridge 112 located at a predetermined distance from shoulder 107 .
  • the distance between shoulder 107 and annular ridge 112 is greater than the height of shoulder lugs 108 , and with the benefit of the present disclosure, one skilled in the art would be enabled to tailor the distance between shoulder 107 and annular ridge 112 as required for the size and shape of the bottle and closure in question. In one embodiment, this may range from 14.275 mm and 14,63 mm (0.562 to 0.576 inches), although the present invention is not limited to this embodiment.
  • Annular ridge 112 contains a quantity of skirt lugs 113 .
  • skirt lugs 113 have a first end 114 and a second end 115 , with second end 115 having a lug face 116 .
  • Lug faces 116 are oriented perpendicular to the longitude of skirt lug 113 and distal to first end 114 . Further the orientation of each lug face 116 is common, such that when each lug face 116 is acted upon by another object, a common rotational direction is achieved, providing for rotation about a central axis. However, the orientations of lug faces 116 is opposite that of the orientations of lug faces 111 .
  • Second end 115 also has bottom surface 117 , oriented distal to top portion 103 .
  • Outer cap 101 also includes an assembly retaining bead 130 located within internal chamber 106 at a location distal to both shoulder 107 and annular ridge 112 .
  • assembly retaining bead 130 is located a distance inward from open end 131 of outer cap 101 .
  • assembly retaining bead 130 is located at open end 131 .
  • Outer cap 101 is capable of vertical movement relative to inner cap 102.
  • the vertical downward travel distance of outer cap 101 relative to inner cap 102 is 1.70 mm (0.067 inches), although the present invention is not so limited. Indeed, with the benefit of this disclosure, one skilled in the art would be enabled to determine the appropriate downward travel for bottles of varying sizes, as may be required by product specifications set forth by the manufacturer.
  • inner cap 102 has a top portion 118 , a shoulder 119 , a depending skirt 124 , and an open end 132 .
  • Shoulder 119 is located at the transition point between top portion 118 and depending skirt 124.
  • Figure 3A depicts a quantity of shoulder lugs 120 mounted on shoulder 119 .
  • Shoulder lugs 120 have a first end 121 and a second end 122 .
  • Second end 122 has a lug face 123 located distal to first end 121 and oriented perpendicular to the longitude of shoulder lugs 120.
  • the orientation of lug faces 123 is common, such that when each lug is acted upon by another object, common rotational direction is achieved, providing for rotation about a central axis.
  • the orientation of lug faces 111 is complementary to the orientation of lug faces 123 to provide for engagement of one lug face by the opposing lug face.
  • the depth of shoulder lugs 120 ranges from between 0.381 mm and 1.016 mm (0.015 to 0.040 inches), although the present invention is not limited to this embodiment.
  • depending skirt 124 has a quantity of flexible beams 125 mounted thereon.
  • Flexible beams 125 extend around portions of the perimeter of depending skirt 124 .
  • Each flexible beam 125 consists of a beam base 126 and a beam arm 127 .
  • Beam arm 127 has an angled ridge 128 which terminates in a beam head 129 .
  • Beam base 126 has an upper face 133 and a leading face 134 .
  • Angled ridge 128 has a top side 135 and an underside 136 .
  • Angled ridge 128 is connected to beam base 126 such that top side 135 extends from upper face 133 and underside 136 extends from leading face 134 .
  • Underside 136 extends from leading face 134 in an arcuate or radiused manner.
  • flexion or deformation takes place along angled ridge 128 .
  • the construction of flexible beam 125 is such that it has a resiliency which permits for it to return to its original shape and location when the downward force is no longer applied.
  • underside 136 consists of an arcuate or radiused portion 137 adjacent to a straight portion 138 .
  • underside 136 consists entirely of an arcuate or radiused portion 137 .
  • Beam head 129 has an upper surface 139 and a beam face 140 .
  • the radius of arcuate or radiused portion 137 is 1.651 mm (0.065 inches), although the invention is not so limited. With the benefit of the present specification, one skilled in the art would understand that any radius up to and including a radius of 2.413 mm (0.095 inches) could be utilized. Indeed, as the materials used in the construction of flexible beam 125 vary, different radii may be necessary to provide for maximum resiliency of flexible beam 125 while at the same time ensuring that downward forces exerted upon flexible beam 125 do not result in the deformation of flexible beam 125 in a vector oriented radially to a central axis.
  • Beam faces 140 are located distal to beam base 126 and have an orientation permitting for a common rotational direction about a central axis, such that force imparted on any beam face 140 will result in inner cap 102 rotating in the same direction about a central axis.
  • the orientation of beam faces 140 is complementary to the orientation of lug face 116
  • the common rotational direction of beam faces 140 is complementary to the common rotational direction of lug faces 116 .
  • the quantity of shoulder lugs 108 must be equivalent to the quantity of shoulder lugs 120 . Additionally, the quantity of skirt lugs 113 must be equivalent to the quantity of flexible beams 125 . Equivalent quantities provide for maximum engagement of lugs and complementary lugs and/or beams. Additionally, equivalent quantities of shoulder lugs 108 , shoulder lugs 120 , skirt lugs 113 , and flexible beams 125 provide for maximal engagement of outer cap 101 with inner cap 102 . As such, according to the invention, the quantity of shoulder lugs 108 is equal to the quantity of shoulder lugs 120 and the quantity of skirt lugs 113 is equal to the quantity of flexible beams 125 .
  • the quantities of shoulder lugs 108 , shoulder lugs 120 , skirt lugs 113 , and flexible beams 125 are all equal.
  • Traditional closure mechanisms have permitted unequal numbers of complementary lugs and or beams; such as six lugs designed to be complementary mates to eight fingers. These unequal quantities result in an increased chance of slippage between beams and lugs, and such slippage can result in damage to the flexible beams themselves, including permanent upward or downward deformation of the beams or crushing of the lugs, leading to a decrease in, or even full elimination of, the child-resistant nature of the two-part closure.
  • inner cap also has an internal cavity 141 defined by the internal surfaces of top portion 118 , shoulder 119 , and depending skirt 124 .
  • the internal surface of depending skirt 124 is configured with threads 142 to permit attachment of the cap to a pre-existing bottle with complementary, mated threads on its neck face.
  • top portions 103 and 118 are flat and do not extend above shoulder 107 and 119 respectively.
  • Figures 4A-4B depict cap 100 when it is attached to a pre-existing bottle.
  • Figure 4A shows the outer view of cap 100 when it is attached to a pre-existing bottle.
  • Figure 4B shows a cross-sectional view of cap 100 attached to a bottle, with top portions 103 and 118 extending above and away from shoulder 107 and shoulder 119 respectively.
  • top portions 103 and 118 have a shape which is complementary to the shape of a dispenser nozzle for liquid medicaments. This complementary shape provides for an extra level of safety with regard to access of the medicament by a child.
  • FIG. 5 demonstrates the overlap exhibited by skirt lugs 113 and flexible beam 125 when lug faces 111 and 123 are aligned.
  • the overlap is a predetermined horizontal distance of 0.483 mm (0.019 inches), although the present invention is not so limited, and alternative embodiments include overlaps in a variety of ranges.
  • the range for predetermined horizontal distances of overlap is between 0.406 mm and 0.483 mm (0.016 and 0.022 inches).
  • the range for overlap distance as between 0.330 mm and 0.635 mm (0.013 and 0.025 inches).
  • An additional benefit of the present invention relates to the interaction between shoulder lugs 108 , flexible beams 125 , and assembly retaining bead 130 .
  • flexible beams 125 have a resiliency which allow them to be deformed when a downward force is applied and then return to their original shape and location when the downward force is removed. This resiliency provides an upwards biasing force on shoulder lugs 108 .
  • This upward biasing force is counteracted by assembly retaining bead 130 , in that assembly retaining bead 130 prevents the upward biasing force exerted on shoulder lugs 108 by flexible beams 125 from detaching outer cap 101 from inner cap 102 entirely.
  • skirt lugs 113 will come in contact with flexible beam 125 .
  • Figure 6A shows skirt lug 113 first coming into contact with flexible beam 125 .
  • Figure 6B demonstrates the result when the rotational direction of outer cap 101 continues with skirt lugs 113 riding along angled ridge 128 .
  • outer cap 101 rises and falls vertically with respect to inner cap 102 , in a ratcheting motion when it is rotated in this manner.
  • This position is the optimal deformation of flexible beam 125 , does not travel below the bottom of the adjacent beam base 126 . Further, this downward force deforms or flexes angled ridge 128 such that angled ridge becomes approximately parallel with the adjacent beam base 126 when beam head 129 is at its lowest position.
  • hyper-flexion of flexible beam 125 can be prevented. This is advantageous, because hyper-flexion can result in a loss of resilience of flexible beam 125 .
  • resilience is lost, an active downward force is no longer required to engage lug face 111 of shoulder lug 108 with lug face 123 of shoulder lug 120 .
  • the cap has lost its child-resistant nature.
  • the design of the present invention represents an improvement upon prior art, in that it eliminates hyper-flexion, and thus preserves the child-resistant nature of the cap; while the prior art, lacking such a defined spatial limitation on flexion, permits hyper-flexion and its resultant damage to flexible beam 125 and loss of child-resistant functionality.
  • closure described above is designed to be applied to pre-existing bottles for liquid medicaments. It is understood that these bottles will already have threads provided on their neck finishes.
  • a rotational movement is applied to outer cap 101 in an attaching direction about a central axis and relative to inner cap 102 , the direction most commonly being clockwise, until lug face 116 engages beam face 129 , as shown in Figure 8 .
  • the rotational movement is maintained on outer cap 101 .
  • This force is then transferred to inner cap 102 , permitting the two caps to rotate in concert about a central shared axis.
  • This rotation of inner cap 102 allows threads 142 to engage the threads of the pre-existing bottle. Rotation is maintained until threads 142 have fully engaged the threads of the pre-existing bottle.
  • cap 100 has been affixed to the pre-existing bottle.
  • no additional downward force is required to apply cap 100 to the pre-existing bottle.
  • the engagement of threads 142 with the threads of the pre-existing bottle will impart a downward force on the cap 100 and cause it to travel downwards relative to the pre-existing bottle.
  • this downward force is the mechanical result of the engagement of threads 142 and is not imparted directly by the user. This represents a benefit over the prior art in that present machinery which is only capable of imparting a rotational direction may be used to affix cap 100 to a bottle - there is no re-tooling of the machine necessary.
  • Removal of the cap is effected thusly: a downward force is applied upon outer cap 101 , moving it in a downward direction relative to inner cap 102 . A rotational movement is then applied to outer cap 101 in a removal direction about a central axis relative to inner cap 102 , the direction most commonly being counter-clockwise. Rotation of outer cap 101 is continued until shoulder lugs 108 engage shoulder lugs 120 . Rotation of outer cap 101 continues, and the rotational force is transferred to inner cap 101 due to the engagement of shoulder lugs 108 with shoulder lugs 120 . This continued rotation permits outer cap 101 and inner cap 102 to rotate in concert about a central axis. This rotation of inner cap 102 begins to disengage threads 142 from the threads of the pre-existing bottle.
  • the user may optionally cease applying a downward force on outer cap 101 .
  • This option is available to the user because the flexible beam 125 will impart an upward biasing force on outer cap 101 ; at the same time, the placement of assembly retaining bead 130 will maintain contact between bottom surface 117 of skirt lugs 113 and the angled ridge 128 and beam head 129 of flexible beam 125 . This contact results in friction which continues to transfer the rotational force imparted on outer cap 101 to inner cap 102 .
  • outer cap 101 will result in concerted rotation of inner cap 102 despite the fact that shoulder lugs 108 may no longer be engaging shoulder lugs 120 .
  • the rotational force continues to be applied to outer cap 101 and transferred to inner cap 101 until threads 142 are fully disengaged from the threads of the pre-existing bottle. At this point the cap may be lifted from the pre-existing bottle.
  • the method described above is particularly advantageous for the elderly, as it only requires the downward force to be applied until the torque needed to overcome the static frictional forces between threads 142 and the threads of the bottle has been overcome; it requires the two-directional movement necessary to ensure child-resistance, but by permitting only single-directional movement at later stages of removal, ease of use is increased for those who have decreased coordination or strength due to advanced age and infirmity.
  • first step of applying a downward force and the second step of applying a rotational force may be reversed, such that the rotational force is applied first and the downward force is applied second.
  • first two steps of applying a downward force and applying a rotational force are combined into a single step wherein the downward and rotational forces are applied simultaneously.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Closures For Containers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
EP13816761.4A 2012-07-13 2013-07-12 Improved child-resistant cap for liquid medicaments Active EP2872415B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261671194P 2012-07-13 2012-07-13
PCT/US2013/050220 WO2014011965A1 (en) 2012-07-13 2013-07-12 Improved child-resistant cap for liquid medicaments

Publications (3)

Publication Number Publication Date
EP2872415A1 EP2872415A1 (en) 2015-05-20
EP2872415A4 EP2872415A4 (en) 2016-02-24
EP2872415B1 true EP2872415B1 (en) 2019-09-04

Family

ID=49913069

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13816761.4A Active EP2872415B1 (en) 2012-07-13 2013-07-12 Improved child-resistant cap for liquid medicaments

Country Status (7)

Country Link
US (1) US20140014611A1 (es)
EP (1) EP2872415B1 (es)
JP (1) JP6322352B2 (es)
CN (1) CN104603017B (es)
CA (1) CA2879081C (es)
MX (1) MX367823B (es)
WO (1) WO2014011965A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2677150T3 (es) 2012-11-15 2018-07-30 Amcor Group Gmbh Conjunto de cierre de punta a prueba niños con muelle de dedo
US10370161B2 (en) * 2012-11-15 2019-08-06 Amcor Rigid Plastics Usa, Llc Child resistant tip closure assembly with diaphragm
US9580213B2 (en) * 2014-12-15 2017-02-28 Johnson & Johnson Consumer Inc. Child resistant closure for a container
EP3093074B1 (de) * 2015-05-13 2019-12-04 Aptar Radolfzell GmbH Austragkopf für einen spender zum austrag einer flüssigkeit sowie spender mit einem solchen austragkopf und befestigungsabschnitt für einen solchen austragkopf
USD784812S1 (en) * 2015-08-04 2017-04-25 Ignite Usa, Llc Cap for a bottle
USD796325S1 (en) * 2015-08-04 2017-09-05 Ignite Usa, Llc Cap for a bottle
USD841471S1 (en) 2017-02-24 2019-02-26 S. C. Johnson & Son, Inc. Bottle
USD845135S1 (en) 2017-02-24 2019-04-09 S. C. Johnson & Son, Inc. Bottle neck with cap
JP7021861B2 (ja) * 2017-03-23 2022-02-17 小林製薬株式会社 薬液供給器具
JP7021859B2 (ja) * 2017-03-23 2022-02-17 小林製薬株式会社 薬液供給器具
JP7021860B2 (ja) * 2017-03-23 2022-02-17 小林製薬株式会社 薬液供給器具
JP6883324B2 (ja) * 2017-06-27 2021-06-09 キタノ製作株式会社 安全キャップ
US20190161254A1 (en) * 2017-11-29 2019-05-30 Cory J. Wilson Child-resistant cap
CN113329947A (zh) * 2018-11-27 2021-08-31 里克有限责任公司 具有防拆封、防燃烧和/或防脱扭特征的轻质、防儿童开启封闭件
MA55452A (fr) 2019-03-29 2022-02-09 Lilly Co Eli Systèmes et procédés d'administration de médicament
MX2022007236A (es) * 2019-12-11 2022-09-21 Berry Global Inc Cierre con evidencia de manipulacion.
CN212173124U (zh) * 2020-09-30 2020-12-18 东莞市鑫宇制罐有限公司 一种具有安全锁功能的包装盒
CN114275348A (zh) * 2021-12-23 2022-04-05 安徽悦博生物制药有限公司 一种防误开药瓶

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3797688A (en) * 1972-06-14 1974-03-19 Federal Tool & Plastics Safety cap unit
DE7520607U (de) * 1975-06-28 1975-10-23 Hofmann Metall Kunststoff Kindergesicherter Schraubverschluss fuer Behaelter
JPS52165857U (es) * 1976-06-09 1977-12-15
US4319690A (en) * 1979-12-13 1982-03-16 International Tools (1973) Limited Child-resistant closure and container assembly including improved outer cap
FR2532625A2 (fr) * 1982-09-07 1984-03-09 Perinet Philippe Perfectionnements aux recipients a fermeture de protection vis-a-vis des enfants
US5316161A (en) * 1993-04-20 1994-05-31 Comar, Inc. Child resistant closure
GB9312275D0 (en) * 1993-06-15 1993-07-28 Wellcome Found Cap for a container
JPH08268452A (ja) * 1995-02-02 1996-10-15 Canyon Corp チャイルドプル−フ機構付ボトルキャップ
IT1304829B1 (it) * 1998-11-19 2001-04-05 Lameplast Srl Flacone con tappo di sicurezza, particolarmente per prodottifarmaceutici.
US8235616B2 (en) * 2009-11-12 2012-08-07 Enrico Raccah Safety closure for nail polish bottle

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
None *

Also Published As

Publication number Publication date
JP2015527268A (ja) 2015-09-17
MX2015000555A (es) 2015-05-08
CA2879081C (en) 2020-08-04
EP2872415A4 (en) 2016-02-24
CN104603017B (zh) 2016-11-02
MX367823B (es) 2019-09-09
CN104603017A (zh) 2015-05-06
WO2014011965A1 (en) 2014-01-16
EP2872415A1 (en) 2015-05-20
JP6322352B2 (ja) 2018-05-09
CA2879081A1 (en) 2014-01-16
US20140014611A1 (en) 2014-01-16

Similar Documents

Publication Publication Date Title
EP2872415B1 (en) Improved child-resistant cap for liquid medicaments
US10118739B2 (en) Child resistant closure for a container
AU737790B2 (en) Child resistant package
US4020965A (en) Child resistant closure
EP2872414B1 (en) Upwardly biasing child-resistant closure for liquid medicaments
US20050269373A1 (en) Cover for dispensing closure with pressure actuated valve
US20110006030A1 (en) Child Resistant Closure with a Stacking Position
US6536586B2 (en) Combination vessel of a cap type sealing tool having tamper function and a bottle portion
US20190185249A1 (en) Rotable cap system for dispensing one or two tablets or capsules from a pharmacy vial
EP3077300B1 (en) Closure cap
EP2116478B1 (en) A packaging comprising a closure allowing insertion of a tool
US11377272B2 (en) Device for closing a container by screwing, secured by a retractable lug
US20040040928A1 (en) Retained satellite ring cap and bottle assembly
JP2007091293A (ja) 中栓付き容器
CN112429397A (zh) 一种可防儿童误开启的药瓶
KR200423175Y1 (ko) A형식 안전마개
WO1995001920A1 (en) Pharmaceutical container
CN111319867A (zh) 一种包装容器

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20150210

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAX Request for extension of the european patent (deleted)
RA4 Supplementary search report drawn up and despatched (corrected)

Effective date: 20160125

RIC1 Information provided on ipc code assigned before grant

Ipc: B65D 50/04 20060101AFI20160119BHEP

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: COMAR, LLC

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

17Q First examination report despatched

Effective date: 20170327

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: GRANT OF PATENT IS INTENDED

INTG Intention to grant announced

Effective date: 20190308

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE PATENT HAS BEEN GRANTED

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 1175018

Country of ref document: AT

Kind code of ref document: T

Effective date: 20190915

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602013060119

Country of ref document: DE

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: NL

Ref legal event code: MP

Effective date: 20190904

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG4D

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191204

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191204

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191205

Ref country code: AL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

Ref country code: RS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

REG Reference to a national code

Ref country code: AT

Ref legal event code: MK05

Ref document number: 1175018

Country of ref document: AT

Kind code of ref document: T

Effective date: 20190904

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200106

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200224

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

Ref country code: SM

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 602013060119

Country of ref document: DE

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

PG2D Information on lapse in contracting state deleted

Ref country code: IS

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200105

26N No opposition filed

Effective date: 20200605

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200712

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200731

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200731

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

Ref country code: MT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190904

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IT

Payment date: 20230720

Year of fee payment: 11

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20240718

Year of fee payment: 12

Ref country code: IE

Payment date: 20240719

Year of fee payment: 12

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20240719

Year of fee payment: 12

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: BE

Payment date: 20240719

Year of fee payment: 12

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20240722

Year of fee payment: 12