EP2859123A4 - Verfahren zur sequenzbestimmung mittels sequenztags - Google Patents

Verfahren zur sequenzbestimmung mittels sequenztags

Info

Publication number
EP2859123A4
EP2859123A4 EP13804085.2A EP13804085A EP2859123A4 EP 2859123 A4 EP2859123 A4 EP 2859123A4 EP 13804085 A EP13804085 A EP 13804085A EP 2859123 A4 EP2859123 A4 EP 2859123A4
Authority
EP
European Patent Office
Prior art keywords
sequence
determination
tags
sequence tags
sequence determination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP13804085.2A
Other languages
English (en)
French (fr)
Other versions
EP2859123A2 (de
Inventor
Malek Faham
Martin Moorhead
Thomas Willis
Jianbiao Zheng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adaptive Biotechnologies Corp
Original Assignee
Sequenta Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/835,093 external-priority patent/US9506119B2/en
Application filed by Sequenta Inc filed Critical Sequenta Inc
Publication of EP2859123A2 publication Critical patent/EP2859123A2/de
Publication of EP2859123A4 publication Critical patent/EP2859123A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
EP13804085.2A 2012-06-11 2013-06-11 Verfahren zur sequenzbestimmung mittels sequenztags Withdrawn EP2859123A4 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201261658317P 2012-06-11 2012-06-11
US201261738277P 2012-12-17 2012-12-17
US201361776647P 2013-03-11 2013-03-11
US13/835,093 US9506119B2 (en) 2008-11-07 2013-03-15 Method of sequence determination using sequence tags
US201361829054P 2013-05-30 2013-05-30
PCT/US2013/045276 WO2013188471A2 (en) 2012-06-11 2013-06-11 Method of sequence determination using sequence tags

Publications (2)

Publication Number Publication Date
EP2859123A2 EP2859123A2 (de) 2015-04-15
EP2859123A4 true EP2859123A4 (de) 2015-12-16

Family

ID=49758873

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13804085.2A Withdrawn EP2859123A4 (de) 2012-06-11 2013-06-11 Verfahren zur sequenzbestimmung mittels sequenztags

Country Status (7)

Country Link
EP (1) EP2859123A4 (de)
JP (1) JP2015519081A (de)
CN (1) CN104520443A (de)
AU (1) AU2013274366A1 (de)
CA (1) CA2875542A1 (de)
SG (1) SG11201407888RA (de)
WO (1) WO2013188471A2 (de)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8748103B2 (en) 2008-11-07 2014-06-10 Sequenta, Inc. Monitoring health and disease status using clonotype profiles
US9394567B2 (en) 2008-11-07 2016-07-19 Adaptive Biotechnologies Corporation Detection and quantification of sample contamination in immune repertoire analysis
US9506119B2 (en) 2008-11-07 2016-11-29 Adaptive Biotechnologies Corp. Method of sequence determination using sequence tags
GB2483810B (en) 2008-11-07 2012-09-05 Sequenta Inc Methods for correlating clonotypes with diseases in a population
US8628927B2 (en) 2008-11-07 2014-01-14 Sequenta, Inc. Monitoring health and disease status using clonotype profiles
US9528160B2 (en) 2008-11-07 2016-12-27 Adaptive Biotechnolgies Corp. Rare clonotypes and uses thereof
US9365901B2 (en) 2008-11-07 2016-06-14 Adaptive Biotechnologies Corp. Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia
PT2387627E (pt) 2009-01-15 2016-06-03 Adaptive Biotechnologies Corp Determinação do perfil de imunidade adaptativa e métodos de geração de anticorpos monoclonais
WO2010151416A1 (en) 2009-06-25 2010-12-29 Fred Hutchinson Cancer Research Center Method of measuring adaptive immunity
US9043160B1 (en) 2009-11-09 2015-05-26 Sequenta, Inc. Method of determining clonotypes and clonotype profiles
US10385475B2 (en) 2011-09-12 2019-08-20 Adaptive Biotechnologies Corp. Random array sequencing of low-complexity libraries
AU2012325791B2 (en) 2011-10-21 2018-04-05 Adaptive Biotechnologies Corporation Quantification of adaptive immune cell genomes in a complex mixture of cells
EP2788509B1 (de) 2011-12-09 2018-07-11 Adaptive Biotechnologies Corporation Diagnose von lymphoid-malignität und nachweis minimaler resterkrankungen
US9499865B2 (en) 2011-12-13 2016-11-22 Adaptive Biotechnologies Corp. Detection and measurement of tissue-infiltrating lymphocytes
EP3372694A1 (de) 2012-03-05 2018-09-12 Adaptive Biotechnologies Corporation Festlegung von gepaarten immunrezeptorketten aus frequenzabgestimmten untereinheiten
SG10201507700VA (en) 2012-05-08 2015-10-29 Adaptive Biotechnologies Corp Compositions and method for measuring and calibrating amplification bias in multiplexed pcr reactions
EP2882870A4 (de) * 2012-08-10 2016-03-16 Sequenta Inc Hochempfindlicher nachweis von mutationen mittels sequenz-tags
US20160040229A1 (en) 2013-08-16 2016-02-11 Guardant Health, Inc. Systems and methods to detect rare mutations and copy number variation
IL305303A (en) 2012-09-04 2023-10-01 Guardant Health Inc Systems and methods for detecting rare mutations and changes in number of copies
US11913065B2 (en) 2012-09-04 2024-02-27 Guardent Health, Inc. Systems and methods to detect rare mutations and copy number variation
US10876152B2 (en) 2012-09-04 2020-12-29 Guardant Health, Inc. Systems and methods to detect rare mutations and copy number variation
CN105189779B (zh) 2012-10-01 2018-05-11 适应生物技术公司 通过适应性免疫受体多样性和克隆性表征进行的免疫能力评估
WO2015160439A2 (en) 2014-04-17 2015-10-22 Adaptive Biotechnologies Corporation Quantification of adaptive immune cell genomes in a complex mixture of cells
US9708657B2 (en) 2013-07-01 2017-07-18 Adaptive Biotechnologies Corp. Method for generating clonotype profiles using sequence tags
CN106062214B (zh) 2013-12-28 2020-06-09 夸登特健康公司 用于检测遗传变异的方法和系统
DE102014200446B3 (de) * 2014-01-13 2015-01-08 Technische Universität Dresden Verfahren zur Dekonvolution Nukleinsäure enthaltender Substanzgemische
EP3114240B1 (de) 2014-03-05 2019-07-24 Adaptive Biotechnologies Corporation Verfahren unter verwendung von randomerhaltigen synthetischen molekülen
US10066265B2 (en) 2014-04-01 2018-09-04 Adaptive Biotechnologies Corp. Determining antigen-specific t-cells
WO2016069886A1 (en) 2014-10-29 2016-05-06 Adaptive Biotechnologies Corporation Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples
EP3018214B1 (de) 2014-11-05 2017-12-13 Fundacion de Investigacion Hospital 12 de Octubre Verfahren zur Quantifizierung des Niveaus minimaler Resterkrankung bei einer Person
US10246701B2 (en) 2014-11-14 2019-04-02 Adaptive Biotechnologies Corp. Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture
EP3498866A1 (de) 2014-11-25 2019-06-19 Adaptive Biotechnologies Corp. Charakterisierung von adaptiver immunreaktion auf impfungen oder infektionen unter verwendung von immunrepertoiresequenzierung
AU2016222788B2 (en) 2015-02-24 2022-03-31 Adaptive Biotechnologies Corp. Methods for diagnosing infectious disease and determining HLA status using immune repertoire sequencing
AU2016242967B2 (en) 2015-04-01 2021-07-01 Adaptive Biotechnologies Corp. Method of identifying human compatible T cell receptors specific for an antigenic target
CN105095687B (zh) * 2015-06-26 2018-10-26 南方科技大学 一种免疫组库数据分析方法及终端
EP3325646B1 (de) 2015-07-22 2020-08-19 F.Hoffmann-La Roche Ag Identifizierung von antigen-epitopen und immunsequenzen zur erkennung der antigene
US10539564B2 (en) 2015-07-22 2020-01-21 Roche Sequencing Solutions, Inc. Identification of antigen epitopes and immune sequences recognizing the antigens
EP3387108B1 (de) * 2015-12-08 2022-05-25 Quantapore, Inc. Verfahren zur verlagerung von nukleinsäuren durch nanoporen
CN108603228B (zh) 2015-12-17 2023-09-01 夸登特健康公司 通过分析无细胞dna确定肿瘤基因拷贝数的方法
US10428325B1 (en) 2016-09-21 2019-10-01 Adaptive Biotechnologies Corporation Identification of antigen-specific B cell receptors
CN107955831A (zh) * 2016-10-13 2018-04-24 深圳华大基因研究院 用于淋巴细胞定量检测的标记物和淋巴细胞定量检测方法
CN106755410B (zh) * 2016-12-23 2019-12-06 孙涛 一种基于高通量测序同时检测t细胞和b细胞免疫组库的方法
EP3625714B1 (de) * 2017-05-16 2021-03-17 Life Technologies Corporation Verfahren zur kompression von molekularen markierten nukleinsäuresequenzdaten
CN110678559B (zh) * 2017-08-31 2023-09-15 深圳华大智造科技股份有限公司 一种核酸探针以及一种核酸测序方法
EP4212631A1 (de) 2017-09-01 2023-07-19 Life Technologies Corporation Zusammensetzungen und verfahren zur sequenzierung des immunrepertoires
WO2019080725A1 (zh) * 2017-10-25 2019-05-02 深圳华大生命科学研究院 一种核酸测序方法以及一种核酸测序试剂盒
US11254980B1 (en) 2017-11-29 2022-02-22 Adaptive Biotechnologies Corporation Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements
CN111172258B (zh) * 2020-02-24 2023-06-16 国家海洋环境监测中心 基于宏条形码技术的海洋浮游动物多样性的评价方法
JP2023519919A (ja) * 2020-03-24 2023-05-15 オングストローム バイオ，インコーポレイテッド 病原体を検出するためのアッセイ
US20230041268A1 (en) 2021-03-24 2023-02-09 Genentech, Inc. Efficient tcr gene editing in t lymphocytes
CN113355403A (zh) * 2021-05-12 2021-09-07 邢迎春 一种利用环境dna技术检测鱼类物种多样性的方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846719A (en) * 1994-10-13 1998-12-08 Lynx Therapeutics, Inc. Oligonucleotide tags for sorting and identification
WO2009017678A2 (en) * 2007-07-26 2009-02-05 Pacific Biosciences Of California, Inc. Molecular redundant sequencing
WO2012055929A1 (en) * 2010-10-26 2012-05-03 Illumina, Inc. Sequencing methods
WO2013130512A2 (en) * 2012-02-27 2013-09-06 The University Of North Carolina At Chapel Hill Methods and uses for molecular tags

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2483810B (en) * 2008-11-07 2012-09-05 Sequenta Inc Methods for correlating clonotypes with diseases in a population
US8748103B2 (en) * 2008-11-07 2014-06-10 Sequenta, Inc. Monitoring health and disease status using clonotype profiles
US8691510B2 (en) * 2008-11-07 2014-04-08 Sequenta, Inc. Sequence analysis of complex amplicons

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846719A (en) * 1994-10-13 1998-12-08 Lynx Therapeutics, Inc. Oligonucleotide tags for sorting and identification
WO2009017678A2 (en) * 2007-07-26 2009-02-05 Pacific Biosciences Of California, Inc. Molecular redundant sequencing
WO2012055929A1 (en) * 2010-10-26 2012-05-03 Illumina, Inc. Sequencing methods
WO2013130512A2 (en) * 2012-02-27 2013-09-06 The University Of North Carolina At Chapel Hill Methods and uses for molecular tags

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
C. B. JABARA ET AL: "Accurate sampling and deep sequencing of the HIV-1 protease gene using a Primer ID", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 108, no. 50, 30 November 2011 (2011-11-30), pages 20166 - 20171, XP055201609, ISSN: 0027-8424, DOI: 10.1073/pnas.1110064108 *
MEGAN MANION ET AL: "Reducing Error in Next Generation Sequencing Data with NextGENe Software's Condensation Tool", March 2009 (2009-03-01), pages 1 - 3, XP055226038, Retrieved from the Internet <URL:http://www.softgenetics.com/PDF/ReducingError_NextGenerationSequencing_AppNote.pdf> [retrieved on 20151105] *
MILLER JASON R ET AL: "Assembly algorithms for next-generation sequencing data", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 95, no. 6, 6 March 2010 (2010-03-06), pages 315 - 327, XP009165741, ISSN: 0888-7543 *

Also Published As

Publication number Publication date
WO2013188471A2 (en) 2013-12-19
JP2015519081A (ja) 2015-07-09
WO2013188471A3 (en) 2014-04-03
EP2859123A2 (de) 2015-04-15
AU2013274366A1 (en) 2015-01-22
CA2875542A1 (en) 2013-12-19
SG11201407888RA (en) 2014-12-30
CN104520443A (zh) 2015-04-15

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