EP2732877B1 - Piston stroke pipette with exchangeable displacer unit - Google Patents
Piston stroke pipette with exchangeable displacer unit Download PDFInfo
- Publication number
- EP2732877B1 EP2732877B1 EP13005269.9A EP13005269A EP2732877B1 EP 2732877 B1 EP2732877 B1 EP 2732877B1 EP 13005269 A EP13005269 A EP 13005269A EP 2732877 B1 EP2732877 B1 EP 2732877B1
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- EP
- European Patent Office
- Prior art keywords
- drive unit
- magnetic
- unit
- drive
- magnetic connection
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- 230000005291 magnetic effect Effects 0.000 claims description 136
- 230000033001 locomotion Effects 0.000 claims description 25
- 238000006073 displacement reaction Methods 0.000 claims description 23
- 230000008878 coupling Effects 0.000 claims description 12
- 238000010168 coupling process Methods 0.000 claims description 12
- 238000005859 coupling reaction Methods 0.000 claims description 12
- 238000000926 separation method Methods 0.000 claims description 11
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical group [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 10
- 239000007788 liquid Substances 0.000 description 9
- 238000010276 construction Methods 0.000 description 6
- 230000006378 damage Effects 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 229910052742 iron Inorganic materials 0.000 description 3
- 230000001133 acceleration Effects 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 210000003811 finger Anatomy 0.000 description 2
- 239000000696 magnetic material Substances 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 210000003813 thumb Anatomy 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000005294 ferromagnetic effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
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- 230000000284 resting effect Effects 0.000 description 1
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Images
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
- B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0275—Interchangeable or disposable dispensing tips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/028—Modular arrangements
Definitions
- the invention relates to a piston stroke pipette with a drive unit and a displacer unit mounted on the drive unit with the features of the preamble of claim 1.
- Such reciprocating pipettes are used in practice for transferring liquid using pipette tips.
- Such Kolbenhubpipetten have as so-called multi-channel pipettes eight or twelve piston-cylinder units and require correspondingly high actuation forces. The same occurs with single-channel large-volume pipettes.
- the detachable mechanical connections or coupling devices of the pipettes transmit these forces, so that their magnetic force must be high.
- the magnetic force can be overcome manually only with difficulty. The separation is jerky, is uncomfortable and may lead to injury or damage.
- the drive unit due to the magnetic force can also cause injury between the two components.
- Another Kolbenhubpipette is from the WO-A-02/29419 with a detachable by means of a magnetic coupling device dosing known.
- This device has a Cartesian axis system for moving a dosing head.
- One or more hollow needles can be added to the liquid and discharged, are arranged on the dosing.
- the coupling device is located between the dosing head and a holding device arranged on the axle system.
- the dosing head and the holding device have a permanent magnet.
- the holding device to an electromagnet, which requires its own power supply.
- an electromagnet increases, and it even requires several, the weight of Kolbenhubpipette considerably.
- the invention is based on the problem of designing the known Kolbenhubpipette with a designed as a magnetic connection releasable mechanical connection between the drive unit and the displacer unit and further that it is ergonomically operable and effective to handle.
- the invention is based on the idea of overcoming or adequately mitigating the magnetic force of at least the detachable mechanical connection designed as a magnetic connection between the receiving section of the drive unit and the fastening section of the displacer unit with an additional mechanical means.
- the operator can thus easily and safely remove the displacer unit from the drive unit.
- the displacer unit can in the opposite direction by means of the mechanical means for Disconnect the magnetic connection again gently and controlled to be coupled to the drive unit.
- the magnetic connection of the piston stroke pipette according to the invention is designed more practical than in the prior art.
- the operator of the piston-operated pipette is safe to handle when separating the drive unit and the displacer unit. This can be done without much manual effort. A risk of injury due to the jerky release of the magnetic connection is excluded.
- the assembly of the drive unit and the displacer unit is easily and safely possible.
- the mechanical means is designed according to one of the following three alternatives.
- the mechanical means comprises an axially profiled cam disc and a cam guide congruent with the cam disc.
- the mechanical means for separating the magnetic connection between the receiving portion and the attachment portion may be basically actuated by a motor actuator. An operator then actuates only one trigger element, for example a button, and the actuator drives the mechanical means for disconnecting the magnetic connection and disconnects this magnetic connection.
- the mechanical means for separating the magnetic connection is a manually, that is manually operable means. This makes the construction of the piston stroke pipette simple and inexpensive.
- Magneticly particularly robust and expedient is a construction in which the magnetic connection is simply separable by pushing away the displacer unit from the drive unit or vice versa.
- the magnetic connection can also be separated only by itself so that the components of the magnetic connection are pressed apart and thereby the holding force of the magnetic connection is weakened so that the displacer unit can then be easily removed by the drive unit.
- the releasable mechanical connection between the actuating drive and the piston drive need not be designed as a magnetic connection. In the prior art, it is designed as a magnetic connection. But it can also be designed as a latching connection o. The like. In the case of a design as a magnetic connection, it is particularly preferable for it to be separable likewise by actuation of the manually operable means.
- Fig. 1 shows a Kolbenhubpipette 1 for transferring liquid with a drive unit 2, a displacer unit 3 and a coupling device connecting both units 4.
- a plurality of shafts 5 are arranged for attaching pipette tips, not shown.
- the aspiration and ejection of the liquid takes place via pistons 9 'and cylinders 9 "located in the displacer unit 3, which change the volume of air in the pipette tips and above Fig. 3 one sees this by way of example in the left-opened section of the displacer unit 3.
- Fig. 1 is a multi-channel piston stroke pipette 1 shown with multiple shafts 5, however, the teaching can also be applied to a piston stroke pipette 1 with a single-channel displacer unit 3. Likewise, the teaching can be applied to direct displacement. So it is any form of Kolbenhubpipetten suitable according to DIN EN ISO 8655-2.
- the Fig. 2 shows the drive unit 2, partially the displacer unit 3 and the coupling device formed therebetween 4.
- drive unit 2 In the enclosed by a housing 6 drive unit 2 is a Hubaktor 7 with an actuating drive 8, which drives a piston drive 9 in the displacer unit 3 in the direction of a common axis 10 ,
- the Hubaktor 7 shown is a positioning drive with electric motor and battery. Other motion transmissions, drives or power sources are possible.
- all necessary operating, display and controls for operation and adjustment are normally arranged.
- the piston drive 9 is in turn with the in Fig. 2 not shown piston (but see Fig. 3 , Piston 9 ') operatively connected. Between the actuating drive 8 and the piston drive 9 there is a first mechanical connection 11.
- This first mechanical connection 11 is detachable. In the illustrated and preferred embodiment, it is designed as a magnetic connection 11. However, this first mechanical connection can also be designed as a purely mechanical connection, ie frictional and / or positive (latching connection). It is important that this mechanical connection 11 securely couples the piston drive 9 with the actuating drive 8 when the displacer unit 3 is coupled to the drive unit 2, so that the movement of the actuation drive 8 is reliably and precisely transmitted to the piston drive 9. However, the first mechanical connection 11 must also be detachable, because when separating the displacer unit 3 from the drive unit 2, the piston drive 9 has to be decoupled from the actuation drive 8.
- the embodiment of the first mechanical connection shown here as a magnetic connection 11 consists of magnetic means, namely a permanent magnet 12 on the actuating drive 8 and a soft iron core 13 on the piston drive 9.
- the magnetic connection 11 shown can also be realized by two permanent magnets or possibly also by an electrically disconnectable magnet become.
- This drive movement transmitting connection 11 is sufficiently dimensioned, but still separable at normal excessive movement of force introduction. The separability can be made possible depending on the type of connection by loosening and / or removing the or further necessary components.
- the upper end of the displacer unit 3 has a mounting portion 14, 17 with a guide sleeve 14 which is inserted coaxially to the axis 10 in a receiving portion 15 of the drive unit 2.
- the actuating drive 8 Inside the guide sleeve 14, the actuating drive 8, the piston drive 9 and the first mechanical connection 11 are here in the form of the magnetic connection 11.
- a second mechanical connection 16 of the coupling device 4 in the form of a magnetic connection 16 is comprised between the receiving section 15 of the drive unit 2 and the actuating section 14 of the displacer unit 3, that is to say the guide sleeve 14.
- Embodiment consists of the magnetic connection 16 of magnetic means, namely a plurality of individual permanent magnets 16 'which are fixed in the housing 6, and a disc 17 made of soft iron or other magnetic material, which is fixed to the guide sleeve 14.
- the magnetic connection 16 is dimensioned so that the thrust generated by the actuator 8 under any circumstances triggers an unwanted separation during the liquid ejection.
- the pipetted dispensed volume must always be correct.
- the holding force of the magnetic connection 16 is correspondingly high. In the preferred embodiment shown and in FIG Fig. 4 it can therefore be seen that three permanent magnets 16 'are provided.
- Fig. 2 and the step-by-step illustrations of Fig. 2a to 2f now show a mechanical, manually operable means 18 which is provided for separating the magnetic connection 16 between the receiving portion 15 and the mounting portion 14.
- the magnetic connection 16 is separable.
- the displacer unit 3 can be released from the drive unit 2 with comparatively little effort and in any case in a controlled manner.
- this is either completely ineffective or at least weakened in its holding force so far that then the displacer unit 3 with little effort and controlled by the drive unit 2 can be removed.
- the magnetic connection 16 by pushing away the displacer unit 3 of the drive unit 2 separable.
- the separating movement is an axial movement along the common longitudinal axis 10.
- the first releasable mechanical connection 11 between the actuating drive 8 and the piston drive 9 is designed as a magnetic connection 11. This can be done by pressing the manual operable means 18 for separating the magnetic connection 16 are also separated. In detail, this will be explained below.
- the manually operable means 18 for separating a lever 19 which is mounted with a pivot point 20 on the drive unit 2 and acts on manual operation on the displacer unit 3, thereby separating the magnetic connection 16.
- Fig. 8 another construction is shown, in which the lever 19 is mounted with a pivot point 20 on the displacer unit 3, acts on the drive unit 2 with manual actuation, thus separating the magnetic connection 16.
- the drive unit 2 is separated from the displacer unit 3. The result, of course, has the same effect, it is just another constructive solution.
- Fig. 2 illustrated preferred embodiment is further characterized in that the lever 19 has a manually operable button 21 which is operable in the illustrated embodiment in a direction which is transverse to the direction of the separation movement of drive unit 2 and displacer unit 3.
- the button 21 of the here mounted on the drive unit 2 lever 19 is disposed above the pivot point 20 of the lever 19. This positioning of the probe 21 makes it possible to actuate the button 21 with the thumb and at the same time to hold the displacer unit 3 loosely with one or two fingers of the hand, so that it can not easily fall off upon release from the drive unit 2.
- Fig. 8 shows a reverse arrangement of the lever 19.
- the lever 19 with its button 21 is not up, but down.
- the lever 19 is arranged on the displacer unit 3 in this embodiment.
- such an arrangement of the lever 19 with downwardly facing button 21 can also be convenient in terms of handling for a arranged on the drive unit 2 lever 19.
- Fig. 2 illustrated embodiment is further characterized in that the lever 19 for separating the magnetic connection 16 has a lever arm 22.
- a supported on the housing 6 of the drive unit 2 return spring 23 is provided which presses the longer lever arm with the button 21 and thus the lever 19 in its rest position, in which the magnetic connection 11 is not separated. This serves a defined position of the lever 19 on the Kolbenhubpipette. 1
- FIG. 2 illustrated embodiment also shows that here the distance of the probe 21 from the pivot point 20 of the lever 19 is substantially longer than the lever arm 22. In the illustrated and preferred embodiment, this distance is about six times as long as the lever arm 22 of the lever 19. This results in a appropriate distance reduction and power transmission.
- the button 21 is moved over a relatively large path, but this happens with very little force.
- the small separating lever arm 22 is moved over a comparatively short stroke, but with a high force, which is turned off on the holding force of the magnetic connection 16.
- the stroke of the lever arm 22 during manual actuation for the purpose of separation is about 0.3 mm to 2.0 mm, preferably about 1.0 mm. This applies to the embodiment shown here and so far preferred.
- Fig. 2a to 2f show a preferred Kolbenhubpipette 1 in movement positions of different processes.
- Fig. 2a is the typical resting, starting and dispensing position of the pipette.
- the actuator 8 and the piston drive 9 and not illustrated piston in the lower quarter of the stroke range.
- the actuator 8 is extended to about three quarters of its maximum stroke.
- the pipette tip, not shown, is immersed in the liquid.
- the stroke A is limited in a manual Kolbenhubpipette1 by stops not shown or defined in an electromotive Kolbenhubpipette1 example, by the preselected revolutions of the drive.
- the maximum stroke A shows Fig. 2b ,
- Fig. 2a moves, which can be limited as well.
- the piston can continue for a short time, as in Fig. 2c shown to be moved (overtravel B).
- displacer unit 3 is to be exchanged or another, for example one with a larger piston or one with a different number of channels, is used, then this is possible because of the coupling device 4.
- the actuating drive 8 and the piston drive 9 are connected by the first magnetic connection 11 and are, as Fig. 2d shows, separated.
- the actuating drive 8 is moved beyond the maximum stroke A of the piston drive 9 and thereby the permanent magnet 12 is released from the soft iron core 13. You can see this in the transition from Fig. 5c of FIG. 5d ,
- the piston drive 9 is held in its upward movement by a stop.
- the actuator 8 is driven by the Hubaktors 7 a little further up.
- the permanent magnet 12 separates from the soft iron core 13.
- the first mechanical connection in the form of the magnetic connection 11 is disconnected. It can be seen from this description that in this case the mechanical means 18 for separating for the first mechanical connection 11 has no function.
- Fig. 2e shows how the lever 19 is pressed on its button 21 against the spring force of the return spring 23 in the direction of arrow C.
- the arm with the button 21 is significantly longer than the shorter lever arm 22.
- the lever arm 22 With the lever arm 22, the high holding force of the magnetic connection 16 can be easily overcome manually.
- the short stroke of the short lever arm 22 causes a slight acceleration of the separated displacer unit 3rd
- the stroke D is in Fig. 2e so short that with pressed button 21, the magnetic force between the magnetic means of the magnetic connection 16 is greater than the weight of the displacer unit 3.
- this design causes only a slight acceleration of the falling displacer unit 3 when the key 21 is actuated or only a short movement of the displacer unit 3 downwardly takes place analogously to the path of the short lever arm 22.
- the stroke D of the short lever arm 22 is about 1 mm.
- the advantageous in handling effect is achieved here by a limited to 0.3 to 2 mm long stroke D of the short lever arm 22.
- the removal of the displacer unit 3 with an actuator, for example by holding the displacer unit 3 in a shelf and lifting the drive unit 2.
- the switching of detents in the locking and releasing position can be realized by means of an actuator.
- the switching operation can be initiated.
- Fig. 2f is the withdrawn from the drive unit 2 displacer unit 3 is shown and their joining movements are indicated by the vertical arrow E.
- the guide sleeve 14 is pushed forward in the receiving portion 15 of the drive unit 2 until the magnetic connection 16 again couples. If necessary, the first magnetic connection 11 also comes together again or it is engaged by the extension of the actuating drive 8.
- Fig. 2f the unactuated lever 19 is shown in its rest position occupied by the return spring 23.
- the short lever arm 22 lies behind the plane which defines the underside of the permanent magnets 16 '( Fig. 2 ).
- the re-attached displacer unit 3 with its disk 17 can again produce the magnetic connection 16 from the lever 19 without being influenced by the permanent magnets 16 '.
- the lever 19 should be as in FIG Fig. 2e be shown shown.
- the guide sleeve 14 is inserted until the disc 17 rests against the short lever arm 22 and the magnetic force begins to act.
- the further magnetic connection 16 is gently and manually controlled coupled.
- the magnetic connection 11 can be manually separated downward in the direction of the arrow E after the release of the magnetic connection 16.
- the magnetic connection 11 can also be separated simultaneously with the magnetic connection 16 with the mechanical means 18 provided according to the invention.
- the ratio of the arm lengths of the lever 19 allows a manual light, ergonomic operation.
- the separation process is carried out in a controlled manner with one hand, the thumb presses the button 21 and keep other fingers the displacer unit 3 on the disc 17 against falling.
- Fig. 5a and 5b show a first alternative in the construction of the coupling device 4.
- the mechanical, manually operable means 18 for separating the magnetic connection 16 on the displacer unit 3 comprises an axially profiled cam disc 24 on a rotary wheel 21 'and on the drive unit 2 one to the cam disc 24 congruent cam guide 25 on.
- the magnetic connection 16 of the permanent magnet 16' and the disc 17 is made of soft iron separable.
- the rotary wheel 21 'with the cam disk 24 is rotatably mounted on the displacer unit 3. To separate the cam disk 24 is rotated about the longitudinal axis 10.
- the cam disk 24 has in the illustrated embodiment, a plurality, preferably three, axially projecting cams. Congruently profiled is provided on the drive unit 2 cam guide 25. In the comparison of Fig. 5a and Fig. 5b can be seen that by turning the displacer unit 3 relative to the drive unit 2, the cam disc 24 is rotated relative to the cam guide 25 and so the separation process takes place.
- the drive unit 2 is rotationally rigidly connected to the displacer unit 3 with the magnetic connection 16 closed, it can also be provided that the cam disc 24 is rotatably mounted on the displacer unit 3 itself. Then the Verdfiterussi 3 remains when disconnected from the drive unit 2 and only the cam plate 24 is rotated relative to the displacer unit 3 and with respect to the cam guide 25 on the drive unit 2.
- cam disc 24 and the cam guide 25 can also be chosen vice versa with respect to the drive unit 2 and the displacer unit 3.
- the displacer unit 3 By rotating the cam plate 24 relative to the cam guide 25, the displacer unit 3 is axially displaced by the drive unit 2 with a stroke similar to the embodiment with the lever arm 22 and the magnetic connection 16 (possibly together with it the magnetic connection 11) is separated.
- the magnetic means of the magnetic connection 16 as such or the displacer unit 3 and the drive unit 2 are rotatable relative to each other about the longitudinal axis 10 with the magnetic connection 16 closed.
- the drive unit 2 and the displacer unit 3 are rotatable relative to each other about the longitudinal axis 10 as the double arrow 26 in Fig. 6b makes it clear.
- the magnetic means 16 ', 17 of the magnetic connection 16 are congruent with each other and are thus fully effective.
- the in Fig. 6b cut position shown cut only the magnetic means 16 ' the means 17 are hidden below.
- the magnetic means 17 (shown in dashed lines) is offset from the means 16 '. They are therefore less effective or ineffective. This is the position at which the magnetic connection 16 can be separated with little effort.
- Fig. 6b is the second rotational position shown in dashed lines.
- Fig. 6b is structurally provided that the guide sleeve 14 adjacent to an outer ring 24 'at least one stop 14' has.
- Fig. 6b example shown are three stops 14 'formed on the guide sleeve 14 radially. They are in operative connection with the magnetic means 16 'of the drive unit 2.
- the stops 14 ' are hinged counterclockwise. From there, the rotational movement in the opposite direction, ie in a clockwise direction, bring the stops 14 'in the dashed position.
- the magnetic means 17 on the rotated displacer unit 3 are not congruent with the magnetic means 16 'of the drive unit 2, are magnetically ineffective.
- the magnetic means 16 'intersect; 17 only slightly, with their holding force is so low that the drive unit 2 and the displacer unit 3 can be easily separated manually and without much effort.
- the magnetic forces in the second rotational position are sufficient to be even higher than the weight of the displacer unit 3, so that the displacer unit 3 does not simply fall off the drive unit 2.
- Fig. 6a One recognizes in Fig. 6a in that the magnetic means 16 ', 17 are equidistant from the longitudinal axis 10. Furthermore one recognizes in Fig. 6b in that the magnetic means 16 'at the receiving portion 15 of the drive unit 2 are at the same distance relative to each other, namely at an angle of 120 ° with respect to the longitudinal axis 10.
- a holder 27 for the magnetic means 17 is provided on the displacer unit 3 which is rotatable relative to the magnetic means 16 'on the drive unit 2 and to the displacer unit 3.
- Fig. 7a is shown how to the holder 27 rotatably mounted on the guide sleeve 14, but is connected to it immovable axially.
- the magnetic means 16 ', 17 of drive unit 2 and displacer unit 3 are arranged congruent and effective or not congruent and ineffective, as described above.
- the drive unit 2 and the displacer unit 3 are rotationally rigidly connected, for which longitudinal congruent profilings 6 'are arranged on the receiving section 15 of the housing 6 and 14 "on the guide sleeve 14. These allow a connection of the drive unit 2 and the displacer unit 3 in at least a position Fig. 7b Only four positions offset by 90 ° are possible, but a higher number of positions is even more practicable.
- the rotational movement 26 of the holder 27 with the magnetic means 17 are limited by said abutment surfaces on the stops 14 '.
- the clockwise rotation 26 displaces the position of the magnetic means 17 away from the means 16 'in the drive unit 2 and the magnetic connection 16 becomes inoperative.
- a holding device for the displacer unit 3 is provided.
- a radially projecting collar 30 is integrally formed on the lateral surface of the guide sleeve 14.
- the catch 31 protrudes so far in the direction of the axis 10 that it comes to rest in the illustrated arrangement below the covenant 30 and in the range of movement in the direction of the axis 10.
- Fig. 4 the horizontal sectional view at the level of the catch 31, two opposing notches 31 are shown.
- the holding device 30, 31 causes the displacer unit 3 even after loosening the magnetic connection 16 (and the magnetic connection 11) still loosely attached to the drive unit 2, only mechanically held by the catches 31 on the collar 30. These can easily yield when force application so that the displacer unit 3 can be finally separated from the drive unit 2 with little effort. This results in an additional mechanical safeguard, which prevents accidental dropping of the displacer unit 3 by the drive unit 2.
- the holding device 30, 31 can be solved by downward pulling on the displacer unit 3.
- a special construction for example by means of a manually operable button or by means of any kind of actuator.
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Description
Die Erfindung betrifft eine Kolbenhubpipette mit einer Antriebseinheit und einer an der Antriebseinheit montierten Verdrängereinheit mit den Merkmalen des Oberbegriffs von Anspruch 1. Derartige Kolbenhubpipetten werden in der Praxis zum Transferieren von Flüssigkeit unter Nutzung von Pipettenspitzen verwendet.The invention relates to a piston stroke pipette with a drive unit and a displacer unit mounted on the drive unit with the features of the preamble of
Aus dem Stand der Technik
Das Lösen der beiden lösbaren mechanischen Verbindungen, die beide als Magnetverbindungen ausgeführt sind, erfolgt hier durch manuelles Auseinanderziehen von Antriebseinheit und Verdrängereinheit.The release of the two releasable mechanical connections, which are both designed as magnetic connections, takes place here by manual pulling apart of the drive unit and displacer unit.
Derartige Kolbenhubpipetten weisen als sogenannte Mehrkanalpipetten acht oder zwölf Kolben-Zylinder-Einheiten auf und bedürfen entsprechend hoher Betätigungskräfte. Gleiches tritt auch bei einkanaligen großvolumigen Pipetten auf. Die lösbaren mechanischen Verbindungen bzw. Kupplungseinrichtungen der Pipetten übertragen diese Kräfte, so dass deren Magnetkraft hoch sein muss. In der Praxis hat sich gezeigt, dass die Magnetkraft manuell nur schwer überwunden werden kann. Das Trennen erfolgt ruckartig, ist unangenehm und kann u.U. zu Verletzungen oder Beschädigungen führen. Beim Fügen der Verdrängereinheit an die Antriebseinheit durch die Magnetkraft kann es zwischen beiden Bauteilen ebenso zu Verletzungen kommen.Such Kolbenhubpipetten have as so-called multi-channel pipettes eight or twelve piston-cylinder units and require correspondingly high actuation forces. The same occurs with single-channel large-volume pipettes. The detachable mechanical connections or coupling devices of the pipettes transmit these forces, so that their magnetic force must be high. In practice it has been shown that the magnetic force can be overcome manually only with difficulty. The separation is jerky, is uncomfortable and may lead to injury or damage. When joining the displacer unit the drive unit due to the magnetic force can also cause injury between the two components.
Eine weitere Kolbenhubpipette ist aus der
Der Erfindung liegt das Problem zugrunde, die bekannte Kolbenhubpipette mit einer als Magnetverbindung ausgeführten lösbaren mechanischen Verbindung zwischen der Antriebseinheit und der Verdrängereinheit so auszugestalten und weiterzubilden, dass diese ergonomisch bedienbar und effektiv handhabbar ist.The invention is based on the problem of designing the known Kolbenhubpipette with a designed as a magnetic connection releasable mechanical connection between the drive unit and the displacer unit and further that it is ergonomically operable and effective to handle.
Das zuvor aufgezeigte Problem ist gelöst bei einer Kolbenhubpipette mit den Merkmalen des Oberbegriffs von Anspruch 1 durch die Merkmale des kennzeichnenden Teils von Anspruch 1.The above-indicated problem is solved in a piston stroke pipette with the features of the preamble of
Die Erfindung geht von dem Gedanken aus, die Magnetkraft zumindest der als Magnetverbindung ausgeführten lösbaren mechanischen Verbindung zwischen dem Aufnahmeabschnitt der Antriebseinheit und dem Befestigungsabschnitt der Verdrängereinheit mit einem zusätzlichen mechanischen Mittel zu überwinden oder hinreichend weit abzuschwächen. Der Bediener kann so von ihm selbst ausgelöst leicht und gefahrlos die Verdrängereinheit von der Antriebseinheit abnehmen. Die Verdrängereinheit kann in Gegenrichtung mit Hilfe des mechanischen Mittels zum Trennen der Magnetverbindung auch wieder sanft und kontrolliert an die Antriebseinheit angekuppelt werden.The invention is based on the idea of overcoming or adequately mitigating the magnetic force of at least the detachable mechanical connection designed as a magnetic connection between the receiving section of the drive unit and the fastening section of the displacer unit with an additional mechanical means. The operator can thus easily and safely remove the displacer unit from the drive unit. The displacer unit can in the opposite direction by means of the mechanical means for Disconnect the magnetic connection again gently and controlled to be coupled to the drive unit.
Die Magnetverbindung der erfindungsgemäßen Kolbenhubpipette ist praxistauglicher gestaltet als im Stand der Technik. Der Bediener der Kolbenhubpipette ist sicher in der Handhabung, wenn er die Antriebseinheit und die Verdrängereinheit voneinander trennt. Dies kann ohne großen manuellen Krafteinsatz erfolgen. Eine Verletzungsgefahr durch das ruckartige Lösen der Magnetverbindung ist ausgeschlossen. Auch das Zusammenfügen der Antriebseinheit und der Verdrängereinheit ist einfach und sicher möglich.The magnetic connection of the piston stroke pipette according to the invention is designed more practical than in the prior art. The operator of the piston-operated pipette is safe to handle when separating the drive unit and the displacer unit. This can be done without much manual effort. A risk of injury due to the jerky release of the magnetic connection is excluded. The assembly of the drive unit and the displacer unit is easily and safely possible.
Erfindungsgemäß ist das mechanische Mittel gemäß einer der drei folgenden Alternativen ausgestaltet.According to the invention, the mechanical means is designed according to one of the following three alternatives.
Gemäß einer ersten Alternative weist das mechanische Mittel einen Hebel auf, der
- mit einem Drehpunkt an der Antriebseinheit gelagert ist und bei manueller Betätigung auf die Verdrängereinheit wirkt und dadurch die Magnetverbindung trennt oder
- mit einem Drehpunkt an der Verdrängereinheit gelagert ist und bei manueller Betätigung auf die Antriebseinheit wirkt und dadurch die Magnetverbindung trennt.
- is mounted with a pivot point on the drive unit and acts on manual operation on the displacer unit and thereby separates the magnetic connection or
- is mounted with a fulcrum on the displacer unit and acts on manual operation on the drive unit and thereby separates the magnetic connection.
Gemäß einer zweiten Alternative weist das mechanische Mittel eine axial profilierte Nockenscheibe und eine zu der Nockenscheibe kongruente Nockenführung auf. Durch eine Drehbewegung der Nockenscheibe und der Nockenführung relativ zueinander ist die Magnetverbindung trennbar.According to a second alternative, the mechanical means comprises an axially profiled cam disc and a cam guide congruent with the cam disc. By a rotational movement of the cam and the cam guide relative to each other, the magnetic connection is separable.
Gemäß einer dritten Alternative weisen der Aufnahmeabschnitt der Antriebseinheit und der Befestigungsabschnitt der Verdrängereinheit je mindestens ein magnetisches Mittel der Magnetverbindung auf. Zumindest die magnetischen Mittel der Magnetverbindung sind bei geschlossener Magnetverbindung relativ zueinander drehbar. Die magnetischen Mittel sind in einer ersten Drehstellung deckungsgleich gegenüberliegend wirksam und in einer zweiten Drehstellung nicht deckungsgleich und damit wenig wirksam oder unwirksam. Das mechanische Mittel ist
- ein Halter für das magnetische Mittel an der Verdrängereinheit ist, der mitsamt dem magnetischen Mittel relativ zu dem magnetischen Mittel an der Antriebseinheit drehbar ist, oder
- ein Halter für das magnetische Mittel an der Antriebseinheit ist, der mitsamt dem magnetischen Mittel relativ zu den magnetischen Mittel an der Verdrängereinheit drehbar ist.
- a holder for the magnetic means on the displacer unit, which is rotatable together with the magnetic means relative to the magnetic means on the drive unit, or
- is a holder for the magnetic means on the drive unit, which is rotatable together with the magnetic means relative to the magnetic means on the displacer unit.
Bevorzugte Ausgestaltungen und Weiterbildungen der zuvor beschriebenen Kolbenhubpipette sind Gegenstand der Unteransprüche.Preferred embodiments and developments of the piston stroke pipette described above are the subject of the dependent claims.
Das mechanische Mittel zum Trennen der Magnetverbindung zwischen dem Aufnahmeabschnitt und dem Befestigungsabschnitt kann grundsätzlich von einem motorischen Aktor betätigbar sein. Ein Bediener betätigt dann nur ein Auslöseelement, beispielsweise einen Taster, und der Aktor treibt das mechanische Mittel zum Trennen der Magnetverbindung an und trennt diese Magnetverbindung.The mechanical means for separating the magnetic connection between the receiving portion and the attachment portion may be basically actuated by a motor actuator. An operator then actuates only one trigger element, for example a button, and the actuator drives the mechanical means for disconnecting the magnetic connection and disconnects this magnetic connection.
Besonders bevorzugt ist es allerdings, wenn das mechanische Mittel zum Trennen der Magnetverbindung ein manuell, also von Hand betätigbares Mittel ist. Das macht den Aufbau der Kolbenhubpipette einfach und kostengünstig.However, it is particularly preferred if the mechanical means for separating the magnetic connection is a manually, that is manually operable means. This makes the construction of the piston stroke pipette simple and inexpensive.
Mechanisch besonders robust und zweckmäßig ist eine Konstruktion, bei der die Magnetverbindung schlicht durch Wegdrücken der Verdrängereinheit von der Antriebseinheit oder umgekehrt trennbar ist. Die Magnetverbindung kann aber auch nur für sich getrennt werden, indem also die Bestandteile der Magnetverbindung auseinandergedrückt werden und dadurch die Haltekraft der Magnetverbindung so abgeschwächt wird, dass die Verdrängereinheit dann von der Antriebseinheit leicht abgenommen werden kann.Mechanically particularly robust and expedient is a construction in which the magnetic connection is simply separable by pushing away the displacer unit from the drive unit or vice versa. However, the magnetic connection can also be separated only by itself so that the components of the magnetic connection are pressed apart and thereby the holding force of the magnetic connection is weakened so that the displacer unit can then be easily removed by the drive unit.
Die lösbare mechanische Verbindung zwischen dem Betätigungsantrieb und dem Kolbenantrieb muss nicht als magnetische Verbindung ausgeführt sein. Im Stand der Technik ist sie als Magnetverbindung ausgeführt. Sie kann aber auch als Rastverbindung o. dgl. ausgeführt sein. Besonders bevorzugt ist es bei Ausführung als Magnetverbindung, dass diese dann ebenfalls durch Betätigung des manuell betätigbaren Mittels trennbar ist.The releasable mechanical connection between the actuating drive and the piston drive need not be designed as a magnetic connection. In the prior art, it is designed as a magnetic connection. But it can also be designed as a latching connection o. The like. In the case of a design as a magnetic connection, it is particularly preferable for it to be separable likewise by actuation of the manually operable means.
Besondere konstruktive Varianten der Lehre sind Gegenstand der Ansprüche 7 bis 11.Special structural variants of the teaching are the subject matter of
In einer weiter bevorzugten Ausgestaltung wird ein vollständiges Lösen auch bei getrennter Magnetverbindung vermieden, so dass die Verdrängereinheit nicht einfach von der Antriebseinheit herunterfällt. Das ist Gegenstand der Ansprüche 12 und 13.In a further preferred embodiment, a complete release is avoided even with a separate magnetic connection, so that the displacer unit does not simply fall off the drive unit. This is the subject matter of
Im Folgenden wird die Erfindung anhand einer verschiedene Ausführungsbeispiele nicht beschränkend darstellenden Zeichnung näher erläutert. Im Zuge der Erläuterung von Ausführungsbeispielen anhand der Zeichnung werden auch Vorteile und Besonderheiten verschiedener Ausführungsformen der Erfindung erörtert. In der Zeichnung zeigt
- Fig. 1
- eine erfindungsgemäße Kolbenhubpipette in perspektivischer Ansicht,
- Fig. 2
- ausschnittsweise, in vertikaler Schnittdarstellung, eine Antriebseinheit und den oberen Bereich einer daran montierten Verdrängereinheit der Kolbenhubpipette aus
Fig. 1 , - Fig. 2a bis 2f
- Darstellungen wie in
Fig. 2 mit unterschiedlichen Positionen der verschiedenen Teile der Kolbenhubpipette, die unterschiedlichen Betriebszuständen entsprechen, nämlich-
Fig. 2a die Ruhe-, Start- und Abgabeposition, -
Fig. 2b eine maximale Aufsaugposition, -
Fig. 2c eine Überhubposition, -
Fig. 2d eine Trennposition, -
Fig. 2e den Trennvorgang und -
Fig. 2f Montage und Demontage,
-
- Fig. 3
- ein Ausführungsbeispiel einer erfindungsgemäßen Kolbenhubpipette in einer Ansicht von vorn, im linken Teil des Gehäuses teilweise geöffnet,
- Fig. 4
- die Kolbenhubpipette aus
Fig. 3 in einer horizontalen Schnittdarstellung gemäß der Linie IV-IV inFig. 3 , - Fig. 5a
- eine weitere Ausführungsform einer erfindungsgemäßen Kolbenhubpipette, in der rechten Hälfte im Schnitt, Verdrängereinheit und Antriebseinheit gekuppelt,
- Fig. 5b
- die Kolbenhubpipette aus
Fig. 5a , die Magnetverbindung nun getrennt, - Fig. 6a
- ein weiteres Ausführungsbeispiel einer erfindungsgemäßen Kolbenhubpipette, in der rechten Hälfte im Schnitt, Verdrängereinheit und Antriebseinheit gekuppelt,
- Fig. 6b
- die Kolbenhubpipette aus
Fig. 6a in einer horizontalen Schnittdarstellung, - Fig. 7a
- im Schnitt ein weiteres Ausführungsbeispiel einer erfindungsgemäßen Kolbenhubpipette,
- Fig. 7b
- die Kolbenhubpipette aus
Fig. 7a in horizontaler Schnittdarstellung, - Fig. 8
- in einer
Fig. 2 entsprechenden Darstellung ein Ausführungsbeispiel einer Kolbenhubpipette mit einem manuell betätigbaren Mittel zum Trennen an der Verdrängereinheit.
- Fig. 1
- a piston stroke pipette according to the invention in a perspective view,
- Fig. 2
- Sectionally, in vertical sectional view, a drive unit and the upper portion of a displacer unit mounted thereon of the piston stroke pipette
Fig. 1 . - Fig. 2a to 2f
- Depictions like in
Fig. 2 with different positions of the various parts of the Kolbenhubpipette that correspond to different operating conditions, namely-
Fig. 2a the rest, start and discharge position, -
Fig. 2b a maximum absorption position, -
Fig. 2c an overstroke position, -
Fig. 2d a separation position, -
Fig. 2e the separation process and -
Fig. 2f Assembly and disassembly,
-
- Fig. 3
- an embodiment of a piston stroke pipette according to the invention in a front view, partially opened in the left part of the housing,
- Fig. 4
- the piston stroke pipette
Fig. 3 in a horizontal sectional view along the line IV-IV inFig. 3 . - Fig. 5a
- a further embodiment of a piston stroke pipette according to the invention, coupled in the right half in section, displacer unit and drive unit,
- Fig. 5b
- the piston stroke pipette
Fig. 5a , the magnetic connection now disconnected, - Fig. 6a
- another embodiment of a piston stroke pipette according to the invention, coupled in the right half in section, displacer unit and drive unit,
- Fig. 6b
- the piston stroke pipette
Fig. 6a in a horizontal sectional view, - Fig. 7a
- in section a further embodiment of a piston stroke pipette according to the invention,
- Fig. 7b
- the piston stroke pipette
Fig. 7a in horizontal section, - Fig. 8
- in a
Fig. 2 corresponding representation of an embodiment of a piston stroke pipette with a manually operable means for separating the displacer unit.
In
Die
Der Kolbenantrieb 9 ist seinerseits mit den in
Die hier dargestellte Ausführung der ersten mechanischen Verbindung als Magnetverbindung 11 besteht aus magnetischen Mitteln, nämlich einem Permanentmagneten 12 am Betätigungsantrieb 8 und einem Weicheisenkern 13 am Kolbenantrieb 9. Die gezeigte Magnetverbindung 11 kann auch durch zwei Permanentmagnete oder evtl. auch durch einen elektrisch abschaltbaren Magneten realisiert werden. Diese die Antriebsbewegung übertragende Verbindung 11 ist ausreichend dimensioniert, aber dennoch bei zur normalen Bewegung überhöhter Krafteinleitung trennbar. Die Trennbarkeit kann je nach Verbindungsart durch Lösen und/oder Entfernen der oder weiter notwendiger Bauteile ermöglicht werden.The embodiment of the first mechanical connection shown here as a
Das obere Ende der Verdrängereinheit 3 hat einen Befestigungsabschnitt 14, 17 mit einer Führungshülse 14, die koaxial zur Achse 10 in einen Aufnahmeabschnitt 15 der Antriebseinheit 2 eingeschoben ist. Im Inneren der Führungshülse 14 befinden sich der Betätigungsantrieb 8, der Kolbenantrieb 9 und die erste mechanische Verbindung 11 hier in Form der Magnetverbindung 11.The upper end of the
Eine zweite mechanische Verbindung 16 der Kupplungseinrichtung 4 in Form einer Magnetverbindung 16 besteht zwischen dem Aufnahmeabschnitt 15 der Antriebseinheit 2 und dem Betätigungsabschnitt 14 der Verdrängereinheit 3, also der Führungshülse 14. In der dargestellten und in
Wie man insbesondere
Wie bereits oben angemerkt worden ist, ist auch die erste lösbare mechanische Verbindung 11 zwischen dem Betätigungsantrieb 8 und dem Kolbenantrieb 9 als Magnetverbindung 11 ausgeführt. Diese kann durch Betätigen des manuell betätigbaren Mittels 18 zum Trennen der Magnetverbindung 16 ebenfalls getrennt werden. Im Einzelnen wird das weiter unten noch erläutert.As has already been noted above, the first releasable
Bei der in
In
Das in
Das in
Das in
Vorzugsweise ist vorgesehen, dass der Hubweg des Hebelarms 22 beim manuellen Betätigen zum Zwecke des Trennens etwa 0,3 mm bis 2,0 mm, vorzugsweise etwa 1,0 mm, beträgt. Das gilt für das hier dargestellte und insoweit bevorzugte Ausführungsbeispiel.It is preferably provided that the stroke of the
Die nicht dargestellte Pipettenspitze wird in die Flüssigkeit eingetaucht. Zum anschließenden Ansaugen wird der Betätigungsantrieb 8 eingefahren, also der Kolbenantrieb 9 mit dem nicht dargestellten Kolben im Zylinder in der Darstellung nach oben verlagert. Der Hub A wird bei einer manuellen Kolbenhubpipette1 durch nicht dargestellte Anschläge begrenzt oder bei einer elektromotorischen Kolbenhubpipette1 beispielsweise durch die vorgewählten Umdrehungen des Antriebs definiert. Den maximalen Hub A zeigt
Zum Abgeben der Flüssigkeit aus der Pipettenspitze in ein anderes Gefäß wird der Kolben in die Startposition von
Soll die Verdrängereinheit 3 ausgetauscht oder eine andere, beispielsweise eine mit größerem Kolben oder eine mit einer anderen Anzahl an Kanälen, verwendet werden, so ist dies wegen der Kupplungseinrichtung 4 möglich.If the
Bei der dargestellten Ausführungsform sind der Betätigungsantrieb 8 und der Kolbenantrieb 9 durch die erste Magnetverbindung 11 verbunden und werden, wie
Der Kolbenantrieb 9 wird in seiner Aufwärtsbewegung durch einen Anschlag festgehalten. Der Betätigungsantrieb 8 wird mittels des Hubaktors 7 ein wenig weiter nach oben gefahren. Dadurch trennt sich der Permanentmagnet 12 vom Weicheisenkern 13. Die erste mechanische Verbindung in Form der Magnetverbindung 11 ist getrennt. An dieser Beschreibung lässt sich erkennen, dass in diesem Fall das mechanische Mittel 18 zum Trennen für die erste mechanische Verbindung 11 keine Funktion hat.The
Die stärkere Magnetverbindung 16 zwischen den Permanentmagneten 16' und der Scheibe 17 aus Weicheisen oder aus magnetischem Material wird durch das weiter vorgesehene mechanische, manuell betätigbare Mittel 18 getrennt.
Der Hubweg D ist in
Grundsätzlich ist es auch möglich, das Abziehen der Verdrängereinheit 3 mit einem Aktuator zu bewerkstelligen, beispielsweise indem die Verdrängereinheit 3 in einer Ablage festgehalten und die Antriebseinheit 2 angehoben wird. Bei einer alternativen Ausführung kann das Schalten von Rasten in die sperrende und freigebende Position mittels eines Aktuators realisiert werden. Ebenso beim manuellen oder aktuatorischen Ablegen der Verdrängereinheit 3 in eine Ablage kann der Schaltvorgang initiiert werden.In principle, it is also possible to accomplish the removal of the
In
In
Bestimmungsgemäß sollte beim Wiederanfügen der Verdrängereinheit 3 der Hebel 19 wie in
In der Folge wird der Hubaktor 7 gestartet und Betätigungsantrieb 8 mit dem Permanentmagneten 12 fährt in die in
Alternativ zu der insoweit bevorzugten Ausführung kann die Magnetverbindung 11 nach dem Lösen der Magnetverbindung 16 manuell in Richtung des Pfeils E nach unten getrennt werden.As an alternative to the preferred embodiment, the
Die Magnetverbindung 11 kann auch gleichzeitig mit der Magnetverbindung 16 mit dem erfindungsgemäß vorgesehenen mechanischen Mittel 18 getrennt werden.The
Das Verhältnis der Armlängen des Hebels 19 erlaubt eine manuell leichte, ergonomische Betätigung. Der Trennvorgang erfolgt dabei kontrolliert mit einer Hand, wobei der Daumen die Taste 21 betätigt und weitere Finger die Verdrängereinheit 3 an der Scheibe 17 gegen Herabfallen halten.The ratio of the arm lengths of the
Beide alternative Ausführungen schonen den Antrieb des Hubaktors 7, der gegenüber der Hubbewegung des Kolbenantriebs 9 mit erhöhter Antriebsleistung die Magnetverbindung 11 trennt (
Die Nockenscheibe 24 weist im dargestellten Ausführungsbeispiel mehrere, vorzugsweise drei, axial vorstehende Nocken auf. Dazu kongruent profiliert ist die an der Antriebseinheit 2 vorgesehene Nockenführung 25. Im Vergleich von
Ist die Antriebseinheit 2 mit der Verdrängereinheit 3 bei geschlossener Magnetverbindung 16 drehstarr verbunden, so kann man auch vorsehen, dass die Nockenscheibe 24 an der Verdrängereinheit 3 selbst drehbar gelagert ist. Dann bleibt die Verdängereinheit 3 beim Trennen gegenüber der Antriebseinheit 2 stehen und nur die Nockenscheibe 24 wird, gegenüber der Verdrängereinheit 3 und gegenüber der Nockenführung 25 an der Antriebseinheit 2, gedreht.If the
Die Anordnung der Nockenscheibe 24 und der Nockenführung 25 kann auch bzgl. der Antriebseinheit 2 und der Verdrängereinheit 3 umgekehrt gewählt werden.The arrangement of the
Durch Drehen der Nockenscheibe 24 gegenüber der Nockenführung 25 wird die Verdrängereinheit 3 von der Antriebseinheit 2 mit einem Hubweg ähnlich dem Ausführungsbeispiel mit dem Hebelarm 22 axial verlagert und die Magnetverbindung 16 (evtl. mit ihr gemeinsam auch die Magnetverbindung 11) wird getrennt.By rotating the
Eine weitere Variante für das mechanische, manuell betätigbare Mittel 18 zum Trennen zeigen
Im dargestellten Ausführungsbeispiel sind die Antriebseinheit 2 und die Verdrängereinheit 3 insgesamt relativ zueinander um die Längsachse 10 drehbar, wie das der Doppelpfeil 26 in
In
In der zweiten Drehstellung stehen die magnetischen Mittel 17 an der gedrehten Verdrängereinheit 3 nicht deckungsgleich zu den magnetischen Mitteln 16' der Antriebseinheit 2, sind magnetisch unwirksam. Alternativ überschneiden sich die magnetischen Mittel 16'; 17 nur noch geringfügig, wobei ihre Haltekraft so gering ist, dass die Antriebseinheit 2 und die Verdrängereinheit 3 leicht und ohne großen Kraftaufwand manuell getrennt werden können. Vorzugsweise reichen die Magnetkräfte in der zweiten Drehstellung aus, um noch höher als die Gewichtskraft der Verdrängereinheit 3 zu sein, so dass die Verdrängereinheit 3 nicht einfach von der Antriebseinheit 2 herabfällt.In the second rotational position, the magnetic means 17 on the rotated
Man erkennt in
In einer weiter bevorzugten Ausführungsform nach
In dieser Ausführung sind die Antriebseinheit 2 und die Verdrängereinheit 3 drehstarr verbunden, wozu längsgerichtete kongruente Profilierungen 6' an dem Aufnahmeabschnitt 15 des Gehäuses 6 und 14" an der Führungshülse 14 angeordnet sind. Diese ermöglichen eine Verbindung der Antriebseinheit 2 und der Verdrängereinheit 3 in mindestens einer Stellung. In
Die Drehbewegung 26 des Halters 27 mit den magnetischen Mitteln 17 werden durch besagte Anschlagflächen an den Anschlägen 14' begrenzt. Die Drehbewegung 26 im Uhrzeigersinn verlagert die Position der magnetischen Mittel 17 weg von den Mitteln 16' in der Antriebseinheit 2 und die Magnetverbindung 16 wird unwirksam.The
Nicht dargestellt sind weitere Rasten und Federn, die die Drehbewegung 26 steuern und Drehstellungen unterstützen. Ebenso nicht gezeigt ist die Kombination von Ausführungsformen, beispielsweise von
Bei der Ausführungsform nach
Die Haltevorrichtung 30, 31 führt dazu, dass die Verdrängereinheit 3 auch nach Lösen der Magnetverbindung 16 (und der Magnetverbindung 11) noch locker an der Antriebseinheit 2 hängt, nur noch mechanisch gehalten von den Rasten 31 am Bund 30. Diese können bei Kraftaufbringung leicht zurückweichen, so dass man die Verdrängereinheit 3 mit geringem Kraftaufwand endgültig von der Antriebseinheit 2 trennen kann. Dadurch ergibt sich eine zusätzliche mechanische Sicherung, die ein versehentliches Herabfallen der Verdrängereinheit 3 von der Antriebseinheit 2 vermeiden lässt.The holding
Im dargestellten Ausführungsbeispiel lässt sich die Haltevorrichtung 30, 31 durch abwärts gerichtetes Ziehen an der Verdrängereinheit 3 lösen. Alternativ kann man für die Haltevorrichtung 30, 31 auch eine besondere Konstruktion, beispielsweise mittels einer manuell betätigbaren Taste oder mittels eines irgendwie gearteten Aktors vorsehen.In the illustrated embodiment, the holding
Claims (13)
- Piston stroke pipette with a drive unit (2), and with a displacement unit (3) which is mounted on the drive unit (2) and which has a piston drive (9) for at least one piston (9'),
wherein the displacement unit (3) is dismountable from the drive unit (2),
wherein the drive unit (2) has an actuating drive (8) for the piston drive (9) and a receiving portion (15) for the displacement unit (3),
wherein the displacement unit (3) has a fastening portion (14) which fits the receiving portion (15) of the drive unit (2),
wherein a first detachable mechanical connection (11) is provided between the actuating drive (8) and the piston drive (9), and a second detachable mechanical connection (16) is provided between the receiving portion (15) of the drive unit (2) and the fastening portion (14) of the displacement unit (3), and
wherein at least the second detachable mechanical connection (16) is configured as a magnetic connection (16),
characterized in that
a mechanical means (18) is provided for separating and coupling the magnetic connection (16) between the receiving portion (15) and the fastening portion (14),
and- in that the mechanical means (18) has a lever (19) which- is supported on the drive unit (2) with a fulcrum (20) and, when manually actuated, acts on the displacement unit (3) and thereby separates the magnetic connection (16), or- is supported on the displacement unit (3) with a fulcrum (20) and, when manually actuated, acts on the drive unit (2) and thereby separates the magnetic connection (16), or- in that the mechanical means (18) has an axially profiled cam disc (24) and a cam guide (25) which is congruent to the cam disc (24), and in that the magnetic connection (16) is separable by a rotary movement of the cam disc (24) and the cam guide (25) relative to each other, or- the receiving portion (15) of the drive unit (2) and the fastening portion (14) of the displacement unit (3) each have at least one magnetic means (16'; 17) of the magnetic connection (16), in that at least the magnetic means (16'; 17) of the magnetic connection (16) are rotatable relative to each other when the magnetic connection (16) is closed, and in that the magnetic means (16'; 17), in a first rotary position, are opposite and congruent to each other and active and, in a second rotary position, are non-congruent and thus inactive or substantially inactive, and in that the mechanical means (18)- is a holder (24', 27) for the magnetic means (17) on the displacement unit (3), which holder (24', 27) is rotatable together with the magnetic means (17) relative to the magnetic means (16') on the drive unit (2), or- is a holder (27) for the magnetic means (16') on the drive unit (2), which holder (27) is rotatable together with the magnetic means (16') relative to the magnetic means (17) on the displacement unit (3). - Piston stroke pipette according to Claim 1, characterized in that the mechanical means (18) is a manually actuatable means.
- Piston stroke pipette according to Claim 1, characterized in that the mechanical means (18) is actuatable by a motor actuator, wherein the actuator is manually actuatable by an operator via a trigger element.
- Piston stroke pipette according to one of Claims 1 to 3, characterized in that the magnetic connection (16) is separable by forcing the displacement unit (3) away from the drive unit (2) or by forcing the drive unit (2) away from the displacement unit (3).
- Piston stroke pipette according to one of Claims 1 to 4, characterized in that the separating movement of drive unit (2) and displacement unit (3) is an axial movement along a common longitudinal axis (10).
- Piston stroke pipette according to one of Claims 1 to 5, characterized in that the first detachable mechanical connection (11) is likewise configured as a magnetic connection (11), and in that the magnetic connection (11) between the actuating drive (8) and the piston drive (9) is also separable by actuation of the mechanical means (18).
- Piston stroke pipette according to one of Claims 1 to 6, characterized in that the lever (19) has a manually actuatable pushbutton (21) which- is actuatable in a direction that is transverse to the direction of the separating movement of drive unit (2) and displacement unit (3), and/or- is arranged above the fulcrum (20) of the lever (19) .
- Piston stroke pipette according to Claim 7, characterized in that, for the separation of the magnetic connection (16), the lever (19) has a lever arm (22), and in that- the distance of the pushbutton (21) from the fulcrum (20) of the lever (19) is substantially longer than the lever arm (22), preferably six times as long as the lever arm (22) of the lever (19), and/or- the travel of the lever arm (22) during the manual actuation for the purpose of separation is 0.3 to 2.0 mm, preferably 1.0 mm.
- Piston stroke pipette according to one of Claims 1 to 8, characterized in that the drive unit (2) and the displacement unit (3) are connected to each other in a rotationally rigid manner when the magnetic connection (16) is closed.
- Piston stroke pipette according to one of Claims 1 to 6, characterized in that
the cam disc (24) is arranged on the displacement unit (3) and the cam guide (25) is arranged on the drive unit (2), and
in that preferably the cam disc (24) is mounted rotatably on the displacement unit (3) and only the cam disc (24) is rotated for the purpose of separation. - Piston stroke pipette according to Claim 1, characterized in that the magnetic means (16'; 17) are at the same distance from the longitudinal axis (10) and, in the case of a plurality of magnetic means (16'; 17) on the drive unit (2) and/or the displacement unit (3), these are also at a same distance relative to each other.
- Piston stroke pipette according to one of Claims 1 to 11, characterized in that a mechanical retaining device (30, 31) is provided which detachably limits the separating movement of drive unit (2) and displacement unit (3), wherein the displacement unit (3) is removable from the drive unit (2) with a small actuating force after the magnetic connection (16) is separated.
- Piston stroke pipette according to one of Claims 1 to 11, characterized in that a mechanical retaining device (30, 31) is provided which detachably limits the separating movement of drive unit (2) and displacement unit (3), wherein the retaining device (30, 31) is detachable manually or by means of an actuator.
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DE202012011043 | 2012-11-19 |
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USD772426S1 (en) * | 2014-01-13 | 2016-11-22 | Gilson, Inc. | Pipette system cartridge |
DE102016121815A1 (en) * | 2016-11-14 | 2018-05-17 | Ika-Werke Gmbh & Co. Kg | manual proportioning device |
USD924429S1 (en) | 2019-02-21 | 2021-07-06 | Brand Gmbh + Co Kg | Handheld pipette |
JP2024523840A (en) * | 2021-06-11 | 2024-07-02 | キアル・ベー・フェー | DEVICE WITH INTERFACE FOR RELEASEABLE COUPLING OF A CUTTING TOOL - Patent application |
USD1031074S1 (en) | 2022-04-06 | 2024-06-11 | Brand Gmbh + Co Kg | Displacement device of a multi-channel pipette |
EP4349470A1 (en) * | 2022-10-06 | 2024-04-10 | Sartorius Stedim Biotech GmbH | Holding device for a container, comprising a magnetic drive for a separate stirring shaft |
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EP0181957A1 (en) * | 1984-11-20 | 1986-05-28 | HTL High-Tech Lab Herstellung und Vertrieb medizinisch technischer Erzeugnisse GmbH | Adjustable-volume pipette |
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EP0801309A3 (en) * | 1996-04-08 | 1998-08-12 | SANYO ELECTRIC Co., Ltd. | Pipetting apparatus |
DE19826065C2 (en) | 1998-06-12 | 2000-05-18 | Eppendorf Geraetebau Netheler | Pipetting device |
DE29924175U1 (en) * | 1999-10-09 | 2002-03-28 | RETEC elektronische Regeltechnik GmbH, 74360 Ilsfeld | Fluid intake and delivery system |
US6428750B1 (en) * | 2000-02-17 | 2002-08-06 | Rainin Instrument, Llc | Volume adjustable manual pipette with quick set volume adjustment |
WO2002029419A2 (en) | 2000-10-06 | 2002-04-11 | Chemspeed Ltd. | Device comprising a tool holder and a removably attachable tool |
US7976793B2 (en) | 2003-11-27 | 2011-07-12 | Gilson S.A.S. | Electronic pipette |
FI116612B (en) * | 2004-07-05 | 2006-01-13 | Biohit Oyj | A suction device |
DE102005023203B4 (en) * | 2005-05-20 | 2009-06-04 | Eppendorf Ag | pipette |
US7690293B2 (en) * | 2007-01-05 | 2010-04-06 | Ivek Corporation | Coupling system for use with fluid displacement apparatus |
DE102007006076B4 (en) | 2007-02-02 | 2008-10-30 | Brand Gmbh + Co Kg | Multichannel pipetting |
DE102007042115B4 (en) | 2007-09-05 | 2010-12-02 | Eppendorf Ag | pipette |
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US7947234B2 (en) | 2007-10-17 | 2011-05-24 | Rainin Instrument, Llc | Liquid end assembly for a handheld multichannel pipette with adjustable nozzle spacing |
US20090117009A1 (en) * | 2007-11-02 | 2009-05-07 | Richard Cote | Multi-channel electronic pipettor |
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2013
- 2013-11-08 EP EP13005269.9A patent/EP2732877B1/en active Active
- 2013-11-19 US US14/083,899 patent/US9364827B2/en active Active
Non-Patent Citations (1)
Title |
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None * |
Also Published As
Publication number | Publication date |
---|---|
EP2732877A1 (en) | 2014-05-21 |
US9364827B2 (en) | 2016-06-14 |
US20140137672A1 (en) | 2014-05-22 |
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