EP2642278C0 - Capteur d'analyte à fibre optique - Google Patents

Capteur d'analyte à fibre optique

Info

Publication number
EP2642278C0
EP2642278C0 EP13159750.2A EP13159750A EP2642278C0 EP 2642278 C0 EP2642278 C0 EP 2642278C0 EP 13159750 A EP13159750 A EP 13159750A EP 2642278 C0 EP2642278 C0 EP 2642278C0
Authority
EP
European Patent Office
Prior art keywords
fiber optic
analyte sensor
optic analyte
sensor
fiber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP13159750.2A
Other languages
German (de)
English (en)
Other versions
EP2642278B1 (fr
EP2642278A3 (fr
EP2642278A2 (fr
Inventor
John Eastman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Modern Controls Inc
Original Assignee
Mocon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mocon Inc filed Critical Mocon Inc
Publication of EP2642278A2 publication Critical patent/EP2642278A2/fr
Publication of EP2642278A3 publication Critical patent/EP2642278A3/fr
Application granted granted Critical
Publication of EP2642278C0 publication Critical patent/EP2642278C0/fr
Publication of EP2642278B1 publication Critical patent/EP2642278B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N21/643—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" non-biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G01N21/783—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour for analysing gases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6434—Optrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Instruments For Viewing The Inside Of Hollow Bodies (AREA)
  • Endoscopes (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
EP13159750.2A 2012-03-22 2013-03-18 Capteur d'analyte à fibre optique Active EP2642278B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13/426,831 US11293866B2 (en) 2012-03-22 2012-03-22 Fiber optic analyte sensor

Publications (4)

Publication Number Publication Date
EP2642278A2 EP2642278A2 (fr) 2013-09-25
EP2642278A3 EP2642278A3 (fr) 2013-10-02
EP2642278C0 true EP2642278C0 (fr) 2023-07-05
EP2642278B1 EP2642278B1 (fr) 2023-07-05

Family

ID=47891518

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13159750.2A Active EP2642278B1 (fr) 2012-03-22 2013-03-18 Capteur d'analyte à fibre optique

Country Status (3)

Country Link
US (1) US11293866B2 (fr)
EP (1) EP2642278B1 (fr)
JP (1) JP2013192946A (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11293866B2 (en) 2012-03-22 2022-04-05 John EASTMAN Fiber optic analyte sensor
US9316554B1 (en) 2014-12-23 2016-04-19 Mocon, Inc. Fiber optic analyte sensor with integrated in situ total pressure correction
US10295514B1 (en) * 2016-10-17 2019-05-21 Mocon, Inc. Instrument and method for sealed penetration of rigid packaging to measure internal oxygen concentration with an optical oxygen analyzer

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476870A (en) 1982-03-30 1984-10-16 The United States Of America As Represented By The Department Of Health And Human Services Fiber optic PO.sbsb.2 probe
US4622974A (en) 1984-03-07 1986-11-18 University Of Tennessee Research Corporation Apparatus and method for in-vivo measurements of chemical concentrations
US4810655A (en) 1985-07-03 1989-03-07 Abbott Laboratories Method for measuring oxygen concentration
US5190729A (en) 1986-09-08 1993-03-02 C. R. Bard, Inc. Luminescent oxygen sensor based on a lanthanide complex
US5173432A (en) 1987-12-14 1992-12-22 The Dow Chemical Company Apparatus and method for measuring the concentration or partial pressure of oxygen
WO1992019150A1 (fr) 1991-05-03 1992-11-12 Innerspace, Inc. Sonde d'insertion directe dans les tissus d'un patient
US5230427A (en) 1991-06-12 1993-07-27 Ppg Industries, Inc. Sterilizable hermetically-sealed substantially glass container
US5718842A (en) 1994-10-07 1998-02-17 Joanneum Reserach Forschungsgesellschaft Mbh Luminescent dye comprising metallocomplex of a oxoporphyrin
DE69727069T2 (de) 1996-10-08 2004-11-04 Photonics Biosystems, Redmond Mikrobiologisches schnellbestimmungsverfahren und vorrichtung, die die detektion des sauerstoffgradienten benutzt
US6410255B1 (en) 1999-05-05 2002-06-25 Aurora Biosciences Corporation Optical probes and assays
US6689438B2 (en) 2001-06-06 2004-02-10 Cryovac, Inc. Oxygen detection system for a solid article
EP1465730B1 (fr) 2002-01-17 2011-03-09 University College Cork - National University of Ireland, Cork Dispositif et procede de test pour realiser un criblage chimique ou biologique
US6684680B2 (en) 2002-06-03 2004-02-03 Optical Sensors, Inc. Cartridge for packaging a sensor in a fluid calibrant
JP3653536B2 (ja) 2002-06-21 2005-05-25 独立行政法人航空宇宙技術研究所 光学的酸素濃度測定方法及び光学的酸素濃度測定用センサ
US7368153B2 (en) 2002-12-06 2008-05-06 Cryovac, Inc. Oxygen detection system for a rigid container
JP2006522329A (ja) 2003-03-07 2006-09-28 ラクセル・バイオサイエンシズ・リミテッド 酸素感受性プローブ
US7787923B2 (en) 2003-11-26 2010-08-31 Becton, Dickinson And Company Fiber optic device for sensing analytes and method of making same
US7534615B2 (en) 2004-12-03 2009-05-19 Cryovac, Inc. Process for detecting leaks in sealed packages
US20060144811A1 (en) 2005-01-05 2006-07-06 Lifetime Hoan Corporation Oxygen absorbing appliance
DE102005024578A1 (de) 2005-05-25 2006-11-30 Raumedic Ag Sonde zur Messung des Sauerstoffgehaltes in biologischem Gewebe sowie Katheter mit einer derartigen Sonde
US20060200183A1 (en) 2005-03-01 2006-09-07 Gardocki Raymond J Multi-functional medical instrument and methods of use
GB0505036D0 (en) 2005-03-11 2005-04-20 Oxford Optronix Ltd An optical measurement sensor
JP5124751B2 (ja) 2005-04-15 2013-01-23 ラクセル・バイオサイエンシズ・リミテッド 生物学的又は化学的試料の評価
JP4358785B2 (ja) 2005-05-27 2009-11-04 麒麟麦酒株式会社 密封容器内の酸素量の測定方法及びこれに用いる密封容器のピアス装置
WO2006130528A1 (fr) 2005-06-02 2006-12-07 Glaxo Group Limited Capteur d'oxygene a distance alimente par induction
EP1742039A1 (fr) 2005-07-07 2007-01-10 F. Hoffmann-La Roche Ltd. Méthode pour la mesure de la concentration d'un analyte non-volatile.
US7569395B2 (en) 2006-03-13 2009-08-04 Cryovac, Inc. Method and apparatus for measuring oxygen concentration
DE102006014495B4 (de) 2006-03-29 2014-06-05 Sartorius Stedim Biotech Gmbh Vorrichtung zum Nehmen von Proben aus Systemen mit flexiblen Wandungen und zum Eintragen von Fluiden in solche
US20070243618A1 (en) 2006-04-11 2007-10-18 Oxysense, Inc. Device and method for non-invasive oxygen sensing of sealed packages
WO2008012785A2 (fr) 2006-07-24 2008-01-31 University College Cork - National University Of Ireland, Cork Sonde d'oxygène cellulaire
GB0619060D0 (en) 2006-09-27 2006-11-08 Glaxosmithkline Biolog Sa Novel process
US7679745B2 (en) 2006-11-21 2010-03-16 Neptec Optical Solutions Time-resolved fluorescence spectrometer for multiple-species analysis
US8242162B2 (en) 2006-12-15 2012-08-14 Ohio Aerospace Institute Fluorescent aromatic sensors and their methods of use
US8095196B2 (en) 2006-12-19 2012-01-10 Terumo Cardiovascular Systems Microsensor needle for pH measurement in tissue
US7849729B2 (en) 2006-12-22 2010-12-14 The Boeing Company Leak detection in vacuum bags
US20080199360A1 (en) 2007-02-16 2008-08-21 Ocean Optics, Inc. Method and composition for a platinum embedded sol gel optical chemical sensor with improved sensitivity and chemical stability
CA2668421A1 (fr) 2008-06-27 2009-12-27 Tyco Healthcare Group Lp Systeme et methode de detection optique continue de substance a analyser dans la circulation sanguine
US8323978B2 (en) 2008-11-07 2012-12-04 Mocon, Inc. Calibration system and technique for photoluminescent oxygen sensors with zero point maintained with a metal-air battery
JP2012508378A (ja) 2008-11-07 2012-04-05 モコン・インコーポレーテッド 光学式酸素センサ用キャリブレーションカード
US8481096B2 (en) 2009-01-07 2013-07-09 General Mills, Inc. Microwave foam product with blue or purple inclusions
US20110136247A1 (en) 2009-12-07 2011-06-09 Dmitri Boris Papkovsky Photoluminescent oxygen probe with reduced cross-sensitivity to humidity
US8694069B1 (en) 2009-12-21 2014-04-08 Kosense, LLC Fiber-optic probe with embedded peripheral sensors for in-situ continuous monitoring
US20130177480A1 (en) 2010-03-16 2013-07-11 Richard Fernandes Photoluminescent analyte partial volume probe set
US20120129268A1 (en) 2010-11-19 2012-05-24 Mayer Daniel W Photoluminescent oxygen probe with reduced cross-sensitivity to humidity
US9568400B2 (en) 2011-08-09 2017-02-14 Streamline Automation Llc Sampling adapter
US11293866B2 (en) 2012-03-22 2022-04-05 John EASTMAN Fiber optic analyte sensor
US9057687B2 (en) 2012-04-20 2015-06-16 Mocon, Inc. Calibration vial and technique for calibrating a fiber optic oxygen sensing needle
WO2014152194A1 (fr) 2013-03-15 2014-09-25 Kenneth Susko Sonde optique contenant des capteurs d'oxygène, de température et de pression et systèmes de surveillance et de contrôle contenant cette sonde
US9316554B1 (en) 2014-12-23 2016-04-19 Mocon, Inc. Fiber optic analyte sensor with integrated in situ total pressure correction

Also Published As

Publication number Publication date
EP2642278B1 (fr) 2023-07-05
JP2013192946A (ja) 2013-09-30
US20130251593A1 (en) 2013-09-26
EP2642278A3 (fr) 2013-10-02
EP2642278A2 (fr) 2013-09-25
US11293866B2 (en) 2022-04-05

Similar Documents

Publication Publication Date Title
GB2503498B (en) Fibre optic sensing
GB2500255B (en) Optical sensor
GB2489760B (en) Fibre optic distributed sensing
HK1209997A1 (en) Fiber optic sensor assembly for sensor delivery device
IL225047A0 (en) Optical fiber sensing system
ZA201502421B (en) Fiber optic cassette
GB2501422B (en) Fibre optic distributed sensing
EP2936117A4 (fr) Capteur optique de coagulation sanguine
EP2904389A4 (fr) Capteurs microfluidiques à signaux optiques améliorés
EP2905817A4 (fr) Capteur de lumière
GB201019117D0 (en) Distributed optical fibre sensor
EP2904376A4 (fr) Capteur optique pour détection d'analytes
GB2493771B (en) Optical sensor
GB2503466B (en) Optical sensor
GB201111030D0 (en) Optical fibre sensor interrogation system
GB2500256B (en) Optical pressure sensor
EP2894677A4 (fr) Unité de capteur optique
EP2821824A4 (fr) Fibre optique à plusieurs c urs
EP2894498A4 (fr) Fibre optique
EP2808654A4 (fr) Capteur en fibre
EP2860502A4 (fr) Capteur de température à fibres optiques
EP2829951A4 (fr) Capteur optique
EP2706388A4 (fr) Sonde optique
EP2813806A4 (fr) Capteur optique
EP2761414A4 (fr) Capteur de proximité à fibre optique

Legal Events

Date Code Title Description
PUAL Search report despatched

Free format text: ORIGINAL CODE: 0009013

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

AK Designated contracting states

Kind code of ref document: A3

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 21/77 20060101ALI20130827BHEP

Ipc: G01N 21/78 20060101ALI20130827BHEP

Ipc: G01N 21/64 20060101AFI20130827BHEP

17P Request for examination filed

Effective date: 20140327

RBV Designated contracting states (corrected)

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

17Q First examination report despatched

Effective date: 20160803

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: GRANT OF PATENT IS INTENDED

INTG Intention to grant announced

Effective date: 20230120

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE PATENT HAS BEEN GRANTED

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 1585273

Country of ref document: AT

Kind code of ref document: T

Effective date: 20230715

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602013084154

Country of ref document: DE

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

U01 Request for unitary effect filed

Effective date: 20230705

U07 Unitary effect registered

Designated state(s): AT BE BG DE DK EE FI FR IT LT LU LV MT NL PT SE SI

Effective date: 20230712

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG9D

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20231006

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20230705

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20231105

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: RS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20230705

Ref country code: NO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20231005

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20231105

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20230705

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20231006

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20230705

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20230705

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 602013084154

Country of ref document: DE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SM

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20230705

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20230705

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20230705

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20230705

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20240328

Year of fee payment: 12

U20 Renewal fee paid [unitary effect]

Year of fee payment: 12

Effective date: 20240325

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed

Effective date: 20240408