EP2576553A4 - Hochselektive asymmetrische hydroformylierung aus (1s,4r)- oder (1r,4s)-2-azabicyclo-[2.2.1-]hept-5-en-3-on(+)- oder (-)-lactam - Google Patents
Hochselektive asymmetrische hydroformylierung aus (1s,4r)- oder (1r,4s)-2-azabicyclo-[2.2.1-]hept-5-en-3-on(+)- oder (-)-lactamInfo
- Publication number
- EP2576553A4 EP2576553A4 EP11787411.5A EP11787411A EP2576553A4 EP 2576553 A4 EP2576553 A4 EP 2576553A4 EP 11787411 A EP11787411 A EP 11787411A EP 2576553 A4 EP2576553 A4 EP 2576553A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- azabicyclo
- hept
- lactam
- highly selective
- asymmetric hydroformylation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/32—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C271/36—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34889010P | 2010-05-27 | 2010-05-27 | |
PCT/US2011/038134 WO2011150205A2 (en) | 2010-05-27 | 2011-05-26 | Highly selective asymmetric hydroformylation of (1s,4r) or (1r,4s)-2-azabicyclo[2.2.1]hept-5-en-3- one (+) or (-)-lactam |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2576553A2 EP2576553A2 (de) | 2013-04-10 |
EP2576553A4 true EP2576553A4 (de) | 2013-11-20 |
Family
ID=45004819
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP11787411.5A Withdrawn EP2576553A4 (de) | 2010-05-27 | 2011-05-26 | Hochselektive asymmetrische hydroformylierung aus (1s,4r)- oder (1r,4s)-2-azabicyclo-[2.2.1-]hept-5-en-3-on(+)- oder (-)-lactam |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2576553A4 (de) |
IN (1) | IN2012CN10271A (de) |
WO (1) | WO2011150205A2 (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114716326B (zh) * | 2022-04-25 | 2024-01-05 | 岳阳昌德新材料有限公司 | 二胺化合物的制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6166022A (en) * | 1997-07-22 | 2000-12-26 | Astrazeneca Uk Limited | Compounds |
US20070049587A1 (en) * | 2005-09-01 | 2007-03-01 | Zbinden Katrin G | Factor Xa inhibitors |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6072844A (ja) * | 1983-09-29 | 1985-04-24 | Mitsubishi Petrochem Co Ltd | 極性官能基含有ホルミルノルボルナンの製造方法 |
ES2263179T3 (es) * | 1996-06-14 | 2006-12-01 | Biocryst Pharmaceuticals Inc. | Compuestos de clopentano sustituido como inhibidores de la neuraminidasa. |
JP4102022B2 (ja) | 1997-12-17 | 2008-06-18 | バイオクリスト・ファマシューティカルズ インク. | ノイラミニダーゼ阻害剤として有用な置換シクロペンタン及びシクロペンテン化合物 |
-
2011
- 2011-05-26 EP EP11787411.5A patent/EP2576553A4/de not_active Withdrawn
- 2011-05-26 IN IN10271CHN2012 patent/IN2012CN10271A/en unknown
- 2011-05-26 WO PCT/US2011/038134 patent/WO2011150205A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6166022A (en) * | 1997-07-22 | 2000-12-26 | Astrazeneca Uk Limited | Compounds |
US20070049587A1 (en) * | 2005-09-01 | 2007-03-01 | Zbinden Katrin G | Factor Xa inhibitors |
Non-Patent Citations (5)
Title |
---|
BLANCO J M ET AL: "Divergent synthesis of two precursors of 3'-homo-2'-deoxy- and 2'-homo-3'-deoxy-carbocyclic nucleosides", TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 58, no. 43, 21 October 2002 (2002-10-21), pages 8843 - 8849, XP004390194, ISSN: 0040-4020, DOI: 10.1016/S0040-4020(02)01053-0 * |
C.F. PALMER ET AL.: "Rearrangement of 2-azabicyclo[2.2.1]hept-5-en-3-ones. Synthesis of cis-3-aminocyclopentane carboxylic acid derivatives.", JOURNAL OF THE CHEMICAL SOCIETY, PERKIN TRANS 1, vol. 58, no. 8, 21 April 1992 (1992-04-21), pages 1021 - 1028, XP008165279, ISSN: 0300-922X * |
GARY M. NOONAN ET AL: "Asymmetric Hydroformylation of an Enantiomerically Pure Bicyclic Lactam: Efficient Synthesis of Functionalised Cyclopentylamines", CHEMISTRY - A EUROPEAN JOURNAL, vol. 16, no. 43, 15 November 2010 (2010-11-15), pages 12788 - 12791, XP055083083, ISSN: 0947-6539, DOI: 10.1002/chem.201002233 * |
HUANG J ET AL: "A highly enantioselective catalyst for asymmetric hydroformylation of [2.2.1]-bicyclic olefins", TETRAHEDRON LETTERS, PERGAMON, vol. 46, no. 45, 7 November 2005 (2005-11-07), pages 7831 - 7834, XP027862901, ISSN: 0040-4039, [retrieved on 20051107] * |
See also references of WO2011150205A2 * |
Also Published As
Publication number | Publication date |
---|---|
IN2012CN10271A (de) | 2015-04-10 |
WO2011150205A2 (en) | 2011-12-01 |
EP2576553A2 (de) | 2013-04-10 |
WO2011150205A3 (en) | 2012-03-29 |
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Legal Events
Date | Code | Title | Description |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
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17P | Request for examination filed |
Effective date: 20121129 |
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AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20131023 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07D 471/08 20060101AFI20131017BHEP Ipc: C07C 271/36 20060101ALI20131017BHEP Ipc: C07D 209/52 20060101ALI20131017BHEP Ipc: C07C 269/06 20060101ALI20131017BHEP |
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17Q | First examination report despatched |
Effective date: 20140711 |
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GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
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INTG | Intention to grant announced |
Effective date: 20141210 |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20150421 |