EP2408448A4 - Méthodes et compositions pour traiter l'infection par un virus de la famille des flaviviridae - Google Patents
Méthodes et compositions pour traiter l'infection par un virus de la famille des flaviviridaeInfo
- Publication number
- EP2408448A4 EP2408448A4 EP10753957A EP10753957A EP2408448A4 EP 2408448 A4 EP2408448 A4 EP 2408448A4 EP 10753957 A EP10753957 A EP 10753957A EP 10753957 A EP10753957 A EP 10753957A EP 2408448 A4 EP2408448 A4 EP 2408448A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compositions
- treating
- methods
- viral infection
- flaviviridae family
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/383,071 US9149463B2 (en) | 2007-09-18 | 2009-03-18 | Methods and compositions of treating a Flaviviridae family viral infection |
US12/383,030 US9101628B2 (en) | 2007-09-18 | 2009-03-18 | Methods and composition of treating a flaviviridae family viral infection |
PCT/US2010/027405 WO2010107742A2 (fr) | 2009-03-18 | 2010-03-16 | Méthodes et compositions pour traiter l'infection par un virus de la famille des flaviviridae |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2408448A2 EP2408448A2 (fr) | 2012-01-25 |
EP2408448A4 true EP2408448A4 (fr) | 2012-09-19 |
Family
ID=42740364
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10753957A Withdrawn EP2408448A4 (fr) | 2009-03-18 | 2010-03-16 | Méthodes et compositions pour traiter l'infection par un virus de la famille des flaviviridae |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP2408448A4 (fr) |
JP (1) | JP2012520885A (fr) |
CN (1) | CN102448457B (fr) |
WO (1) | WO2010107742A2 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103298791B (zh) * | 2010-10-20 | 2016-02-03 | 生物科学管理有限责任公司 | 病毒聚合酶抑制剂 |
HUE053282T2 (hu) | 2013-08-19 | 2021-06-28 | Univ California | Vegyületek és eljárások epilepsziás rendellenesség kezelésére |
EA032196B1 (ru) | 2013-10-03 | 2019-04-30 | Кура Онколоджи, Инк. | Ингибиторы erk и способы применения |
BR112017018297B1 (pt) | 2015-02-25 | 2023-12-05 | The Regents Of The University Of California | Uso de um agonista de receptor 5ht selecionado a partir de trazodona e lorcarserina, ou um sal farmaceuticamente aceitável dos mesmos, e uso de um agonista de receptor 5ht selecionado a partir de clemizol, um análogo de clemizol ou um sal farmaceuticamente aceitável dos mesmos |
CN105884687B (zh) * | 2016-04-14 | 2018-06-22 | 梯尔希(南京)药物研发有限公司 | 一种5-苄基苄达明的制备方法 |
CN114984030A (zh) * | 2022-06-23 | 2022-09-02 | 中国人民解放军海军军医大学 | 利巴韦林在制备抗蜱传脑炎病毒药物中的应用 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001083472A1 (fr) * | 2000-04-28 | 2001-11-08 | Acadia Pharmaceuticals, Inc. | Agonistes muscariniques |
WO2002007761A1 (fr) * | 2000-07-20 | 2002-01-31 | Merck & Co., Inc. | Inhibition de la maturation et de la replication du virus de l'hepatite c |
DE102007028521A1 (de) * | 2007-06-21 | 2008-12-24 | Merck Patent Gmbh | Indazolamidderivate |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3428634A (en) * | 1965-03-13 | 1969-02-18 | Acraf | 3-tertiary amino alkoxy-1-hydrocarbon indazoles |
AU2005219518A1 (en) * | 2004-02-27 | 2005-09-15 | F. Hoffmann-La Roche Ag | Indazole derivatives and pharmaceutical compositions containing them |
WO2006135383A2 (fr) * | 2004-08-04 | 2006-12-21 | Myriad Genetics, Inc. | Indazoles |
CN101437519A (zh) * | 2006-03-31 | 2009-05-20 | 艾博特公司 | 吲唑化合物 |
TW200927102A (en) * | 2007-09-18 | 2009-07-01 | Univ Stanford | Methods of treating a flaviviridae family viral infection, compositions for treating a flaviviridae family viral infection, and screening assays for identifying compositions for treating a flaviviridae family viral infection |
-
2010
- 2010-03-16 CN CN201080021850.XA patent/CN102448457B/zh not_active Expired - Fee Related
- 2010-03-16 EP EP10753957A patent/EP2408448A4/fr not_active Withdrawn
- 2010-03-16 WO PCT/US2010/027405 patent/WO2010107742A2/fr active Application Filing
- 2010-03-16 JP JP2012500870A patent/JP2012520885A/ja active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001083472A1 (fr) * | 2000-04-28 | 2001-11-08 | Acadia Pharmaceuticals, Inc. | Agonistes muscariniques |
WO2002007761A1 (fr) * | 2000-07-20 | 2002-01-31 | Merck & Co., Inc. | Inhibition de la maturation et de la replication du virus de l'hepatite c |
DE102007028521A1 (de) * | 2007-06-21 | 2008-12-24 | Merck Patent Gmbh | Indazolamidderivate |
Non-Patent Citations (4)
Title |
---|
ANONYMOUS, REGISTRY,, 18 December 1984 (1984-12-18) - 22 December 2009 (2009-12-22), XP007920912 * |
ANONYMOUS, REGISTRY,, 8 December 2008 (2008-12-08), XP007920913 * |
ANONYMOUS, REGISTRY,, 8 November 2004 (2004-11-08), XP007920909 * |
MANGANARO ET AL: "Activity of antiinflammatory steroidal and nonsteroidal compounds in some experimental infections. II. Activity of certain nonsteroidal antiinflammatory agents as compared with that of prednisone in murine hepatitis due to MHV3", INFLAMMATION, PLENUM PRESS, NEW YORK, NY, US, vol. Proc. Int. Symp, no. 1968, 1 January 1968 (1968-01-01), pages 67 - 71, XP008154270, ISSN: 0360-3997 * |
Also Published As
Publication number | Publication date |
---|---|
WO2010107742A2 (fr) | 2010-09-23 |
WO2010107742A3 (fr) | 2011-03-10 |
CN102448457A (zh) | 2012-05-09 |
JP2012520885A (ja) | 2012-09-10 |
EP2408448A2 (fr) | 2012-01-25 |
CN102448457B (zh) | 2015-09-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 20111018 |
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AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR |
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DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20120817 |
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17Q | First examination report despatched |
Effective date: 20130611 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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18D | Application deemed to be withdrawn |
Effective date: 20161001 |