EP2401289A4 - Altération et modulation de l'activité protéique en faisant varier la modification post-traductionnelle - Google Patents

Altération et modulation de l'activité protéique en faisant varier la modification post-traductionnelle

Info

Publication number
EP2401289A4
EP2401289A4 EP10746882A EP10746882A EP2401289A4 EP 2401289 A4 EP2401289 A4 EP 2401289A4 EP 10746882 A EP10746882 A EP 10746882A EP 10746882 A EP10746882 A EP 10746882A EP 2401289 A4 EP2401289 A4 EP 2401289A4
Authority
EP
European Patent Office
Prior art keywords
alteration
modulation
protein activity
translational modification
varying post
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP10746882A
Other languages
German (de)
English (en)
Other versions
EP2401289A1 (fr
Inventor
David N Thompson
David W Reed
Vicki S Thompson
Jeffrey A Lacey
William A Apel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Battelle Energy Alliance LLC
Original Assignee
Battelle Energy Alliance LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/380,450 external-priority patent/US9234228B2/en
Priority claimed from US12/655,993 external-priority patent/US8969033B2/en
Application filed by Battelle Energy Alliance LLC filed Critical Battelle Energy Alliance LLC
Publication of EP2401289A1 publication Critical patent/EP2401289A1/fr
Publication of EP2401289A4 publication Critical patent/EP2401289A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2477—Hemicellulases not provided in a preceding group
    • C12N9/248—Xylanases

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP10746882A 2009-02-26 2010-02-26 Altération et modulation de l'activité protéique en faisant varier la modification post-traductionnelle Withdrawn EP2401289A4 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12/380,450 US9234228B2 (en) 2008-02-27 2009-02-26 Thermophilic and thermoacidophilic glycosylation genes and enzymes from Alicyclobacillus acidocaldarius and related organisms, methods
PCT/US2009/035307 WO2010051049A2 (fr) 2008-02-27 2009-02-26 Gènes et enzymes de glycosylation thermophiles et thermoacidophiles provenant d'alicyclobacillus acidocaldarius et d'organismes apparentés, et procédés
US12/655,993 US8969033B2 (en) 2005-11-02 2010-01-12 Alteration and modulation of protein activity by varying post-translational modification
PCT/US2010/025521 WO2010099394A1 (fr) 2009-02-26 2010-02-26 Altération et modulation de l'activité protéique en faisant varier la modification post-traductionnelle alteration and modulation of protein activity by varying post-translational modification

Publications (2)

Publication Number Publication Date
EP2401289A1 EP2401289A1 (fr) 2012-01-04
EP2401289A4 true EP2401289A4 (fr) 2012-10-03

Family

ID=42665924

Family Applications (1)

Application Number Title Priority Date Filing Date
EP10746882A Withdrawn EP2401289A4 (fr) 2009-02-26 2010-02-26 Altération et modulation de l'activité protéique en faisant varier la modification post-traductionnelle

Country Status (6)

Country Link
EP (1) EP2401289A4 (fr)
CN (1) CN102317309A (fr)
AU (1) AU2010217847A1 (fr)
BR (1) BRPI1008486A2 (fr)
CA (1) CA2752175A1 (fr)
WO (1) WO2010099394A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160130324A1 (en) 2014-10-31 2016-05-12 Shire Human Genetic Therapies, Inc. C1 Inhibitor Fusion Proteins and Uses Thereof
WO2017087882A1 (fr) 2015-11-19 2017-05-26 Shire Human Genetic Therapies, Inc. Inhibiteur de la c1 estérase humaine recombinante et ses utilisations
CN110506111A (zh) * 2016-11-28 2019-11-26 希-莱科塔有限公司 海藻糖磷酸化酶
CN108192906B (zh) * 2017-12-28 2021-05-11 江苏世邦生物工程科技有限公司 一种含有低温脂肪酶基因的工程菌及其构建方法和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070099282A1 (en) * 2005-11-02 2007-05-03 Battelle Energy Alliance, Llc Enzyme and methodology for the treatment of a biomass

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006078821A2 (fr) * 2005-01-21 2006-07-27 Invitrogen Corporation Produits et procedes de synthese de biomolecules in vitro
WO2010051049A2 (fr) * 2008-02-27 2010-05-06 Battelle Energy Alliance, Llc Gènes et enzymes de glycosylation thermophiles et thermoacidophiles provenant d'alicyclobacillus acidocaldarius et d'organismes apparentés, et procédés

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070099282A1 (en) * 2005-11-02 2007-05-03 Battelle Energy Alliance, Llc Enzyme and methodology for the treatment of a biomass

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BIRGIT SCHWERMANN ET AL: "Purification, Properties and Structural Aspects of a Thermoacidophilic alpha-Amylase from Alicyclobacillus Acidocaldarius Atcc 27009. Insight into Acidostability of Proteins", EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 226, no. 3, 1 December 1994 (1994-12-01), pages 981 - 991, XP055007469, ISSN: 0014-2956, DOI: 10.1111/j.1432-1033.1994.00981.x *
ECKERT K ET AL: "A thermoacidophilic endoglucanase (CelB) from Alicyclobacillus acidocaldarius displays high sequence similarity to arabinofuranosidases belonging to family 51 of glycoside hydrolases", EUROPEAN JOURNAL OF BIOCHEMISTRY, BLACKWELL PUBLISHING, BERLIN, DE, vol. 270, no. 17, 1 September 2003 (2003-09-01), pages 3593 - 3602, XP002297030, ISSN: 0014-2956, DOI: 10.1046/J.1432-1033.2003.03744.X *
See also references of WO2010099394A1 *

Also Published As

Publication number Publication date
AU2010217847A1 (en) 2011-10-27
BRPI1008486A2 (pt) 2018-01-16
WO2010099394A1 (fr) 2010-09-02
WO2010099394A9 (fr) 2011-10-13
CA2752175A1 (fr) 2010-09-02
EP2401289A1 (fr) 2012-01-04
CN102317309A (zh) 2012-01-11

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