EP2318078A2 - User friendly inhalation device - Google Patents

User friendly inhalation device

Info

Publication number
EP2318078A2
EP2318078A2 EP09762775A EP09762775A EP2318078A2 EP 2318078 A2 EP2318078 A2 EP 2318078A2 EP 09762775 A EP09762775 A EP 09762775A EP 09762775 A EP09762775 A EP 09762775A EP 2318078 A2 EP2318078 A2 EP 2318078A2
Authority
EP
European Patent Office
Prior art keywords
inhalation
capsule
shaft
chamber
needle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09762775A
Other languages
German (de)
English (en)
French (fr)
Inventor
Bilgic Mahmut
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SIMA PATENT VE LISANSLAMA HIZMETLERI LTDSTI
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP2318078A2 publication Critical patent/EP2318078A2/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A61M15/0026—Hinged caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0041—Details of the piercing or cutting means with movable piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/586—Ergonomic details therefor, e.g. specific ergonomics for left or right-handed users

Definitions

  • the present invention relates to an inhalation device that has a mechanism providing a capsule perforation process which needs a specific force, to be done in every condition in order to facilitate inhalation of dry powder drug, which is kept in a penetrable capsule.
  • Pharmaceuticals which can be inhaled are generally used to treat diseases in bronchial or pulmonary region such as asthma or chronic bronchitis.
  • breath activating devices wherein the delivery of dry powder drug to the air passage is provided.
  • dry powder inhalator devices operate via loading of capsule comprising dry powder drug into the device, perforation of the capsule via compression or with needles and delivering dry powder to pulmonary region via breathing.
  • beta-2 -agonists corticosteroids
  • antibiotics antimuscarinic, antiallergic or anticholinergic agents for treating of pulmonary diseases such as asthma, chronic obstructive pulmonary disease.
  • Mechanism according to the invention provides perforation of dry powder capsules with needles and delivery of dry powder drug particles via the pressure that is created via breathing, from the capsule to the lung.
  • perforation of the drug capsules is required to be done via needles by getting in and out of the capsule or via other techniques.
  • breaking or perforation process of capsule comprising the dry powder drug that is present in device
  • the patient population wherein the device comprising the mechanism is used includes the children and elderly patients.
  • perforation process is mechanically made via compression of capsule with hands and fingers. These known techniques are designed in such a way that the compression force is standart for all the patients including elderly and children. Adults can easily perform perforation process of capsule, but children and elderly may not be able to apply enough force. As a result, the needles cannot perforate the capsule sufficiently; and adequate drug dose fails to reach to pulmonary region.
  • the present invention relates to an inhalation device that has a mechanism providing a capsule perforation process which needs a specific force, to be done in every condition in order to facilitate inhalation of dry powder drug, which is kept in a penetrable capsule.
  • Needle compression force in the invented device mechanism is provided via opening-closing movement of collapsible inhalation shaft.
  • the applied force is low, in and out movement of needles into the capsule becomes a standard motion, since the mechanism of the present invention depends on lever mechanism.
  • the only essential step during usage of this device is not to forget to load the capsule. Once the capsule is loaded to the device, inhalation cannot be done until the inhalation shaft is closed. Once inhalation shaft is closed, needles get in and out of capsule and the device is made ready for inhalation by patients.
  • the same mechanism works automatically again while the inhalation shaft is opened in order to dispose empty capsule; it enables the capsule to be dislodged and to be discharged easily.
  • Figure 1 is an explosive view of the device according to the invention
  • Figure 2 is side view of the device according to the invention are given
  • the mechanism according to the invention consists of eleven components that are listed below and depicted in figure- 1 and figure-2 in detail:
  • the proposed mechanism is encapsulated within in two main caps; top and bottom cover in order to maintain the mechanism decent while being carried in a pocket and to facilitate handheld.
  • Exterior surface of the inhalation shaft (4) is designed compatible to the mouth shape for sucking and it is related to Inhalation Chamber (9) together with Filter that is present within the inhalation shaft. As the inhalation shaft (4) opens; the inhalation chamber (9) is opened simultaneously.
  • the knuckle Pin (10) keeps these three groups together and enables (allows) the caps to be open.
  • the top cover is opened in order to load the capsule.
  • Inhalation shaft is uplifted, until the capsule chamber can be seen.
  • Drug capsule loaded into the capsule chamber.
  • two toothed tracks that are present on the inhalation shaft, drive the toothed rod. Toothed rod pushes needle and spring holder in order to pierce the capsule.
  • the toothed rod disengages as the inhalation shaft is completely closed. Releasing of the spring at the opposite direction removes the needle and the spring holder back, sets up the mechanism and makes the dry powder drug ready for inhalation.
  • inhalation shaft is opened and simultaneously, system starts to work again. Needles get in and out of empty capsule once again. This process dislodges empty capsule. Empty capsule is taken easily from chamber and discharged.
  • the device having the mechanism according to the invention is preferably used for inhalation of drugs such as beta-2agonists, corticosteroids, anti-cholinergic agents, antimuscarinics, antiallergics and antibiotics, for the treatment of pulmonary diseases or local treatment of pulmonary diseases like asthma and chronic obstructive pulmonary diseases.
  • drugs such as beta-2agonists, corticosteroids, anti-cholinergic agents, antimuscarinics, antiallergics and antibiotics, for the treatment of pulmonary diseases or local treatment of pulmonary diseases like asthma and chronic obstructive pulmonary diseases.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
EP09762775A 2008-05-16 2009-05-15 User friendly inhalation device Withdrawn EP2318078A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2008/03522A TR200803522A1 (tr) 2008-05-16 2008-05-16 Kolay kullanımlı inhalasyon cihazı.
PCT/TR2009/000062 WO2009151408A2 (en) 2008-05-16 2009-05-15 User friendly inhalation device

Publications (1)

Publication Number Publication Date
EP2318078A2 true EP2318078A2 (en) 2011-05-11

Family

ID=41280449

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09762775A Withdrawn EP2318078A2 (en) 2008-05-16 2009-05-15 User friendly inhalation device

Country Status (3)

Country Link
EP (1) EP2318078A2 (tr)
TR (1) TR200803522A1 (tr)
WO (1) WO2009151408A2 (tr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2534958A1 (en) 2007-12-14 2012-12-19 AeroDesigns, Inc Delivering aerosolizable food products
WO2011093809A2 (en) 2010-01-28 2011-08-04 Mahmut Bilgic Dry powder pharmaceutical composition comprising tiotropium and ciclesonide
WO2011093810A2 (en) 2010-01-28 2011-08-04 Bilgic Mahmut Dry powder pharmaceutical composition comprising tiotropium and mometasone
EP2528600B1 (en) 2010-01-28 2016-06-29 Mahmut Bilgic Dry powder pharmaceutical composition comprising tiotropium and fluticasone
WO2011093814A2 (en) 2010-01-29 2011-08-04 Mahmut Bilgic A pharmaceutical combination comprising formoterol and ciclesonide
WO2011149436A1 (en) * 2010-05-28 2011-12-01 Mahmut Bilgic Advanced dry powder inhaler
TR201008226A2 (tr) * 2010-10-07 2012-04-24 Bi̇lgi̇ç Mahmut Kapsül içeren bir inhalasyon cihazı.
GB201020638D0 (en) 2010-12-06 2011-01-19 Liconsa Laboratorios Sa Inhalator
CN102553040B (zh) * 2010-12-17 2014-07-02 陈庆堂 滤出药粉吸入器
ITMO20110051A1 (it) * 2011-03-04 2012-09-05 Ano & C Inalatore portatile di sostanze in polvere

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1182779A (en) 1966-09-17 1970-03-04 Fisons Pharmaceuticals Ltd Inhalation Device
DE602004014909D1 (de) 2003-03-20 2008-08-21 Galephar M F Verbessertes trockenpulver-inhalationssystem
GB2407042B (en) * 2003-10-17 2007-10-24 Vectura Ltd Inhaler
GB0410712D0 (en) 2004-05-13 2004-06-16 Novartis Ag Organic compounds
EA010922B1 (ru) * 2004-11-10 2008-12-30 Сипла Лимитед Ингалятор
DE102006006647B3 (de) 2006-02-14 2007-01-18 Braunform Gmbh Vorrichtung zum Inhalieren eines in einer Kapsel sich befindenden Pulvers
DE102006017699A1 (de) * 2006-04-15 2007-10-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
DE102007036411A1 (de) * 2007-07-20 2009-02-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
None *
See also references of WO2009151408A2 *

Also Published As

Publication number Publication date
WO2009151408A2 (en) 2009-12-17
TR200803522A1 (tr) 2009-12-21
WO2009151408A3 (en) 2010-02-04

Similar Documents

Publication Publication Date Title
WO2009151408A2 (en) User friendly inhalation device
JP6284884B2 (ja) 吸入装置
US10549052B2 (en) Nasal delivery device
KR101529354B1 (ko) 에어로졸화가능 제약 제제의 저장기
EP2432536B1 (en) Rotary cassette system for dry powder inhaler
AU749292B2 (en) Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
NO334854B1 (no) Inhalatoranordning.
JP6929871B2 (ja) 吸気同期式の流体吐出装置
CN101547717A (zh) 药盒
JP2024057017A (ja) 粉末薬剤をカプセルから放出するためにカプセルに穴を開けるための装置および方法
WO2014204417A1 (en) Inhalation device comprising a flexible plate
EP3138601B1 (en) Dry powder inhaler
JP2022517953A (ja) 経鼻薬品送達デバイス
JP6936249B2 (ja) 吸気同期式の流体吐出装置
WO2009139731A1 (en) A mechanism including a blister strip
US9339614B2 (en) Filtering powder medicament inhaler and application
CA2903980C (en) Method and device for clamping a blister within a dry powder inhaler
WO2009139732A1 (en) Dry powder inhaler
WO2006033585A1 (en) Powder inhaler, system for opening and emptying capsules
CN200960345Y (zh) 弹扎式干粉吸入装置
CN106031810A (zh) 吸粉器及连接于该吸粉器的吸粉器本体上的药匣组件
WO2009139733A1 (en) Dry powder inhalation device
CN109847158B (zh) 一种胶囊型干粉吸入器
CN104984449B (zh) 一种可翻转打开的胶囊干粉吸入装置
RU2369411C2 (ru) Порошковый ингалятор

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20101207

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA RS

DAX Request for extension of the european patent (deleted)
RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: BILGIC, MAHMUT

RIN1 Information on inventor provided before grant (corrected)

Inventor name: BILGIC, MAHMUT

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: SIMA PATENT VE LISANSLAMA HIZMETLERI LTD.STI.

RIN1 Information on inventor provided before grant (corrected)

Inventor name: SIMA PATENT VE LISANSLAMA HIZMETLERI LTD.STI.

17Q First examination report despatched

Effective date: 20170222

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20170705