EP2291118A2 - Dispositif de mesure et procédé de détermination de paramètres de tissus - Google Patents

Dispositif de mesure et procédé de détermination de paramètres de tissus

Info

Publication number
EP2291118A2
EP2291118A2 EP09757263A EP09757263A EP2291118A2 EP 2291118 A2 EP2291118 A2 EP 2291118A2 EP 09757263 A EP09757263 A EP 09757263A EP 09757263 A EP09757263 A EP 09757263A EP 2291118 A2 EP2291118 A2 EP 2291118A2
Authority
EP
European Patent Office
Prior art keywords
measuring
tissue
coaxial line
tip
control device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09757263A
Other languages
German (de)
English (en)
Inventor
Martin Leibfritz
Christian Evers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rohde and Schwarz GmbH and Co KG
Original Assignee
Rohde and Schwarz GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rohde and Schwarz GmbH and Co KG filed Critical Rohde and Schwarz GmbH and Co KG
Publication of EP2291118A2 publication Critical patent/EP2291118A2/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053Measuring electrical impedance or conductance of a portion of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053Measuring electrical impedance or conductance of a portion of the body
    • A61B5/0538Measuring electrical impedance or conductance of a portion of the body invasively, e.g. using a catheter
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R27/00Arrangements for measuring resistance, reactance, impedance, or electric characteristics derived therefrom
    • G01R27/02Measuring real or complex resistance, reactance, impedance, or other two-pole characteristics derived therefrom, e.g. time constant
    • G01R27/26Measuring inductance or capacitance; Measuring quality factor, e.g. by using the resonance method; Measuring loss factor; Measuring dielectric constants ; Measuring impedance or related variables
    • G01R27/2617Measuring dielectric properties, e.g. constants
    • G01R27/2635Sample holders, electrodes or excitation arrangements, e.g. sensors or measuring cells
    • G01R27/2676Probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments

Definitions

  • the invention relates to a measuring device and a method for determining tissue parameters.
  • biopsies are performed to determine tissue parameters.
  • a biopsy is always associated with tissue damage.
  • the exact location for making a biopsy can not be reliably determined.
  • WO 03/060462 A2 shows a device for measuring electrical parameters of a tissue.
  • a sensor is placed on a tissue.
  • the tissue is supplied with an electrical signal.
  • a resulting signal is measured.
  • Information about the tissue is obtained from the transmitted signal and the received signal.
  • the disadvantage here is that removal of the sensor and the subsequent performance of further investigation is necessary to obtain more accurate information. An exact positioning in the same place of the tissue is not possible. This results in a low accuracy.
  • WO 2005/009200 A2 shows a device which, by means of a sensor integrated in the tip of a special biopsy needle, detects electrical properties of the tissue measures. After completion of the measurement, a tissue sample can be obtained by means of the biopsy needle. However, the tissue sample is recovered laterally on the biopsy needle. Due to the lack of conformity of the measuring position and the biopsy position only a low accuracy is achieved.
  • WO 2006/103665 A2 shows a sensor for
  • Tissue characterization involving a resonator.
  • the resonator is brought into contact with the tissue and detuned by this. From the detuning is concluded on the tissue properties.
  • the disadvantage here is that the resonator is connected only via a single supply line. Thus, due to interference only low accuracy is guaranteed.
  • the resonator structures shown here only allow a measurement of low accuracy.
  • the three-dimensional design of the resonator causes interference, which further reduces the accuracy of the measurement.
  • no removal of tissue samples is possible here.
  • the invention is based on the object to provide an apparatus and a method for the determination of tissue parameters with low load of the patient and high parameter accuracy.
  • a measuring device has a control device, a measuring signal transmitter, a measuring signal receiver and a measuring tip.
  • the measuring tip includes at least one coaxial line.
  • the control device controls the measuring signal transmitter in such a way that it sends a measuring signal by means of the coaxial line into a specific location of a tissue.
  • the measurement signal is scattered by the tissue.
  • the control device controls the measurement signal receiver such that it receives the scattered measurement signal.
  • the control device evaluates the received measurement signal.
  • the measuring tip is designed such that a tissue sample can be taken with it at the specific location of the tissue. Thus, a gentle electrical measurement can be made before a tissue sample is taken. The number of tissue samples loading the patient is thus reduced. Furthermore, the number of tissue samples to be examined is reduced.
  • the measuring tip preferably includes a biopsy needle.
  • the coaxial line is preferably arranged within the biopsy needle. So conventional biopsy needles can be used. Furthermore, the use of very thin, flexible, cheaper coaxial cables is possible.
  • the coaxial line is advantageously movable within the biopsy needle.
  • the coaxial line is preferably retracted at a location where a tissue sample is to be removed by at least a length of the tissue sample.
  • the tissue sample preferably penetrates into the biopsy needle and is preferably fixed by the latter. So a tissue sample can be obtained from just the location of the electrical measurement. The exact length of the tissue sample can be determined so very accurately. This reduces the burden on the patient and increases the accuracy of tissue parameter determination.
  • the coaxial line alternatively has sharp edges.
  • the coaxial line advantageously has a fixed shape.
  • the coaxial line can be inserted into tissue without a supporting biopsy needle. This reduces the effort of production and simplifies handling.
  • the coaxial line preferably includes an inner conductor, an outer conductor and a dielectric.
  • the dielectric is preferably movable.
  • the dielectric is preferably retracted at a location where a tissue sample is to be removed by at least a length of the tissue sample.
  • the tissue sample advantageously penetrates into a space between the outer conductor and the
  • Inner conductor and is fixed by these. Thus, despite the ease of manufacture and handling a tissue sample can be obtained exactly at the site of the electrical measurement.
  • the measuring tip alternatively contains two
  • the measuring signal transmitter preferably transmits the measuring signal by means of a first coaxial line into the tissue.
  • the measuring signal receiver preferably receives the measuring signal by means of a second coaxial line. This prevents electromagnetic interference in the measuring line. The accuracy of the electrical measurement can thus be improved.
  • An alternative measuring device includes a control device, a measuring signal transmitter, a measuring signal receiver and a measuring tip.
  • the measuring tip includes at least two coaxial cables and a resonator circuit.
  • a first coaxial line is connected to the resonator circuit and the measurement signal transmitter.
  • a second coaxial line is connected to the resonator circuit and the measuring signal receiver.
  • the control device controls the measuring signal transmitter in such a way that it transmits a measuring signal to the resonator circuit by means of the first coaxial line.
  • the control device controls the measuring signal receiver in such a way that it receives the scattered measuring signal from the resonator circuit by means of the second coaxial line.
  • the resonant characteristics of the resonator circuit are affected by nearby tissue.
  • the control device evaluates the received measurement signal. So a very accurate electrical measurement can be performed.
  • the resonator circuit preferably consists of a printed circuit board with at least one strip conductor arranged thereon. A simple production of the resonator circuit is possible.
  • a first strip conductor is preferably conductively connected to the first coaxial line.
  • a second strip conductor is preferably conductively connected to the second coaxial line.
  • a third strip conductor is preferably conductively connected to the third coaxial line.
  • Strip conductor is preferably arranged between the first strip conductor and the second strip conductor.
  • the third stripline is advantageously capacitive with the first stripline and the second Strip conductor connected.
  • the third strip conductor is preferably annular or straight.
  • the third stripline advantageously determines the resonant wavelength of the resonator circuit.
  • the length of the third strip conductor is advantageously 1/4 to H, preferably H of the resonant wavelength of the resonator circuit.
  • the tissue to be examined is preferably arranged in the vicinity of the third strip conductor. So can a strong
  • the measuring tip is preferably designed such that with it a tissue sample at the specific location of the tissue can be removed.
  • a tissue sample can be obtained from exactly the place of measurement.
  • FIG. 1 shows a first embodiment of a measuring device according to the invention
  • Fig. 2 is a detail view of a second
  • Fig. 3 is a first detail view of a third
  • Fig. 4 is a second detail view of the third embodiment of an inventive
  • Fig. 5 is a third detail view of the third
  • Fig. 6 is a first sectional view of a fourth
  • Fig. 7 is a second sectional view of the fourth
  • Fig. 8 is a third sectional view of the fourth
  • Fig. 10 is a detail view of a sixth
  • Fig. 12 is a detail view of an eighth embodiment of an inventive
  • Fig. 13 is a detail view of a ninth
  • Fig. 14 is a flowchart of a first
  • Fig. 15 is a flowchart of a second
  • FIG. 1 a first embodiment of a measuring device according to the invention is shown.
  • a measuring tip 1 is connected by means of a connecting line 6 with a housing 5.
  • the housing 5 includes a control device 4, a measuring signal transmitter 2 and a measuring signal receiver 3.
  • the control device 4 is connected to the measuring signal transmitter 2 and the measuring signal receiver 3.
  • the control device 4 controls both the measuring signal transmitter 2 and the measuring signal receiver 3.
  • the measuring tip 1 is brought into contact with a tissue to be examined in order to carry out a measurement. This can be done by putting on as well as by piercing.
  • the control device 4 controls the measuring signal transmitter 2 in such a way that it sends a measuring signal into the tissue by means of the measuring tip.
  • the measurement signal is scattered by the tissue.
  • the control device 4 controls the measuring signal receiver 3 such that it receives the scattered measuring signal.
  • the control device 4 evaluates the scattered measurement signal. In doing so, she notes abnormalities of the tissue. Abnormalities are, for example, tumorous tissue changes. If an abnormality has been detected in the tissue at the site of the measurement, a tissue sample is taken by means of the measuring tip for further examinations. In this case, the removed tissue largely coincides with the tissue, which was acted upon by the measurement signal.
  • FIG. 2 shows a detailed view of a second embodiment of a measuring device according to the invention.
  • the front End of a measuring tip 1 according to the invention shown.
  • This front end consists of a coaxial line 7, one end of which is open.
  • the coaxial line 7 includes an inner conductor 12, a dielectric 13, an outer conductor 11 and an insulation 10.
  • the dielectric 13 is shown for the sake of clarity transparent.
  • the dielectric 13 fills the entire space between the inner conductor 12 and the outer conductor 11.
  • the insulation 10 encloses the outside of the outer conductor 11 completely.
  • the open end of the coaxial line 7 is brought into contact with the tissue to be examined.
  • positioning near the tissue to be examined is possible.
  • the tissue is acted upon by means of the coaxial line 7 with a measurement signal.
  • the measurement signal scattered by the tissue is likewise received and forwarded by means of the coaxial line 7.
  • the isolation is for biological compatibility. A body reaction to the material of the coaxial line is thus avoided.
  • this embodiment is only suitable for exposed tissue, since due to the blunt end a penetration into tissue is not, or very difficult is possible.
  • FIG. 3 shows a first detail view of a third exemplary embodiment of a measuring device according to the invention. This embodiment largely corresponds to the embodiment shown in FIG.
  • the end of the coaxial line 8 is but not blunt, but has an acute angle.
  • the outer conductor 21 corresponds to the outer conductor 11 from FIG. 2.
  • the dielectric 23 corresponds to the dielectric 13 from FIG. 2.
  • the inner conductor 22 corresponds to the inner conductor 12 from FIG. 2.
  • the insulation 10 ensures easy insertion.
  • the insulation 10 is not necessarily necessary. In insensitive tissue types can be dispensed with. Even with the use of materials for the coaxial line, which cause only small reactions insulation is not necessary.
  • a biopsy needle 30 is formed by a hollow metal tube and has an acute angle at its end. The edges of the end are sharp. A piercing of the biopsy needle 30 in tissue is possible.
  • the inner diameter of the biopsy needle 30 is slightly larger than the outer diameter of the insulation 10 of FIG. 3.
  • FIG. 5 shows a third detail view of the third exemplary embodiment of a measuring device according to the invention.
  • the coaxial line 8 of FIG. 3 is inserted into the biopsy needle 30.
  • the ends of the coaxial line 8 and the biopsy needle 30 terminate flush.
  • the biopsy needle 30 gives the coaxial line 8 the necessary stability and the end of the coaxial line 8 the necessary sharpness to be able to be inserted into tissue can.
  • the biopsy needle 30 with the coaxial line 8 located therein is inserted into the tissue.
  • a placement on already exposed tissue is possible.
  • an electrical measurement is carried out by means of the coaxial line 8.
  • the coaxial line 8 is retracted by the length of a desired tissue sample within the biopsy needle 30.
  • the biopsy needle 30 is inserted further into the tissue by the desired length of the tissue sample.
  • the tissue sample penetrates into the biopsy needle 30 and is fixed by this.
  • the measuring tip with the tissue sample is pulled out of the tissue. By pushing back the coaxial line 8, the tissue sample is pushed out of the biopsy needle.
  • FIG. 6 shows a first detailed view of a fourth exemplary embodiment of a measuring device according to the invention.
  • the exemplary embodiment shows a measuring tip according to the invention in a sectional representation. This measuring tip only contains a stable
  • the coaxial line 81 consists of an outer conductor 21, a dielectric 80 and an inner conductor 22.
  • the outer conductor 21 is designed to be more stable than in a conventional coaxial line. So The outer conductor 21 stabilizes the entire coaxial line 81 and thus ensures that no further stabilizing components are needed.
  • a stable embodiment of the inner conductor 22 is optionally possible.
  • the dielectric 80 is movable relative to the outer conductor 21 and inner conductor 22. For better clarity, the insulation surrounding the outer conductor has not been shown.
  • the measuring tip In order to determine tissue parameters, the measuring tip is inserted into the tissue. If the front end of the measuring tip has reached a point to be assessed within the tissue, a measurement of the electrical parameters of the tissue is carried out. For this purpose, the tissue is acted upon by the coaxial line 81 with a measurement signal. The tissue scatters the measurement signal. The scattered measurement signal is likewise received by the coaxial line 81 and passed on for further processing.
  • tissue parameters have been determined which make a biopsy necessary, a tissue sample is taken. This will be discussed in more detail with reference to FIGS. 7-8.
  • FIG. 7 shows a second detail view of the fourth exemplary embodiment of a measuring device according to the invention. This representation largely corresponds to FIG. 6. However, the dielectric 80 is here opposite to the outer conductor 21 and the inner conductor 22 retracted relative to the front end of the measuring tip.
  • the measuring tip is inserted further into the tissue by at least the length of the tissue sample to be taken.
  • the tissue penetrates into the space between the outer conductor and the inner conductor.
  • the retraction of the dielectric 80 may occur simultaneously with the further penetration of the probe tip into the tissue.
  • 8 shows a third detail view of the fourth exemplary embodiment of a measuring device according to the invention.
  • the measuring tip is shown with a taken tissue sample 82.
  • the tissue sample 82 is thereby of the tissue sample 82.
  • the dielectric 80 In order to remove the tissue sample 82 from the measuring tip, after retracting the measuring tip from the tissue, the dielectric 80 is pushed back to its original position, shown in FIG. 6, with respect to the outer conductor 21 and the inner conductor 22. In this case, the tissue sample 82 is ejected at the front end of the measuring tip.
  • FIG. 9 shows a detailed view of a fifth exemplary embodiment of a measuring device according to the invention.
  • the measuring tip includes two coaxial lines 48, 49.
  • the coaxial lines each have an outer conductor 40, 41, a dielectric 46, 47 and an inner conductor 44, 45.
  • the dielectric 46, 47 was thereby transparent shown.
  • the front end of the coaxial lines 48, 49 is dull.
  • This measuring tip corresponds to the measuring tip shown in FIG. That a deep penetration of the measuring tip into tissue is not possible. Only a placement on a tissue and the removal of a tissue sample from the tissue surface is possible.
  • a measurement signal is sent through the first coaxial line 48 into the tissue.
  • the scattered measurement signal is conducted via the second coaxial line 49 for further processing.
  • transmission measurements can also be carried out.
  • FIG. 10 shows a detailed view of a sixth exemplary embodiment of a measuring device according to the invention. This illustration also shows the front end of an alternative probe tip.
  • the measuring tip includes two coaxial lines 58, 59.
  • Coaxial lines 58, 59 include an outer conductor 50, 51, a dielectric 56, 57, an inner conductor 54, 55, and an insulation 52, 53.
  • the front ends of the coaxial lines 58, 59 are made bevelled and form a common tip, which has an acute angle.
  • the two coaxial lines 58, 59 are analogous to those in FIG Fig. 4 illustrated embodiment introduced into a biopsy needle.
  • the biopsy needle is according to the shape of the two coaxial lines 58, 59 against a conventional biopsy needle of oval or constricted cross-section.
  • FIG. 11 shows a detailed view of a seventh exemplary embodiment of a measuring device according to the invention. The one shown here
  • Embodiment is a modification of the embodiment shown in Fig. 9.
  • a circuit board 60 is mounted in front of the open ends of the coaxial lines 95, 96.
  • the printed circuit board 60 is shown transparent for the sake of clarity.
  • the further embodiment of the printed circuit board 60 and its function will be explained in more detail with reference to FIGS. 12-13.
  • FIG. 12 shows a detailed view of an eighth exemplary embodiment of a measuring device according to the invention.
  • a first alternative of the printed circuit board 60 of FIG. 11 is shown.
  • the circuit board 60 a has on its side remote from the coaxial lines 48, 49 side a resonator circuit 67 consisting of three strip lines 61, 62, 63 on.
  • the first two strip lines 62, 63 have only a small length.
  • the third stripline 61 has a much greater length.
  • the strip lines 61, 62, 63 are arranged in a line substantially centrally on the circuit board 60 a .
  • the first two strip lines 62, 63 are connected to the inner conductors 44, 45. This connection is made by means of a via through the circuit board 60 a .
  • the third strip line 61 is non-conducting connected to the inner conductors 44, 45 or the remaining strip lines 62, 63. However, the distances between the third strip line 61 and the remaining strip lines 62, 63 are small. A capacitive coupling occurs.
  • the third stripline 61 forms a resonator.
  • the resonance wavelength of the resonator in the exemplary embodiment is approximately twice its length. It is thus a ⁇ / 2 resonator. The exact resonance wavelength depends on the environment of the
  • Resonator Particularly accurate measurements are achieved by a conductive coating on the back of the circuit board 60 a .
  • the rear-side coating has recesses at the passage points of the inner conductors 44, 45 and the dielectric 46, 47.
  • the recesses preferably have at least the diameter of the coaxial lines 95, 96.
  • the circuit board is brought into contact with the tissue to be examined. Alternatively, it is sufficient to bring the circuit board in the vicinity of the area to be examined. In this case, the tissue to be examined is brought into the vicinity of the resonator or in contact with the resonator. As a result, the properties of the environment of the resonator are changed. This affects the resonance wavelength of the resonator.
  • the first coaxial line 95 the resonator is subjected to a measurement signal.
  • the second coaxial line 96 passed the influenced by the resonator measurement signal for further processing. Thus, the exact resonance frequency, losses occurring and the shape of the resonance curve of the resonator can be determined. Based on the determined parameters, electrical tissue parameters are determined.
  • FIG. 13 shows a detailed view of a ninth exemplary embodiment of a measuring device according to the invention.
  • the strip lines 64, 65, 66 form the resonator circuit 68.
  • the third strip line 66 is designed here in a circular manner.
  • the remaining strip lines 64, 65 correspond to the remaining strip lines 62, 63 from FIG. 12.
  • the third strip line 66 also acts here as a resonator.
  • the circumference of the circular strip line 66 is approximately half the resonance wavelength of the resonator. Again, the exact resonant frequency of the resonator is determined by the surrounding tissue.
  • a removal of a tissue sample is also possible with a measuring tip according to this embodiment.
  • the circuit board 60 is made very small.
  • the coaxial lines are arranged analogously to the embodiment shown in FIG. 5 in a biopsy needle. The removal takes place as shown there after removal of the coaxial lines with the circuit board 60th
  • Fig. 14 shows a first embodiment of the method according to the invention.
  • a coaxial line open at one end is inserted into a biopsy needle. Together they form a measuring tip.
  • the Probe tip inserted into a tissue, the tip of the biopsy needle and thus also the end of the coaxial line to come to a place to be examined within the area to lie.
  • a measurement of electrical parameters of the tissue is made.
  • the tissue is subjected to a measurement signal.
  • the measurement signal is scattered by the tissue.
  • the scattered measurement signal is received.
  • the received measurement signal is evaluated.
  • the coaxial line is withdrawn from the biopsy needle at least by the length of a tissue sample to be taken.
  • the measuring tip is inserted further into the tissue at least by the length of the tissue sample to be taken. This tissue penetrates into the biopsy needle and is fixed by this.
  • the measuring tip together with the tissue sample is pulled out of the tissue.
  • a second exemplary embodiment of the method according to the invention shown in FIG. 15 may alternatively be used.
  • a tissue to be examined is contacted with a measuring tip.
  • the measuring tip contains a resonator.
  • the resonant properties of the resonator are determined by the Tissue influences. That is, the resonance wavelength of the resonator changes depending on the properties of the tissue.
  • a resonance measurement is performed.
  • the resonator is successively acted upon by a plurality of measuring signals of different frequencies.
  • the resulting signal of the resonator is measured and forwarded for evaluation.
  • a third step 92 by comparing the transmitted measurement signal and the signal received by the resonator, the
  • Resonance wavelength of the resonator determined. From the resonance wavelength is on the properties of the tissue, especially in breast cancer or prostate cancer, concluded. The determination of the electrical parameters can be done using a network analyzer.
  • the tissue to be examined is dead or living human, animal or plant tissue. In particular, it can be concluded from the tissue parameters on the presence of tumorous changes of the tissue.
  • the invention is not limited to the illustrated embodiment. Thus, different types of tissue can be examined. Also an application for

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  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Un dispositif de mesure comprend un dispositif de commande (4), un émetteur de signal de mesure (2), un récepteur de signal de mesure (3) et une pointe de mesure (1), laquelle (1) présente au moins un câble coaxial. Le dispositif de commande (4) commande l'émetteur de signal de mesure (2) de façon qu'il émette un signal de mesure en un point déterminé d'un tissu, au moyen du câble coaxial. Le signal de mesure est diffusé par le tissu. Le dispositif de commande (4) commande le récepteur de signal de mesure (3) de telle façon qu'il reçoive le signal de mesure diffusé. Le dispositif de commande (4) évalue le signal de mesure reçu. La pointe de mesure (1) est configurée de telle façon qu'elle puisse prélever un échantillon de tissu au point déterminé du tissu.
EP09757263A 2008-06-02 2009-06-02 Dispositif de mesure et procédé de détermination de paramètres de tissus Withdrawn EP2291118A2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102008026435 2008-06-02
DE102008064405A DE102008064405A1 (de) 2008-06-02 2008-12-22 Messvorrichtung und Verfahren zur Bestimmung von Gewebeparametern
PCT/EP2009/003920 WO2009146880A2 (fr) 2008-06-02 2009-06-02 Dispositif de mesure et procédé de détermination de paramètres de tissus

Publications (1)

Publication Number Publication Date
EP2291118A2 true EP2291118A2 (fr) 2011-03-09

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Country Link
US (1) US20110077509A1 (fr)
EP (1) EP2291118A2 (fr)
DE (1) DE102008064405A1 (fr)
WO (1) WO2009146880A2 (fr)

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WO2009146880A3 (fr) 2010-02-04
US20110077509A1 (en) 2011-03-31
WO2009146880A2 (fr) 2009-12-10

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