EP2224924A4 - Compositions et procédés destinés au traitement de la fibrose kystique - Google Patents

Compositions et procédés destinés au traitement de la fibrose kystique

Info

Publication number
EP2224924A4
EP2224924A4 EP08841991A EP08841991A EP2224924A4 EP 2224924 A4 EP2224924 A4 EP 2224924A4 EP 08841991 A EP08841991 A EP 08841991A EP 08841991 A EP08841991 A EP 08841991A EP 2224924 A4 EP2224924 A4 EP 2224924A4
Authority
EP
European Patent Office
Prior art keywords
compositions
methods
cystic fibrosis
treating cystic
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08841991A
Other languages
German (de)
English (en)
Other versions
EP2224924A1 (fr
Inventor
Richard L Watson
Anthony B Wood
Gregory J Archambeau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microdiffusion Inc
Original Assignee
Microdiffusion Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2007/082580 external-priority patent/WO2008052145A2/fr
Priority claimed from PCT/US2007/082581 external-priority patent/WO2008115290A2/fr
Priority claimed from PCT/US2007/082578 external-priority patent/WO2008052143A2/fr
Application filed by Microdiffusion Inc filed Critical Microdiffusion Inc
Priority claimed from PCT/US2008/081113 external-priority patent/WO2009055671A1/fr
Publication of EP2224924A1 publication Critical patent/EP2224924A1/fr
Publication of EP2224924A4 publication Critical patent/EP2224924A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • AHUMAN NECESSITIES
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    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • AHUMAN NECESSITIES
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    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
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    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P27/02Ophthalmic agents
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    • AHUMAN NECESSITIES
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    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
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    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
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    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
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    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
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    • A61P37/08Antiallergic agents
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    • A61P39/00General protective or antinoxious agents
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    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872Intracellular protein regulatory factors and their receptors, e.g. including ion channels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Genetics & Genomics (AREA)
EP08841991A 2007-10-25 2008-10-24 Compositions et procédés destinés au traitement de la fibrose kystique Withdrawn EP2224924A4 (fr)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US98272007P 2007-10-25 2007-10-25
US98271907P 2007-10-25 2007-10-25
PCT/US2007/082580 WO2008052145A2 (fr) 2006-10-25 2007-10-25 Procédés de traitement thérapeutique des yeux et d'autres tissus humains à l'aide d'une solution enrichie en oxygène
PCT/US2007/082581 WO2008115290A2 (fr) 2006-10-25 2007-10-25 Méthodes de soins et de traitement de plaies
PCT/US2007/082578 WO2008052143A2 (fr) 2006-10-25 2007-10-25 Dispositif de mélange et ses fluides de sortie
US4834008P 2008-04-28 2008-04-28
US4833208P 2008-04-28 2008-04-28
US4840408P 2008-04-28 2008-04-28
US4834708P 2008-04-28 2008-04-28
PCT/US2008/081113 WO2009055671A1 (fr) 2007-10-25 2008-10-24 Compositions et procédés destinés au traitement de la fibrose kystique

Publications (2)

Publication Number Publication Date
EP2224924A1 EP2224924A1 (fr) 2010-09-08
EP2224924A4 true EP2224924A4 (fr) 2011-01-12

Family

ID=42261767

Family Applications (3)

Application Number Title Priority Date Filing Date
EP08842968A Withdrawn EP2215260A4 (fr) 2007-10-25 2008-10-23 Compositions et procédés pour moduler la transduction de signal intracellulaire véhiculé par membrane cellulaire
EP08841701.9A Active EP2214707B1 (fr) 2007-10-25 2008-10-24 Compositions et procédés pour traiter une inflammation
EP08841991A Withdrawn EP2224924A4 (fr) 2007-10-25 2008-10-24 Compositions et procédés destinés au traitement de la fibrose kystique

Family Applications Before (2)

Application Number Title Priority Date Filing Date
EP08842968A Withdrawn EP2215260A4 (fr) 2007-10-25 2008-10-23 Compositions et procédés pour moduler la transduction de signal intracellulaire véhiculé par membrane cellulaire
EP08841701.9A Active EP2214707B1 (fr) 2007-10-25 2008-10-24 Compositions et procédés pour traiter une inflammation

Country Status (8)

Country Link
EP (3) EP2215260A4 (fr)
JP (6) JP5613565B2 (fr)
CN (5) CN101910412B (fr)
AU (3) AU2008316794B2 (fr)
CA (3) CA2703672A1 (fr)
IL (3) IL205317A (fr)
MX (3) MX2010004563A (fr)
WO (1) WO2009055614A1 (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6702949B2 (en) 1997-10-24 2004-03-09 Microdiffusion, Inc. Diffuser/emulsifier for aquaculture applications
WO2008052145A2 (fr) 2006-10-25 2008-05-02 Revalesio Corporation Procédés de traitement thérapeutique des yeux et d'autres tissus humains à l'aide d'une solution enrichie en oxygène
WO2008052143A2 (fr) 2006-10-25 2008-05-02 Revalesio Corporation Dispositif de mélange et ses fluides de sortie
US8445546B2 (en) 2006-10-25 2013-05-21 Revalesio Corporation Electrokinetically-altered fluids comprising charge-stabilized gas-containing nanostructures
EP2207669A4 (fr) * 2007-10-25 2011-11-02 Revalesio Corp Compositions bactériostatiques ou bactériocides et procédés
US10125359B2 (en) 2007-10-25 2018-11-13 Revalesio Corporation Compositions and methods for treating inflammation
US9745567B2 (en) 2008-04-28 2017-08-29 Revalesio Corporation Compositions and methods for treating multiple sclerosis
CA2703672A1 (fr) * 2007-10-25 2009-04-30 Revalesio Corporation Compositions et procedes pour moduler la transduction de signal intracellulaire vehicule par membrane cellulaire
US9523090B2 (en) 2007-10-25 2016-12-20 Revalesio Corporation Compositions and methods for treating inflammation
CA2722658C (fr) * 2008-04-28 2018-09-18 Richard L. Watson Compositions et procedes pour traiter la sclerose en plaques
WO2009134929A2 (fr) 2008-05-01 2009-11-05 Revalesio Corporation Compositions et méthodes de traitement de troubles digestifs
BRPI0920430A2 (pt) * 2008-10-22 2019-09-24 Revalesio Corp composições e métodos para tratar condições mediadas por metaloproteinase matriz 9 (mmp9)
US8815292B2 (en) 2009-04-27 2014-08-26 Revalesio Corporation Compositions and methods for treating insulin resistance and diabetes mellitus
BRPI1013992A2 (pt) * 2009-04-27 2016-08-16 Revalesio Corp composições e métodos para o tratamento de resistência à insulina e diabetes melito
EP2566460A4 (fr) * 2010-05-07 2015-12-23 Revalesio Corp Compositions et procédés d'amélioration des performances physiologiques et du temps de récupération
EP2799071B1 (fr) 2010-06-16 2018-10-17 Inflammatory Response Research, Inc. Lévocétirizine et montélukast pour le traitement de la grippe et le rhume
CN103347500A (zh) 2010-08-12 2013-10-09 利发利希奥公司 用于治疗tau蛋白病的组合物和方法
JP2013538803A (ja) * 2010-08-13 2013-10-17 レバレジオ コーポレイション 心血管疾患を治療するための組成物および方法
EA201391521A1 (ru) * 2011-04-13 2014-03-31 Ревалезио Корпорейшн Композиции и способы для ингибирования и/или модулирования эффекторных t-клеток, участвующих в воспалительном нейродегенеративном заболевании
JP6368459B2 (ja) * 2012-06-14 2018-08-01 松本 高明 点眼液の製造方法
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KR20150135339A (ko) 2013-03-13 2015-12-02 인플래머토리 리스폰스 리서치, 아이엔씨. 레보세티리진 및 몬테루카스트의 외상성 손상의 치료 용도
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IL205318A0 (en) 2010-12-30
JP2014169328A (ja) 2014-09-18
CN101910412B (zh) 2013-08-21
IL205318A (en) 2017-01-31
WO2009055614A1 (fr) 2009-04-30
EP2215260A1 (fr) 2010-08-11
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