EP2036528A2 - Récipient à plasma - Google Patents

Récipient à plasma Download PDF

Info

Publication number
EP2036528A2
EP2036528A2 EP20080016046 EP08016046A EP2036528A2 EP 2036528 A2 EP2036528 A2 EP 2036528A2 EP 20080016046 EP20080016046 EP 20080016046 EP 08016046 A EP08016046 A EP 08016046A EP 2036528 A2 EP2036528 A2 EP 2036528A2
Authority
EP
European Patent Office
Prior art keywords
blood plasma
container
plasma container
container according
plasma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP20080016046
Other languages
German (de)
English (en)
Other versions
EP2036528B1 (fr
EP2036528A3 (fr
Inventor
Heinz Meise
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heinz Meise GmbH
Haemonetics Corp
Original Assignee
Heinz Meise GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38806450&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP2036528(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Heinz Meise GmbH filed Critical Heinz Meise GmbH
Priority to PL08016046T priority Critical patent/PL2036528T3/pl
Publication of EP2036528A2 publication Critical patent/EP2036528A2/fr
Publication of EP2036528A3 publication Critical patent/EP2036528A3/fr
Application granted granted Critical
Publication of EP2036528B1 publication Critical patent/EP2036528B1/fr
Revoked legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1412—Containers with closing means, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1475—Inlet or outlet ports
    • A61J1/1487—Inlet or outlet ports with friction fit, e.g. connecting tubes directly to a protruding port
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1468—Containers characterised by specific material properties

Definitions

  • the invention relates to a plastic blood plasma container with a body, on one side of which a neck is provided.
  • Blood in the body of humans fulfills a variety of functions. It takes on, for example, a transport function, because the circulation of the blood numerous dissolved substances and heat are transported from the place of their production or absorption to the place of their degradation or excretion, a respiratory function, a nutrient and rinse function and a defense function.
  • the blood consists of cells, the red blood cells (erythrocytes), the white blood cells (leukocytes) as well as the platelets and surrounding fluid, the blood plasma ( Deetjen / Speckmann "Physiology” Verlag Urban & Schwarzenberg, 1992, p. 261 ). Blood plasma is thus the cell-free blood fluid.
  • the plasma is a protein-rich fluid, the composition of which largely corresponds to the interstitial fluid (Deetjen / Speckmann, loc. Cit., P. 265).
  • Containers are used for receiving blood plasma. These are usually bags or bottles.
  • plasma bags are made from DE 93 17 359 U1 known and are referred to as transfer bags. They are made of plastic film and are used for the filling, storage, transport and supply of blood and blood components.
  • transfer bags are made of plastic film and are used for the filling, storage, transport and supply of blood and blood components.
  • a disadvantage of the use of the bags their behavior has been found in the frozen state of the plasma; in this condition, due to the material properties of the film, the bags tend to break when dropped.
  • Plasma bottles are for example from the DE 200 10 825 U1 known. They are usually made of plastic and are provided with a neck. The plasma bottles are stable and avoid the aforementioned disadvantage; However, during transport and storage, the shape of the bottles adversely affects because they require more space in relation to bags.
  • the invention has for its object to provide a blood plasma container, which allows a space-saving and thus inexpensive storage and transport and at the same time provides a high security against breaking even in the frozen state.
  • this object is achieved in that the body has a substantially rectangular cross-section in horizontal section.
  • a blood plasma container is created, which can be transported and stored in a space-saving manner, whereby the transport and storage costs are reduced.
  • the container is stable to survive undamaged fall even in the frozen state of the plasma.
  • a faster freezing of the plasma due to the flatter geometry is possible with the plasma container.
  • the flat geometry also allows shock-freezing in single cartridges that previously could only be used for plasma bags.
  • the body is externally provided with a ribbing.
  • the ribbing contributes to a stabilization of the container and avoids buckling of the container. This additionally ensures that the Blood plasma container does not exceed the dimensions of the individual cassettes for shock freezing.
  • the selected as embodiment blood plasma container is made of plastic.
  • the plastic is polyethylene, preferably high density polyethylene (HDPE). But also medium density polyethylene (MDPE) or low density polyethylene (LDPE) can be used. Important in the choice of material is in addition to meeting the hygienic requirements essentially sufficient stability of the container even in the frozen state of the plasma.
  • the container consists of a body 1 which has a substantially rectangular cross section in horizontal section.
  • the body 1 has a thickness, which corresponds to about one third of the diameter of known plasma bottles.
  • the dimensions of the container according to the invention correspond approximately to those of known plasma bags; they therefore have about the same filling volume.
  • the body 1 is externally provided with a ribbing 19, which stabilizes the container and avoids bulging.
  • the body 1 has at its one end a neck 2.
  • the neck 2 is closed with a container neck surface 3.
  • the container neck surface 3 is not detachably provided on the neck 2.
  • Bottle 1, neck 2 and container neck surface 3 are formed in one piece and are manufactured in one manufacturing step.
  • In the container neck surface 3 are in the embodiment of the FIGS. 1 to 3 provided two holes are attached to the nozzle 5.
  • the nozzle 5 are not detachable and mounted close to the container neck surface 3.
  • devices 5 are provided for connecting hoses.
  • the devices 5 are in the embodiment of L-shaped elbows that are not detachably connected to the nozzle 4.
  • the hoses are not detachably arranged.
  • connection bore 61 faces the neck 2 of the plasma container.
  • the connection bores 62 and 63 are aligned at right angles to the connection bore 61. They are diametrically opposed. From the connection bores 62 and 63, connections 64 and 65 each extend, which are provided with a right angle and thus open into the connection bore 61.
  • a tubular extension piece 66 is additionally provided, which protrudes into the connection bore 61.
  • the hoses connected to the devices 5 or the connector 6 are a ventilation hose 7 and a filling hose 8.
  • the hoses 7 and 8 are made of plastics which enable sterilization.
  • the ventilation and Verismesech includes a Y-piece, which is provided with a shut-off device 91 and a branch 92.
  • the shut-off device 91 is designed as a self-sealing filter. This is made of air-permeable, hydrophobic plastic, preferably polyethylene and closes itself when liquid contact independently. As long as the self-sealing filter does not come into contact with liquid, it is permeable to air and filters the air, preventing contamination of the blood plasma with bacteria in the air.
  • a coupling connection 10 connects, in which a rubber needle valve 101 is integrated.
  • the connection 10 serves to receive a sample tube (not shown) under vacuum.
  • a recovery unit is provided at its end facing away from the container. It is provided with a switch 11 to which two tubes 12 and 13 of different lengths are connected.
  • the hose 12 has at its end facing away from the switch 11 a receptacle 14 with a protective cap 15.
  • a centrifuge bowl is connected to the receptacle 14, a centrifuge bowl is connected during the dispensing process.
  • a piercing spike 16 is arranged, on whose free end a cap 17 can be attached.
  • the insertion mandrel 16 is used for removal from bottles with physiological saline.
  • the nozzle 4 and the devices 5 according to the embodiment of the FIGS. 1 to 3 and the connector 6 according to the embodiment of the FIGS. 4 to 6 can be covered with a rotating and cap 18. It is provided with a means for locking on the neck 2 of the container.
  • the cap 18 has two slots 181 which extend from their end facing towards the container and extending axially in the direction of the end of the cap 18 facing away from the container.
  • the slots 181 are arranged diametrically opposite each other in the embodiment and are used to pass the tubes 7 and 8.
  • the cap 18 is in a position in which the tubes 7 and 8 are passed through the slots 181 unhindered.
  • the tubes 7 and 8 are cut off by means of a thermo-tongs and welded.
  • the cap 18 is actuated.
  • the cap 18 is rotated.
  • the free ends of the tubes 7 and 8 are drawn into the cap 18 ( Figures 3 and 6 ).
  • the plasma container according to the invention is highly solid due to the materials chosen. This means that it is resistant to damage even in the frozen state of the plasma.
  • the flat shape of the container allows a rapid freezing of the plasma, since the container according to the invention in relation to known plasma bottles only one third of the thickness. This ensures the preservation of globolin and coagulation factors in the plasma.
  • the space-saving design of the container cost-effective storage and cost transport is possible.

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
EP20080016046 2007-09-14 2008-09-11 Récipient à plasma Revoked EP2036528B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL08016046T PL2036528T3 (pl) 2007-09-14 2008-09-11 Pojemnik na osocze krwi

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE200720012912 DE202007012912U1 (de) 2007-09-14 2007-09-14 Blutplasma-Behälter

Publications (3)

Publication Number Publication Date
EP2036528A2 true EP2036528A2 (fr) 2009-03-18
EP2036528A3 EP2036528A3 (fr) 2009-11-04
EP2036528B1 EP2036528B1 (fr) 2012-06-20

Family

ID=38806450

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20080016046 Revoked EP2036528B1 (fr) 2007-09-14 2008-09-11 Récipient à plasma

Country Status (3)

Country Link
EP (1) EP2036528B1 (fr)
DE (1) DE202007012912U1 (fr)
PL (1) PL2036528T3 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202009001068U1 (de) * 2009-01-28 2009-04-09 Heinz Meise Gmbh Blutplasma-Behälter
PL2568949T3 (pl) * 2010-05-12 2015-11-30 Haemonetics Corp Butelka do przechowywania osocza krwi z nakrętką blokującą
DE202010012728U1 (de) 2010-09-22 2011-11-29 Deutsche Gesellschaft für Humanplasma mbH Blutplasmasammelflasche
DE202011052056U1 (de) 2011-11-22 2011-12-30 Deutsche Gesellschaft für Humanplasma mbH Blutplasmasammelflasche
DE202015102323U1 (de) 2015-05-06 2016-08-09 Octapharma Plasma Gmbh Blutplasmasammelflasche
DE202016104706U1 (de) 2016-08-26 2016-09-30 Heinz Meise Gmbh Blutplasma-Behälter

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE9317359U1 (de) 1993-10-19 1994-02-10 Heinz Meise GmbH, 58579 Schalksmühle Transferbeutel für Blut
DE20010825U1 (de) 2000-06-17 2000-10-12 Haemonetics GmbH, 81477 München Verschluss für Blutplasma-Flaschen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1216534A (en) * 1967-03-03 1970-12-23 Braun Internat G M B H B Improvements in or relating to containers for storing and dispensing medicinal liquids
BE792441A (fr) * 1972-12-08 1973-06-08 Rit Rech Ind Therapeut Flacons en matiere plastique semi-rigide.
DE20310937U1 (de) * 2003-07-17 2003-12-04 Heinz Meise Gmbh Blutplasma-Flasche
US20070181605A1 (en) * 2006-02-06 2007-08-09 Yang David U Fluid dispenser for minimizing residual fluid content
EP2067464A4 (fr) * 2006-09-25 2013-12-25 Nipro Corp Récipient pour perfusion en plastique extrudé soufflé

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE9317359U1 (de) 1993-10-19 1994-02-10 Heinz Meise GmbH, 58579 Schalksmühle Transferbeutel für Blut
DE20010825U1 (de) 2000-06-17 2000-10-12 Haemonetics GmbH, 81477 München Verschluss für Blutplasma-Flaschen

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"Physiologie", 1992, VERLAG URBAN & SCHWARZENBERG, pages: 261

Also Published As

Publication number Publication date
EP2036528B1 (fr) 2012-06-20
PL2036528T3 (pl) 2012-11-30
EP2036528A3 (fr) 2009-11-04
DE202007012912U1 (de) 2007-12-06

Similar Documents

Publication Publication Date Title
EP1108444B1 (fr) Système de connection stérile pour sytèmes médicaux ainsi que son utilisation
EP2036528B1 (fr) Récipient à plasma
DE3413692C2 (de) Blutbeutelanordnung
EP2391328B1 (fr) Récipient pour plasma sanguin
DE2824588A1 (de) Einweg-stopfen fuer vakuumroehrchen
EP2533832B1 (fr) Connecteur pour récipient contenant un agent actif médical
EP0993819A2 (fr) Poche contenant deux substances séparées devant être mélangées
DE2926434C2 (de) In einem Rohr angeordnete Filtereinrichtung für eine medizinische Infusionsvorrichtung
DE8001665U1 (de) Dialyseschlauchsystem
DE3500803A1 (de) Geraet zum vakuumverpacken von lebensmitteln und anderen gegenstaenden
DE20010825U1 (de) Verschluss für Blutplasma-Flaschen
EP3104928B1 (fr) Dispositif de raccordement stérile d'articles médicaux à usage unique
DE1966623A1 (de) Zur einmaligen benutzung bestimmte vorrichtung fuer die aufnahme und ausgabe einer dosis von verunreinigungsempfindlichen behandlungsfluessigkeiten
DE202018103931U1 (de) Vorrichtung zur Lagerung und Verabreichung von aus Blut gewonnen Augentropfen
EP1721595B1 (fr) Récipient pour délivrer des liquides médicaux
EP3290017B1 (fr) Bouteille pour plasma sanguin
DE102009015724B4 (de) Behälter zur Sicherung, Aufbewahrung und zum Transport von biologischen Proben
EP1579888A1 (fr) Raccord pour un ensemble de poches à sang
DE202016104706U1 (de) Blutplasma-Behälter
AT7917U1 (de) Blutplasma-flasche
EP0956900B1 (fr) Dispositif de prélèvement d'échantillons à partir de liquides contenus dans des tuyaux souples
WO2023280979A1 (fr) Canule d'aspiration médicale
DE202023104370U1 (de) Vorrichtung zur Abfüllung von Blutprodukten
DE2531058C3 (de) AnschluBvorrichtung zum einmaligen dauernden öffnen eines zwischen zwei Behältern angeordneten Verbindungsschlauches
DE20319628U1 (de) Blutplasma-Behälter

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA MK RS

PUAL Search report despatched

Free format text: ORIGINAL CODE: 0009013

AK Designated contracting states

Kind code of ref document: A3

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA MK RS

17P Request for examination filed

Effective date: 20100504

AKX Designation fees paid

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: HAEMONETICS CORPORATION

Owner name: HEINZ MEISE GMBH

17Q First examination report despatched

Effective date: 20110210

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

RIC1 Information provided on ipc code assigned before grant

Ipc: A61J 1/05 20060101AFI20120130BHEP

Ipc: A61J 1/14 20060101ALI20120130BHEP

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

Free format text: NOT ENGLISH

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 562601

Country of ref document: AT

Kind code of ref document: T

Effective date: 20120715

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

Free format text: LANGUAGE OF EP DOCUMENT: GERMAN

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 502008007451

Country of ref document: DE

Effective date: 20120816

PLBI Opposition filed

Free format text: ORIGINAL CODE: 0009260

REG Reference to a national code

Ref country code: SE

Ref legal event code: TRGR

26 Opposition filed

Opponent name: DEUTSCHE GESELLSCHAFT FUER HUMANPLASMA MBH

Effective date: 20120901

REG Reference to a national code

Ref country code: NO

Ref legal event code: T2

Effective date: 20120620

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120620

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120620

REG Reference to a national code

Ref country code: NL

Ref legal event code: VDEP

Effective date: 20120620

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG4D

Effective date: 20120620

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120921

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120620

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120620

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120620

REG Reference to a national code

Ref country code: PL

Ref legal event code: T3

REG Reference to a national code

Ref country code: DE

Ref legal event code: R026

Ref document number: 502008007451

Country of ref document: DE

Effective date: 20120901

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120620

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120620

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20121020

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120620

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120620

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20121022

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120620

BERE Be: lapsed

Owner name: HEINZ MEISE G.M.B.H.

Effective date: 20120930

Owner name: HAEMONETICS CORP.

Effective date: 20120930

PLAX Notice of opposition and request to file observation + time limit sent

Free format text: ORIGINAL CODE: EPIDOSNOBS2

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120620

Ref country code: MC

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20120930

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20121001

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20120920

REG Reference to a national code

Ref country code: IE

Ref legal event code: MM4A

REG Reference to a national code

Ref country code: FR

Ref legal event code: ST

Effective date: 20130531

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20120930

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20120930

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20120911

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120920

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20120930

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20120920

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FR

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20121001

PLAF Information modified related to communication of a notice of opposition and request to file observations + time limit

Free format text: ORIGINAL CODE: EPIDOSCOBS2

PLAF Information modified related to communication of a notice of opposition and request to file observations + time limit

Free format text: ORIGINAL CODE: EPIDOSCOBS2

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120620

PLBB Reply of patent proprietor to notice(s) of opposition received

Free format text: ORIGINAL CODE: EPIDOSNOBS3

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120620

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20120911

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080911

REG Reference to a national code

Ref country code: AT

Ref legal event code: MM01

Ref document number: 562601

Country of ref document: AT

Kind code of ref document: T

Effective date: 20130911

PLAB Opposition data, opponent's data or that of the opponent's representative modified

Free format text: ORIGINAL CODE: 0009299OPPO

R26 Opposition filed (corrected)

Opponent name: OCTAPHARMA PLASMA GMBH

Effective date: 20120901

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20130911

RDAF Communication despatched that patent is revoked

Free format text: ORIGINAL CODE: EPIDOSNREV1

APBM Appeal reference recorded

Free format text: ORIGINAL CODE: EPIDOSNREFNO

APBP Date of receipt of notice of appeal recorded

Free format text: ORIGINAL CODE: EPIDOSNNOA2O

APAH Appeal reference modified

Free format text: ORIGINAL CODE: EPIDOSCREFNO

APBQ Date of receipt of statement of grounds of appeal recorded

Free format text: ORIGINAL CODE: EPIDOSNNOA3O

APBY Invitation to file observations in appeal sent

Free format text: ORIGINAL CODE: EPIDOSNOBA2O

APCA Receipt of observations in appeal recorded

Free format text: ORIGINAL CODE: EPIDOSNOBA4O

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IT

Payment date: 20180921

Year of fee payment: 11

Ref country code: NO

Payment date: 20180920

Year of fee payment: 11

Ref country code: DE

Payment date: 20180918

Year of fee payment: 11

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: SE

Payment date: 20180924

Year of fee payment: 11

Ref country code: CZ

Payment date: 20180903

Year of fee payment: 11

Ref country code: PL

Payment date: 20180829

Year of fee payment: 11

REG Reference to a national code

Ref country code: DE

Ref legal event code: R064

Ref document number: 502008007451

Country of ref document: DE

Ref country code: DE

Ref legal event code: R103

Ref document number: 502008007451

Country of ref document: DE

APBU Appeal procedure closed

Free format text: ORIGINAL CODE: EPIDOSNNOA9O

RDAG Patent revoked

Free format text: ORIGINAL CODE: 0009271

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: PATENT REVOKED

REG Reference to a national code

Ref country code: NO

Ref legal event code: MMEP

REG Reference to a national code

Ref country code: FI

Ref legal event code: MGE

27W Patent revoked

Effective date: 20200323

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CZ

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20190911

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NO

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20190930

REG Reference to a national code

Ref country code: AT

Ref legal event code: MA03

Ref document number: 562601

Country of ref document: AT

Kind code of ref document: T

Effective date: 20200323

REG Reference to a national code

Ref country code: SE

Ref legal event code: ECNC

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PL

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20190911