EP1986720A1

EP1986720A1 - Overlapping display

Info

Publication number: EP1986720A1
Application number: EP07701863A
Authority: EP
Inventors: Markus Bollenbach; Edgar Hommann; Benjamin Scherer; Céline JOST; Ursina Streit; Daniel Künzli
Original assignee: Tecpharma Licensing AG
Current assignee: Tecpharma Licensing AG
Priority date: 2006-02-14
Filing date: 2007-02-07
Publication date: 2008-11-05
Also published as: US20090149809A1; AU2007214905A1; DE102006006796A1; JP2009526576A; WO2007093067A1; CN101420996A

Abstract

Device for administering an injectable product, comprising: a housing with a housing wall (1), a viewing element (2) which is formed on the housing and with which a view area can be observed, an emptying display (4) which is movable inside the housing and relative to the housing, at least partially through the view area, and a view release member (3) which is movable relative to the housing, characterized in that the view of the emptying display can be faded over and/or freed with the view release member.

Description

Overlapping display

The invention relates to a device for administering an injectable product, such as a liquid medicament, such as insulin, heparin, a ^"growth hormone or an osteoporosis preparation. In the apparatus, it may in particular be an injection device such as a pen injector or auto-injector.

Devices of the type mentioned are known in many designs. In such devices, particularly in auto-injectors, it may be advantageous to the user of the device to know in what state, for example piercing or dispensing, the device is located.

For this purpose, US Pat. No. 6,692,469 proposes an injection device which comprises a sleeve for receiving a syringe and a trigger mechanism connected to the sleeve. The housing of the triggering mechanism has a window through which marks can be seen indicating whether the injection device has been triggered or not.

International Patent Application Publication 2004/047891 discloses a device for automatically injecting a drug. The autoinjector described in the Laid-Open Application consists of two main components, namely a reservoir part which accommodates a filled syringe and a power pack in which the parts used for automatic puncturing and dispensing of the syringe are accommodated. The power pack has a display window made of a transparent material, which allows to observe a slidably recorded display from the outside. In one embodiment of the device, the display is visible under the transparent sleeve in any operating condition of the device. The ad will not move until the Product dispensing if a needle located on the syringe has been punctured. Prior to the piercing and dispensing operation a release button can be retracted, whereby a sleeve provided with a warning color, also by the ^'see-through sleeve is seen, whereby the user of the device detects that the device is ready for triggering.

In another embodiment of the device of the international patent application, the dispensing indicator is already moved during the piercing operation of the needle, the display being covered by a cover from the beginning up to and including the end of the piercing process. The dispensing indicator can not be seen until the dispensing process begins. In this case, the discharge display appears under the non-movable cover.

From both embodiments of the international patent application it is not apparent to the user of the device by means of the display whether the device is still in the piercing state or not.

The object of the invention is to provide a device and a method for administering an injectable product, which allow a user of the device to be able to recognize different states of the device in a simple manner.

The object is solved by the features of the independent claims. Advantageous developments emerge from the dependent claims.

The device according to the invention for administering an injectable product may be an injection device, preferably an autoinjector or injection pen. The administration of the injectable product may comprise a plurality of sequences in a device according to the invention, in particular in an autoinjector. For example, a piercing sequence in which a needle is pierced into a body tissue and a dispensing sequence in which the liquid medicament, for example, is dispensed, may be provided. Advantageously, the Ausschüttsequenz or preferably the Einstechsequenz in the following a Ausschüttsequenz can be activated. The device may comprise a housing which comprises, for example, two or more housing parts which are detachably or non-detachably connectable or connected to one another. For this purpose, inter alia, a screw, bayonet or snap lock in question. A mechanical sequence control, which controls the puncture and / or Ausschüttsequenz, for example, be included in a proximal housing part and a product container in a distal housing part or be. By "proximal" is meant the side opposite the needle and "distal" is understood to mean the side of the in particular elongate injection device lying on the needle. The product container, in particular an ampoule, can be exchangeably inserted into the distal housing part or can be formed directly from the distal housing part. The housing can also be formed in one piece.

The housing has a housing wall. On the housing, in particular and the housing wall a see-through element is formed. The see-through element serves a user of the device in order to be able to look from the outside through the housing wall into the interior of the housing. This area is referred to as the visual area below. In particular, the viewing area may be a projection of the see-through element in the radial direction to the longitudinal axis of the device. By "within the field of view" is meant also elements which are within the projection of the see-through element but, for example, because it obscures another part through which the see-through element is not visible. The see-through element may be a window or opening in the housing wall. In particular, the see-through element may also be a part of a transparent material formed by the housing wall or inserted into the housing wall. Preferably, the transparent material may be glass or a clear or colorless plastic. In preferred embodiments, the see-through element may have an enlarging or reducing optical effect. For this purpose, the see-through element may be a lens or the like.

The device has a particular mechanical discharge display, which is at least partially movable within the housing relative to the housing through the viewing area and thereby at least partially and depending on the switching state of the device can be seen by the user. Preferably, the dispensing indicator is in Longitudinal direction of the device movable. The dispensing indicator serves to inform the user whether the product or how much of the product has been dispensed. The product is preferably located in a product container which is contained in the device or can be inserted into the device. The product may be able to be released from the product container by a piston acting on the product. Preferably, during product dispensing, the piston moves relative to the product container. Piston and dispensing indicator may be coupled together so that when moving from one of dispensing indicator and piston, the other at least partially join the movement of the one. For example, one may travel a certain distance while moving, with the other traveling a distance greater than, less than, or equal to that of the other. For example, one may move at a certain speed that is greater or less than or equal to the speed of the other. Preferably, one performs the movement in the same direction as the other. Particularly preferably, during the dispensing movement, the piston is moved by a greater distance than the dispensing indicator. In particular, the piston may cover a portion of its travel to be traversed for a full payout so that the movement of the piston in that portion is completely decoupled from the payout indicator. For example, as the piston moves in the section, no force acting on the dispensing indicator is changed. Preferably, no force acts on the discharge indicator while the piston is moving in the portion. It is generally preferred that the dispensing indicator be stationary relative to the housing when the piston is moved in the section.

In particular, when the piston has traveled the distance in which its movement is decoupled from the dispensing indicator, the piston can travel a residual path for product dispensing in which the movement of the piston is coupled to the dispensing indicator. The coupling may, for example, be of the type that the dispensing indicator participates in the movement of the piston. Preferably, the dispensing indicator returns the same path as the piston in the residual path. In particular, it is preferred that the dispensing indicator is moved at the same speed as the piston as it traverses the residual path. Depending on the position of the piston, the dispensing indicator can be located within the field of vision with a certain range and / or can be seen in particular. There may be several areas provided on the discharge display. In several areas, these can be arranged one behind the other in the direction of movement, so that different areas pass through the viewing area during the movement through the viewing area. Preferably, each area has a different information than the other areas or an adjacent area. Thereby, the user of the device can recognize from the information appearing at a certain moment under the transparent display whether or how much product has been released from the product container.

For example, a first area may be located in the viewing area, which is moved out of the field of view during the product dispensing, so that another, such as a second area, is located in the viewing area when the product has been completely dispensed. Between the first area and the second area, an intermediate area can be arranged, which is located in the viewing area during the product distribution or can be moved through the viewing area and can be seen. As a result, the user of the device can recognize that the product distribution has already begun, but not yet completely completed, since this would only be the case, for example, if the second area were located within the field of vision.

The information of the areas may in particular be a material property, a character, an image and / or a color information, wherein at least the information of the first area differs from that of the second area. The information of the first area may be similar, such as different letters. The information may also be diverse, such that, for example, the first area has a letter and the second area has color information. The material property may be, for example, the type of material used or a surface texture. A character may be, for example, a letter, a symbol or the like. For example, a color information can be a color that is meaningful for the respective ejection state. By way of example only, the first area may have a less noticeable color, such as "green" and the second area have a striking color or signal color such as "red". The user of the device will initially perceive the less noticeable color through the see-through element. As product dispensing progresses, the user of the device can see through the see-through element the area of signal color that moves into the field of view. For example, to give the user of the device information that the device is still in the product distribution sequence, an intermediate region may be arranged between the first region and the second region, containing both information of the first region and information of the second region can have. Alternatively, the intermediate area may also have its own information that is different or different or similar from the information of the first and / or the second area. For example, the intermediate area may have predominantly color information of the adjacent area at approximately the point where it adjoins the adjacent area. Preferably, since the information of the first and second areas are different, in the intermediate area, the color information of the first area may change from the first area in the course to the second area into the color information of the second area. The change of the color information may for example be homogeneous, so that in the intermediate area there are a multiplicity of colors perceptible to the human eye, or the colors are mixed. The change in the color information can also be inhomogeneous, with fields preferably having, for example, two fields with different colors whose respective width or area proportions increase or decrease. For example, the intermediate area may include the colors of the first and second areas. For example, the proportion of the color of the first region in the course from the first to the second region may decrease and the proportion of the color of the second region may increase. Preferably, the color of the second region in the course from the first region to the second region increases as the color of the first region decreases in the course from the first region to the second region.

The device further comprises a visual release member with which the view of the dispensing indicator can be blended. "Blend the view" means that the view of the dispensing indicator can be blocked, so that the dispensing indicator is not visible, or that the view of the dispense indicator, for example, over a transparent material is possible, but the part located in the viewing direction behind the view release member with a certain information of the visual release member is blended. The information may be, for example, a particular color of the transparent material or characters or a letter or image information that is applied to the transparent or opaque visual release element.

The invention is characterized in that the Sichtfreigabeglied is movable relative to the housing, whereby the view of the discharge display can be released. "Release the view of the dispensing indicator" means that the dispensing indicator can be seen, or that, in the case of a transparent material overlay, the information that the user of the device can extract when interleaving changes when released. The visual release member is preferably movable in the longitudinal direction. More preferably, the view of the dispensing indicator is released when the visual release member is moved in the distal direction. The visual release member may, at least in part, move through the viewing area, similar to the dispensing indicator. The visual release member may be arranged outside the housing, for example, in order to be able to be pushed over the see-through element, for example. The visual release member may preferably be located in the viewing direction below the see-through element or within the housing. Particularly preferably, the visual release element is arranged between the housing wall and the discharge display, whereby advantageously the view of the discharge display can be blended or released.

The product container contained in the device or insertable into the device can be connected to a needle, which can be inserted into the skin of the patient. The needle may be slidable relative to the housing along its longitudinal axis. The needle is preferably surrounded by the housing or a needle protection sleeve arranged on the housing in such a way that the needle can protrude distally from the housing or the needle protection sleeve for insertion, for example by a certain puncturing length. The needle may be coupled to the visual release member such that upon movement of one of the visual release member and the needle, the other at least partially participates in the movement of the one. Preferably, the visual release member in the same direction and / or move in about the same way and / or at the same speed as the needle during insertion. The needle can be mounted relative to the container movable or axially fixed to the container, in particular directly to the container, so that the needle and container can perform a common piercing movement. The embodiments for the coupling of the needle with the visual release member preferably apply according to the coupling of the Sichtfreigabeglieds with the container.

The needle and / or the product container may be displaceable relative to the housing along the longitudinal axis between a starting position and a piercing position. In the starting position, the device is in the "idle state", ie before triggering the dispensing and Einstechsequenz. In particular, the needle is within the housing or the needle guard. In the puncture position, the needle has emerged distally from the housing or the needle guard with a desired Eintechlänge. The needle / product container reaches the puncturing position by triggering the puncture sequence in the starting position.

The visual release member preferably has a first area located in the field of view when the product container is in its or the needle is in its home position. For example, the first area may include information that is recognizable by the see-through element. Based on this information, the user of the device can optically determine that the needle is not yet pierced or the device is in its initial position. The information of the first area may be, for example, a material property of the material of the first area, a character, an image and / or a color information. In particular, the information may be similar to the information of the first or the second area of the dispensing indicator. In preferred embodiments, the first region is transparent or opaque. If the first area is opaque, the view behind the visual release element is not possible in the direction of sight. In the case of a transparent first region of the visual release element, it is possible to see in the direction behind the visual release element. In particular, the first region may be clear or colorless, or a transparency provided with a particular color exhibit. In addition, further information may be arranged on the surface of the first region, which is particularly preferred in the case of a transparent first region.

Preferably, adjacent to the first region is a second region located in the field of view when the needle or product container is in the puncture position. This has the advantage that the user of the device can optically recognize when the needle has emerged with the desired insertion length of the housing or the needle guard, or is inserted into the body tissue. More preferably, the user can read the dispensing indicator, for example, through the see-through element and the second area of the visual release member. By way of example, the second area of the visual release member may be smaller, larger or approximately the same size as the see-through element. In particular, the second region of the visual release member may have approximately the shape of the see-through element.

In particular, the second area may connect to the visual release member or be a window in the visual release member. The second area may or may not be a component of the visual disclosure element. For example, the vision release member may be terminated proximally of the first region such that as the needle or container moves from the home position to the puncture position, for example, the visual release member or first region is substantially completely moved out of the field of view. The region which adjoins the visual release member proximally may therefore be referred to as the second region, since in particular and generally in the second region the view of the distribution is functionally released.

In another embodiment, the second region may be an element of the visual release member. The second area can then be a window or made of a transparent material. Preferably, in a transparent second region, the material is clear or colorless transparent. However, it is generally preferred that, in the case of a transparent first region, the transparent material of the second region has a different color than the transparent material of the first region. Thus, the user of the device can easily and safely recognize when the needle is in its piercing position. In a further embodiment, an intermediate region may be arranged between the first region and the second region in the longitudinal direction of the device, which is moved at least partially through the viewing region during the movement of the product container or the needle from the starting position into the puncturing position or is within the field of vision. The intermediate region may comprise a character, an image, a color information and / or a material property, by which it can be seen that the product container and / or the needle are moving. For the intermediate region of the visual release member, the features of the intermediate region of the dispensing indicator preferably apply correspondingly.

In one embodiment, in the starting position, the dispensing indicator, in particular with its first region, can be located in the viewing region, with the dispensing indicator or its first region being superimposed by the visual release member, in particular its first region. In this embodiment, it is preferred that the vision release member move in the plunge sequence relative to the housing and to the dispensing indicator. In other words, in the starting position, the first region of the visual release member and the first region of the dispensing indicator are in the field of view.

In another preferred embodiment is in the starting position, the discharge display, in particular its first area. out of sight. In particular, the first region of the dispensing indicator can be in the region of the second region of the visual release member, for example at the same axial height. The first area of the visual release member can be located in the starting position in the field of vision and can be seen. Upon initiation of the puncture sequence, the visual release member and the dispensing indicator are moved together in the distal direction relative to the housing. In particular, the visual release member and the discharge display perform the piercing movement of the needle together, namely, for example, without relative movement to each other. In the piercing position, and in particular before the product dispensing, preferably the first region of the dispensing indicator and the second region of the visual disengaging member are within the field of view, which is generally preferred, so that the Users of the device can see the first area of the discharge display and read their information. Thus, the user of the device can visually determine that the needle is in its puncture position and no product has yet been dispensed.

Preferably, after reaching the puncturing position, the dispensing sequence is started, for example automatically or manually. Preferably, during the product dispensing sequence, the visual release member does not move relative to the housing or is fixed relative to the housing. During product dispensing, the dispensing indicator may move relative to the housing and the visual release member. In this case, the first region of the discharge display is moved out of the field of view, so that the user can read off the information of the intermediate region of the discharge display and then the information of the second region of the discharge display by the see-through element, if necessary.

In some embodiments, the intermediate area and / or the second area of the dispensing display may be omitted, so that the user may look behind the dispensing display in the viewing direction during or after product dispensing. However, it is preferred that the second portion of the dispensing indicator is in the field of vision after product dispensing has been completed and can be read at a glance through the viewing element and the second region of the visual release member.

Preferably, a resilience means, such as a propulsion spring, may for example be provided in the form of a helical spring which can move the visual release means and / or the product container and / or the needle and / or the dispensing indicator in the piercing direction. The elasticity agent may be in a pretensioned state in the initial state of the device and locked against relaxation. For example, the prestressed elasticity means can be supported on a housing-fixed element, in particular a mechanism holder and on an element coupled to the visual release element or directly on the visual release element. A coupled to the Sichtfreigabeglied element may for example be a feed element, the the visual release member entrains in relaxing the elasticity agent in the distal direction. The advancing element is preferably movable along the longitudinal axis of the device relative to the housing. For example, the feed element can be secured against movement axially fixedly connected to the housing or the mechanism holder and preferably radially movable locking member against movement. For this purpose, for example, the locking member engage in the feed element.

The device may for example comprise an output member which is movable along the longitudinal axis of the device and relative to the housing. The output member may act directly or indirectly on the piston of the product container. For example, the output member may indirectly act on the piston via a piston rod. In particular, the piston rod can already form the piston. It is also conceivable that the output member takes over the function of the piston rod and acts directly on the piston. For example, the output member can form piston rod and piston. Preferably, the output member is locked in the home position and during the Einstechsequenz against movement in the longitudinal direction relative to the feed element. For example, the feed element may have a blocking element which can engage in the output member. Preferably, the blocking element is axially fixed and radially movable to the feed element. For example, the output member may have a radially outwardly projecting collar, which engage behind the locking element and thus can prevent movement of the output member in the distal direction. Preferably, the output member is sleeve-shaped. In particular, an elasticity means, in particular a discharge spring may be provided, for example in the form of a helical spring, which can propel the driven member during the product discharge sequence in the discharge direction. In particular, the elasticity means can be accommodated within the driven member.

Preferably, the device has a triggering element, which allows the locking member to disengage from the feed element, so that the propulsion spring can relax. In a preferred embodiment, the propulsion spring in this case takes with the feed element, which in turn entrains the dispensing indicator and the visual release member. The advancing element preferably also takes that Product container or needle with. Feed element and view release member may be in particular in one piece. Preferably, the dispensing indicator and the visual release member are entrained by the same path and / or at the same speed, for example, without relative movement from each other by the feed element. In particular, during the puncturing sequence, the output member can also be taken along by the feed element without relative movement to the feed element.

After completion of the piercing sequence, it is preferred that the output member is movable relative to the feed element. It is also preferred that the advancing element is locked at a movement relative to the housing. Particularly preferably, the blocking element, which blocks the output member in the starting position and during the piercing sequence provided to release the locking engagement with the driven member at the end of Einstechsequenz or at the beginning of Produktausschüttungssequenz and at the same time in a locking engagement with a housing-fixed element, for example the mechanism holder , to get. Preferably, the path traveled by the advancing element during the plunge sequence substantially corresponds to the travel that the needle and / or container travel during the plunge sequence.

After release of the output member at the beginning of the product discharge sequence or at the end of the plunge sequence, the output member may, for example, move around a portion without taking along the discharge indication, in particular moving the piston about its portion. Preferably, the output member takes after the portion of free movement, the discharge display in its movement in the delivery direction. At the same time, the output member can move the piston of the container by the same amount, for example, by the remaining distance, as the discharge display. Particularly preferably, the second region of the dispensing indicator is in the field of vision precisely and can be seen when the piston has been completely displaced to its most distal position in the container. The advantage here is that the user of the device can visually recognize through the see-through element that the piston has now reached its most distal position and the product has been completely released. The product container may be in preferred embodiments, element of a device to be inserted or inserted module. The module preferably comprises an axially fixed to the distal housing part connectable guide member and a relative to the guide member longitudinally movable ampoule holder, in which the product container is or can be accommodated. The ampoule holder can be pressed, for example by a spring in a proximal position, namely the starting position. In the puncturing sequence, the ampoule holder and the product container are pressed together against the spring force in the distal position, namely the setting position. The guide member preferably comprises at least one latching means, so that ampoule holder and guide member can lock axially fixed at the puncturing position. The module is preferably marketed with the product, the product occluding piston, and a piston rod attached to the piston. Further, a suitable needle may be fitted with a needle sheath such that only the needle sheath needs to be removed from the module for use.

The method on which the invention is based serves to display various states of the device for administering the injectable product. The method displays various information that can be read by the see-through element. This information includes at least information that the product container located in the device is in a starting position, information that the product container is in the piercing position, and information that the product contained in the container has been dispensed. Advantageous process characteristics result from the operation of the injection device according to the invention.

Embodiments will be described below with reference to figures. The thereby becoming apparent features each individually and in combination, the invention advantageously further. Show it:

FIG. 1A is a sectional view of an injection device in the initial state,

FIG. 1B shows a sectional view of the longitudinal axis rotated by 90 °

Inj ektionsvorrichtung of Figure IA, Figure 2A is a sectional view of the injection device of Figure IA in a patch on a body tissue state, Figure 2B is a rotated about the longitudinal axis by 90 ° sectional view of

Injection device of Figure 2 A, Figure 3A is a sectional view of the injection device of Figure IA in a tripped state in the starting position at the beginning of

Einstechsequenz, Figure 3B a rotated about the longitudinal axis by 90 ° sectional view of

Injection device of Figure 3A, Figure 4A is a sectional view of the injection device of Figure IA in the

Puncture position at the end of the plunge sequence and at the beginning of the

Produktausschüttsequenz, Figure 4B a rotated about the longitudinal axis by 90 ° sectional view of

FIG. 5A is a sectional view of the injection device from FIG. 1A in a dispensed state at the end of the product dispensing sequence, FIG. 5B is a sectional view rotated through 90 ° about the longitudinal axis

Injection device of Figure 5 A, Figure 6A is a sectional view of the injection device of Figure IA in a locked state, Figure 6B is a rotated about the longitudinal axis by 90 ° sectional view of

Injection device from FIG. 6 A,

Figure 7 is a schematic representation of a single visual release element and

Figure 8 is a schematic representation of a single discharge display.

Figures IA to 6B show the same injection device in the form of an auto-injector in different switching states and views. In the following, the parts of the device will be described with reference to FIGS. 1A and 1B, whereby this description also applies correspondingly to FIGS. 2A to 6B. The injection device comprises a mechanism, with a mechanical sequence control, with which a product container 5 contained in the injection device is first displaced in a distal direction during a puncturing sequence, so that the product container 5 on the product container 5 attached needle 6 is inserted into a body tissue of a patient, wherein after the plunge sequence during a Ausschüttsequenz the piston 7a is moved in the product container 5 in the distal direction, so that the product contained in the container 5 through the needle 6 in the body or the Body tissue of a patient is released.

The injection device comprises a distal housing part 18a and a proximal housing part 18b, which are connected to a detachable connection, in particular a bayonet closure 18c. In the proximal housing part 18b, a mechanism holder 10 is received, which is rotationally and axially fixedly connected to the proximal housing part 18b. For the axial fixing of the mechanism holder 10, this is surrounded with its end sides axially between a radially inwardly protruding projection of the proximal housing part 18b and a proximal to the proximal housing part 18b plugged cap 19. The mechanism holder 10 surrounds a feed element 9, which is displaceable relative to the mechanism holder 10 along the longitudinal axis of the injection device. The sleeve-shaped feed element 9 can slide with its outer peripheral surface on the inner peripheral surface of the approximately sleeve-shaped mechanical holder 10 along. Between a distal end face of the mechanism holder 10 and a proximal end face of a arranged at the distal end of the advancing element 9 Ringfiansschs a spring 14, in particular a coil spring is arranged, which in a pressure-biased state, the feed element 9 relative to the mechanism holder 10 in the distal direction a feed force applied.

The distal end surface of the annular flange attached distally to the advancing element 9 can act in a direction along the longitudinal axis on a visual release member 3, which is displaceable along the longitudinal axis in the proximal housing part 18b. The visual release member 3 is coupled to the product container 5 such that upon movement of the visual release member 3 in the distal direction, the product container 5 is also moved in the distal direction, namely in the piercing direction of the needle 6. Movement of the visual release member 3 in the distal direction does not yet cause movement of the piston 7a within and relative to the product container 5. By means of a pressure-biased spring 20, the product container 5 and the Sichtfreigabeglied 3 are pressed in the proximal direction of the injection device. The power the spring 20 with which the visual release member 3 is pressed in the proximal direction is smaller than the force of the spring 14, with which the advancing member 9 and the Sichtfreigabeglied 3 can be moved in the distal direction, when the advancing element 9 is released for movement along the longitudinal axis so that the product container 5 can be moved with the needle 6 in the distal direction for piercing the needle 6 into the body tissue.

Within the feed element 9, a sleeve-shaped output member 8 is arranged, which can be moved for a Ausschüttsequenz relative to the feed element 9 along the longitudinal axis when it is released for axial movement. At the proximal end of the output member 8 is a collar 8b which projects radially outward. Between output member 8 and the feed element 9 is an annular groove whose groove width is greater than the amount that the collar 8b projects radially from the output member 8. To form the annular groove, for the storage of the output member 8 and for the movement of the dispensing indicator 4, the dispensing indicator 4 engages with a sleeve-shaped portion from the distal side into the inner diameter of the advancing element 9 and surrounds the driven member 8.

The distal end of the output member 8 has an end face 8a which acts as a stop face and against which a spring 15, in particular a helical spring, can be supported. The pressure biased spring 15 is supported at its other end on a distal surface of a Änschlagselements, which is formed at a proximal portion of the advancing element 9. The spring 15, which may in particular have a greater spring constant than the spring 14, the driven member 8, when it is released, drive in the distal direction along the longitudinal axis. The distal end face of the output member 8 comes into contact with a piston rod 7 or with a dome-shaped element arranged at the proximal end of the piston rod 7, whereby the piston 7a located distally on the piston rod 7 is moved in the product container, whereby the product passes through the needle 6 is discharged when the output member 8 is moved in the distal direction.

At the proximal end of the advancing element 9, a locking element 12 which is movable relative to the advancing element 9 along the longitudinal axis is arranged. The Locking element 12 is forked and engages around the longitudinal axis with two locking portions 12A. The locking portions are each guided in a groove-shaped guide, which is formed by the feed element 9. The locking element 12 is acted upon by a spring 13 with a force in the distal direction. The spring 13 is supported on the proximal end of the locking element

12 and at a proximally arranged therefrom feed element fixed element, namely on a holding web. The spring 13 may be, for example, a helical or combined helical and spiral spring or a leaf spring. For example, the retaining web may be formed of a spring material and have a shape that can act on the locking element 12 directly with a spring force, so that the spring

13 can be omitted because the locking element 12 takes over the task of the spring 13.

A movement of the locking element in the distal direction is prevented in particular by blocking the locking element 12 with its locking sections 12A from the collar 8b of the driven member 8. The collar 8b is in turn prevented by the cam-shaped locking elements 9b, which are each arranged on an arm 9b and resiliently connected to the advancing element 9, in particular in one piece, to a movement in the distal direction.

The housing wall 1 of the proximal housing part 18b has a see-through element 2, which is designed as a window. Through the see-through element 2, the viewer can look from outside the device in the direction of the device. In FIGS. 1A to 3 B, the view into the interior of the device is blocked by the visual release member 3. The visual release member 3 has a first region 3 a, which is in the starting position of the device, namely before the puncture and Ausschüttsequenz, in the longitudinal direction of the device at the same level with the see-through element 2. As also shown in FIG. 7, the first area 3 a has a first information, which is shown in the form of a hatched area. Similarly, the information could be in a particular color, such as red, or with the aid of a character or letter (not shown). On the basis of this information of the first area 3a, the user of the device can recognize that no product distribution or piercing process has yet taken place. If, as shown in FIGS. 4A and 4B, moves the released feed element 9 in the distal direction, the locking element 9b passes after a certain distance, which preferably corresponds approximately to the path by which the product container 5 is moved to piercing, approximately at an same axial height as a locking groove 10a. The locking groove 10a is formed by the mechanism holder 10. The latching groove 10a may be a recess or an annular circumferential recess for the blocking elements 9b. Once, as shown in Figure 4 A, the locking groove 10a and the locking element 9b are at an axially equal height, due to the spring force of the arms 9a and / or the spring force of the spring 13 and / or due to the spring force of the spring 15 in connection moved with the sliding of the collar 8b radially outward into the locking groove 10a. This starts the ejection sequence.

During the plunge sequence, driven by the spring 14, on the one hand, the output member 8 with its biased drive spring 15 and on the other hand the visual release member 3 and the discharge display 4 taken. The visual release member 3 in turn takes the product container 5 together with the needle 6 fastened to its distal end for a piercing movement. In this case, the first area 3 a of the visual release member 3 is moved out of the field of view of the see-through element 2, whereby, initially, an intermediate region 3 c of the visual release member 3, as shown for example in Figure 7, enters the field of view of the see-through element 2, which the user the device can see that the needle 6 is during the Einstechsequenz. Upon reaching the puncturing position, the second area 3b of the visual release member 3, which was initially covered by the housing wall 1, moves into the viewing area of the see-through element 2. The second area is in the form of a window. Since the dispensing indicator 4 is moved distally along with the visual release member 3 during the puncture sequence, the user of the device can look at the dispensing indicator 4 through the see-through member 2 and the second portion 3b of the visual release member 3. Before distribution of the product, the dispensing indicator 4 is located at an axial height with the second region 3b of the visual release member 3. The user can therefore read the information of the first region 4a of the dispensing indicator 4 at the end of the puncturing sequence or at the beginning of the dispensing sequence. As shown in FIG. 8, the first area 4a may contain information consisting of a hatched area as shown herein or in particular in a special coloration such as "yellow" may exist. By changing the color appearing in the see-through element 2, the user recognizes the changed operating state of the device.

With reference to the dispensing display 4, unlike the configuration shown in FIGS. 1A to 6B, the dispensing display 4 can be extended in the distal and / or proximal direction. In the case of a proximal extension of the dispensing indicator 4, the second region 4b is preferably located on or on the proximal extension. In the case of a distal extension of the dispensing display 4, the first area 4a is preferably located on or on the distal extension.

After started Ausschüttsequenz the collar 8b is no longer blocked by the locking element 9b, whereby the spring 15 drives the driven member 8 in the distal direction and thus the piston 7a via the piston rod 7 for a product distribution. At the same time, the locking element 12 is released for an axial movement, so that the spring 13 of the locking element 12 moves so far that the locking portions 12a push in front of the locking element 9b. A movement of the locking elements 9b of the locking groove 10a is prevented, since the locking portions 12a, the movement that would cause the locking element 9b in a movement out of the locking groove 10a blocked. Thus, the feed element 9 is axially fixedly connected to the housing. During the movement of the output member 8 about the path z, the output member 8 initially only carries the piston rod 7, which also moves the piston 7a approximately around the path z. The dispensing indicator 4 is traversed while the path z is not yet moved. After passing through the path z of the radially projecting collar 8b of the output member 8 in an axial stop with a stop 4b, which is located proximally of the sleeve-shaped portion of the discharge display 4. Due to the driving force of the spring 15 and the collar 8b, the discharge indicator 4 is taken along the remaining path, which corresponds to the total stroke of the piston minus approximately the distance z, until the piston 7a has completely displaced the product from the product container 5. During the product discharge sequence, the discharge display 4, in particular its first area 4a, is moved out of the field of view. Since the discharge display 4 has no second area 4b, but the second area 4b adjoins the discharge display 4 proximally, as in FIGS 6A, as information for successful product distribution, the look under the dispensing indicator 4 is released.

Alternatively, in an injection device configured with a dispensing indicator 4 according to FIG. 8, during the product dispensing sequence, the first region 4a of the dispensing indicator 4 is moved out of the field of view of the see-through element 2 in the distal direction. In this case, an intermediate region 4c is first moved into the field of view, whereupon the user of the device recognizes that the product discharge sequence has started but is not yet completed. Upon reaching the end position of the piston, the area 4b is moved into the field of view of the see-through element 2, whereupon the user recognizes that the product discharge has ended.

Referring to FIG. 8, the information that the area 4b has is symbolically represented by a hatched area. For example, the area 4b may have a "green" color. In the intermediate area 4c are both the information of the first area 4a, as well as the information of the second area 4b. As the approach in the intermediate region progresses from the first region 4a to the second region 4b, the information of the first region 4a decreases and that of the second region 4b decreases. Thus, the user of the apparatus can estimate how far the product discharge has progressed by how far the intermediate portion 4c has already moved in the longitudinal direction.

It is preferred that the dispensing movement of the output member 8 can not take place until the needle 6 has completed its piercing movement. It is further preferred that the puncturing sequence can only be started,. when designed as a needle cover transfer member 16 is pressed firmly enough at the puncture site on the body tissue. When the device is pressed onto the body tissue, the transmission member 16 is displaced relative to the distal housing part 18a. From the proximal housing part 18b, a switching element 17 is movably mounted along the longitudinal axis. The switching element 17 is entrained in the movement of the transfer member 16 in the proximal direction. The transmission member 16 is against the force of a spring 20 and / or a spring 21 in the proximal direction pressed. The switching element 17 can be moved in the proximal direction against the force of the spring 21.

If, as shown in Figures 2A and 2B, the switching element 17 has been moved in the proximal direction, via the movement of a trigger element 11 in the radial direction, the switching element 17 via a arranged on the switching element 17 gear surface (not shown) even further in proximal Direction to be moved, so that, as shown in Figures 3 A and 3B, the locking member 10 b is no longer blocked by a holding stage 17 a of the switching element 17. In this switching state, the locking member 10b is at the axial height with a release stage 17b, which allows the locking member 10b to get out of locking engagement with the advancing element 9, whereby the Einstechsequenz is started. The advancing element 9 may, for example, have one or more annular recesses, for example, in which the locking member 10b may engage with the advancing element 9 for the locking engagement.

As shown in FIGS. 6A and 6B, after the piercing and dispensing sequence have taken place, as the injection device is removed, the needle cover 16 is pushed over the needle 6 by a return spring 21 so far in the distal direction that the needle 6 completely disappears into the device , This reduces a risk of injury to the user of the device. At the same time, the switching element 17, after the trigger element 11 has moved back into its initial position and the switching element 17 has released, moved back by the spring 21 in its initial position shown for example in Figures IA and IB. In contrast to the starting position (for example, FIG. 1A), the user recognizes from the changed information under the see-through element 2 that the device has already been used. Bezusszeichenliste

housing wall

Through element

Visual release element a first area b second area c intermediate area

Average display a first area b second area c intermediate area d stop

product container

needle

piston rod

Output member a End face b collar

Feed element a Arm b Locking element c Locking groove 0 Mechanism holder 0a Locking groove 0b Locking element 1 Release element 2 Locking element 2a Locking section 3 Elasticity means / spring 4 Elasticity / driving spring 5 Elasticity / discharge spring 6 Needle protection sleeve 7 Switching element 7a Holding step 7b Release step 8a distal housing part 8b proximal housing part c Bayonet lock

cap

Return spring

feather

Claims

claims

1. A device for administering an injectable product, comprising: a) a housing with a housing wall (1), b) a see-through element (2) which is formed on the housing and with which a viewing area can be seen, c) a dispensing indicator ( 4) movable within the housing and at least partially through the viewing area relative to the housing, d) a visual release member (3) movable relative to the housing, characterized in that with the visual release member (3) the view of the Pour display (3) can be blended and / or released.

2. Device according to the preceding claim, wherein the see-through element

(2) is a window or a transparent material.

3. Device according to one of the preceding claims, wherein the

Sichtfreigabeglied (3) between the housing wall (1) and discharge display (4) is arranged.

4. Device according to one of the preceding claims, wherein a

Product container (5) contained in the device or in the device can be inserted, wherein the product container (5) and / or connected to the product container (5) needle (6) relative to the housing along the longitudinal axis of the housing, in particular between a starting position and a puncture position is displaced.

5. Apparatus according to the preceding claim, wherein the product container (5) and / or the needle (6) is coupled to the visual release member (3) such that upon movement from a visual release member (3) and product container (5) and / or needle (6) the other at least partially participates in the movement of the one.

6. Device according to one of the two preceding claims, wherein the product from the product container (5) with a product acting on the piston (7a) can be discharged, and wherein the piston (7a) is so coupled to the discharge display (4) that upon movement of one of the dispensing indicator (4) and piston (7a), the other at least partially participates in the movement of the one.

7. Device according to one of the three preceding claims, wherein the

Visual release member (3) has a first region (3a) which is in the field of view when the product container (5) or the needle (6) is in its initial position.

8. Device according to the preceding claim, wherein the first region (3a) contains information that can be seen through the see-through element (2).

9. Device according to the preceding claim, wherein the information a

Material property of the material of the first area (3 a), a character, an image and / or color information is.

10. Device according to one of the three preceding claims, wherein the first

Area (3a) is transparent or opaque.

11. Device according to one of the four preceding claims, wherein in addition to the first region (3a), a second region (3 b) is arranged, which is in the field of view, when the product container (5) or the needle (6) in the puncture position located.

12. Device according to the preceding claim, wherein by the

See-through element (2) and the second area (3 b) the discharge display (4) is read.

13. Device according to one of the two preceding claims, wherein the second

Region (3b) is proximal to the Sichtfreigabeglied (3) or a window in the visual release member (3).

14. Device according to one of the three preceding claims, wherein the second

Area (3b) is formed of a transparent material, wherein in a transparent first area (3a), the transparent material of the second area (3b) has a different color than the transparent material of the first area (3a).

15. Device according to the preceding claim, wherein the transparent material of the second region (3b) is clear or colorless.

16. Device according to one of the five preceding claims, wherein in

Between the first region (3a) and the second region (3b), an intermediate region (3c) is arranged at least partially in the longitudinal direction of the device when the product container (5) or the needle (6) moves from the starting position into the piercing position Viewing area is located.

17. Device according to the preceding claim, wherein the intermediate region (3 c) has a character, an image, a color information or a material property, is particularly recognizable by the fact that the product container (5) moves.

18. Device according to one of the preceding claims, wherein the

Putty display (4) is coupled to the visual release member (3) that in the Movement of the product container (5) or the needle (6) from the starting position to the puncture position, in particular during a puncture sequence the dispensing indicator (4) participates the movement of the visual release member (3).

19. Device according to one of the preceding claims, wherein a

Elasticity means (14), in particular a propulsion spring is provided, which can move the Sichtfreigabeglied (3) and / or a product container (5), and / or a needle (6) and / or the dispensing indicator (4) in the piercing direction.

20. Device according to one of the preceding claims, wherein the

Pour display (4) in the Einstechposition a product container (3) or a needle (6), or during a Produktausschüttsequenz in the axial direction relative to the Sichtfreigabeglied (3) is movable.

21. Device according to one of the preceding claims, wherein a

Elasticity means (15), in particular a discharge spring is provided, which can drive a driven member (8) and / or a piston rod (7) and / or a piston (7a) in the delivery direction.

22. Device according to one of the preceding claims, wherein the

Pour display (4) has a first region (4a), which may be in the field of view, when the product container (5) is in the puncture position.

23. Device according to the preceding claim, wherein the first region (4a) can be moved at a product discharge from the field of view.

24. Device according to one of the two preceding claims, wherein in addition to the first region (4a), a second region (4b) is arranged, which is located in the field of vision and can be seen when the product from the product container (5) is distributed.

25. Device according to the preceding claim, wherein the first area (4a) and the second area (4b) each contain information, in particular a material property, a drawing, an image and / or color information, wherein the information of the first area (4a ) is different from that of the second region (4b).

26. Device according to one of the two preceding claims, wherein between the first region (4a) and the second region (4b), an intermediate region (4c) is arranged, which is located during the product distribution in the field of view or moved through the field of view.

27. Device according to the preceding claim, wherein the intermediate region (4c) has a character, an image, a color information or a material property, is particularly recognizable by the fact that the product container (5) moves.

28. A method for displaying various states of a device for

Administering an injectable product displaying various information readable by a see-through element (2), the information being information that a product container (5) located in the device is in a home position, information indicating that the device is being read Product container (5) is located in a puncture position and information that the product contained in the product container (5) was distributed product include.

29. The method according to the preceding claim, wherein the device is designed according to one of claims 1 to 27.