EP1949874B1 - Endhülsenbeschichtung zur Stenteinbringung - Google Patents
Endhülsenbeschichtung zur Stenteinbringung Download PDFInfo
- Publication number
- EP1949874B1 EP1949874B1 EP08003235.2A EP08003235A EP1949874B1 EP 1949874 B1 EP1949874 B1 EP 1949874B1 EP 08003235 A EP08003235 A EP 08003235A EP 1949874 B1 EP1949874 B1 EP 1949874B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- stent
- delivery system
- stent delivery
- lubricious
- sleeve
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- 0 Cc(cc1NC)ccc1N* Chemical compound Cc(cc1NC)ccc1N* 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/958—Inflatable balloons for placing stents or stent-grafts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/958—Inflatable balloons for placing stents or stent-grafts
- A61F2002/9583—Means for holding the stent on the balloon, e.g. using protrusions, adhesives or an outer sleeve
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/958—Inflatable balloons for placing stents or stent-grafts
- A61F2002/9583—Means for holding the stent on the balloon, e.g. using protrusions, adhesives or an outer sleeve
- A61F2002/9586—Means for holding the stent on the balloon, e.g. using protrusions, adhesives or an outer sleeve the means being inside the balloon
Definitions
- the patent relates to a delivery system in which a catheter carries on its distal end portion a stent which is held in place around the catheter prior to and during percutaneous delivery by means of one and preferably two end sleeves which have been coated with a lubricious material.
- the lubricious material is added to the sleeve material subsequent to extrusion of the sleeve material but prior to a heat curing step. As a result of the heat curing the lubricious material attains a gel or jellied consistency.
- the stent may be self-expanding, such as a NITINOL shape memory stent, or it may be expandable by means of an expandable portion of the catheter, such as a balloon.
- a stent is a generally cylindrical prosthesis introduced via a catheter into a lumen of a body vessel in a configuration having a generally reduced diameter and then expanded to the diameter of the vessel. In its expanded configuration, the stent supports and reinforces the vessel walls while maintaining the vessel in an open, unobstructed condition.
- Self-expanding and inflation expandable stents are well known and widely available in a variety of designs and configurations.
- Self-expanding stents must be maintained under a contained sheath or sleeve(s) in order to maintain their reduced diameter configuration during delivery of the stent to its deployment site.
- Inflation expandable stents are crimped to their reduced diameter about the delivery catheter, then maneuvered to the deployment site and expanded to the vessel diameter by fluid inflation of a balloon positioned between the stent and the delivery catheter.
- the present invention is particularly concerned with delivery and deployment of inflation expandable stents, although it is generally applicable to self-expanding stents when used with balloon catheters.
- the stent In advancing an inflation expandable stent through a body vessel to the deployment site, there are a number of important considerations.
- the stent must be able to securely maintain its axial position on the delivery catheter, without translocating proximally or distally, and especially without becoming separated from the catheter.
- the stent, particularly any potentially sharp or jagged edges of its distal and proximal ends, must be protected to prevent edge dissection and prevent abrasion and/or reduce trauma of the vessel walls.
- Inflation expandable stent delivery and deployment systems are known which utilize restraining means that overlie the stent during delivery.
- U. S. Patent No.4,950,227 to Savin et al. relates to an inflation expandable stent delivery system in which a sleeve overlaps the distal or proximal margin (or both) of the stent during delivery. During inflation of the stent at the deployment site, the stent margins are freed of the protective sleeve (s).
- U. S. Patent 5,403,341 to Solar relates to a stent delivery and deployment assembly which uses retaining sheaths positioned about opposite ends of the compressed stent.
- the retaining sheaths of Solar are adapted to tear under pressure as the stent is radially expanded, thus releasing the stent from engagement with the sheaths.
- U. S. Patent No. 5,108,416 to Ryan et al. describes a stent introducer system which uses one or two flexible end caps and an annular socket surrounding the balloon to position the stent during introduction to the deployment site.
- This invention provides an improvement over the cited art, by selectively coating or otherwise lubricating, the sleeve subsequent to its extrusion yet prior to heat curing. This is in contrast to prior methods of lubricating the sleeve, such as by incorporating a lubricant additive within the polymeric composition of the sleeve, such as described in U. S. Patent Application No. 09/273,520 ., In addition, the present invention avoids the use of collars, rings or other devices used to secure the sleeves to the catheter by bonding an end of a sleeve to the catheter directly.
- US 5,944,726 A discloses a stent delivery system including a catheter, balloon and sleeves and a silicone fluid between the balloon and the sleeves.
- US 5,295,978 A discloses biocompatible polymeric complexes having utility in medical applications, some of which can render the surface lubricious when exposed to aqueous fluids.
- EP-A-688 545 discloses a stent delivery system with a non-silicone based lubricant on the outside and/or inside of the catheter sheath.
- the sleeves are positioned around the catheter with one end portion of each sleeve connected thereto.
- the other end of each sleeve overlaps an opposite end portion of the stent to hold it in place on the catheter in a contracted condition.
- the sleeves are elastomeric in nature so as to stretch and release the stent when it is expanded for delivery.
- a viscous jelly-like lubricant material is provided on the inside surface of the sleeve between the sleeve and the balloon on the catheter, the outside surface of the sleeve, or on both.
- a fluid or dry lubricant is coated onto the sleeve material after it has been extruded.
- the coated material is cured.
- the curing process leads to a gelling of the lubricant resulting in the presently desired lubricious yet viscous lubricant material which offers resistance to flow, herein termed a "lubricious gel" coating.
- Dry lubricants also find utility in the present invention, and may used alone, or in combination with a fluid lubricant.
- dry lubricants useful herein include those described as solid lamellar form lubricants such as graphite and modified tungsten disulfides such as those sold under the tradename of DICRONITE® available from Dicronite Dry Lube.
- PARYLENE® Another dry lubricant which may be applied using vapor deposition techniques is sold under the tradename of PARYLENE®. These materials are high molecular weight hydrocarbon materials available from Advanced Coating in Collinso Cucamonga, CA. PARYLENE® materials are referred to as di-para-xylylene (dimers) materials and are available in several forms including the following:
- outside surface of the respective sleeves may be coated as well as the inner surface, or only specific portions of the outer and/or inner surfaces of the sleeves are coated.
- the outer surface of the sleeves are coated with a lubricious hydrophilic coating.
- Non-crosslinkable hydrophilic lubricants which may be used with the present invention include: polyalkylene glycols; alkoxy polyalkylene; copolymers of methyl vinyl ether and maleic acid; pyrrolidones including poly(vinylpyrrolidone); acryl amides including poly(N-alkylacrylamide); poly(acrylic acid); poly(vinyl alcohol); poly(ethyleneimine); poly amides; methyl cellulose; hepartin; dextran; modified dextran; chondroitin sulfate; lecithin, etc.
- These polymers typically contain a hydrophilic group such as: -OH, -CONH 2 , -COOH, -NH 2 , -COO-, -SO 3 , -NR 3 + , etc.
- crosslinkable hydrophilic lubricants which may alternatively be utilized with the present invention include: esterified polymers, salts, amides, anhydrides, halides, ethers, hydrolyzates, acetals, formals, alkylols, quaternary polymers, diazos, hydrazides, sulfonates, nitrates and ion complexes.
- Fig. 1 shows an embodiment of the present invention wherein a catheter generally designated 10 has an expandable portion or balloon 12.
- the expandable portion may be an inherent part of the catheter, as shown, or alternatively may be a separate balloon which is affixed to the catheter in any of the manners which may be known to one of ordinary skill in the art.
- Disposed about balloon 12 is a stent 14 as shown.
- Stent 14 may be any stent type capable of being delivered by a stent delivery catheter, such stents may be self-expanding or balloon expandable.
- Attached to the catheter 10 are a pair of sleeves 16,18.
- the sleeves each include a first portion 16a, 18a.
- first sleeve portions 16a, 18a overlay the ends of balloon 12 as well as the ends of stent 14 as shown.
- Sleeves 16 and 18 also include respective second portions 16b and 18b.
- second sleeve portions 16b, 18b are fixedly attached to catheter 10.
- the second sleeve portions may be attached to the catheter utilizing any method of attachment known.
- Such methods of attachment may include, but are not limited to: bonding or welding the sleeves to the catheter surface, applying an adhesive between the catheter and sleeve surface, or employing a mechanical attachment device such as a retaining ring or collar as is well known in the art.
- the sleeves each have a thickness within the range of 25,4 ⁇ m to 152,4 ⁇ m (0.0010 to 0.0060 inches).
- the present invention avoids the problems mentioned above, by placing a coating of lubricious gel 30 on the interior and exterior surfaces of sleeves 16 and 18 after the sleeve material has been extruded.
- a suitable fluid lubricant is added to the sleeve material and then heat cured. Heat curing the fluid lubricant coating allows the coating to gel as is desired.
- the resulting lubricious coating has a gel-like state as defined herein above, and does not wick or have a tendency to migrate off of the sleeve as prior liquid silicone based lubricant coatings does.
- the lubricious coating may be comprised of either hydrophobic or hydrophilic compounds.
- lubricious coating 30 is shown in the various drawings with a highly exaggerated thickness.
- lubricious coating 30 is preferably a thin layer.
- the gelled lubricious coating 30 is a layer less than 2,54 ⁇ m (0.0001 inches) in thickness.
- the physical characteristics of the gelled lubricious coating are such that migration of the coating onto the surfaces of the stent is prevented, unlike the prior slip coatings described above.
- the present stent deployment system has reduced parameters for crimping the stent to the balloon, which provides for a crimping process which is much more balloon friendly.
- Lubricious coating 30 assists in deployment of stent 14 by allowing the ends of balloon 12 and stent 14 to slide more readily away from the sleeves when balloon 12 is inflated, as seen in Fig. 2 . Once the ends of stent 14 are no longer overlaid by sleeves 16 and 18 the stent is allowed to fully expand.
- sleeves 16 and 18 may have a lubricious coating on both their inside surfaces as well as their outside surfaces.
- a lubricious coating on the outside surfaces may provide improved trackability and movement of the catheter in a body lumen.
- a lubricious coating on the outside surface of the sleeves may assist in the retraction of such a catheter sheath by reducing the amount of resistance the sheath must overcome in order to be retracted from the stent mounting region.
- the outside lubricious coating may reduce the likelihood of the sheath hooking or pulling on the sleeves or stent as it is pulled back.
- a further preferred embodiment of the present invention it may be desirable to coat only the inside surfaces of the sleeves. As shown in Fig. 3 , only the inside surface of sleeves 16 and 18 are coated with lubricious coating 30.
- lubricious coatings may interfere with the attachment of the sleeves to the catheter. In such an instance, it may be desirable or necessary to coat only specific portions of the sleeves. More specifically, in order to ensure proper securement of second sleeve portions 16b and 18b to catheter 10 it may be desirable or necessary to avoid coating the second sleeve portions, as shown in Fig. 4 .
- the benefits provided by lubricious coating 30 are substantially maintained in this instance by coating only the inside surface of first sleeve portions 16a and 16b, thereby ensuring that the ends of the stent and balloon may be readily withdrawn from under the sleeves when the balloon is inflated.
- Weld 32 may be a lap weld, a butt weld, an adhesive or any other means of connection which may be known to one of ordinary skill in the art.
- the sleeves may have a tri-layer construction such as shown in Figs. 6 and 7 .
- the sleeves may be comprised of an inner layer 40 which is an inherently lubricous polymer such as polytetrafluoroethylene (PTFE), high density polyethylene (HDPE), acetal resins such as those available from the Dupont corporation such as DELTRIN ® or other suitable polymer types.
- PTFE polytetrafluoroethylene
- HDPE high density polyethylene
- acetal resins such as those available from the Dupont corporation such as DELTRIN ® or other suitable polymer types.
- Figs. 6 and 7 in order to show two potential embodiments of sleeves which may include the tri-layer construction described above, the sleeves are shown in an exaggerated scale. Furthermore, respective Figs. 6 and 7 each show only a single sleeve 18, sleeve 16 is a left-handed mirror image of sleeve 18 as shown.
- inner layer 40 may extend through out the length of a sleeve 18 or in an alternative embodiment shown in Fig. 7 , may be confined to only a portion of the sleeve such as the first sleeve portions 16a and 18a. Opposite the inner layer 40 is outer layer 44.
- Outer layer 44 is composed of any polymer material which can be used in any of the embodiments of the present invention already described herein, preferably having elastomer properties as well as heat shrinkable properties.
- the lubricious inner layer 40 and the outer polymer layer 44 are joined by an intermediate layer 42.
- the intermediate layer or third is composed of material which is characterized as being capable of bonding to the inner lubricous polymer material on one surface, and the outer sleeve polymer material on the other.
- the intermediate layer is composed of PLEXAR ® 380, thermoplastic polymers including polypropylene, polyurethane or other similar materials.
- first sleeve portion 18a to the second sleeve portion 18b, with a weld 32 or other method of attachment as described as described in relation to Fig. 5 above.
- the lubricious coating 30 is provided on the outer surface of the sleeves 16 and 18, it is a hydrophilic coating.
- the sleeves 16 and 18 are preferably coated without coating the stent or balloon structures themselves.
- the coating may be applied either by dipping or by brushing. Dipping, however, typically involves coating both the inner and outer surfaces of the sleeves 16 and 18 as shown in Fig. 1 .
- the coating typically requires drying or curing time which time may be decreased by the addition of a heating source.
- the hydrophilic coating may be applied at a thickness of about 0.2 to about 20 ⁇ m.
- the water soluble lubricants useful herein include polyalkylene glycols, alkoxy polyalkylene glycols, homopolymers and copolymers of (meth) acrylic acid, copolymers of methylvinyl ether and maleic acid, poly(vinylpyrrolidone) homopolymers, copolymers of vinyl pyrrolidone, poly(N-alkylacrylamide), poly(vinyl alcohol), poly(ethyleneimine), polyamides, methyl cellulose, carboxymethylcellulose, polyvinylsulfonic acid, heparin, dextran, modified dextran, chondroitin sulphate and lecithin.
- the polymers are typically chain-structured, non-crosslinked and water soluble having a hydrophilic group such as -OH, -CONH 2 , -COOH, -NH 2 , -COO-, -SO 3 , -NR 3 + and so forth where R is alkyl or hydrogen.
- These water soluble polymers are typically chain-structured, non-crosslinked polymers having a hydrophilic group such as -OH, - CONH 2 , -COOH, -NH 2 , -COO-, SO 3 , AND NR 3 + , where R is alkyl or hydrogen.
- Natural hydrophilic polymers may also be utilized such as carboxymethyl cellulose, methyl cellulose, hydroxyethyl cellulose and hydroxypropyl cellulose, heparin, dextran, modified dextran and chondroitin sulphate.
- Synthetic hydrophilic polymers include the polyalkylene glycols and polyoxyalkylene glycols such as polyethylene oxide, polyethylene oxide/polypropylene oxide copolymers and methoxypolyethylene oxide; copolymers of maleic anhydride including methyl vinyl ether-maleic anhydride copolymers; pyrrolidones including poly(vinylpyrrolidone); acryl amides including poly(N-alkylacrylamide); poly(acrylic acid); poly(carboxylic acids); poly(vinyl alcohol); poly(ethyleneimine); water soluble nylons; polyurethanes; and so forth.
- Derivatives of any of these polymers may be utilized providing that enough of the basic structure of the polymers above that provides water sensitivity, solubility or dispersibility is retained allowing the polymer to uptake enough water to swell or partially dissolve enough upon exposure to moisture to provide lubricity in such a way to reduce frictional forces between the surface it is coated on and another surface such as tissue, metal or polymeric surfaces.
- Water insoluble derivatives may be employed as long as they have the freedom in the molecular chain and can be hydrated.
- Examples include esterified polymers, salts, amides, anhydrides, halides, ethers, hydrolyzates, acetals, formals, alkylols, quaternary polymers, diazos, hydrazides, sulfonates, nitrates, and ion complexes which are obtained by condensation, addition, substitution, oxidation, or reduction reactions of the above-mentioned water soluble polymers.
- Also used are polymers crosslinked with substances having more than one reactive functional group such as diazonium, azide, isocyanate, acid chloride, acid anhydride, imino carbonate, amino, carboxyl, epoxy, hydroxyl, and aldehyde groups.
- hydrophilic polymer useful herein include those polymers that have the ability to dissolve or swell in an aqueous environment, often referred to as "hydrogels.” These polymers are capable of manifesting lubricity while in a wet state, and when hydrated, exhibit low frictional forces in humoral fluids such as saliva, digestive fluids and blood, as well as in saline solution and water.
- Such hydrogel compounds include polyethylene oxides (optionally linked to the substrate surface by interpenetrating network, IPN, with poly(meth)acrylate polymers or copolymers; copolymers of maleic anhydride; (meth)acrylamide polymers and copolymers; (meth)acrylic acid copolymers; poly(vinyl pyrrolidone) and blends or interpolymers with polyurethanes; and polysaccharides.
- IPN interpenetrating network
- polymeric materials which hydrogels may comprise include polyalkylene glycols, alkoxy polyalkylene glycols, copolymers of methylvinyl ether and maleic acid, poly(N-alkylacrylamide), poly(acrylic acid), poly(vinyl alcohol), poly(ethyleneimine), polyamides, methyl cellulose, carboxymethyl cellulose, polyvinyl sulfonic acid, heparin, dextran, modified dextran and chondroitin sulphate.
- a hydrogel of polyethylene oxide may be captured in an interpenetrating crosslinked acrylic polymer network by polymerizing a mixture of an acrylic monomer composition comprising a monomer having plural (meth)acrylate groups and polyethylene oxide, thereby providing a hydrogel coating.
- Copolymers with vinyl groups, acrylic acid, methacrylic acid, fumaric acid, maleic acid, maleic anhydride, diene compounds, or other polymerizable ethylenically unsaturated compounds are another particular group of polymers which find utility herein.
- the acids may be optionally be neutralized.
- copolymers based on maleic anhydride examples include poly(ethylene-maleic anhydride) sold by Aldrich Chemical Co. or maleic anhydridemethyl vinyl ether copolymers such as Gantrez ® AN 169 sold by G.A.F. Corporation.
- hydrophilic coatings which find particular utility herein include the polyethylene oxides, polyacrylic acids and polyvinylpyrrolidones.
- the hydrophilic polymers of the present invention may be utilized in any combination to more narrowly tailor the resultant composition to the application. Some of the hydrophilic polymers of the present invention exhibit less flexibility than others. For instance, the flexibility of the hydrogels found in the previous paragraph above, may be improved by the addition of polyethylene oxide/polypropylene oxide copolymers, especially block copolymers, poly(vinyl pyrrolidone), polyvinyl alcohol, and so forth.
- the present invention also contemplates the use of slip additives or antiblock agents to the hydrophilic coatings of the present invention, particularly in those embodiments in which the outer surface of the sleeves are coated with a lubricious hydrophilic coating.
- the coating compositions of the present invention may be coated out of a solvent or a cosolvent mixture using any conventional coating techniques such as dipping, spraying, brushing, and so forth.
- hydrophilic coatings have been discussed in relation to an embodiment directed more toward coating the outer surface of sleeves, they may also be used to coat the inner surface of the sleeves, or both.
- Useful solvents include alcohols, aliphatic hydrocarbons, aromatic hydrocarbons, chlorinated solvents, esters, glycols, glycol ethers, ketones, and so forth.
- Polar solvents include alcohols, glycols, water and so forth. Specific examples include ethanol, methanol, isopropanol, stearyl alcohol, ethylene glycol, propylene glycol, glycerin, water and so forth.
- Non-polar solvents include aliphatic hydrocarbons such as heptane and hexane; aromatic hydrocarbons such as toluene and xylene; chlorinated hydrocarbons such as perchloroethylene, methylene chloride, chloroform, carbon tetrachloride, 1,1,1-trichloroethane; fluorocarbons; mineral spirits and so forth.
- the preferable solvents are more polar and preferably include the alcohols such as isopropyl alcohol or isopropanol and water and mixtures thereof.
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Claims (18)
- Stentzuführsystem, aufweisend einen Stentzuführkatheter (10), der mit mindestens einer Stenthaltehülse (16, 18) ausgestattet ist, wobei die mindestens eine Stenthaltehülse (16, 18) eine Innenfläche und eine Außenfläche aufweist, wobei die Stenthaltehülse (16, 18) eine Gleitbeschichtung an mindestens einem Abschnitt der Innenfläche und/oder Außenfläche aufweist, dadurch gekennzeichnet, dass die Gleitbeschichtung ein nicht auf Silikon basierendes Gleitmittel ist, wobei das Gleitmittel durch Wärme zu einem Gel (30) ausgehärtet wird.
- Stentzuführsystem nach Anspruch 1, wobei die mindestens eine Stenthaltehülse (16, 18) aus einem Material gebildet ist, das erst extrudiert und anschließend ausgehärtet wird, wobei das Material nach dem Extrudieren aber vor dem Wärmehärten zumindest teilweise mit einer Gleitsubstanz beschichtet wird.
- Stentzuführsystem nach Anspruch 1, wobei mindestens eine Stenthaltehülse (16, 18) aus einem extrudierten Polymerwerkstoff besteht.
- Stentzuführsystem nach Anspruch 1, wobei mindestens ein Abschnitt der Außenfläche der Hülse (16, 18) mit einer Gleitbeschichtung beschichtet ist.
- Stentzuführsystem nach Anspruch 1, wobei mindestens ein Abschnitt der Innenfläche der Hülse (16, 18) mit einer Gleitbeschichtung beschichtet ist.
- Stentzuführsystem nach Anspruch 1, wobei die Gleitbeschichtung hydrophil ist.
- Stentzuführsystem nach Anspruch 1, wobei die Gleitbeschichtung mindestens eine Verbindung aufweist, die aus Hydrogelen, Copolymeren von Polyalkylenoxiden, Homopolymeren oder Copolymeren von Vinylpyrrolidon, Copolymeren von mindestens einer polymersisierbaren ethylenisch ungesättigten Verbindung und Gemischen daraus besteht.
- Stentzuführsystem nach Anspruch 7, wobei das Hydrogel ein Hydrogel aus Polyethylenoxid ist, das in einem vernetzten interpenetrierenden Acrylpolymer-Netzwerk, gefangen ist, in dem ein Gemisch aus einer Acrylmonomerzusammensetzung, die ein Monomer umfasst, das mehrere Methacrylatgruppen aufweist, und Polyethylenoxid polymerisiert wird, wodurch eine Hydrogelbeschichtung geschaffen wird.
- Stentzuführsystem nach Anspruch 1, wobei die Gleitbeschichtung mindestens eine Polycarbonsäure aufweist.
- Stentzuführsystem nach Anspruch 7, wobei das Copolymer ein Copolymer von mindestens einem Element ist, das aus Maleinsäure, Fumarsäure, (Meth)Acrylsäure, Maleinsäureanhydrid und Gemischen daraus ausgewählt ist.
- Stentzuführsystem nach Anspruch 10, wobei das Maleinsäureanhydrid-Copolymer aus Polyethylen-Maleinsäureanhydrid-Copolymeren und Maleinsäureanhydrid-Methylvinylether-Copolymeren ausgewählt ist.
- Stentzuführsystem nach Anspruch 1, wobei die Gleitbeschichtung aus einem Polymersystem besteht, das eine Härtung oder Trocknung erfordert.
- Stentzuführsystem nach Anspruch 1, wobei die Gleitbeschichtung ein trockenes Gleitmaterial umfasst.
- Stentzuführsystem nach Anspruch 1, wobei die Gleitbeschichtung ein Gleitgel (30) ist.
- Stentzuführsystem nach Anspruch 1, wobei die Innenfläche ferner dadurch gekennzeichnet ist, dass sie einen ersten Abschnitt und einen zweiten Abschnitt aufweist, wobei der erste Abschnitt der Abschnitt der Innenfläche ist, der auf dem dehnbaren Abschnitt des Katheters über dem Stent liegt, wobei der zweite Abschnitt der Abschnitt der Innenfläche ist, der am Katheter befestigt ist, wobei zumindest der erste Abschnitt mit dem Gleitmaterial beschichtet ist.
- Stentzuführsystem nach Anspruch 1, wobei die mindestens eine Hülse (16, 18) ferner dadurch gekennzeichnet ist, dass sie einen ersten Abschnitt (16a, 18a) und einen zweiten Abschnitt (16b, 18b) aufweist, wobei der erste Abschnitt (16a, 18a) der Abschnitt der mindestens einen Hülse (16, 18) ist, der auf dem dehnbaren Abschnitt des Katheters (10) über dem Stent liegt, wobei der zweite Abschnitt (16b, 18b) der Abschnitt der mindestens einen Hülse (16, 18) ist, der am Katheter (10) befestigt ist, wobei der erste Abschnitt (16a, 18a) aus einem extrudierten Polymer in Verbindung mit dem Gleitgel (30) besteht, wobei kein Gleitgel (30) in der Zusammensetzung des zweiten Abschnitts (16b, 18b) vorhanden ist.
- Stentzuführsystem nach Anspruch 16, wobei der erste Abschnitt (16a, 18a) und der zweite Abschnitt (16b, 18b) durch ein Verfahren miteinander verbunden sind, das aus Kleben, Verbinden mit einem Laser und Schweißen ausgewählt ist.
- Stentzuführsystem nach Anspruch 1, wobei das Gleitmittel ein vernetzbares Gleitmittel aufweist, wobei das vernetzbare Gleitmittel mindestens ein Element aus der Gruppe bestehend aus veresterten Polymeren, Salzen, Amiden, Anhydriden, Halogeniden, Ethern, Hydrolysaten, Acetalen, Formaldehydacetale (engl. formals), Alkanole, quartären Polymeren, Diazoverbindungen (engl. diazos), Hydraziden, Sulfonaten, Nitraten, Ionenkomplexen, aufweist.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/427,805 US6331186B1 (en) | 1999-03-22 | 1999-10-27 | End sleeve coating for stent delivery |
EP00989735A EP1223892B1 (de) | 1999-10-27 | 2000-10-27 | Endhülse mit beschichtung für ein stentanbringungssystem |
Related Parent Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00989735A Division EP1223892B1 (de) | 1999-10-27 | 2000-10-27 | Endhülse mit beschichtung für ein stentanbringungssystem |
EP00989735.6 Division | 2000-10-27 |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1949874A2 EP1949874A2 (de) | 2008-07-30 |
EP1949874A3 EP1949874A3 (de) | 2011-03-16 |
EP1949874B1 true EP1949874B1 (de) | 2015-08-12 |
Family
ID=23696362
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00989735A Expired - Lifetime EP1223892B1 (de) | 1999-10-27 | 2000-10-27 | Endhülse mit beschichtung für ein stentanbringungssystem |
EP08003235.2A Expired - Lifetime EP1949874B1 (de) | 1999-10-27 | 2000-10-27 | Endhülsenbeschichtung zur Stenteinbringung |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00989735A Expired - Lifetime EP1223892B1 (de) | 1999-10-27 | 2000-10-27 | Endhülse mit beschichtung für ein stentanbringungssystem |
Country Status (8)
Country | Link |
---|---|
US (1) | US6331186B1 (de) |
EP (2) | EP1223892B1 (de) |
JP (1) | JP4663945B2 (de) |
AT (1) | ATE393606T1 (de) |
CA (1) | CA2388542A1 (de) |
DE (1) | DE60038742T2 (de) |
ES (1) | ES2303819T3 (de) |
WO (1) | WO2001034219A2 (de) |
Families Citing this family (84)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7238197B2 (en) | 2000-05-30 | 2007-07-03 | Devax, Inc. | Endoprosthesis deployment system for treating vascular bifurcations |
US8728143B2 (en) | 1996-06-06 | 2014-05-20 | Biosensors International Group, Ltd. | Endoprosthesis deployment system for treating vascular bifurcations |
US7686846B2 (en) | 1996-06-06 | 2010-03-30 | Devax, Inc. | Bifurcation stent and method of positioning in a body lumen |
EP1117341B1 (de) | 1998-09-30 | 2004-12-29 | Bard Peripheral Vascular, Inc. | Austragungsvorrichtung für implantierbare stents |
US6443980B1 (en) | 1999-03-22 | 2002-09-03 | Scimed Life Systems, Inc. | End sleeve coating for stent delivery |
US6533806B1 (en) * | 1999-10-01 | 2003-03-18 | Scimed Life Systems, Inc. | Balloon yielded delivery system and endovascular graft design for easy deployment |
US6562061B1 (en) * | 2000-02-22 | 2003-05-13 | Scimed Life Systems, Inc. | Stent delivery balloon with securement structure |
US6860960B1 (en) * | 2000-09-05 | 2005-03-01 | Scimed Life Systems, Inc. | Method of applying a laser beam around the circumference of a catheter |
US6607552B1 (en) * | 2000-09-18 | 2003-08-19 | Scimed Life Systems, Inc. | Rolling socks |
US6554841B1 (en) * | 2000-09-22 | 2003-04-29 | Scimed Life Systems, Inc. | Striped sleeve for stent delivery |
US20050226993A1 (en) * | 2000-10-03 | 2005-10-13 | Nawrocki Jesse G | Medical devices having durable and lubricious polymeric coating |
US6761733B2 (en) | 2001-04-11 | 2004-07-13 | Trivascular, Inc. | Delivery system and method for bifurcated endovascular graft |
US6733521B2 (en) | 2001-04-11 | 2004-05-11 | Trivascular, Inc. | Delivery system and method for endovascular graft |
US20020161376A1 (en) * | 2001-04-27 | 2002-10-31 | Barry James J. | Method and system for delivery of coated implants |
AU2002325298A1 (en) | 2001-07-06 | 2003-01-21 | Angiomed Gmbh And Co. Medizintechnik Kg | Delivery system having a rapid pusher assembly for self-expanding stent, and stent exchange configuration |
GB0123633D0 (en) | 2001-10-02 | 2001-11-21 | Angiomed Ag | Stent delivery system |
US20030077310A1 (en) | 2001-10-22 | 2003-04-24 | Chandrashekhar Pathak | Stent coatings containing HMG-CoA reductase inhibitors |
US20100016943A1 (en) | 2001-12-20 | 2010-01-21 | Trivascular2, Inc. | Method of delivering advanced endovascular graft |
US7169170B2 (en) * | 2002-02-22 | 2007-01-30 | Cordis Corporation | Self-expanding stent delivery system |
DE10233968C1 (de) * | 2002-07-25 | 2003-12-18 | Uponor Innovation Ab | Presshülsenbeschichtung |
DE60201905T2 (de) * | 2002-09-09 | 2005-11-10 | Abbott Laboratories Vascular Enterprises Ltd. | System zum Einführen eines selbstexpandierenden Stents |
US7041088B2 (en) * | 2002-10-11 | 2006-05-09 | Ethicon, Inc. | Medical devices having durable and lubricious polymeric coating |
WO2004041126A1 (en) | 2002-11-08 | 2004-05-21 | Jacques Seguin | Endoprosthesis for vascular bifurcation |
US20040111144A1 (en) * | 2002-12-06 | 2004-06-10 | Lawin Laurie R. | Barriers for polymeric coatings |
WO2004062458A2 (en) | 2003-01-15 | 2004-07-29 | Angiomed Gmbh & C0. Medizintechnik Kg | Trans-luminal surgical device |
US6859986B2 (en) * | 2003-02-20 | 2005-03-01 | Cordis Corporation | Method system for loading a self-expanding stent |
US8083791B2 (en) | 2003-04-14 | 2011-12-27 | Tryton Medical, Inc. | Method of treating a lumenal bifurcation |
US7731747B2 (en) | 2003-04-14 | 2010-06-08 | Tryton Medical, Inc. | Vascular bifurcation prosthesis with multiple thin fronds |
US7481834B2 (en) | 2003-04-14 | 2009-01-27 | Tryton Medical, Inc. | Stent for placement at luminal os |
US8109987B2 (en) | 2003-04-14 | 2012-02-07 | Tryton Medical, Inc. | Method of treating a lumenal bifurcation |
US7972372B2 (en) | 2003-04-14 | 2011-07-05 | Tryton Medical, Inc. | Kit for treating vascular bifurcations |
US7758630B2 (en) | 2003-04-14 | 2010-07-20 | Tryton Medical, Inc. | Helical ostium support for treating vascular bifurcations |
US7717953B2 (en) | 2004-10-13 | 2010-05-18 | Tryton Medical, Inc. | Delivery system for placement of prosthesis at luminal OS |
US20040215314A1 (en) * | 2003-04-25 | 2004-10-28 | Kantor John D. | Stent deployment assembly with collars for drug-eluting stent |
KR101194688B1 (ko) | 2003-05-23 | 2012-10-29 | 가부시키가이샤 교토 이료 세케이 | 스텐트 공급장치 |
US7604621B2 (en) | 2003-07-30 | 2009-10-20 | Boston Scientific Scimed, Inc. | Bifurcated stent delivery system |
US7225518B2 (en) | 2004-02-23 | 2007-06-05 | Boston Scientific Scimed, Inc. | Apparatus for crimping a stent assembly |
US8137397B2 (en) * | 2004-02-26 | 2012-03-20 | Boston Scientific Scimed, Inc. | Medical devices |
US7285130B2 (en) * | 2004-04-27 | 2007-10-23 | Boston Scientific Scimed, Inc. | Stent delivery system |
US20050278011A1 (en) | 2004-06-10 | 2005-12-15 | Peckham John E | Stent delivery system |
US7955370B2 (en) * | 2004-08-06 | 2011-06-07 | Boston Scientific Scimed, Inc. | Stent delivery system |
US7393358B2 (en) * | 2004-08-17 | 2008-07-01 | Boston Scientific Scimed, Inc. | Stent delivery system |
JP2008510587A (ja) * | 2004-08-26 | 2008-04-10 | クック インコーポレイテッド | 制御された摩擦特性を有する送出し装置 |
US20060083770A1 (en) * | 2004-10-15 | 2006-04-20 | Specialty Coating Systems, Inc. | Medical devices and methods of preparation and use |
US7820937B2 (en) * | 2004-10-27 | 2010-10-26 | Boston Scientific Scimed, Inc. | Method of applying one or more electromagnetic beams to form a fusion bond on a workpiece such as a medical device |
US7632296B2 (en) * | 2005-03-03 | 2009-12-15 | Boston Scientific Scimed, Inc. | Rolling membrane with hydraulic recapture means for self expanding stent |
CA2608160C (en) | 2005-05-09 | 2013-12-03 | Jurgen Dorn | Implant delivery device |
US20060265040A1 (en) * | 2005-05-17 | 2006-11-23 | Medtronic Vascular, Inc. | Stent delivery and retention apparatus |
US7927362B2 (en) * | 2005-07-21 | 2011-04-19 | Boston Scientific Scimed, Inc. | Laser ablated elastomer sheath profiles to enables stent securement |
US8038704B2 (en) * | 2005-07-27 | 2011-10-18 | Paul S. Sherburne | Stent and other objects removal from a body |
CN101437571B (zh) | 2005-10-13 | 2013-01-02 | 斯恩蒂斯有限公司 | 载药包装物 |
US8926679B2 (en) | 2006-03-03 | 2015-01-06 | Boston Scientific Scimed, Inc. | Bifurcated stent system balloon folds |
US20070260304A1 (en) * | 2006-05-02 | 2007-11-08 | Daniel Gregorich | Bifurcated stent with minimally circumferentially projected side branch |
US8439961B2 (en) * | 2006-07-31 | 2013-05-14 | Boston Scientific Scimed, Inc. | Stent retaining mechanisms |
US8226701B2 (en) | 2007-09-26 | 2012-07-24 | Trivascular, Inc. | Stent and delivery system for deployment thereof |
US8066755B2 (en) | 2007-09-26 | 2011-11-29 | Trivascular, Inc. | System and method of pivoted stent deployment |
US8663309B2 (en) | 2007-09-26 | 2014-03-04 | Trivascular, Inc. | Asymmetric stent apparatus and method |
CN101917929A (zh) | 2007-10-04 | 2010-12-15 | 特里瓦斯库拉尔公司 | 用于低型面经皮递送的模块化脉管移植物 |
US8083789B2 (en) | 2007-11-16 | 2011-12-27 | Trivascular, Inc. | Securement assembly and method for expandable endovascular device |
US8328861B2 (en) | 2007-11-16 | 2012-12-11 | Trivascular, Inc. | Delivery system and method for bifurcated graft |
WO2009088953A2 (en) | 2007-12-31 | 2009-07-16 | Boston Scientific Scimed Inc. | Bifurcation stent delivery system and methods |
WO2009140214A1 (en) * | 2008-05-10 | 2009-11-19 | Orbusneich Medical, Inc. | Sleeves for positioning a stent on a delivery balloon cathether system |
US8333003B2 (en) | 2008-05-19 | 2012-12-18 | Boston Scientific Scimed, Inc. | Bifurcation stent crimping systems and methods |
US8377108B2 (en) | 2008-06-02 | 2013-02-19 | Boston Scientific Scimed, Inc. | Staggered two balloon bifurcation catheter assembly and methods |
GB0810749D0 (en) | 2008-06-11 | 2008-07-16 | Angiomed Ag | Catherter delivery device |
US9750625B2 (en) * | 2008-06-11 | 2017-09-05 | C.R. Bard, Inc. | Catheter delivery device |
WO2010111446A2 (en) * | 2009-03-25 | 2010-09-30 | Svelte Medical Systems, Inc. | Balloon delivery apparatus and method for using and manufacturing the same |
CN106137479B (zh) * | 2009-05-14 | 2017-12-05 | 奥巴斯尼茨医学公司 | 具有多边形过渡区的自膨式支架 |
US8382818B2 (en) | 2009-07-02 | 2013-02-26 | Tryton Medical, Inc. | Ostium support for treating vascular bifurcations |
JP5412220B2 (ja) * | 2009-09-11 | 2014-02-12 | 花王株式会社 | 有機酸含有造粒物 |
US9931232B2 (en) | 2010-10-21 | 2018-04-03 | Boston Scientific Scimed, Inc. | Stent delivery system |
EP2642946B1 (de) | 2010-11-24 | 2023-08-16 | Poseidon Medical Inc. | Stütze zur behandlung von gefässverzweigungen |
TWI590843B (zh) | 2011-12-28 | 2017-07-11 | 信迪思有限公司 | 膜及其製造方法 |
US8992595B2 (en) | 2012-04-04 | 2015-03-31 | Trivascular, Inc. | Durable stent graft with tapered struts and stable delivery methods and devices |
US9498363B2 (en) | 2012-04-06 | 2016-11-22 | Trivascular, Inc. | Delivery catheter for endovascular device |
US10500077B2 (en) | 2012-04-26 | 2019-12-10 | Poseidon Medical Inc. | Support for treating vascular bifurcations |
US9498249B2 (en) * | 2012-11-21 | 2016-11-22 | P Tech, Llc | Expandable access systems and methods |
US9980837B2 (en) | 2013-03-15 | 2018-05-29 | Boston Scientific Scimed, Inc. | Delivery device for partially unconstrained endoprosthesis |
EP3010560B1 (de) | 2013-06-21 | 2020-01-01 | DePuy Synthes Products, Inc. | Folien und verfahren zur herstellung |
CN107787211B (zh) | 2015-05-27 | 2020-12-08 | 特里瓦斯库拉尔公司 | 球囊辅助的腔内假体部署 |
US10792477B2 (en) | 2016-02-08 | 2020-10-06 | Orbusneich Medical Pte. Ltd. | Drug eluting balloon |
EP3413964A4 (de) | 2016-02-08 | 2019-12-04 | Orbusneich Medical Pte. Ltd | Arzneimitteleluierender ballon |
BR112020014547B1 (pt) | 2018-02-20 | 2023-11-07 | Terumo Kabushiki Kaisha | Dispositivo médico |
US20210338425A1 (en) * | 2020-04-30 | 2021-11-04 | Cephea Valve Technologies, Inc. | Catheter Lumen Lubricant |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0688545A1 (de) * | 1994-06-17 | 1995-12-27 | Terumo Kabushiki Kaisha | Dauerstent und Verfahren zu seiner Herstellung |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4950227A (en) * | 1988-11-07 | 1990-08-21 | Boston Scientific Corporation | Stent delivery system |
US5108416A (en) | 1990-02-13 | 1992-04-28 | C. R. Bard, Inc. | Stent introducer system |
US5160790A (en) * | 1990-11-01 | 1992-11-03 | C. R. Bard, Inc. | Lubricious hydrogel coatings |
US5295978A (en) | 1990-12-28 | 1994-03-22 | Union Carbide Chemicals & Plastics Technology Corporation | Biocompatible hydrophilic complexes and process for preparation and use |
US5403341A (en) | 1994-01-24 | 1995-04-04 | Solar; Ronald J. | Parallel flow endovascular stent and deployment apparatus therefore |
US5733303A (en) | 1994-03-17 | 1998-03-31 | Medinol Ltd. | Flexible expandable stent |
EP0788332B1 (de) * | 1994-10-27 | 2000-11-08 | Boston Scientific Limited | Instrument zum anbringen eines stents |
US5556414A (en) * | 1995-03-08 | 1996-09-17 | Wayne State University | Composite intraluminal graft |
IT1280249B1 (it) | 1995-08-03 | 1998-01-05 | Marposs Spa | Comparatore a tampone per il controllo di parti a simmetria di rotazione |
US5843158A (en) * | 1996-01-05 | 1998-12-01 | Medtronic, Inc. | Limited expansion endoluminal prostheses and methods for their use |
US5800517A (en) * | 1996-08-19 | 1998-09-01 | Scimed Life Systems, Inc. | Stent delivery system with storage sleeve |
US5944726A (en) | 1996-08-23 | 1999-08-31 | Scimed Life Systems, Inc. | Stent delivery system having stent securement means |
US6010521A (en) * | 1997-11-25 | 2000-01-04 | Advanced Cardiovasular Systems, Inc. | Catheter member with bondable layer |
US6160032A (en) * | 1998-09-30 | 2000-12-12 | Medtronic Ave, Inc. | Biocompatible coating composition |
US6221097B1 (en) | 1999-03-22 | 2001-04-24 | Scimed Life System, Inc. | Lubricated sleeve material for stent delivery |
-
1999
- 1999-10-27 US US09/427,805 patent/US6331186B1/en not_active Expired - Fee Related
-
2000
- 2000-10-27 JP JP2001536214A patent/JP4663945B2/ja not_active Expired - Fee Related
- 2000-10-27 EP EP00989735A patent/EP1223892B1/de not_active Expired - Lifetime
- 2000-10-27 AT AT00989735T patent/ATE393606T1/de not_active IP Right Cessation
- 2000-10-27 WO PCT/US2000/041666 patent/WO2001034219A2/en active Application Filing
- 2000-10-27 ES ES00989735T patent/ES2303819T3/es not_active Expired - Lifetime
- 2000-10-27 EP EP08003235.2A patent/EP1949874B1/de not_active Expired - Lifetime
- 2000-10-27 CA CA002388542A patent/CA2388542A1/en not_active Abandoned
- 2000-10-27 DE DE60038742T patent/DE60038742T2/de not_active Expired - Lifetime
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0688545A1 (de) * | 1994-06-17 | 1995-12-27 | Terumo Kabushiki Kaisha | Dauerstent und Verfahren zu seiner Herstellung |
Also Published As
Publication number | Publication date |
---|---|
CA2388542A1 (en) | 2001-05-17 |
DE60038742D1 (de) | 2008-06-12 |
EP1949874A2 (de) | 2008-07-30 |
US6331186B1 (en) | 2001-12-18 |
ATE393606T1 (de) | 2008-05-15 |
EP1223892A2 (de) | 2002-07-24 |
DE60038742T2 (de) | 2009-05-20 |
ES2303819T3 (es) | 2008-09-01 |
EP1949874A3 (de) | 2011-03-16 |
JP2003513712A (ja) | 2003-04-15 |
WO2001034219A2 (en) | 2001-05-17 |
EP1223892B1 (de) | 2008-04-30 |
WO2001034219A3 (en) | 2002-02-21 |
JP4663945B2 (ja) | 2011-04-06 |
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