EP1910345A1 - Amides substitues, leur preparation et leur utilisation en tant que medicament - Google Patents

Amides substitues, leur preparation et leur utilisation en tant que medicament

Info

Publication number
EP1910345A1
EP1910345A1 EP06764178A EP06764178A EP1910345A1 EP 1910345 A1 EP1910345 A1 EP 1910345A1 EP 06764178 A EP06764178 A EP 06764178A EP 06764178 A EP06764178 A EP 06764178A EP 1910345 A1 EP1910345 A1 EP 1910345A1
Authority
EP
European Patent Office
Prior art keywords
group
alkyl
substituted
groups
atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06764178A
Other languages
German (de)
English (en)
Inventor
Kai Gerlach
Henning Priepke
Roland Pfau
Wolfgang Wienen
Annette Schuler-Metz
Georg Dahmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Boehringer Ingelheim International GmbH
Boehringer Ingelheim Pharma GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH, Boehringer Ingelheim Pharma GmbH and Co KG filed Critical Boehringer Ingelheim International GmbH
Priority to EP06764178A priority Critical patent/EP1910345A1/fr
Publication of EP1910345A1 publication Critical patent/EP1910345A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Abstract

Nouveaux amides substitués de formule générale (I) dans laquelle D, L, M, W et B sont tels que définis dans la description, leurs tautomères, leurs énantiomères, leurs diastéréomères, leurs mélanges et leurs sels, en particulier leurs sels acceptables sur le plan physiologique avec des acides ou des bases inorganiques ou organiques, qui possèdent des propriétés précieuses. Ces composés ont une action d'inhibition du facteur Xa.
EP06764178A 2005-07-19 2006-07-17 Amides substitues, leur preparation et leur utilisation en tant que medicament Withdrawn EP1910345A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06764178A EP1910345A1 (fr) 2005-07-19 2006-07-17 Amides substitues, leur preparation et leur utilisation en tant que medicament

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05015588 2005-07-19
EP06764178A EP1910345A1 (fr) 2005-07-19 2006-07-17 Amides substitues, leur preparation et leur utilisation en tant que medicament
PCT/EP2006/064302 WO2007009963A1 (fr) 2005-07-19 2006-07-17 Amides substitues, leur preparation et leur utilisation en tant que medicament

Publications (1)

Publication Number Publication Date
EP1910345A1 true EP1910345A1 (fr) 2008-04-16

Family

ID=35447449

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06764178A Withdrawn EP1910345A1 (fr) 2005-07-19 2006-07-17 Amides substitues, leur preparation et leur utilisation en tant que medicament

Country Status (7)

Country Link
US (1) US20070032473A1 (fr)
EP (1) EP1910345A1 (fr)
JP (1) JP2009501760A (fr)
AR (1) AR055201A1 (fr)
CA (1) CA2615447A1 (fr)
TW (1) TW200740798A (fr)
WO (1) WO2007009963A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20080145A1 (es) 2006-03-21 2008-02-11 Janssen Pharmaceutica Nv Tetrahidro-pirimidoazepinas como moduladores de trpv1
EP1975165A1 (fr) * 2007-03-27 2008-10-01 Boehringer Ingelheim Pharma GmbH & Co. KG Pyrrolidinamide substituée, sa fabrication et son utilisation en tant que médicament
WO2009063028A2 (fr) * 2007-11-15 2009-05-22 Boehringer Ingelheim International Gmbh Amides substitués, leur fabrication et utilisation sous forme de médicaments
WO2009063029A2 (fr) * 2007-11-16 2009-05-22 Boehringer Ingelheim International Gmbh Amides substitués, leur fabrication et utilisation en tant que médicaments
WO2009078999A1 (fr) 2007-12-17 2009-06-25 Janssen Pharmaceutica N.V. Modulateurs imidazolo-, oxazolo- et thiazolopyrimidines de trpv1
EP3078378B1 (fr) 2015-04-08 2020-06-24 Vaiomer Utilisation d'inhibiteurs du facteur xa destinés à réguler la glycémie

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19962924A1 (de) * 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
CA2511493A1 (fr) * 2002-12-25 2004-07-15 Daiichi Pharmaceutical Co., Ltd. Derives de diamine
US7199149B2 (en) * 2003-10-01 2007-04-03 Bristol Myers Squibb Company Monocyclic and bicyclic lactams as factor Xa inhibitors

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2007009963A1 *

Also Published As

Publication number Publication date
JP2009501760A (ja) 2009-01-22
WO2007009963A1 (fr) 2007-01-25
CA2615447A1 (fr) 2007-01-25
US20070032473A1 (en) 2007-02-08
AR055201A1 (es) 2007-08-08
TW200740798A (en) 2007-11-01

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20080219

AK Designated contracting states

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

17Q First examination report despatched

Effective date: 20090127

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20110131