EP1883435A1 - Administration device with forced priming - Google Patents
Administration device with forced primingInfo
- Publication number
- EP1883435A1 EP1883435A1 EP06721938A EP06721938A EP1883435A1 EP 1883435 A1 EP1883435 A1 EP 1883435A1 EP 06721938 A EP06721938 A EP 06721938A EP 06721938 A EP06721938 A EP 06721938A EP 1883435 A1 EP1883435 A1 EP 1883435A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- administration
- priming
- button
- product
- locking
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 230000037452 priming Effects 0.000 title claims abstract description 46
- 238000000034 method Methods 0.000 claims abstract description 22
- 239000003708 ampul Substances 0.000 claims abstract description 19
- 230000000903 blocking effect Effects 0.000 claims description 8
- 230000004308 accommodation Effects 0.000 abstract 1
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 4
- 230000004888 barrier function Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 102000004877 Insulin Human genes 0.000 description 2
- 108090001061 Insulin Proteins 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 229940125396 insulin Drugs 0.000 description 2
- 238000010276 construction Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3146—Priming, e.g. purging, reducing backlash or clearance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
Definitions
- the present invention relates to an administration device for administering a product after performing a priming process, wherein the device comprises a housing for receiving an ampoule with the product and a mechanism for propelling a plug in the ampoule, according to the claim an organism, especially a human, are injected.
- Various administration devices also known as injection pens, which are used to be able to administer patients, for example insulin or the like, are known in the prior art.
- injection pens which are used to be able to administer patients, for example insulin or the like
- it is necessary to perform a priming procedure prior to administration i.e. to remove air and possibly impurities from a cannula associated with the device by flushing with the product itself. It is not uncommon that the priming process is forgotten, which can occur especially in stressful situations, such as when a diabetic near a shock state in which he absolutely needs an insulin injection.
- an administering device which has the advantages that, on the one hand, the priming process does not occur before an administration procedure can be forgotten and on the other hand, the priming process can be performed as an inevitable process with low operating costs.
- the invention will be applied to single-use administration devices, but may also be used in multiple-use administration devices.
- the achievable according to the invention advantages are based on the fact that the mechanism for advancing the plug within the ampoule is associated with a locking arrangement which counteracts administration of the product without prior execution of the priming process, wherein the lock assembly is unlocked by performing the priming process and the mechanism for administering the product is released and operable.
- the device according to the invention has a priming button, via which the locking arrangement can be unlocked, wherein a locking member is brought by the operation of the priming button from a locking position to the release of the mechanism, preferably a delivery knob of the mechanism, for administering the product to effect.
- the administering device according to the invention comprises two operating buttons, one for the inevitable priming operation and the other for actuation only to effect administration of the product. This ease of handling ensures that a patient is able to perform the necessary operations, even in stressful situations.
- the locking arrangement comprises a switching member which obstructs the operation of an administration button in a blocking position, wherein the switching member is deflectable from a locking position, so that the administration button is actuated.
- the invention can be used in particular in a "disposable delivery device", since in such a case the barrier assembly as well as the delivery mechanism can be relatively easily carried out since they are only in one direction, ie, in the direction in which to cause a feed of the plug, must be designed.
- a switch member spring is provided for the switch member to deflect the switch member from the lock position, that is, the patient can actuate the priming button to cause the switch spring to act and deflect the switch member from a locked position.
- a simple operation is possible and the patient then only needs to worry about the operation of the administration button.
- the aforementioned blocking element can block the switching element in the blocking position.
- the locking arrangement preferably includes a priming rod which acts on the plug by actuation of the priming button. While the priming process is being performed, this also releases the mechanism for propelling the plug to administer the product.
- the mechanism preferably has an administration rod, which acts on the plug as a result of the actuation of an administration button.
- the administration rod is also associated with a preferably compressed spring which advances the delivery rod, which subsequently advances the plug within the ampule to effect administration of the product.
- the administration rod and the priming rod are arranged coaxially with each other or one inside the other, whereby the construction can be further simplified.
- the rods may also be arranged at an angle to each other, which would then complicate the overall mechanics of the barrier assembly and the delivery mechanism.
- Figure 1 is an axial longitudinal section through a preferred embodiment of a device according to the invention.
- FIG. 2 shows a 90 ° rotated axial longitudinal section through the embodiment according to FIG. 1.
- a device 10 for administering a product comprises a housing 12, into which an ampoule 14 with the product to be administered is inserted.
- a plug 16 is arranged, which is to move for administration of the product and for performing a priming process in the axial direction in the direction of a cannula 82 at the front end of the device 10.
- the ampoule 14 is connected or flanged via an ampoule system 18 to the administration mechanism.
- the ampoule can already be flanged to the manufacturer. Otherwise, this process is preferably performed by the patient, whenever a new, full ampoule 14 is to be inserted into the administering device 10.
- a cannula holder 80 is provided which holds the cannula 82.
- the cannula holder can be removed to the middle cannula and the cannula can thus be sterile to a canoe without direct contact and thus sterile.
- lense attachment 84 are attached to the ampoule 14 in order to perform an administration or a priming process.
- a priming button 30 is provided at the end of the cannula end of the device 10.
- the priming button 30 acts on a priming rod 20, which can reach up to the plug 16 in the ampoule.
- the priming button 30 acts on its operation on a locking member unlocking 32, which is also displaced axially in the direction of the cannula end of the device 10 upon actuation of the priming button 30.
- the locking member unlocking 32 is pushed forward by the operation of the priming button 30 and thereby performs locking arms 34 which are spread apart in the original state, together.
- the locking arms 34 are particularly apparent in Fig. 2 in their functional position.
- an administration button 26 is not operable and as soon as the switching member 26 has been torn from its blocking position, the locking legs 38, which are related to the administration button 36, are moved perpendicular to the axis of the device 10.
- locking fingers 42 are released, which have held an administration rod 22 in a primary position, in which position an administration spring 24 is held in a pretensioned position.
- the delivery rod is propelled forwardly toward the cannula portion of the device 10 and pushes the stopper 16 forward to perform an administration procedure.
- the mechanism for the administration is held within a guide block 40 in the housing 12, wherein the guide block is held within the possibly multi-part housing.
- the ampoule system 18 can also be held on the housing, so that the housing together with the guide block 40 and the ampoule system 18 forms a static skeleton within which the delivery mechanism and the locking arrangement 30, 32, 34, 36 are held and / or guided.
- the catching arms 34 can also be used directly to exert a blocking function with respect to the locking legs 38 and the locking fingers 42, respectively.
- the locking arms 34 need only be in engagement with a shoulder (not shown) on the locking legs 38 in its illustrated locked state and by the operation of the priming button 30 and the advancement of the locking member unlocking 32 would have the locking arms 34 out of engagement with the shoulders or abutment (not shown) arrive at the locking legs.
- a blocking function could be exercised without the switching element 26, which is canceled by performing a priming process.
Abstract
The invention relates to an administration device for administration of a product after carrying out a priming process, whereby a housing (12), for accommodation of an ampoule (14) with the product and a mechanism (22, 24, 26) for propelling a plug (16) in the ampoule, is provided. According to the invention, a lock arrangement (32, 34, 36, 38) is provided for the mechanism which prevents an administration of the product without a previous execution of the priming process, whereby, on carrying out the priming process, the lock arrangement (32, 34, 36, 38) is released and the mechanism (22, 24, 26) activated and operable for administration of the product.
Description
Verabreichungsvorrichtung mit Zwangs-Priming Delivery device with forced priming
Die vorliegende Erfindung betrifft eine Verabreichungsvorrichtung zur Verabrechung eines Produktes nach Durchführung eines Priming-Vorganges, wobei die Vorrichtung ein Gehäuse zur Aufnahme einer Ampulle mit dem Produkt und einer Mechanik zum Vortrieb eines Stopfens in der Ampulle aufweist, gemäß dem Patentanspruch 1. Das Produkt soll in einen Organismus, insbesondere einen Menschen, injiziert werden.The present invention relates to an administration device for administering a product after performing a priming process, wherein the device comprises a housing for receiving an ampoule with the product and a mechanism for propelling a plug in the ampoule, according to the claim an organism, especially a human, are injected.
Im Stand der Technik sind diverse Verabreichungsvorrichtungen, auch Injektionspen genannt, bekannt, die verwendet werden, um Patienten beispielsweise Insulin oder dgl. verabreichen zu können. Bei derartigen Verabreichungsvorrichtungen ist es nötig, vor einer Verabreichung einen Priming-Vorgang auszuführen, d.h., aus einer zur Vorrichtung gehörigen Kanüle Luft und eventuell Verunreinigungen durch ein Spülen mit dem Produkt selbst zu entfernen. Es kommt nicht selten vor, dass der Priming-Vorgang vergessen wird, was insbesondere auch in Stresssituationen auftreten kann, etwa wenn ein Diabetiker einem Schockzustand nahe ist, in dem er unbedingt eine Insulininjektion benötigt.Various administration devices, also known as injection pens, which are used to be able to administer patients, for example insulin or the like, are known in the prior art. In such delivery devices, it is necessary to perform a priming procedure prior to administration, i.e. to remove air and possibly impurities from a cannula associated with the device by flushing with the product itself. It is not uncommon that the priming process is forgotten, which can occur especially in stressful situations, such as when a diabetic near a shock state in which he absolutely needs an insulin injection.
Es ist folglich eine Aufgabe gemäß der vorliegenden Erfindung, eine Verabreichungsvorrichtung vorzuschlagen, bei der es kaum möglich ist, den Priming-Vorgang auszulassen.It is therefore an object of the present invention to propose an administering device in which it is hardly possible to omit the priming process.
Diese Aufgabe wird durch eine Verabreichungsvorrichtung gemäß dem Patentanspruch 1 gelöst. Zweckmäßige Ausführμngsformen der erfindungsgemäßen Verabreichungsvorrichtung werden durch die Unteransprüche definiert.This object is achieved by an administration device according to claim 1. Expedient embodiments of the administration device according to the invention are defined by the subclaims.
Gemäß der Erfindung wird eine Verabreichungsvorrichtung vorgeschlagen, die die Vorteile aufweist, dass einerseits der Priming-Vorgang vor einem Verabreichungsvorgang nicht
vergessen werden kann und andererseits kann der Priming- Vorgang als zwangsläufiger Vorgang mit geringem Betätigungsaufwand durchgeführt werden.According to the invention, an administering device is proposed, which has the advantages that, on the one hand, the priming process does not occur before an administration procedure can be forgotten and on the other hand, the priming process can be performed as an inevitable process with low operating costs.
Bevorzugt wird die Erfindung bei Einmal-Verabreichungsvorrichtungen zur Anwendung gelangen, kann aber auch bei vielfach verwendbaren Verabreichungsvorrichtungen zur Anwendung kommen.Preferably, the invention will be applied to single-use administration devices, but may also be used in multiple-use administration devices.
Die gemäß der Erfindung erzielbaren Vorteile beruhen darauf, dass der Mechanik zum Vortrieb des Stopfens innerhalb der Ampulle eine Sperranordnung zugeordnet ist, die einer Verabreichung des Produktes ohne vorherige Durchführung des Priming- Vorganges entgegenwirkt, wobei durch die Durchführung des Priming- Vorganges die Sperranordnung entriegelt wird und die Mechanik zur Verabreichung des Produktes freigegeben und betätigbar wird.The achievable according to the invention advantages are based on the fact that the mechanism for advancing the plug within the ampoule is associated with a locking arrangement which counteracts administration of the product without prior execution of the priming process, wherein the lock assembly is unlocked by performing the priming process and the mechanism for administering the product is released and operable.
Bevorzugt weist die erfindungsgemäße Vorrichtung einen Priming-Knopf auf, über den die Sperranordnung entriegelbar ist, wobei ein Sperrorgan durch die Betätigung des Priming- Knopfes aus einer Sperrposition gebracht wird, um die Freigabe der Mechanik, bevorzugt eines Verabreichungsknopfes der Mechanik, zur Verabreichung des Produktes zu bewirken. D.h., die erfindungsgemäße Verabreichungsvorrichtung umfasst in einer bevorzugten Ausführungsform zwei Betätigungsknöpfe, einmal für den unausweichlich auszuführenden pri- ming-Vorgang und einen zweiten, der nur anschließend zu betätigen ist, um die Verabreichung des Produktes zu bewirken. Diese einfache Handhabbarkeit garantiert, dass ein Patient auch in Stresssituationen dazu in der Lage ist, die erforderlichen Vorgänge vorzunehmen.Preferably, the device according to the invention has a priming button, via which the locking arrangement can be unlocked, wherein a locking member is brought by the operation of the priming button from a locking position to the release of the mechanism, preferably a delivery knob of the mechanism, for administering the product to effect. That is, in a preferred embodiment, the administering device according to the invention comprises two operating buttons, one for the inevitable priming operation and the other for actuation only to effect administration of the product. This ease of handling ensures that a patient is able to perform the necessary operations, even in stressful situations.
Gemäß einer weiteren bevorzugten Ausführungsform umfasst die Sperranordnung ein Schaltglied, das in einer Sperrposition die Betätigung eines Verabreichungsknopfes behindert, wobei das Schaltglied aus einer Sperrposition auslenkbar ist, so dass der Verabreichungsknopf betätigbar ist. Auch bei dieser Variante ist es möglich, in Stresssituationen sowohl eine einfache Handhabbarkeit als auch die dringend erforderliche Reihenfolge der vorzunehmenden Vorgänge sicherzustellen.
Festzuhalten ist, dass die Erfindung insbesondere bei einer "Wegwerf- Verabreichungsvorrichtung zum Einsatz gelangen kann, da in einem solchen Falle die Sperranordnung wie auch die Verabreichungsmechanik relativ einfach ausgeführt werden können, da sie nur in einer Richtung, d.h., in der Richtung, in der ein Vorschub des Stopfens zu bewirken ist, ausgelegt sein muss.According to a further preferred embodiment, the locking arrangement comprises a switching member which obstructs the operation of an administration button in a blocking position, wherein the switching member is deflectable from a locking position, so that the administration button is actuated. Also in this variant, it is possible to ensure both easy handling and the urgently required sequence of operations to be carried out in stress situations. It should be noted that the invention can be used in particular in a "disposable delivery device", since in such a case the barrier assembly as well as the delivery mechanism can be relatively easily carried out since they are only in one direction, ie, in the direction in which to cause a feed of the plug, must be designed.
Bevorzugt dient für das Schaltglied eine Schaltgliedfeder, um das Schaltglied aus der Sperrposition auszulenken, d.h., der Patient kann durch Betätigung des Priming-Knopfes dafür sorgen, dass die Schaltgliedfeder in Aktion tritt und das Schaltglied aus einer Sperrposition auslenkt. Auch hier ist eine einfache Betätigung möglich und der Patient braucht sich anschließend nur noch um die Betätigung des Verabreichungsknopfes zu kümmern.Preferably, a switch member spring is provided for the switch member to deflect the switch member from the lock position, that is, the patient can actuate the priming button to cause the switch spring to act and deflect the switch member from a locked position. Again, a simple operation is possible and the patient then only needs to worry about the operation of the administration button.
Gemäß einer weiteren bevorzugten Ausfiihrungsform kann das zuvor genannte Sperrorgan das Schaltglied in der Sperrposition sperren.According to a further preferred embodiment, the aforementioned blocking element can block the switching element in the blocking position.
Die Sperranordnung enthält bevorzugt eine Priming-Stange, die durch Betätigung des Priming-Knopfes auf den Stopfen einwirkt. Während dabei der Priming- Vorgang durchgeführt wird, wird hierdurch die Mechanik zum Vortrieb des Stopfens zur Verabreichung des Produktes ebenfalls freigegeben. Dabei weist bevorzugt die Mechanik eine Verabreichungsstange auf, die in Folge der Betätigung eines Verabreichungsknopfes auf den Stopfen einwirkt.The locking arrangement preferably includes a priming rod which acts on the plug by actuation of the priming button. While the priming process is being performed, this also releases the mechanism for propelling the plug to administer the product. In this case, the mechanism preferably has an administration rod, which acts on the plug as a result of the actuation of an administration button.
Bevorzugt ist dabei auch der Verabreichungsstange eine bevorzugt komprimierte Feder zugeordnet, die die Verabreichungsstange vorantreibt, die nachfolgend den Stopfen innerhalb der Ampulle vorantreibt, um eine Verabreichung des Produktes durchzuführen.Preferably, the administration rod is also associated with a preferably compressed spring which advances the delivery rod, which subsequently advances the plug within the ampule to effect administration of the product.
Bevorzugt sind die Verabreichungsstange und die Priming-Stange koaxial zueinander oder ineinander angeordnet, wodurch der Aufbau noch weiter vereinfacht werden kann. Natürlich können die Stangen auch jeweils in einem Winkel zueinander angeordnet sein, was dann jedoch die Gesamtmechanik der Sperranordnung und der Verabreichungsmechanik verkomplizieren würde.
Nachfolgend wird eine bevorzugte Ausführungsform gemäß der Erfindung unter Bezugnahme auf die beigefügten Figuren näher erläutert. Dabei werden weitere Merkmale, Zielsetzungen und Vorteile gemäß der Erfindung offenbart. In den Darstellungen sind gleiche oder wenigstens funktionsgleiche Bestandteile durch die gleichen Bezugsziffern benannt, so dass eine mehrfache Beschreibung der gleichen Teile wegbleiben kann.Preferably, the administration rod and the priming rod are arranged coaxially with each other or one inside the other, whereby the construction can be further simplified. Of course, the rods may also be arranged at an angle to each other, which would then complicate the overall mechanics of the barrier assembly and the delivery mechanism. Hereinafter, a preferred embodiment according to the invention will be explained in more detail with reference to the accompanying figures. In this case, further features, objectives and advantages are disclosed according to the invention. In the illustrations, identical or at least functionally identical components are designated by the same reference numerals, so that a multiple description of the same parts can be omitted.
In den Darstellungen zeigen:In the illustrations show:
Fig. 1 einen axialen Längsschnitt durch eine bevorzugte Ausführungsform einer Vorrichtung gemäß der Erfindung; undFigure 1 is an axial longitudinal section through a preferred embodiment of a device according to the invention. and
Fig. 2 einen um 90 ° gedrehten axialen Längsschnitt durch die Ausfuhrungsform gemäß Fig. 1.2 shows a 90 ° rotated axial longitudinal section through the embodiment according to FIG. 1.
Eine Vorrichtung 10 zur Verabreichung eines Produktes umfasst ein Gehäuse 12, in das eine Ampulle 14 mit dem zu verabreichenden Produkt eingesetzt ist. In der Ampulle 14 ist ein Stopfen 16 angeordnet, der zur Verabreichung des Produktes und zur Durchführung eines Priming- Vorganges in Axialrichtung in Richtung einer Kanüle 82 am vorderen Ende der Vorrichtung 10 zu verschieben ist.A device 10 for administering a product comprises a housing 12, into which an ampoule 14 with the product to be administered is inserted. In the ampoule 14, a plug 16 is arranged, which is to move for administration of the product and for performing a priming process in the axial direction in the direction of a cannula 82 at the front end of the device 10.
Die Ampulle 14 ist über eine Ampullenanlage 18 an die Verabreichungsmechanik angeschlossen oder angeflanscht.The ampoule 14 is connected or flanged via an ampoule system 18 to the administration mechanism.
In dem Falle, dass es sich bei der erfindungsgemäßen Vorrichtung um eine einmalig zu verwendende Vorrichtung handelt, kann die Ampulle bereits beim Hersteller angeflanscht werden. Ansonsten ist dieser Vorgang bevorzugt vom Patienten durchzufuhren, und zwar immer dann, wenn eine neue, volle Ampulle 14 in die Verabreichungsvorrichtung 10 einzusetzen ist.In the event that the device according to the invention is a device which can be used once, the ampoule can already be flanged to the manufacturer. Otherwise, this process is preferably performed by the patient, whenever a new, full ampoule 14 is to be inserted into the administering device 10.
Am vorderen Ende der Vorrichtung 10 ist eine Kanülenhalterung 80 vorgesehen, die die Kanüle 82 hält. Die Kanülenhalterung kann zur Mittelkanüle abgenommen werden und die Kanüle kann auf diese Weise ohne unmittelbare Berührung und damit steril an einen Kanu-
lenansatz 84 an der Ampulle 14 angesetzt werden, um eine Verabreichung bzw. einen Pri- ming-Vorgang durchzuführen.At the front end of the device 10, a cannula holder 80 is provided which holds the cannula 82. The cannula holder can be removed to the middle cannula and the cannula can thus be sterile to a canoe without direct contact and thus sterile. lense attachment 84 are attached to the ampoule 14 in order to perform an administration or a priming process.
An dem Kanülenende entgegen gesetzten Ende der Vorrichtung 10 ist ein Priming-Knopf 30 vorgesehen. Der Priming-Knopf 30 wirkt auf eine Priming-Stange 20 ein, die bis zu dem Stopfen 16 in der Ampulle reichen kann. Der Priming-Knopf 30 wirkt bei seiner Betätigung auch auf eine Sperrgliedentriegelung 32 ein, die bei Betätigung des Priming-Knopfes 30 ebenfalls axial in Richtung des Kanülenendes der Vorrichtung 10 verschoben wird. Damit wird durch die Betätigung des Priming-Knopfes 30 die Sperrgliedentriegelung 32 nach vorne geschoben und führt dabei Sperrarme 34, die im Urzustand aufgespreizt sind, zusammen. Die Sperrarme 34 sind in ihrer Funktionsstellung besonders aus Fig. 2 ersichtlich. Damit wird durch die Betätigung des Priming-Knopfes 30 nicht nur die Priming-Stange 20 nach vorne bewegt, sondern es werden auch die Sperrarme 34 radial nach innen ausgelenkt, wodurch die auf einem Schaltglied 36 abgestützten Sperrarme 34 außer Eingriff zu dem Schaltglied 36 gelangen. Das Schaltglied 36 wird hierdurch frei und eine Schaltgliedfeder 28 zieht das Schaltglied in Richtung des Priming-Knopfes 30, was anhand von Fig. 2 leicht nachvollzogen werden kann.At the end of the cannula end of the device 10, a priming button 30 is provided. The priming button 30 acts on a priming rod 20, which can reach up to the plug 16 in the ampoule. The priming button 30 acts on its operation on a locking member unlocking 32, which is also displaced axially in the direction of the cannula end of the device 10 upon actuation of the priming button 30. Thus, the locking member unlocking 32 is pushed forward by the operation of the priming button 30 and thereby performs locking arms 34 which are spread apart in the original state, together. The locking arms 34 are particularly apparent in Fig. 2 in their functional position. Thus, not only the priming rod 20 is moved forward by the operation of the priming knob 30, but it also the locking arms 34 are deflected radially inwardly, whereby the supported on a switching member 36 locking arms 34 disengage from the switching member 36. The switching member 36 is thereby released and a switching member spring 28 pulls the switching member in the direction of the priming button 30, which can be easily understood with reference to FIG.
Solange das Schaltglied 36 in seiner Ursteilung ist, ist ein Verabreichungsknopf 26 nicht betätigbar und sobald das Schaltglied 26 aus seiner Sperrstellung gerissen worden ist, können die Sperrschenkel 38, die auf den Verabreichungsknopf 36 bezogen sind, senkrecht zur Achse der Vorrichtung 10 bewegt werden. Hierdurch werden Sperrfinger 42 freigegeben, die eine Verabreichungsstange 22 in einer Urposition gehalten haben, wobei in dieser Ur- position eine Verabreichungsfeder 24 in einer vorgespannten Stellung gehalten wird. Sobald die Sperrfinger 42 nicht mehr im Hintergriff mit einer Schulter 44 der Verabreichungsstange 22 sind, wird folglich die Verabreichungsstange nach vorne in Richtung des Kanülenbereichs der Vorrichtung 10 vorangetrieben und stößt den Stopfen 16 nach vorne, um einen Verabreichungsvorgang durchzuführen.As long as the switching member 36 is in its original division, an administration button 26 is not operable and as soon as the switching member 26 has been torn from its blocking position, the locking legs 38, which are related to the administration button 36, are moved perpendicular to the axis of the device 10. As a result, locking fingers 42 are released, which have held an administration rod 22 in a primary position, in which position an administration spring 24 is held in a pretensioned position. Thus, once the locking fingers 42 are no longer in the rearward engagement with a shoulder 44 of the delivery rod 22, the delivery rod is propelled forwardly toward the cannula portion of the device 10 and pushes the stopper 16 forward to perform an administration procedure.
Die Mechanik für die Verabreichung ist innerhalb eines Führungsblockes 40 im Gehäuse 12 gehalten, wobei der Führungsblock innerhalb des eventuell auch mehrteiligen Gehäuses gehalten wird. Am Gehäuse kann die Ampullenanlage 18 ebenfalls gehalten sein, so dass
das Gehäuse zusammen mit dem Führungsblock 40 und der Ampullenanlage 18 ein statisches Grundgerüst bildet, innerhalb dessen die Verabreichungsmechanik und die Sperranordnung 30, 32, 34, 36 gehalten und/oder geführt werden.The mechanism for the administration is held within a guide block 40 in the housing 12, wherein the guide block is held within the possibly multi-part housing. The ampoule system 18 can also be held on the housing, so that the housing together with the guide block 40 and the ampoule system 18 forms a static skeleton within which the delivery mechanism and the locking arrangement 30, 32, 34, 36 are held and / or guided.
Im Hinblick auf die dargestellte Ausführungsform ist festzuhalten, dass natürlich die Fangarme 34 auch unmittelbar dazu eingesetzt werden können, eine Sperrfunktion in Bezug auf die Sperrschenkel 38 bzw. die Sperrfinger 42 auszuüben. Zu diesem Zweck brauchten die Sperrarme 34 lediglich in Eingriff mit einer Schulter (nicht dargestellt) an den Sperrschenkeln 38 in ihrem dargestellten Sperrzustand sein und durch die Betätigung des Priming- Knopfes 30 und den Vorschub der Sperrgliedentriegelung 32 müssten die Sperrarme 34 außer Eingriff mit den Schultern oder Widerlagern (nicht dargestellt) an den Sperrschenkeln gelangen. Hier könnte dann ohne das Schaltglied 26 ebenfalls eine Sperrfunktion ausgeübt werden, die durch Ausführung eines Priming- Vorganges aufgehoben wird.With regard to the illustrated embodiment, it should be noted that, of course, the catching arms 34 can also be used directly to exert a blocking function with respect to the locking legs 38 and the locking fingers 42, respectively. For this purpose, the locking arms 34 need only be in engagement with a shoulder (not shown) on the locking legs 38 in its illustrated locked state and by the operation of the priming button 30 and the advancement of the locking member unlocking 32 would have the locking arms 34 out of engagement with the shoulders or abutment (not shown) arrive at the locking legs. Here then a blocking function could be exercised without the switching element 26, which is canceled by performing a priming process.
Entsprechendes wäre auch möglich, wenn lediglich das Schaltglied 36 vorgesehen wäre, wobei durch die Betätigung des Priming-Knopfes 30 über eine Umlenkung ohne Verwendung der Sperrarme 34 das Schaltglied aus seiner dargestellten Ursprungsposition entfernt werden könnte, um den Verabreichungsknopf 26 freizugeben.
The same would also be possible if only the switching member 36 were provided, whereby the switching member could be removed from its illustrated original position by the operation of the priming knob 30 via a deflection without using the locking arms 34 to release the administration button 26.
B ezugszeichenlisteReference list
Gehäuse 12Housing 12
Ampulle 14Ampoule 14
Stopfen 16Plug 16
Ampullenanlage 18Ampoule system 18
Primingstange 20Priming rod 20
Verabreichungsstange 22Delivery bar 22
Verabreichungsfeder 24Administration spring 24
Verabreichungskopf 26Administration head 26
Schaltgleichfeder 28Switching balanced spring 28
Priming-Knopf 30Priming button 30
Sperrgliedentriegelung 32Locking member unlocking 32
Sperr arme 34Barrier arms 34
Schaltglied 36Switching element 36
Verbindungsschenkel 37Connecting leg 37
Sperrschenkel 38Locking leg 38
Führungsblock 40Guide block 40
Sperrfinger 42Locking finger 42
Schulter 44Shoulder 44
Kanülenhalterung 80Needle holder 80
Kanüle 82Cannula 82
Kanülenansatz 84
Cannula attachment 84
Claims
1. Verabreichungsvorrichtung zur Verabreichung eines Produktes nach Durchführung eines Priming- Vorganges mit folgenden Merkmalen: einem Gehäuse (12) zur Aufnahme einer Ampulle (14) mit dem Produkt und einer Mechanik (22, 24, 26) zum Vortrieb eines Stopfens (16), wobei der Mechanik eine Sperranordnung (32, 34, 36, 38) zugeordnet ist, die einer Verabreichung des Produktes ohne vorherige Durchführung des Priming- Vorganges entgegenwirkt, wobei durch die Durchführung des Priming- Vorganges die Sperranordnung (32, 34, 36, 38) entriegelt wird und die Mechanik (22, 24, 26) zur Verabreichung des Produktes freigegeben und betätigbar wird.A delivery device for administering a product after a priming operation has the following features: a housing (12) for receiving an ampoule (14) with the product and a mechanism (22, 24, 26) for advancing a plug (16), wherein the mechanism is associated with a locking arrangement (32, 34, 36, 38) which counteracts administration of the product without prior execution of the priming procedure, wherein by performing the priming procedure the locking arrangement (32, 34, 36, 38) is unlocked and the mechanism (22, 24, 26) is released and operable to administer the product.
2. Verabreichungsvorrichtung nach Anspruch 1, wobei die Sperranordnung über einen Priming-Knopf (30) entriegelbar ist, wobei ein Sperrorgan (34) durch die Betätigung des Priming-Knopfes (30) aus seiner Sperrposition gebracht wird, um die Freigabe der Mechanik (22, 24, 26) bevorzugt eines Verabreichungsknopfes (26), zur Verabreichung des Produktes zu bewirken.2. The delivery device according to claim 1, wherein the locking arrangement is unlockable via a priming button (30), wherein a locking member (34) by the operation of the priming button (30) is brought from its locked position to the release of the mechanism (22 , 24, 26), preferably an administration button (26), for administering the product.
3. Verabreichungsvorrichtung nach einem der Ansprüche 1 oder 2, dadurch gekennzeichnet, dass die Sperranordnung (32, 34, 36, 38) ein Schaltglied (36) umfasst, dass in einer Sperrposition der Betätigung eines Verabreichungsknopfes (26) behindert, wobei das Schaltglied (26) aus einer Sperrposition auslenkbar ist, so dass der Verabreichungsknopf (26) betätigbar ist.3. Administration device according to one of claims 1 or 2, characterized in that the locking arrangement (32, 34, 36, 38) comprises a switching member (36) that obstructs the operation of an administration button (26) in a blocking position, wherein the switching element ( 26) is deflectable from a locking position, so that the administration button (26) is actuated.
4. Verabreichungsvorrichtung nach Anspruch 3, wobei das Schaltglied (36) durch eine Schaltgliedfeder (28) aus der Sperrposition ausgelenkt wird.4. Administration device according to claim 3, wherein the switching member (36) by a switching member spring (28) is deflected from the locking position.
5. Verabreichungsvorrichtung nach Anspruch 2 mit 3, wobei das Sperrorgan (34) das Schaltglied in der Sperrposition sperrt. 5. Administration device according to claim 2 with 3, wherein the blocking member (34) blocks the switching member in the locked position.
6. Verabreichungsvorrichtung nach einem der Ansprüche 2 bis 5, dadurch gekennzeichnet, dass die Sperranordnung eine Priming-Stange (22) umfasst, die durch Betätigung des Priming-Knopfes (30) auf den Stopfen einwirkt, um den Priming- Vorgang durchzufuhren, wobei die Mechanik zum Vortrieb des Stopfens (16) zur Verabreichung des Stopfens freigegeben wird.6. administering device according to any one of claims 2 to 5, characterized in that the locking arrangement comprises a priming rod (22) which acts by pressing the priming button (30) on the plug to perform the priming process, wherein the Mechanism for advancing the plug (16) is released for the administration of the plug.
7. Verabreichungsvorrichtung nach einem der Ansprüche 1 bis 6, wobei die Mechanik (22, 24, 26) eine Verabreichungsstange (22) umfasst, die in Folge der Betätigung des Verabreichungsknopfes (26) auf den Stopfen (16) einwirkt.A delivery device according to any one of claims 1 to 6, wherein the mechanism (22, 24, 26) comprises an administration rod (22) which acts on the plug (16) as a result of the actuation of the administration button (26).
8. Verabreichungsvorrichtung nach Anspruch 7, wobei an der Verabreichungsstange (22) eine Verabreichungsfeder (24) angreift, die erstere vorantreibt, um eine Verabreichung durchzufahren.The delivery device of claim 7, wherein an administration spring (24) acts on the delivery rod (22) to propel the former to perform administration.
9. Verabreichungsvorrichtung nach Anspruch 8, wobei die Priming-Stange (20) und die Verabreichungsstange (22) koaxial zueinander oder ineinander angeordnet sind. A delivery device according to claim 8, wherein the priming rod (20) and the delivery rod (22) are coaxial with each other or with each other.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005022532A DE102005022532A1 (en) | 2005-05-17 | 2005-05-17 | Delivery device with forced priming |
PCT/CH2006/000236 WO2006122437A1 (en) | 2005-05-17 | 2006-04-28 | Administration device with forced priming |
Publications (1)
Publication Number | Publication Date |
---|---|
EP1883435A1 true EP1883435A1 (en) | 2008-02-06 |
Family
ID=36603643
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP06721938A Withdrawn EP1883435A1 (en) | 2005-05-17 | 2006-04-28 | Administration device with forced priming |
Country Status (7)
Country | Link |
---|---|
US (1) | US20080208123A1 (en) |
EP (1) | EP1883435A1 (en) |
JP (1) | JP2008539909A (en) |
CN (1) | CN101175518A (en) |
AU (1) | AU2006246891B2 (en) |
DE (1) | DE102005022532A1 (en) |
WO (1) | WO2006122437A1 (en) |
Families Citing this family (24)
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GB2433032A (en) * | 2005-12-08 | 2007-06-13 | Owen Mumford Ltd | Syringe with dose adjustment means |
US9950116B2 (en) * | 2009-06-01 | 2018-04-24 | Sanofi-Aventis Deutschland Gmbh | Dose setting mechanism for priming a drug delivery device |
US9238106B2 (en) | 2009-06-01 | 2016-01-19 | Sanofi-Aventis Deutschland Gmbh | Dose setting mechanism for priming a drug delivery device |
US9345840B2 (en) * | 2009-06-01 | 2016-05-24 | Sanofi-Aventis Deutschland Gmbh | Drug delivery dose setting mechanism with variable maximum dose |
US8728043B2 (en) * | 2009-06-01 | 2014-05-20 | Sanofi-Aventis Deutschland Gmbh | Drive mechanism for a drug delivery device |
US9623187B2 (en) * | 2009-06-01 | 2017-04-18 | Sanofi-Aventis Deutschland Gmbh | Resettable drug delivery device |
US9457150B2 (en) * | 2009-06-01 | 2016-10-04 | Sanofi-Aventis Deutschland Gmbh | Biasing mechanism for a drug delivery device |
US9108007B2 (en) * | 2009-06-01 | 2015-08-18 | Sanofi-Aventis Deutschland Gmbh | Spindle and bearing combination and drug delivery device |
US20110015576A1 (en) * | 2009-06-01 | 2011-01-20 | Sanofi-Aventis Deutschland Gmbh | Medicament identification system for multi-dose injection devices |
US10034982B2 (en) | 2009-06-01 | 2018-07-31 | Sanofi-Aventis Deutschland Gmbh | Spindle for a drug delivery device |
US9199040B2 (en) | 2009-06-01 | 2015-12-01 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device last dose lock-out mechanism |
US8974423B2 (en) * | 2009-06-01 | 2015-03-10 | Sanofi-Aventis Deutschland Gmbh | Resettable drug delivery device |
US8672896B2 (en) | 2009-06-01 | 2014-03-18 | Sanofi-Aventis Deutschland Gmbh | Inner housing for a drug delivery device |
US9125994B2 (en) * | 2009-06-01 | 2015-09-08 | Sanofi—Aventis Deutschland GmbH | Drug delivery device with dose dial sleeve rotational stop |
US8585656B2 (en) | 2009-06-01 | 2013-11-19 | Sanofi-Aventis Deutschland Gmbh | Dose setting mechanism for priming a drug delivery device |
US9463283B2 (en) * | 2009-06-01 | 2016-10-11 | Sanofi-Aventis Deutschland Gmbh | Dosing mechanism for a drug deliver device |
US8257319B2 (en) | 2009-06-01 | 2012-09-04 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device inner housing having helical spline |
CN106139325B (en) * | 2015-04-01 | 2020-06-26 | 群康生技股份有限公司 | Injection pen |
CN106139322A (en) * | 2015-04-01 | 2016-11-23 | 群康生技股份有限公司 | The locked configuration of injection pen |
US11065387B2 (en) | 2015-11-13 | 2021-07-20 | Shl Medical Ag | Activation mechanism for a medicament delivery device and a medicament delivery device using the activation mechanism |
EP3723828B1 (en) | 2017-12-13 | 2023-09-13 | Regeneron Pharmaceuticals, Inc. | Devices and methods for precision dose delivery |
EP3870119A4 (en) * | 2018-10-26 | 2022-07-20 | Singapore Health Services Pte. Ltd. | Device and method for ophthalmic extraction and injection |
KR20210154210A (en) * | 2019-04-18 | 2021-12-20 | 베링거 인겔하임 인터내셔날 게엠베하 | dosing device for administration of a fluid |
MA54325A (en) | 2019-06-05 | 2022-05-11 | Regeneron Pharma | DEVICES AND METHODS FOR ACCURATE DOSE DELIVERY |
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US527287A (en) * | 1894-10-09 | Mattress | ||
US4894054A (en) * | 1988-06-20 | 1990-01-16 | Miskinyar Shir A | Preloaded automatic disposable syringe |
DE4112259A1 (en) * | 1991-04-15 | 1992-10-22 | Medico Dev Investment Co | INJECTION DEVICE |
EP0518416A1 (en) * | 1991-06-13 | 1992-12-16 | Duphar International Research B.V | Injection device |
FR2815543B1 (en) * | 2000-10-19 | 2003-10-24 | Sedat | SELF-INJECTION SYRINGE OF AN EXTEMPORANEOUS MIXTURE |
DE10342058B4 (en) * | 2003-09-11 | 2007-10-25 | Tecpharma Licensing Ag | Administration device for an injectable product with a trigger safety device |
-
2005
- 2005-05-17 DE DE102005022532A patent/DE102005022532A1/en not_active Withdrawn
-
2006
- 2006-04-28 AU AU2006246891A patent/AU2006246891B2/en not_active Ceased
- 2006-04-28 CN CNA2006800165224A patent/CN101175518A/en active Pending
- 2006-04-28 WO PCT/CH2006/000236 patent/WO2006122437A1/en not_active Application Discontinuation
- 2006-04-28 JP JP2008510380A patent/JP2008539909A/en active Pending
- 2006-04-28 EP EP06721938A patent/EP1883435A1/en not_active Withdrawn
-
2007
- 2007-11-16 US US11/941,511 patent/US20080208123A1/en not_active Abandoned
Non-Patent Citations (1)
Title |
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See references of WO2006122437A1 * |
Also Published As
Publication number | Publication date |
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CN101175518A (en) | 2008-05-07 |
AU2006246891A1 (en) | 2006-11-23 |
WO2006122437A1 (en) | 2006-11-23 |
US20080208123A1 (en) | 2008-08-28 |
JP2008539909A (en) | 2008-11-20 |
DE102005022532A1 (en) | 2006-11-23 |
AU2006246891B2 (en) | 2010-03-04 |
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