EP1833457A1 - Hautpflegezusammensetzungen - Google Patents
HautpflegezusammensetzungenInfo
- Publication number
- EP1833457A1 EP1833457A1 EP05818617A EP05818617A EP1833457A1 EP 1833457 A1 EP1833457 A1 EP 1833457A1 EP 05818617 A EP05818617 A EP 05818617A EP 05818617 A EP05818617 A EP 05818617A EP 1833457 A1 EP1833457 A1 EP 1833457A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- composition
- starch
- skin
- ammonium salt
- starch derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/54—Polymers characterized by specific structures/properties
- A61K2800/542—Polymers characterized by specific structures/properties characterized by the charge
- A61K2800/5426—Polymers characterized by specific structures/properties characterized by the charge cationic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/594—Mixtures of polymers
Definitions
- compositions for use in skincare in particular to compositions intended to have a moisturising effect when applied topically to the skin.
- compositions are commonly applied directly to the skin. These include compositions intended to have a therapeutic effect upon the skin, as well as cosmetic compositions that are intended to modify the appearance of the skin.
- compositions suited to the type and/or age of the skin are applied to the skin with the aim of maintaining the skin in a smooth and supple condition.
- Dry skin is characterised by a lack of moisture caused on the one hand by increased water loss and on the other hand by reduced water-holding capacity. These effects may come about as a result of exposure of the skin to, for instance, conditions of low humidity, to wind, or such effects may be due to genetic predisposition.
- the balance of water loss and water-holding capacity may also be disturbed by prolonged exposure to surfactants, which promote dissolution of lipids in the skin that otherwise help to retain moisture in the stratum corneum act as a water loss shield.
- moisturisation ie the maintenance or elevation of the level of hydration of the skin. Improved moisturisation may prevent or inhibit the occurrence of dry and flaky skin, and may improve the elasticity and smoothness of the skin.
- Many products are used solely for their moisturising properties, eg as "Day Creams” that are intended to be applied and worn throughout the day. Similarly, “Night Creams” are applied before the user retires for the night and are worn throughout the hours of sleep.
- a disadvantage of known compositions that are intended to have a moisturising effect on the skin is that the effect may be less than would otherwise be desired, and more particularly may be less long-lasting than would be desired.
- the composition to the skin may initially give rise to a benefit, that benefit may not be as great as would be desired, may not persist for as long as would be desired, and/or may not be as constant as would be desired.
- moisturisation increases over the course of about two hours, but then falls. Where the moisturisation effect is longer lasting, the degree of moisturisation may vary considerably with time, whereas a more uniform, more substantially constant effect would be preferable.
- compositions of this type should not have to be frequently reapplied in order for the benefit to be maintained.
- a skincare composition that exerts a moisturising effect that persists for prolonged periods, and in particular for compositions that exert a moisturising effect on the skin that lasts sufficiently long for the effect to be maintained by application of the composition no more frequently than four times per day, and ideally only once or twice per day.
- a material known as "Advanced Moisture Complex” is available from Engelhard Corporation and comprises a complex of six different moisturising agents, viz glycerin, sodium PCA, urea, trehalose, Polyquaterniurn-51 and sodium hyaluronate.
- each of these components is a performance ingredient in its own right, yet none of them alone provide sustained long-term moisturisation.
- the same document discloses a cream formulation comprising 10% Advanced Moisture Complex and 2.1 % of a phosphate modified corn starch derivative known as "Structure Zea”.
- Structure Zea is described in a document identified by the BNSDOClD accession number XP-002339059 issued by National Starch & Chemical, where it is described as a rheology and aesthetics modifier for dilutable powders and emulsion products.
- US-A-2003/0215471 discloses a number of compositions comprising Structure Zea as a rheology modifying agent and Advanced Moisture Complex.
- improved moisturisation properties can be achieved by incorporation into a composition for topical application to the skin of a dimethyl imidazolidinone starch derivative and a polymeric quaternary ammonium salt having humectant properties, and there have hence now been devised improved skincare compositions that exhibit improved, and in particular more long- lasting, and/or more constant, moisturisation effects on the skin.
- the composition may comprise one or more additional moisturising agents, the moisturising effect, and in particular the prolonged moisturisation effect, does not depend on the presence of a large number of complementary moisturising agents.
- compositions for topical application to the skin which composition comprises a starch or starch derivative and a polymeric quaternary ammonium salt having humectant properties, provided that when the starch or starch derivative is a corn starch derivative and the polymeric quaternary ammonium salt is polyquaternium-51 , then the composition does not also comprise glycerin, sodium PCA, urea, trehalose and sodium hyaluronate.
- the composition according to the invention is advantageous primarily in that it exerts a significant moisturisation effect on the skin, and moreover that effect persists for an extended period.
- enhanced and persistent moisturisation of the skin may be achieved by only a small number of applications of the composition each day, perhaps as infrequently as once or twice per day.
- the moisturisation effect may be more constant than effects achieved with other moisturising compositions, which may in turn lead to improved compliance as the skin may not be subject to substantial rises and falls in moisturisation that might influence the frequency of application of the composition.
- the starch or starch derivative is preferably a chemically or physically modified starch. Most preferably, the starch is modified so as to render it heat-stable and/or non-sweiling.
- a preferred form of starch derivative is a dimethyl imidazolidinone starch derivative, ie a product obtained by reaction of 1 ,3-dimethy[-4,5-dihydroxy-2- imidazolidinone (dimethyl imidazolidinone) with starch.
- Particular starches that may be used include corn starch but, more preferably, the starch is rice starch.
- the dimethyl imidazolidinone starch derivative may thus be dimethyiimidazolidinone corn starch or, more preferably, dimethylimidazolidinone rice starch.
- a suitable form of dimethylimidazolidinone rice starch is available from Agrana u. Staerke AG, Conrathstr. 7, A-3950 Gmuend, Austria, under the trade name Rice NS. Another supplier is Dr Hauser, Reintalstrasse 8, D-82467 Garmisch- Partenmaschinen, Germany.
- the starch or starch derivative is preferably present in the composition according to the invention at a level of less than 15% w/w, preferably less than 10% w/w, and more preferably less than 5% w/w.
- the concentration of starch derivative is preferably greater than 0.1% w/w, and more preferably greater than 1% w/w.
- the concentration of starch derivative is therefore preferably in the range 0.1 % to 15% w/w, and more preferably in the range 1 % to 5% w/w, particularly 2.25% to 3.75% w/w.
- the polymeric quaternary ammonium salt is most preferably the material known as Polyquaternium-51 , ie the polymeric quaternary ammonium salt that conforms generally to the formula:
- polyquaternium-51 is available from NOF Corporation, 4-20-3, Ebisu, Shibuya-ku, Tokyo 150, Japan, under the trade name Lipidure-PMB.
- the ammonium salt is preferably present in the composition according to the invention at a level of less than 1% w/w, more preferably less than 0.1% w/w.
- the concentration of ammonium salt is preferably greater than 0.0001 % w/w, and more preferably greater than 0.001 % w/w.
- the concentration of ammonium salt is therefore preferably in the range 0.0001 % to 1 % w/w, and more preferably in the range 0.001% to 0.1% w/w.
- composition according to the invention may comprise one or more additional moisturising or humectant ingredients, ie moisturising or humectant ingredients that are additional to the starch derivative and the ammonium salt.
- the additional moisturising or humectant ingredient is a relatively low molecular weight polyalcohol, eg a C 2 - 6 aliphatic polyalcoho!.
- poiyalcohols include glycerin (1 ,2,3-trihydroxypropane), 1 ,3-butylene glycol and propylene glycol.
- the most preferred additional moisturising or humectant ingredient is glycerin.
- the additional moisturising or humectant ingredient(s) are preferably present in the composition at a level of up to 25% w/w or more, more preferably up to 20% w/w.
- the concentration of additional moisturising or humectant ingredient(s) is preferably greater than 1 % w/w, more preferably greater than 5% w/w, and most preferably greater than 10% w/w.
- the concentration of additional moisturising or humectant ingredient(s) is therefore preferably in the range 1% to 25% w/w, and more preferably in the range 5% to 20% w/w.
- the concentration of glycerin is preferably in the range 1 % to 20% w/w, more preferably in the range 10% to 20% w/w, and in particular in the range 10% to 15% w/w.
- the composition may comprise more than one aliphatic polyalcohol.
- the composition comprises both glycerin and propylene glycol.
- compositions comprising one or more aliphatic polyalcohols have been found to be particularly beneficial.
- the invention thus provides a composition for topical application to the skin, which composition comprises a starch or starch derivative, a polymeric quaternary ammonium salt having humectant properties, and from 10% to 20% w/w of one or more aliphatic polyalcohols.
- the polyalcohols are preferably C 2 -e aliphatic polyalcohols, most preferably selected from the group consisting of glycerin (1 ,2,3-trihydroxypropane), 1 ,3-butylene glycol and propylene glycol.
- the composition comprises glycerin.
- the composition is free of any additional moisturising agents other than the low molecular weight polyalcohols.
- the composition is preferably free of sodium PCA, urea, trehalose and sodium hyaluronate.
- Compositions in accordance with the invention may be formulated in any one of numerous different forms. Suitable types of composition, and methods by which they may be prepared, will generally be evident to those skilled in the art.
- compositions are formulated as emulsions.
- the emulsions may be o/w, w/o, o/w/o or w/o/w emulsions.
- Preferred emulsion compositions are o/w emulsions.
- Such emulsion-type compositions may be described inter alia as creams or lotions.
- Other emulsion compositions are w/o emulsions.
- Another preferred group of compositions are formulated as gels.
- additional ingredients that contribute to improved skin-feel are preferably present.
- additional ingredients may include skin conditioning agents, as well as thickeners, particularly thickeners for the aqueous phase of emulsion compositions.
- Suitable skin conditioning agents include ingredients having emollient properties, ie ingredients which help to maintain the soft, smooth and pliable appearance of the skin, and which function by their ability to remain on the skin surface or in the stratum corneum to act as lubricants, to reduce flaking and to improve the skin's appearance.
- Suitable skin conditioning ingredients will be evident to those skilled in the art, but examples include PPG-15 stearyl ether, ethylhexyl stearate, cetyl dimethicone, octyldodecanoi, PPG-20 methyl glucose ether, isopropyl myristate isopropyl palmitate, isopropyl laurate isodecy!
- Suitable thickeners will also be evident to those skilled in the art, but examples include hydrophiiic polymers and derivatives thereof, eg agarose, carbomer, polyacrylamide, alkyl acrylate crosspolymer, carboxymethyl hydroxyethylceliulose, hydroxyethyl cellulose, xanthan gum, cellulose gum, and hydroxypropyl starch.
- hydrophiiic polymers and derivatives thereof eg agarose, carbomer, polyacrylamide, alkyl acrylate crosspolymer, carboxymethyl hydroxyethylceliulose, hydroxyethyl cellulose, xanthan gum, cellulose gum, and hydroxypropyl starch.
- composition will generally also comprise other ingredients or excipients which constitute or form part of a dermatologically acceptable carrier and will be well known to those skilled in the art. These include, for example:
- Surfactants - anionic surfactants eg sodium lauryl sulphate, sodium laureth sulphate, ammonium laureth sulphate, disodium laureth suifosuccinate and sodium C12-15 pareth sulphate; amphoteric/zwitterionic surfactants, eg coca mido propyl betaine, sodium cocoa mphoacetate and cocamidopropyl hydroxysultaine; nonionic surfactants, eg laureth-3, oleth-5, cocamide DEA, cocamide MEA, PEG-5 cocamide, sucrose cocoate, polysorbate 20, PEG- 40 hydrogenated castor oil; and cationic surfactants, eg cetrimonium chloride, behentrimonium chloride and benzalkonium chloride.
- anionic surfactants eg sodium lauryl sulphate, sodium laureth sulphate, ammonium laureth sulphate, disodium laureth suif
- Emulsifiers eg steareth-2, steareth-21 , steareth-10, ceteareth-5, ceteareth- 12, ceteareth-20, oleth-10, glyceryl stearate, polyglyceryi-3 oleate, polyglyceryl-3 methylglucose distearate, sodium cetearyl sulphate, sodium stearate, PEG-12 Oleate, PEG-2 stearate, PEG-12 stearate, PEG-80 sorbitan, sorbitan oleate, sorbitan palmitate, sorbitan stearate and cetyl PEG/PPG-10/1 dimethicone.
- Emulsifiers eg steareth-2, steareth-21 , steareth-10, ceteareth-5, ceteareth- 12, ceteareth-20, oleth-10, glyceryl stearate, polyglyceryi-3 oleate,
- Chelating agents or sequestering agents (sequestrants) - ingredients that have the ability to complex with and inactivate metallic ions in order to prevent their adverse effects on the stability or appearance of the composition.
- chelating agents are ethylenediamine tetraacetic acid and its salts, notably the dipotassium and especially the disodium or tetrasodium salt.
- Sunscreening agents - inorganic sunscreening agents eg microfine titanium dioxide, microfine zinc oxide, iron oxides, talcs and boron nitride; and/or organic sunscreening agents, eg p-aminobenzoic acids, esters and derivatives thereof, for example, 2-ethylhexyl p-dimethylaminobenzoate and the octyl ester of p-aminobenzoic acid; methoxycinnamate esters such as 2-ethylhexyi p-methoxycinnamate, 2-ethoxyethyl p-methoxycinnamate or ⁇ , ⁇ -di-(p-methoxycinnamoyl)- ⁇ '-(2-ethylhexanoyl)-glycerin; benzophenones such as oxybenzone; 2-phenylbenzimidazole-5-suifonic acid and disodium phenyl dibenzimi
- Preservatives - ingredients which prevent or retard microbial growth and thus protect the composition from spoilage.
- preservatives include DMDM hydantoin, propylparaben, methylparaben, phenoxyethanol, sodium benzoate, bronopol, sodium dehydroacetate, polyhexamethylenebiguanide hydrochloride, isothiazolone and diazolidinylurea.
- compositions according to the invention are useful in that they enhance the moisturisation of the skin.
- a method for moisturising skin comprises the topical application to the skin of a composition comprising a dimethyl imidazolidinone starch derivative and a polymeric quaternary ammonium salt having humectant properties, provided that when the starch or starch derivative is a corn starch derivative and the polymeric quaternary ammonium salt is polyquaternium-51 , then the composition does not also comprise glycerin, sodium PCA, urea, trehalose and sodium hyaluronate.
- the skin to which the composition is applied will most commonly be human skin, • the composition generally being applied by the user to his or her own skin.
- the composition will be applied to areas of skin that are normally exposed, eg the face and/or neck, the arms, hands or legs.
- Phase III Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III: Phase III:
- phase II Add phase I to Il and homogenize. At 60 0 C, add the premix of phase III.
- phase IV and at room temperature mix phase V to the formulation.
- phase Vl adjust the viscosity with phase Vl.
- the baseline values (units of the Corneometer CM 825) of the investigation sites were lower than 40 in the mean. Before the start of the measurements and treatments there was a preconditioning period of 7 days. The analysis of the skin care product in comparison to an untreated investigation site was performed at both volar forearms. Product was applied to the site once at a quantity of 2 ⁇ l/cm 2 . The hydration was measured immediately before starting the product application (t 0 ), and at 2 hours Ct 1 ), 4 hours (t 2 ), 6 hours (t 3 ), 8 hours (t 4 ), 12 hours
- the measured percentage increase in moisturisation relative to baseline is shown as a function of time in Figure 1.
- the Day Cream induced a clear, statistically significant increase in the moisture of the skin during the whole measurement period (24h) after a single application.
- the skin hydration increased until the measurement after 6 hours, peaking at a moisturisation level greater than 40%.
- there was no significant difference between the 4 and 8 hour values and even the 12 hour value was higher than the 2 hour value.
- the moisturisation level was nearly stable over 12 hours with a peak at 6 hours. Even after 24 hours the moisturisation level after single application was more than 20% above baseline.
- One week skin care study The objective of the skin care study was the evaluation of alterations in the skin hydration of one product after a one week treatment regimen compared to untreated skin.
- the baseline values (units of the Corneometer CM 825) of the investigation sites were lower than 40 in the mean. Before the start of the measurements and treatments there was a preconditioning period of 7 days. The analysis of the skin care product in comparison to an untreated investigation site was performed at both volar forearms. Skin hydration was measured immediately before starting the product application (t 0 ). After measurement time point to the Day Cream was applied to one volar forearm in normal quantities by the volunteers themselves, twice daily over a period of one week. The measurements were performed in a climate controlled room at 21.5°C (+/-1°C) and 50% (+/- 5%) relative humidity after the volunteers had adapted themselves to these indoor climate conditions for 30min.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05818617A EP1833457A1 (de) | 2004-12-11 | 2005-12-08 | Hautpflegezusammensetzungen |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0427165A GB0427165D0 (en) | 2004-12-11 | 2004-12-11 | Skincare compositions |
EP05075597 | 2005-03-11 | ||
PCT/GB2005/050239 WO2006061661A1 (en) | 2004-12-11 | 2005-12-08 | Skincare compositions |
EP05818617A EP1833457A1 (de) | 2004-12-11 | 2005-12-08 | Hautpflegezusammensetzungen |
Publications (1)
Publication Number | Publication Date |
---|---|
EP1833457A1 true EP1833457A1 (de) | 2007-09-19 |
Family
ID=35998536
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP05818617A Ceased EP1833457A1 (de) | 2004-12-11 | 2005-12-08 | Hautpflegezusammensetzungen |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP1833457A1 (de) |
WO (1) | WO2006061661A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2439618A (en) * | 2006-06-14 | 2008-01-02 | Reckitt & Colmann Prod Ltd | Skincare composition |
DE102008020797A1 (de) * | 2008-04-22 | 2009-10-29 | Aquyo Cosmetics Gmbh | Hautcreme und deren Verwendung zur Pflege/Behandlung und/oder zur Prophylaxe von Hautschäden vorrangig an den Füßen von Diabetikern |
US8257720B2 (en) | 2009-04-20 | 2012-09-04 | Conopco, Inc. | Stabilized cationic ammonium compounds and compositions comprising the same |
US8324255B2 (en) | 2009-09-15 | 2012-12-04 | Conopco, Inc. | Chelator stabilized cationic ammonium compounds and compositions comprising the same |
US9545366B2 (en) * | 2012-08-30 | 2017-01-17 | L'oreal | Hydrating composition |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5013763A (en) * | 1987-11-30 | 1991-05-07 | The Andrew Jergens Company | Wash-off-resistant skin preparation |
DE19816665A1 (de) * | 1998-04-15 | 1999-10-21 | Henkel Kgaa | Glycolipid-Cremes |
US20030215471A1 (en) * | 2001-01-31 | 2003-11-20 | Wilmott James M. | Surfactant free topical compositions and method for rapid preparation thereof |
-
2005
- 2005-12-08 WO PCT/GB2005/050239 patent/WO2006061661A1/en active Application Filing
- 2005-12-08 EP EP05818617A patent/EP1833457A1/de not_active Ceased
Non-Patent Citations (1)
Title |
---|
See references of WO2006061661A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO2006061661A1 (en) | 2006-06-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US11077049B2 (en) | Long-wearing glossy lipstick | |
US8057786B2 (en) | Cosmetic and dermatological compositions in particular for the treatment of keratin containing substrates | |
GB2439618A (en) | Skincare composition | |
KR19980086669A (ko) | 미세구조 조성물 | |
WO2003002074A1 (fr) | Compositions en emulsion | |
US20070065378A1 (en) | Sunscreen compositions | |
WO2006061661A1 (en) | Skincare compositions | |
JP2013504626A (ja) | コンディショニング剤としてのカチオン性ポリマー | |
US20160235650A1 (en) | Cosmetic Formulation Incorporating a UV-Triggered Self-Healing Material | |
EP2301519A1 (de) | Ultraviolettlicht absorbierende Zusammensetzung | |
JP2002193755A (ja) | フケ・カユミ防止頭髪用および洗髪用化粧料 | |
US20140005131A1 (en) | Active ingredient combinations of glucosyl glycerides and one or more preservatives | |
JP4996408B2 (ja) | 日焼け止め化粧料 | |
US11154477B2 (en) | Use of alkanolamine alkylamides as humectants | |
CN106232091A (zh) | 牛至油及辛酸混合物的抗菌作用 | |
EP3773444B1 (de) | Kosmetische zusammensetzung für eine schnelle schweissverdampfung | |
JP5455292B2 (ja) | 皮膚外用組成物 | |
CA3012025A1 (en) | Synergistic effects of alkanolamine alkylamides and other moisturizing agents | |
JP6686901B2 (ja) | アシル塩基性アミノ酸誘導体および水溶性保湿成分を含有する化粧料組成物 | |
JP2006111580A (ja) | 化粧料 | |
JP2019196338A (ja) | 保湿剤 | |
CN113456542A (zh) | 一种组合物及其应用 | |
JP2002275027A (ja) | 化粧料及び不織布含浸化粧料 | |
JP2003238336A (ja) | 化粧料組成物 | |
US20240216256A1 (en) | Aqueous personal care compositions comprising carboxymethyl cellulose (cmc) having an optimized degree of substitution |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20070619 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR |
|
DAX | Request for extension of the european patent (deleted) | ||
17Q | First examination report despatched |
Effective date: 20100128 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R003 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
|
18R | Application refused |
Effective date: 20120820 |