EP1799557B1 - Double-chamber ampoule - Google Patents

Double-chamber ampoule Download PDF

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Publication number
EP1799557B1
EP1799557B1 EP05771027A EP05771027A EP1799557B1 EP 1799557 B1 EP1799557 B1 EP 1799557B1 EP 05771027 A EP05771027 A EP 05771027A EP 05771027 A EP05771027 A EP 05771027A EP 1799557 B1 EP1799557 B1 EP 1799557B1
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EP
European Patent Office
Prior art keywords
receptacle
dosing chamber
medium
container
constriction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Not-in-force
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EP05771027A
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German (de)
French (fr)
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EP1799557A1 (en
Inventor
Bernd Hansen
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Individual
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Individual
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Priority to PL05771027T priority Critical patent/PL1799557T3/en
Publication of EP1799557A1 publication Critical patent/EP1799557A1/en
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Publication of EP1799557B1 publication Critical patent/EP1799557B1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06—Ampoules or carpules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00—Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
    • B65D1/09—Ampoules
    • B65D1/095—Ampoules made of flexible material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00—Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
    • B65D1/09—Ampoules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents

Definitions

  • the invention relates to a container consisting of a resilient plastic material, with a metering chamber in which a dispensing medium is located, wherein the one end of the metering chamber has a discharge opening and the opposite end is connected via a connection point with a compressible container part, in which a particular gaseous Austreibmedium is located, wherein the compression medium at least partially displaces the discharge medium from the metering chamber via the discharge opening upon compression of the container part.
  • DE-PS 32 44 403 is a generic container made of a resilient plastic material known with a tubular metering chamber in which a material medium is, and which is designed such that the material medium remains independent of the position of the container in the metering chamber and with a squeezable, a gaseous medium containing container part, which has a larger volume than the metering chamber, wherein upon compression of the container part located in the metering material material medium from this metering chamber can be driven by a dispensing opening attachable thereto.
  • the known container solution is used to deliver a material medium of ointment-like consistency at ambient temperature, which is filled in the preparation of the container exclusively in the metering chamber.
  • the ointment-like consistency of the material medium at ambient temperature prevents it from escaping from the tubular metering chamber, which may also be tapered towards the free end of the metering chamber.
  • the gaseous medium is as Ausreibmedium, so that when squeezing the container which is located solely in the dosing chamber material medium is removed substantially from this dosing without practically leaving a residue in the container.
  • the known solution finds its limitation insofar as for dispensing media in the metering chamber with low viscosity compared to the ointment-like consistency, the discharge medium from the metering chamber via the extension as a junction enters the container part, there mixed with the Austreibmedium and thus the container solution can be unusable.
  • a container made of plastic for a dispensable dispensing of flowable substances has been proposed, with a provided at one end discharge opening and an adjoining the other open end, and only to the interior of the container open chamber whose volume is reduced by a manual deformation, and which is formed integrally with the container, wherein the container is formed as a cylinder and wherein the flowable substance receiving interior of the cylinder is separated from the interior of the chamber by a longitudinally displaceable in the cylinder by hand separating piston, wherein in the chamber air is stored, the hand displaces the separating piston against the discharge opening of the container suppressed.
  • the material separation of the discharge medium in the metering chamber to Austreibmedium in the container part is achieved in the known solution, so that it does not unintentionally come to mixtures insofar as the container solution could be unusable.
  • the known container solution it is also possible to dispense very thin-bodied dispensing media, but with the disadvantage that, due to the separating piston, the known solution is expensive to produce and in particular builds up axially large in dispensing direction.
  • the present invention seeks to provide a container that is inexpensive to produce, constructively small and can build, it allows, without much design effort as delivery media such thin consistency and / or in the manner of an aerosol deploy.
  • This object is achieved by a container having the features of claim 1 in its entirety.
  • connection point between metering chamber and container part is formed from a constriction, which is designed such that a capillary effect is formed, regardless of the spatial position of the container, a transfer of the delivery medium from the metering chamber into the container part prevented with the Austreibmedium, it is ensured that even without Trennkolbenanowski the discharge medium can not accidentally flow from the metering chamber in the direction of the container part with the Austreibmedium.
  • the reliability is ensured in any case and it is surprising for a person of ordinary skill in the field of manufacturing pertinent container that he thus also sprayable as a release medium Aerosols od.
  • Can deploy The latter substances are becoming increasingly important in pharmacy, because there is the possibility of bringing sprayable active ingredients into contact with the nasal mucous membrane, in order to ensure a rapid absorption of active substance, which is not guaranteed in the case of intake of a different kind.
  • the constriction is formed from a capillary tube. Furthermore, it is preferably provided that the vulnerable bottleneck is stiffened by means of a support device. With the pertinent support device ensures that the bottleneck can not be accidentally damaged or compressed, which could damage their function.
  • the support means comprises at least two web-like support arms, which comprise both at least parts of the container part, the bottleneck and the metering chamber.
  • the two support arms extend along a parting plane and at least partially cover it, along which the parts of the container abut in half. In addition to the already mentioned stiffening of the overall container, this also allows an improved sealing of the container contents relative to the environment, so that the sterility of the container interior is ensured even over a long period of time.
  • the container according to the invention go in extension of the container part on its side facing away from the dosing chamber, the two support arms in a provided with a coding terminal lug on.
  • coding can be a container identification obtained in particular based on its contents.
  • the dosing chamber tapers toward the discharge opening, at least in stages, conically.
  • the degree of the selected conical taper results in such a way when expressing the container, an increase in speed for the stored medium, which positively affects its output.
  • an increased beam effect can be achieved.
  • the container shown in the figures consists of a transparent, elastically yielding plastic material which alone (see. Fig.1 and 2 ) or together with other containers (cf. Figure 3 ) Can be produced by means of a blow molding machine, filled and sterile closable.
  • the container has a tubular metering chamber 10, which is closed at its lower end in the drawing by a toggle closure 12 having a constricted predetermined breaking point 14 and a handle 16 for twisting the toggle closure 12 so as to release the discharge port 18 at the lower end of the metering chamber 10.
  • the dosing chamber 10 is a release medium, for example, such an ointment-like consistency, such as an eye ointment;
  • the delivery medium consists of such a low viscosity, also in the form of an aerosol, which can be dispensed from the dosing chamber 10 via the discharge opening 18 from the container in the manner of a spray or spray process.
  • the tubular structure of the metering chamber 10 would allow such good insertion into a body opening, such as a nostril od. Like., Allow.
  • the opposite end of the metering chamber 10 is connected via a connection point 20 with a compressible container part 22, in which a particular gaseous Austreibmedium, for example in the form of air, is located.
  • a compressible container part 22 in which a particular gaseous Austreibmedium, for example in the form of air, is located.
  • the expelling medium at least partially displaces the dispensing medium out of the dosing chamber 10 via the dispensing opening 18 for an application process outwards into the environment.
  • connection point 20 between the dosing chamber 10 and the container part 22 is formed from a constriction according to the figurative representation, wherein the constriction is formed such that a capillary effect is formed, regardless of the spatial position of the container, a transfer of the discharge medium from the metering chamber into the container part 22nd prevented with the Austreibmedium.
  • the Austreibmedium not squeeze unintentionally through the junction 20 in the direction of the dosing chamber 10 without squeezing the container part.
  • the bottleneck formed from a capillary tube, which is arranged in the manner of a constriction in the transition region between metering chamber 10 and container part 22.
  • the axial extent of the capillary tube along the parting plane 24 of the container is smaller than its free passage cross section for the delivery medium.
  • the vulnerable bottleneck is stiffened by means of a support device designated as a whole by 26.
  • the support means 26 has two web-like support arms 28,30, which include both the container part 22, the junction 20 and at least the lower third of the metering chamber 10.
  • the particular Fig. 2 shows extend the two support arms 28,30 along said parting plane 24 and cover them in the frame described above, at least partially, so that at the point along which the parts of the container manufacturing technology in half abut each other, achieved an additional seal on the support means 26 is.
  • At her in the direction of the Fig.1 seen lower end go the two support arms 28,30 via a conical inlet section in one piece into the dosing chamber 10 via.
  • the two support arms 28,30 open in a flat, square terminal lug 32.
  • the terminal lug 32 also allows to attach a coding 34 so as to identify the container and its contents .
  • the height of the terminal lug 32 is chosen such that it according to the illustration of the Fig.2 projecting beyond the dividing plane 24 with the support device 26 with a marginal projection.
  • the terminal lug 32 via another Predetermined breaking point 36 are separated from the container part 22.
  • the container part 22 is configured substantially cuboid and has, according to the illustration of the Fig.2 on opposite sides of two contact surfaces 38, which allow the compression of the container part 22 by hand, for example with the thumb and forefinger of an operator.
  • the abutment surfaces 38 in turn extend parallel to the parting plane 24.
  • the abutment surfaces 38 are clearly projected in both directions over the upper side of the metering chamber 10.
  • the volume ratios of container part 22 to dosing chamber 10 are about 2: 1, in order to be able to ensure a complete media discharge via the discharge opening 18 in this way.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Ceramic Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Physical Deposition Of Substances That Are Components Of Semiconductor Devices (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Containers Having Bodies Formed In One Piece (AREA)
  • Packaging Frangible Articles (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

A receptacle of an elastically flexible plastic includes a dosing chamber (10) with a medium to be discharged. One end of the dosing chamber (10) has a discharge opening (18). The opposite end is connected via a junction point (20) to a compressible receptacle part (22) with a gaseous propelling medium. When compressing the receptacle part (22), the propelling medium forces the medium to be discharged out of the dosing chamber (10) via the discharge opening (18). The junction point (20) between the dosing chamber (10) and the receptacle part (22) is a bottleneck creating a capillary effect independent of the spatial position of the receptacle preventing transfer of the medium of the dosing chamber (10) into the receptacle part (22).

Description

Die Erfindung betrifft einen Behälter, bestehend aus einem elastisch nachgiebigen Kunststoffmaterial, mit einer Dosierkammer, in der sich ein Abgabemedium befindet, wobei das eine Ende der Dosierkammer eine Abgabeöffnung aufweist und das gegenüberliegende Ende ist über eine Verbindungsstelle mit einem zusammendrückbaren Behälterteil verbunden, in dem sich ein insbesondere gasförmiges Austreibmedium befindet, wobei beim Zusammendrücken des Behälterteils das Austreibmedium zumindest teilweise das Abgabemedium aus der Dosierkammer über die Abgabeöffnung verdrängt.The invention relates to a container consisting of a resilient plastic material, with a metering chamber in which a dispensing medium is located, wherein the one end of the metering chamber has a discharge opening and the opposite end is connected via a connection point with a compressible container part, in which a particular gaseous Austreibmedium is located, wherein the compression medium at least partially displaces the discharge medium from the metering chamber via the discharge opening upon compression of the container part.

Durch die DE-PS 32 44 403 ist ein gattungsgemäßer Behälter aus einem elastischen Kunststoffmaterial bekannt mit einer rohrförmigen Dosierkammer, in der sich ein stoffliches Medium befindet, und die derart ausgebildet ist, dass das stoffliche Medium unabhängig von der Lage des Behälters in der Dosierkammer verbleibt und mit einem zusammendrückbaren, ein gasförmiges Medium enthaltenden Behälterteil, der ein größeres Volumen als die Dosierkammer hat, wobei beim Zusammendrücken des Behälterteils das in der Dosierkammer befindliche stoffliche Medium aus dieser Dosierkammer durch eine daran anbringbare Abgabeöffnung austreibbar ist.By the DE-PS 32 44 403 is a generic container made of a resilient plastic material known with a tubular metering chamber in which a material medium is, and which is designed such that the material medium remains independent of the position of the container in the metering chamber and with a squeezable, a gaseous medium containing container part, which has a larger volume than the metering chamber, wherein upon compression of the container part located in the metering material material medium from this metering chamber can be driven by a dispensing opening attachable thereto.

Die bekannte Behälterlösung dient der Abgabe eines stofflichen Mediums von bei Umgebungstemperatur salbenartiger Konsistenz, das bei der Herstellung des Behälters ausschließlich in die Dosierkammer gefüllt wird. Die bei Umgebungstemperatur salbenartige Konsistenz des stofflichen Mediums verhindert dessen Austreten aus der rohrförmigen Dosierkammer, die auch zum freien Ende der Dosierkammer hin kegelförmig ausgebildet sein kann. In dem bekannten Behälterteil befindet sich nur das gasförmige Medium als Austreibmedium, so dass beim Zusammendrücken des Behälters das allein in der Dosierkammer befindliche stoffliche Medium im wesentlichen aus dieser Dosierkammer entfernt wird, ohne dass praktisch ein Rest im Behälter zurückbleibt. Die bekannte Lösung findet insofern ihre Einschränkung, als bei Abgabemedien in der Dosierkammer mit niedriger Viskosität gegenüber der salbenartigen Konsistenz das Abgabemedium von der Dosierkammer über die Erweiterung als Verbindungsstelle in das Behälterteil eintritt, sich dort mit dem Austreibmedium vermischt und insofern die Behälterlösung unbrauchbar werden läßt.The known container solution is used to deliver a material medium of ointment-like consistency at ambient temperature, which is filled in the preparation of the container exclusively in the metering chamber. The ointment-like consistency of the material medium at ambient temperature prevents it from escaping from the tubular metering chamber, which may also be tapered towards the free end of the metering chamber. In the known container part, only the gaseous medium is as Ausreibmedium, so that when squeezing the container which is located solely in the dosing chamber material medium is removed substantially from this dosing without practically leaving a residue in the container. The known solution finds its limitation insofar as for dispensing media in the metering chamber with low viscosity compared to the ointment-like consistency, the discharge medium from the metering chamber via the extension as a junction enters the container part, there mixed with the Austreibmedium and thus the container solution can be unusable.

Um diesem Nachteil zu begegnen, ist gemäß der DE 44 20 594 C2 ein Behältnis aus Kunststoff für eine dosierbare Abgabe von fließfähigen Stoffen vorgeschlagen worden, mit einer am einen Ende vorgesehenen Abgabeöffnung und einer sich an das andere offene Ende anschließenden, und nur zum Inneren des Behälters hin offenen Kammer, deren Volumen durch eine manuelle Deformation reduzierbar ist, und die einstückig mit dem Behältnis ausgebildet ist, wobei das Behältnis als ein Zylinder ausgebildet ist und wobei der den fließfähigen Stoff aufnehmende Innenraum des Zylinders vom Innenraum der Kammer durch einen im Zylinder von Hand längsverschiebbaren Trennkolben getrennt ist, wobei in der Kammer Luft bevorratet ist, die von Hand verdrängt den Trennkolben gegen die Abgabeöffnung des Behältnisses drückt. Durch den genannten Trennkolben ist bei der bekannten Lösung die stoffliche Trennung von Abgabemedium in der Dosierkammer zu Austreibmedium im Behälterteil erreicht, so dass es insoweit nicht ungewollt zu Vermischungen kommt, was die Behälterlösung unbrauchbar werden lassen könnte. Mit der bekannten Behälterlösung ist es möglich, mithin auch sehr dünnflüssige Abgabemedien auszubringen, jedoch mit dem Nachteil, dass aufgrund des Trennkolbens die bekannte Lösung teuer in der Herstellung ist und insbesondere in Abgaberichtung axial groß aufbaut.To address this disadvantage is, according to the DE 44 20 594 C2 a container made of plastic for a dispensable dispensing of flowable substances has been proposed, with a provided at one end discharge opening and an adjoining the other open end, and only to the interior of the container open chamber whose volume is reduced by a manual deformation, and which is formed integrally with the container, wherein the container is formed as a cylinder and wherein the flowable substance receiving interior of the cylinder is separated from the interior of the chamber by a longitudinally displaceable in the cylinder by hand separating piston, wherein in the chamber air is stored, the hand displaces the separating piston against the discharge opening of the container suppressed. By the said separating piston, the material separation of the discharge medium in the metering chamber to Austreibmedium in the container part is achieved in the known solution, so that it does not unintentionally come to mixtures insofar as the container solution could be unusable. With the known container solution, it is also possible to dispense very thin-bodied dispensing media, but with the disadvantage that, due to the separating piston, the known solution is expensive to produce and in particular builds up axially large in dispensing direction.

Ein anderer derartiger Behälter für eine dosierbare Abgabe mit den Merkmalen des Oberbegriffs des Anspruch 1 ist aus der dokument US5582330 bekannt.Another such container for a metered dispensing with the features of the preamble of claim 1 is from the document US5582330 known.

Ausgehend von diesem Stand der Technik liegt der Erfindung die Aufgabe zugrunde, einen Behälter zu schaffen, der kostengünstig herstellbar ist, konstruktiv klein aufbauen kann und der es erlaubt, ohne großen konstruktiven Aufwand als Abgabemedien solche auch dünnflüssiger Konsistenz und/oder in der Art eines Aerosols auszubringen. Eine dahingehende Aufgabe löst ein Behälter mit den Merkmalen des Patentanspruches 1 in seiner Gesamtheit.Based on this prior art, the present invention seeks to provide a container that is inexpensive to produce, constructively small and can build, it allows, without much design effort as delivery media such thin consistency and / or in the manner of an aerosol deploy. This object is achieved by a container having the features of claim 1 in its entirety.

Dadurch, dass gemäß dem kennzeichnenden Teil des Patentanspruches 1 die Verbindungsstelle zwischen Dosierkammer und Behälterteil aus einer Engstelle gebildet ist, die derart ausgestaltet ist, dass eine Kapillarwirkung entsteht, die unabhängig von der räumlichen Lage des Behälters einen Übertritt des Abgabemediums aus der Dosierkammer in den Behälterteil mit dem Austreibmedium verhindert, ist sichergestellt, dass auch ohne Trennkolbenanordnung das Abgabemedium nicht ungewollt von der Dosierkammer in Richtung des Behälterteils mit dem Austreibmedium strömen kann. Unabhängig von der räumlichen Anordnung des Behälters ist somit die Funktionssicherheit in jedem Fall sichergestellt und es ist für einen Durchschnittsfachmann auf dem Gebiet der Herstellung dahingehender Behälter überraschend, dass er dergestalt als Abgabemedium auch verspraybare Aerosole od. dgl. ausbringen kann. Letztere Stoffe bekommen zusehends Bedeutung in der Pharmazie, denn es besteht dergestalt die Möglichkeit, verspraybare Wirkstoffe mit der Nasenschleimhaut in Verbindung zu bringen, um dergestalt eine rasche Wirkstoffaufnahme zu gewährleisten, was bei einer Aufnahme anderer Art nicht gewährleistet ist.Characterized in that according to the characterizing part of claim 1, the connection point between metering chamber and container part is formed from a constriction, which is designed such that a capillary effect is formed, regardless of the spatial position of the container, a transfer of the delivery medium from the metering chamber into the container part prevented with the Austreibmedium, it is ensured that even without Trennkolbenanordnung the discharge medium can not accidentally flow from the metering chamber in the direction of the container part with the Austreibmedium. Regardless of the spatial arrangement of the container thus the reliability is ensured in any case and it is surprising for a person of ordinary skill in the field of manufacturing pertinent container that he thus also sprayable as a release medium Aerosols od. Like. Can deploy. The latter substances are becoming increasingly important in pharmacy, because there is the possibility of bringing sprayable active ingredients into contact with the nasal mucous membrane, in order to ensure a rapid absorption of active substance, which is not guaranteed in the case of intake of a different kind.

Bei einer bevorzugten Ausführungsform des erfindungsgemäßen Behälters ist die Engstelle aus einem Kapillarröhrchen gebildet. Ferner ist vorzugsweise vorgesehen, dass die verletzliche Engstelle mittels einer Stützeinrichtung ausgesteift ist. Mit der dahingehenden Stützeinrichtung ist sichergestellt, dass die Engstelle nicht ungewollt beschädigt oder zusammengedrückt werden kann, was deren Funktion schädigen könnte.In a preferred embodiment of the container according to the invention, the constriction is formed from a capillary tube. Furthermore, it is preferably provided that the vulnerable bottleneck is stiffened by means of a support device. With the pertinent support device ensures that the bottleneck can not be accidentally damaged or compressed, which could damage their function.

Bei einer bevorzugten Ausführungsform des erfindungsgemäßen Behälters weist die Stützeinrichtung mindestens zwei stegartige Stützarme auf, die sowohl zumindest Teile des Behälterteils, der Engstelle als auch der Dosierkammer umfassen. Vorzugsweise erstrecken sich dabei die beiden Stützarme längs einer Trennebene und überdecken diese zumindest teilweise, längs der die Teile des Behälters hälftig aneinanderstoßen. Neben der bereits angesprochenen Aussteifung des Gesamtbehälters erlaubt dies auch eine verbesserte Abdichtung des Behälterinhalts gegenüber der Umgebung, so dass auch über längere Zeit die Sterilität des Behälterinneren gewährleistet ist.In a preferred embodiment of the container according to the invention, the support means comprises at least two web-like support arms, which comprise both at least parts of the container part, the bottleneck and the metering chamber. Preferably, the two support arms extend along a parting plane and at least partially cover it, along which the parts of the container abut in half. In addition to the already mentioned stiffening of the overall container, this also allows an improved sealing of the container contents relative to the environment, so that the sterility of the container interior is ensured even over a long period of time.

Bei einer weiteren bevorzugten Ausführungsform des erfindungsgemäßen Behälters gehen in Verlängerung des Behälterteils an seiner der Dosierkammer abgewandten Seite die beiden Stützarme in eine mit einer Kodierung versehene Anschlußfahne über. Mittels der angesprochenen Kodierung läßt sich eine Behälteridentifikation insbesondere bezogen auf seinen Inhalt erhalten.In a further preferred embodiment of the container according to the invention go in extension of the container part on its side facing away from the dosing chamber, the two support arms in a provided with a coding terminal lug on. By means of the mentioned coding can be a container identification obtained in particular based on its contents.

Bei einer weiteren, besonders bevorzugten Ausführungsform des erfindungsgemäßen Behälters verjüngt sich die Dosierkammer zur Abgabeöffnung hin zumindest stufenweise konisch. Je nach Grad der gewählten konischen Verjüngung ergibt sich dergestalt beim Ausdrücken des Behälters eine Geschwindigkeitserhöhung für das bevorratete Medium, was seine Ausbringung positiv beeinflußt. Insbesondere kann bei der Abgabe eine erhöhte Strahlwirkung erreicht werden.In a further, particularly preferred embodiment of the container according to the invention, the dosing chamber tapers toward the discharge opening, at least in stages, conically. Depending on the degree of the selected conical taper results in such a way when expressing the container, an increase in speed for the stored medium, which positively affects its output. In particular, in the delivery of an increased beam effect can be achieved.

Weitere vorteilhafte Ausführungsformen des erfindungsgemäßen Behälters sind Gegenstand der weiteren Unteransprüche.Further advantageous embodiments of the container according to the invention are the subject of the further subclaims.

Im folgenden wird der erfindungsgemäße Behälter anhand eines Ausführungsbeispiels nach der Zeichnung näher erläutert. Dabei zeigen in prinzipieller und nicht maßstäblicher Darstellung die

Fig.1
eine Draufsicht auf den erfindungsgemäßen Behälter;
Fig.2
eine Seitenansicht auf den Behälter nach der Fig.1 und
Fig.3
mehrere, zu einer Gruppe zusammengefaßte vereinzelbare Behälter gemäß der Ausgestaltung nach den Fig.1 und 2.
In the following the container according to the invention is explained in more detail using an exemplary embodiment according to the drawing. This show in principle and not to scale representation of the
Fig.1
a plan view of the container according to the invention;
Fig.2
a side view of the container after the Fig.1 and
Figure 3
a plurality of individualized containers combined into a group according to the embodiment according to FIGS Fig.1 and 2 ,

Der in den Figuren dargestellte Behälter besteht aus einem durchsichtigen, elastisch nachgiebigen Kunststoffmaterial, der allein (vgl. Fig.1 und 2) oder zusammen mit anderen Behältern (vgl. Fig.3) mittels einer Blasformmaschine herstellbar, befüllbar und steril verschließbar ist. Der Behälter weist eine rohrförmige Dosierkammer 10 auf, die an ihrem in der Zeichnung gesehen unteren Ende durch einen Knebelverschluß 12 verschlossen ist, der eine eingeschnürte Sollbruchstelle 14 und eine Handhabe 16 aufweist zum Abdrehen des Knebelverschlusses 12, um dergestalt die Abgabeöffnung 18 am unteren Ende der Dosierkammer 10 freizugeben. In der Dosierkammer 10 befindet sich ein Abgabemedium, beispielsweise ein solches mit salbenartiger Konsistenz, wie eine Augensalbe; vorzugsweise besteht das Abgabemedium jedoch aus einem solchen niederer Viskosität, auch in Form eines Aerosols, das sich in der Art eines Spray- oder Sprühvorganges aus der Dosierkammer 10 über die Abgabeöffnung 18 aus dem Behälter ausbringen läßt. Der röhrenförmige Aufbau der Dosierkammer 10 würde dergestalt eine gute Einbringbarkeit in eine Körperöffnung, wie eine Nasenöffnung od. dgl., ermöglichen.The container shown in the figures consists of a transparent, elastically yielding plastic material which alone (see. Fig.1 and 2 ) or together with other containers (cf. Figure 3 ) Can be produced by means of a blow molding machine, filled and sterile closable. The container has a tubular metering chamber 10, which is closed at its lower end in the drawing by a toggle closure 12 having a constricted predetermined breaking point 14 and a handle 16 for twisting the toggle closure 12 so as to release the discharge port 18 at the lower end of the metering chamber 10. In the dosing chamber 10 is a release medium, for example, such an ointment-like consistency, such as an eye ointment; Preferably, however, the delivery medium consists of such a low viscosity, also in the form of an aerosol, which can be dispensed from the dosing chamber 10 via the discharge opening 18 from the container in the manner of a spray or spray process. The tubular structure of the metering chamber 10 would allow such good insertion into a body opening, such as a nostril od. Like., Allow.

Das gegenüberliegende Ende der Dosierkammer 10 ist über eine Verbindungsstelle 20 mit einem zusammendrückbaren Behälterteil 22 verbunden, in dem sich ein insbesondere gasförmiges Austreibmedium, beispielsweise in Form von Luft, befindet. Beim Zusammendrücken des Behälterteils 22, vorzugsweise von Hand, verdrängt das Austreibmedium zumindest teilweise das Abgabemedium aus der Dosierkammer 10 über die Abgabeöffnung 18 für einen Applizierungsvorgang nach außen in die Umgebung. Die Verbindungsstelle 20 zwischen Dosierkammer 10 und Behälterteil 22 ist aus einer Engstelle gemäß der figürlichen Darstellung gebildet, wobei die Engstelle derart ausgebildet ist, dass eine Kapillarwirkung entsteht, die unabhängig von der räumlichen Lage des Behälters einen Übertritt des Abgabemediums aus der Dosierkammer in den Behälterteil 22 mit dem Austreibmedium verhindert. Ebenso kann das Austreibmedium ohne Zusammendrücken des Behälterteils 22 nicht ungewollt über die Verbindungsstelle 20 in Richtung der Dosierkammer 10 austreten. Insbesondere ist die Engstelle aus einem Kapillarröhrchen gebildet, das in der Art einer Einschnürstelle im Übergangsbereich zwischen Dosierkammer 10 und Behälterteil 22 angeordnet ist. Die axiale Erstreckung des Kapillarröhrchens entlang der Trennebene 24 des Behälters ist jedenfalls kleiner als sein freier Durchtrittsquerschnitt für das Abgabemedium.The opposite end of the metering chamber 10 is connected via a connection point 20 with a compressible container part 22, in which a particular gaseous Austreibmedium, for example in the form of air, is located. When the container part 22 is compressed, preferably by hand, the expelling medium at least partially displaces the dispensing medium out of the dosing chamber 10 via the dispensing opening 18 for an application process outwards into the environment. The connection point 20 between the dosing chamber 10 and the container part 22 is formed from a constriction according to the figurative representation, wherein the constriction is formed such that a capillary effect is formed, regardless of the spatial position of the container, a transfer of the discharge medium from the metering chamber into the container part 22nd prevented with the Austreibmedium. Likewise, the Austreibmedium not squeeze unintentionally through the junction 20 in the direction of the dosing chamber 10 without squeezing the container part. In particular, the bottleneck formed from a capillary tube, which is arranged in the manner of a constriction in the transition region between metering chamber 10 and container part 22. In any case, the axial extent of the capillary tube along the parting plane 24 of the container is smaller than its free passage cross section for the delivery medium.

Wie die Figuren weiter zeigen, ist die verletzliche Engstelle mittels einer als Ganzes mit 26 bezeichneten Stützeinrichtung ausgesteift. Wie insbesondere die Fig.1 zeigt, weist die Stützeinrichtung 26 zwei stegartige Stützarme 28,30 auf, die sowohl den Behälterteil 22, die Verbindungsstelle 20 als auch zumindest das untere Drittel der Dosierkammer 10 umfassen. Wie insbesondere die Fig. 2 zeigt, erstrecken sich dabei die beiden Stützarme 28,30 längs der genannten Trennebene 24 und überdecken diese im vorstehend beschriebenen Rahmen zumindest teilweise, so dass an der Stelle, längs der die Teile des Behälters fertigungstechnisch hälftig aneinanderstoβen, eine zusätzliche Abdichtung über die Stützeinrichtung 26 erreicht ist. An ihrem in Blickrichtung auf die Fig.1 gesehen unteren Ende gehen die beiden Stützarme 28,30 über eine konische Zulaufstrecke einstückig in die Dosierkammer 10 über.As the figures further show, the vulnerable bottleneck is stiffened by means of a support device designated as a whole by 26. How the particular Fig.1 shows, the support means 26 has two web-like support arms 28,30, which include both the container part 22, the junction 20 and at least the lower third of the metering chamber 10. How the particular Fig. 2 shows, extend the two support arms 28,30 along said parting plane 24 and cover them in the frame described above, at least partially, so that at the point along which the parts of the container manufacturing technology in half abut each other, achieved an additional seal on the support means 26 is. At her in the direction of the Fig.1 seen lower end go the two support arms 28,30 via a conical inlet section in one piece into the dosing chamber 10 via.

In Verlängerung des Behälterteils 22 in Blickrichtung auf die Fig. 1 und 2 gesehen nach oben hin, münden die beiden Stützarme 28,30 in einer flächig ausgebildeten, quadratischen Anschlußfahne 32. Neben einer verbesserten Handhabung für den Behälter erlaubt die Anschlußfahne 32 darüber hinaus, eine Kodierung 34 anzubringen, um dergestalt den Behälter und seinen Inhalt identifizieren zu können. Die Höhe der Anschlußfahne 32 ist derart gewählt, dass sie gemäß der Darstellung nach der Fig.2 mit einem randseitigen Überstand über die Trennebene 24 mit der Stützeinrichtung 26 vorsteht. Gegebenenfalls könnte die Anschlußfahne 32 über eine weitere Sollbruchstelle 36 auch vom Behälterteil 22 abgetrennt werden. Im Gegensatz zu der Dosierkammer 10, die röhrenförmig ausgebildet ist, ebenso wie die Verbindungsstelle 20 in Form der Engstelle, ist das Behälterteil 22 im wesentlichen quaderförmig ausgestaltet und weist gemäß der Darstellung nach der Fig.2 auf gegenüberliegenden Seiten zwei Anlageflächen 38 auf, die das Zusammendrücken des Behälterteils 22 von Hand, beispielsweise mit Daumen und Zeigefinger einer Bedienperson, ermöglichen. Ferner erstrecken sich die Anlageflächen 38 wiederum parallel zur Trennebene 24. Insbesondere stehen die Anlageflächen 38 dergestalt in beiden Richtungen über die Oberseite der Dosierkammer 10 deutlich hervor. Ferner betragen die Volumenverhältnisse von Behälterteil 22 zu Dosierkammer 10 etwa 2 : 1, um dergestalt einen vollständigen Medienaustrag über die Abgabeöffnung 18 sicherstellen zu können.In extension of the container part 22 in the direction of the Fig. 1 and 2 seen in the upward direction, the two support arms 28,30 open in a flat, square terminal lug 32. In addition to improved handling for the container, the terminal lug 32 also allows to attach a coding 34 so as to identify the container and its contents , The height of the terminal lug 32 is chosen such that it according to the illustration of the Fig.2 projecting beyond the dividing plane 24 with the support device 26 with a marginal projection. Optionally, the terminal lug 32 via another Predetermined breaking point 36 are separated from the container part 22. In contrast to the metering chamber 10, which is tubular, as well as the connection point 20 in the form of the constriction, the container part 22 is configured substantially cuboid and has, according to the illustration of the Fig.2 on opposite sides of two contact surfaces 38, which allow the compression of the container part 22 by hand, for example with the thumb and forefinger of an operator. In addition, the abutment surfaces 38 in turn extend parallel to the parting plane 24. In particular, the abutment surfaces 38 are clearly projected in both directions over the upper side of the metering chamber 10. Furthermore, the volume ratios of container part 22 to dosing chamber 10 are about 2: 1, in order to be able to ensure a complete media discharge via the discharge opening 18 in this way.

Bei der Darstellung nach der Fig.3 sind mehrere Behälter, in an sich bekannter Weise, an ihren einander zugewandten Seiten in Aufeinanderfolge miteinander verbunden, wobei die derart in Reihe von der Blasformmaschine hergestellten Behälter über ihre aneinandergrenzenden Stirnseiten voneinander abtrennbar sind. Dergestalt besteht für einen Anwender die Möglichkeit, in Gruppen zusammengestellte Behälter, beispielsweise ein Wochenvorrat, einzeln zu separieren und anzuwenden. Über den dahingehenden Verbund läßt sich dergestalt auch Verpackungsmaterial einsparen.In the presentation after the Figure 3 a plurality of containers, in a conventional manner, connected to each other on their sides facing each other in succession, wherein the thus produced in series by the blow molding machine can be separated from each other via their adjacent end faces. In this way, it is possible for a user to individually separate and apply containers put together in groups, for example a weekly supply. About the pertinent composite can also be saved packaging material.

Mit der erfindungsgemäßen Behälterlösung steht zu erwarten, dass die Anwendungsmöglichkeiten für die beschriebenen Medienabgaben bei Patienten steigen werden.With the container solution according to the invention, it is to be expected that the application possibilities for the described media deliveries in patients will increase.

Claims (11)

  1. A receptacle made of an elastically flexible plastic material, comprising a dosing chamber (10) in which a delivery medium is located, one end of the dosing chamber (10) having a discharge opening (18), and the opposite end being connected to a compressible receptacle part (22) by means of a connecting point (20) in which there is an especially gaseous propellant medium, when the receptacle part (22) is compressed the propellant medium at least partially displacing the delivery medium out of the dosing chamber (10) via the discharge opening (18), characterised in that the connecting point (20) between the dosing chamber (10) and the receptacle part (22) is formed from a constriction which is designed such that a capillary action is produced which, independently of the spatial location of the receptacle, prevents overflow of the delivery medium from the dosing chamber (10) into the receptacle part (22) with the propellant medium.
  2. The receptacle according to Claim 1, characterised in that the constriction is formed from a capillary tube.
  3. The receptacle according to Claim 1 or 2, characterised in that the vulnerable constriction is stiffened by means of a support device (26).
  4. The receptacle according to Claim 2, characterised in that the support device (26) has at least two crosspiece-like support arms (28, 30) which encompass at least parts of the receptacle part (22), the constriction and the dosing chamber (10).
  5. The receptacle according to Claim 4, characterised in that the two support arms (28, 30) extend along a separating plane (24) and at least partially overlap the latter, along which the parts of the receptacle half abut one another.
  6. The receptacle according to either of Claims 4 or 5, characterised in that in an extension of the receptacle part (22) on its side facing away from the dosing chamber (10) the two support arms (28, 30) undergo transition into a tab (32) which is provided with coding (34).
  7. The receptacle according to any of Claims 1 to 6, characterised in that the dosing chamber (10) and the constriction are tubular in form, and the receptacle part (22) is substantially quadrangular in form.
  8. The receptacle according to Claim 7, characterised in that the quadrangular receptacle part (22) projects at least in one direction over the top of the dosing chamber (10).
  9. The receptacle according to any of Claims 1 to 8, characterised in that the ratio of the volumes of the receptacle part (22) to the dosing chamber (10) is at least 2 : 1.
  10. The receptacle according to any of Claims 1 to 9, characterised in that the discharge opening (18) is closed by means of a twist closure (12) before discharging the delivery medium.
  11. The receptacle according to any of Claims 1 to 10, characterised in that the dosing chamber (10) tapers conically, at least in increments, toward the discharge opening (18).
EP05771027A 2004-09-21 2005-07-26 Double-chamber ampoule Not-in-force EP1799557B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL05771027T PL1799557T3 (en) 2004-09-21 2005-07-26 Double-chamber ampoule

Applications Claiming Priority (2)

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DE102004046536A DE102004046536A1 (en) 2004-09-21 2004-09-21 container
PCT/EP2005/008093 WO2006032320A1 (en) 2004-09-21 2005-07-26 Double-chamber ampoule

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EP1799557A1 EP1799557A1 (en) 2007-06-27
EP1799557B1 true EP1799557B1 (en) 2011-07-06

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US (1) US8551053B2 (en)
EP (1) EP1799557B1 (en)
JP (1) JP4922171B2 (en)
KR (1) KR101182691B1 (en)
CN (1) CN101001784B (en)
AT (1) ATE515446T1 (en)
AU (1) AU2005287690B2 (en)
BR (1) BRPI0515481B1 (en)
CA (1) CA2573402C (en)
DE (1) DE102004046536A1 (en)
DK (1) DK1799557T3 (en)
ES (1) ES2365718T3 (en)
HK (1) HK1105140A1 (en)
MX (1) MX2007003346A (en)
PL (1) PL1799557T3 (en)
PT (1) PT1799557E (en)
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CN101001784A (en) 2007-07-18
BRPI0515481B1 (en) 2017-02-07
KR20070057774A (en) 2007-06-07
US8551053B2 (en) 2013-10-08
CA2573402A1 (en) 2006-03-30
ES2365718T3 (en) 2011-10-10
PT1799557E (en) 2011-07-25
WO2006032320A1 (en) 2006-03-30
JP4922171B2 (en) 2012-04-25
EP1799557A1 (en) 2007-06-27
DK1799557T3 (en) 2011-09-26
US20080275404A1 (en) 2008-11-06
DE102004046536A1 (en) 2006-03-30
AU2005287690B2 (en) 2011-08-11
JP2008513303A (en) 2008-05-01
BRPI0515481A (en) 2008-07-22
KR101182691B1 (en) 2012-09-17
AU2005287690A1 (en) 2006-03-30
CN101001784B (en) 2012-10-17
ATE515446T1 (en) 2011-07-15
MX2007003346A (en) 2007-06-05
PL1799557T3 (en) 2011-11-30
CA2573402C (en) 2012-07-03
HK1105140A1 (en) 2008-02-01

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