EP1758622A1 - Kit zur behandlung von bandscheibendegeneration - Google Patents

Kit zur behandlung von bandscheibendegeneration

Info

Publication number
EP1758622A1
EP1758622A1 EP05773213A EP05773213A EP1758622A1 EP 1758622 A1 EP1758622 A1 EP 1758622A1 EP 05773213 A EP05773213 A EP 05773213A EP 05773213 A EP05773213 A EP 05773213A EP 1758622 A1 EP1758622 A1 EP 1758622A1
Authority
EP
European Patent Office
Prior art keywords
cells
intervertebral disc
connecting piece
vertebrae
assembly according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05773213A
Other languages
English (en)
French (fr)
Inventor
Régis Le Couedic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zimmer Spine SAS
Original Assignee
Zimmer Spine SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zimmer Spine SAS filed Critical Zimmer Spine SAS
Publication of EP1758622A1 publication Critical patent/EP1758622A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
    • A61B17/7035—Screws or hooks, wherein a rod-clamping part and a bone-anchoring part can pivot relative to each other
    • A61B17/7037—Screws or hooks, wherein a rod-clamping part and a bone-anchoring part can pivot relative to each other wherein pivoting is blocked when the rod is clamped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
    • A61B17/7002—Longitudinal elements, e.g. rods
    • A61B17/701—Longitudinal elements with a non-circular, e.g. rectangular, cross-section
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
    • A61B17/7002—Longitudinal elements, e.g. rods
    • A61B17/7011—Longitudinal element being non-straight, e.g. curved, angled or branched
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
    • A61B17/7002—Longitudinal elements, e.g. rods
    • A61B17/7019—Longitudinal elements having flexible parts, or parts connected together, such that after implantation the elements can move relative to each other
    • A61B17/7026—Longitudinal elements having flexible parts, or parts connected together, such that after implantation the elements can move relative to each other with a part that is flexible due to its form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
    • A61B17/7002—Longitudinal elements, e.g. rods
    • A61B17/7019—Longitudinal elements having flexible parts, or parts connected together, such that after implantation the elements can move relative to each other
    • A61B17/7031—Longitudinal elements having flexible parts, or parts connected together, such that after implantation the elements can move relative to each other made wholly or partly of flexible material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84—Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86—Pins or screws or threaded wires; nuts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3852—Cartilage, e.g. meniscus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
    • A61B17/7002—Longitudinal elements, e.g. rods
    • A61B17/7004—Longitudinal elements, e.g. rods with a cross-section which varies along its length
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
    • A61B17/7032—Screws or hooks with U-shaped head or back through which longitudinal rods pass
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7061—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant for stabilising vertebrae or discs by improving the condition of their tissues, e.g. using implanted medication or fluid exchange
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2/4611—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof of spinal prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442—Intervertebral or spinal discs, e.g. resilient
    • A61F2002/444—Intervertebral or spinal discs, e.g. resilient for replacing the nucleus pulposus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442—Intervertebral or spinal discs, e.g. resilient
    • A61F2002/4445—Means for culturing intervertebral disc tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs

Definitions

  • the present invention relates to a set for the treatment of degeneration of an intervertebral disc.
  • the intervertebral disc is a means of joining the vertebral bodies together, the shape of which is that of a biconvex lens which adapts and attaches to the articular surfaces of the bodies of the vertebrae. They are made up of two parts: a very hard peripheral part of very tight texture and a central part which is a soft and gelatinous substance. For various reasons, pathologies of the intervertebral disc can lead to more or less significant degeneration of this disc which then can no longer fulfill its normal function between the vertebrae.
  • the inventors have demonstrated that after the implantation of regeneration cells in the damaged intervertebral disc, the lesion or necrosis of the cells constituting the disc does not disappear or does not disappear sufficiently due to the mechanical pressure exerted on this disc by the vertebrae which surround it. Besides, the inventors have also highlighted that part of the degeneration of the cells of the intervertebral disc could have a purely mechanical origin or that this purely mechanical origin could have created conditions favorable to the degeneration of this disc for other biological lesions.
  • the object of the invention is achieved by a set of treatment for the degeneration of an injured intervertebral disc placed between two vertebrae which is characterized in that it comprises cells analogous or not to those of the intervertebral disc and implantable in said disc; and at least one device for stabilizing the two vertebrae comprising two screws, each screw being intended to be screwed into one of the vertebrae, an elongated connecting piece, and two securing members for securing the head of each of said screws to one of the ends of said connecting piece, whereby excessive mechanical stresses are not applied to the intervertebral disc.
  • the cells implanted in the intervertebral disc will allow the regeneration of the cells of the intervertebral disc and that this regeneration will be possible thanks to the presence of the stabilization device which is screwed into the vertebrae and therefore maintains a spacing between those -this. It thus limits the mechanical stresses applied to the intervertebral disc during treatment.
  • the invention can be used for patients who have undergone partial or total resection of the spinous processes of the vertebrae or whose spinous processes have too poor a bone quality (for example osteoporosis).
  • the intervertebral disc between the fifth lumbar and the sacrum since the first vertebra of the latter generally does not have a spinous process.
  • the invention can therefore be used in cases where interspinous stabilization cannot be carried out for physiological reasons.
  • the implantable cells used can be obtained by various methods such as the removal from an intervertebral disc of the patient, the removal from the bone marrow of the patient of adult stem cells or also by removal of embryonic stem cells.
  • the treatment assembly advantageously comprises means for injecting the cells into the disc, these injection means possibly being of the syringe-cannula type.
  • the connecting piece of the vertebra stabilization device has a certain flexibility.
  • - Figure 1 shows the assembly for treating the degeneration of an intervertebral disc according to the invention
  • - Figure 2A is a sectional view of a first embodiment of the connecting piece of the immobilizer
  • - Figure 2B is a perspective view of the first embodiment immobilizer
  • - Figure 3A is a perspective view of a second embodiment of the connecting piece of the immobilizer
  • - Figure 3B is a perspective view of the embodiment of Figure 3A
  • - Figure 4 is an exploded view of a third embodiment of the immobilization device.
  • FIG 1 there is shown in a simplified manner on the one hand a vertebra stabilization device 10 comprising two screws 12 and 14, a connecting piece 16 and two fixing devices 18 and 20 for immobilizing the connecting piece 16 by compared to screw 12 and 14. Also shown are injectable cells for the regeneration of the intervertebral disc, these cells being symbolically referenced 22 and shown in a culture dish 24. The means for injecting the cells 26 have also been shown.
  • the injection means 26 are constituted in the particular embodiment of the invention represented in this figure by a syringe body 28 and a cannula 30.
  • the device for stabilizing the vertebrae 10 which constitutes a part of the treatment assembly is intended to allow the fixing of a given spacing between the vertebrae surrounding the DI intervertebral disc to be treated and to avoid excessive mechanical stress being applied to this disc.
  • this treatment assembly includes injectable cells for disc therapy, the reflection or implantation of the cells which can take place at the same time as the installation of the stabilization device, or after, as is will explain later.
  • Vertebra stabilization devices are themselves well known for their function of spacing and securing the vertebrae. Such intervertebral immobilization devices are notably described in patent applications FR 02 12397, WO 02/07621 and WO 02/07622.
  • the stabilization device 10 consists essentially of two pedicle screws 12 and 14 which are screwed into the body of the two vertebrae to be secured.
  • Each screw 12 and 14 is equipped with a securing device 18 and 20 for securing the heads of the screws with a connecting piece 16 which thus defines the spacing between the two vertebrae.
  • the connecting piece 16 has a certain flexibility.
  • two stabilization devices are used, each device being mounted on either side of the spinous processes of the vertebrae.
  • implantable cells usable for the regeneration of the intervertebral disc can have different origins: They can be cells taken from the patient at the level of the disc itself and cultured in an adequate medium (possibly in three-dimensional) such as (alginate ball, porous structure in PLA / TGA, collagen foam); It is also possible to use autologous adult stem cells taken from the bone marrow, for example from the iliac crest, then placed in a culture medium identical to those which have been mentioned above. Finally, treated embryonic stem cells can be used in the same manner as previously indicated.
  • These cells can be implanted in the intervertebral disc to be treated at the same time as the placement of the intervertebral implant or else be the subject of a fully-fledged operation taking place before or after the placement of the intervertebral implant. In all cases, similar results are obtained.
  • the operational steps are as follows: - with regard to the installation of the patient undergoing the operation, he is placed in the prone position. A position of physiological lumbar lordosis is desirable. - the surgeon proceeds to expose the two vertebrae adjacent to the disc to be treated.
  • each screw head is intended to receive the end cylindrical 36, 38 of the connecting piece 16.
  • the ends 36 and 38 of the connecting piece are immobilized with respect to the screws by means of clamping screws 40 and 42 which cooperate with a thread formed in the recesses 34 of the heads screws 32.
  • the central part 44 of the connecting piece 16 is made of a material having a certain elasticity to allow limited movement between the vertebrae. This possibility improves patient comfort.
  • the relative movement of the two vertebrae is limited, which avoids the application of excessive mechanical stresses to the intervertebral disc.
  • WO 02/076221 This device differs from that which has been described in connection with FIGS. 2A and 2B only by the embodiment of the central part of the connecting piece which is referenced 16 '.
  • the central part 46 of the connecting piece is constituted by two parallel arms 48 and 50 which are connected at their ends to the cylindrical end portions 36 and 38 of the connecting piece.
  • the central part 46 has at its center a recess 50 which gives this central part a certain deformability while giving the same mechanical resistance as the end portions 36 and 38.
  • FIG. 4 we will describe a third embodiment of the vertebra stabilization device which is described in more detail in French patent application No.
  • each pedicle screw referenced 12 'in the figures comprises a threaded body 60 and a spherical fixing head 62.
  • the connecting piece which is referenced 16 "has the form of an elongated piece having a substantially planar upper face 64 and a lower face 66 also substantially planar.
  • the fixing device which bears the reference 18 ' is first constituted by a ring-shaped part 68.
  • the upper part of the ring 68 is pierced with an orifice 70 which opens into the axial passage 72 of the ring.
  • the orifice 70 is tapped to cooperate with a fixing screw 74.
  • the ring also has in its lower part a recess 76 which comprises an insertion part 78 authorizing the passage of the spherical head 62 of the screw 12 'and a retaining portion 80 which can cooperate with the lower part of the spherical head 62 of the screw to maintain the latter in the space passage 72 of the ring 68.
  • the fastening device 18 ′ finally comprises an intermediate part 82 whose upper face 84 is planar and whose lower face 86 defines a spherical cap capable of cooperating with the upper part of the spherical head 62 of the screw 12 .
  • the fixing piece 68 is engaged on the spherical head 62 of the screw by its insertion housing 78 and then it has been pivoted about its axis. to bring the head of the screw the spherical head 62 of the screw above the retaining recess 80.
  • the intermediate piece 82 and the end of the connecting piece 16 are then placed in the axial passage 72 By screwing the screw 74 including the threaded orifice 70 of the ring, the tightening and therefore the immobilization of the connecting piece 16 "is obtained with respect to the spherical head 62 of the pedicle screws 12 '.

Landscapes

  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Prostheses (AREA)
  • Surgical Instruments (AREA)
  • Materials For Medical Uses (AREA)
EP05773213A 2004-05-25 2005-05-24 Kit zur behandlung von bandscheibendegeneration Withdrawn EP1758622A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0405611A FR2870718B1 (fr) 2004-05-25 2004-05-25 Ensemble de traitement de la degenerescence d'un disque intervertebral
PCT/FR2005/001280 WO2005118015A1 (fr) 2004-05-25 2005-05-24 Ensemble de traitement de la degenerescence d'un disque intervertebral

Publications (1)

Publication Number Publication Date
EP1758622A1 true EP1758622A1 (de) 2007-03-07

Family

ID=34947858

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05773213A Withdrawn EP1758622A1 (de) 2004-05-25 2005-05-24 Kit zur behandlung von bandscheibendegeneration

Country Status (8)

Country Link
US (1) US20080039943A1 (de)
EP (1) EP1758622A1 (de)
JP (1) JP2008500084A (de)
KR (1) KR20070034479A (de)
AU (1) AU2005249740B2 (de)
FR (1) FR2870718B1 (de)
WO (1) WO2005118015A1 (de)
ZA (1) ZA200609826B (de)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2812185B1 (fr) * 2000-07-25 2003-02-28 Spine Next Sa Piece de liaison semi-rigide pour la stabilisation du rachis
FR2812186B1 (fr) * 2000-07-25 2003-02-28 Spine Next Sa Piece de liaison souple pour la stabilisation du rachis
FR2842724B1 (fr) 2002-07-23 2005-05-27 Spine Next Sa Systeme de fixation vertebrale
US7744651B2 (en) 2002-09-18 2010-06-29 Warsaw Orthopedic, Inc Compositions and methods for treating intervertebral discs with collagen-based materials
US20040054414A1 (en) 2002-09-18 2004-03-18 Trieu Hai H. Collagen-based materials and methods for augmenting intervertebral discs
JP2006515765A (ja) 2002-11-15 2006-06-08 エスディージーアイ・ホールディングス・インコーポレーテッド 滑膜性関節を治療するためのコラーゲンベース材料および方法
FR2890850B1 (fr) 2005-09-20 2009-04-17 Abbott Spine Sa Systeme de fixation vertebrale
FR2890851B1 (fr) 2005-09-21 2008-06-20 Abbott Spine Sa Ancillaire de mise en tension d'un lien souple.
US7682376B2 (en) * 2006-01-27 2010-03-23 Warsaw Orthopedic, Inc. Interspinous devices and methods of use
US7578849B2 (en) * 2006-01-27 2009-08-25 Warsaw Orthopedic, Inc. Intervertebral implants and methods of use
US7815663B2 (en) * 2006-01-27 2010-10-19 Warsaw Orthopedic, Inc. Vertebral rods and methods of use
US20070213822A1 (en) * 2006-02-14 2007-09-13 Sdgi Holdings, Inc. Treatment of the vertebral column
US7666211B2 (en) * 2006-12-28 2010-02-23 Mi4Spine, Llc Vertebral disc annular fibrosis tensioning and lengthening device
US8399619B2 (en) 2006-06-30 2013-03-19 Warsaw Orthopedic, Inc. Injectable collagen material
US8118779B2 (en) 2006-06-30 2012-02-21 Warsaw Orthopedic, Inc. Collagen delivery device
EP2047813A1 (de) * 2007-10-11 2009-04-15 Abbott Spine Knochenbefestigungssystem und Verfahren zu dessen Verwendung
US20090143863A1 (en) * 2006-09-22 2009-06-04 Mi4Spine, Llc Method for disc regeneration using stem cell derived chondroprogenitors
US20080312694A1 (en) * 2007-06-15 2008-12-18 Peterman Marc M Dynamic stabilization rod for spinal implants and methods for manufacturing the same
US20090093843A1 (en) * 2007-10-05 2009-04-09 Lemoine Jeremy J Dynamic spine stabilization system
US8128635B2 (en) 2007-10-23 2012-03-06 Zimmer Spine S.A.S. Bone fixation tensioning tool and method
ATE536824T1 (de) 2007-10-23 2011-12-15 Zimmer Spine Befestigungsvorrichtungen und stabilisierungssysteme mit diesen befestigungsvorrichtungen
US8888850B2 (en) * 2007-11-19 2014-11-18 Linares Medical Devices, Llc Combination spacer insert and support for providing inter-cervical vertebral support
US8758439B2 (en) 2007-11-19 2014-06-24 Linares Medical Devices, Llc Spine support implant including inter vertebral insertable fluid ballastable insert and inter-vertebral web retaining harnesses
US8403908B2 (en) 2007-12-17 2013-03-26 Hospira, Inc. Differential pressure based flow sensor assembly for medication delivery monitoring and method of using the same
US8517990B2 (en) 2007-12-18 2013-08-27 Hospira, Inc. User interface improvements for medical devices
ATE515239T1 (de) 2008-04-24 2011-07-15 Zimmer Spine System zur stabilisierung von mindestens einem abschnitt der wirbelsäule
ATE534339T1 (de) 2008-05-20 2011-12-15 Zimmer Spine System zur stabilisierung von mindestens drei wirbeln
US8065924B2 (en) 2008-05-23 2011-11-29 Hospira, Inc. Cassette for differential pressure based medication delivery flow sensor assembly for medication delivery monitoring and method of making the same
US7819838B2 (en) 2008-09-02 2010-10-26 Hospira, Inc. Cassette for use in a medication delivery flow sensor assembly and method of making the same
US20100094344A1 (en) * 2008-10-14 2010-04-15 Kyphon Sarl Pedicle-Based Posterior Stabilization Members and Methods of Use
US20100114165A1 (en) * 2008-11-04 2010-05-06 Abbott Spine, Inc. Posterior dynamic stabilization system with pivoting collars
US20100160968A1 (en) * 2008-12-19 2010-06-24 Abbott Spine Inc. Systems and methods for pedicle screw-based spine stabilization using flexible bands
US8048022B2 (en) 2009-01-30 2011-11-01 Hospira, Inc. Cassette for differential pressure based medication delivery flow sensor assembly for medication delivery monitoring and method of making the same
US8118840B2 (en) 2009-02-27 2012-02-21 Warsaw Orthopedic, Inc. Vertebral rod and related method of manufacture
US9622792B2 (en) 2009-04-29 2017-04-18 Nuvasive Specialized Orthopedics, Inc. Interspinous process device and method
US9011494B2 (en) * 2009-09-24 2015-04-21 Warsaw Orthopedic, Inc. Composite vertebral rod system and methods of use
WO2013028497A1 (en) 2011-08-19 2013-02-28 Hospira, Inc. Systems and methods for a graphical interface including a graphical representation of medical data
US10022498B2 (en) 2011-12-16 2018-07-17 Icu Medical, Inc. System for monitoring and delivering medication to a patient and method of using the same to minimize the risks associated with automated therapy
JP6306566B2 (ja) 2012-03-30 2018-04-04 アイシーユー・メディカル・インコーポレーテッド 注入システムのポンプ内の空気を検出するための空気検出システムおよび方法
ES2743160T3 (es) 2012-07-31 2020-02-18 Icu Medical Inc Sistema de cuidado de pacientes para medicaciones críticas
US10046112B2 (en) 2013-05-24 2018-08-14 Icu Medical, Inc. Multi-sensor infusion system for detecting air or an occlusion in the infusion system
WO2014194065A1 (en) 2013-05-29 2014-12-04 Hospira, Inc. Infusion system and method of use which prevents over-saturation of an analog-to-digital converter
ES2838450T3 (es) 2013-05-29 2021-07-02 Icu Medical Inc Sistema de infusión que utiliza uno o más sensores e información adicional para hacer una determinación de aire en relación con el sistema de infusión
US20150133861A1 (en) 2013-11-11 2015-05-14 Kevin P. McLennan Thermal management system and method for medical devices
AU2015222800B2 (en) 2014-02-28 2019-10-17 Icu Medical, Inc. Infusion system and method which utilizes dual wavelength optical air-in-line detection
WO2015184366A1 (en) 2014-05-29 2015-12-03 Hospira, Inc. Infusion system and pump with configurable closed loop delivery rate catch-up
US10143795B2 (en) 2014-08-18 2018-12-04 Icu Medical, Inc. Intravenous pole integrated power, control, and communication system and method for an infusion pump
US11344668B2 (en) 2014-12-19 2022-05-31 Icu Medical, Inc. Infusion system with concurrent TPN/insulin infusion
US10850024B2 (en) 2015-03-02 2020-12-01 Icu Medical, Inc. Infusion system, device, and method having advanced infusion features
ES2809505T3 (es) 2015-05-26 2021-03-04 Icu Medical Inc Dispositivo de administración de fluido de infusión desechable para la administración programable de fármacos de gran volumen
EP3454922B1 (de) 2016-05-13 2022-04-06 ICU Medical, Inc. Infusionspumpensystem mit gemeinsamer leitung zur automatischen spülung
EP3468635B1 (de) 2016-06-10 2024-09-25 ICU Medical, Inc. Akustischer durchflusssensor für kontinuierliche medikamentenflussmessungen und feedback-steuerung von infusionen
US10089055B1 (en) 2017-12-27 2018-10-02 Icu Medical, Inc. Synchronized display of screen content on networked devices
USD939079S1 (en) 2019-08-22 2021-12-21 Icu Medical, Inc. Infusion pump
US11278671B2 (en) 2019-12-04 2022-03-22 Icu Medical, Inc. Infusion pump with safety sequence keypad
AU2021311443A1 (en) 2020-07-21 2023-03-09 Icu Medical, Inc. Fluid transfer devices and methods of use
US11135360B1 (en) 2020-12-07 2021-10-05 Icu Medical, Inc. Concurrent infusion with common line auto flush

Family Cites Families (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2585207A (en) * 1950-10-11 1952-02-12 John A Zublin Apparatus for drilling lateral bores deviating from vertical well bores
AU578687B2 (en) * 1984-03-30 1988-11-03 Osteonics Biomaterials, Inc. Orthopedic device and method for making the same
US4743260A (en) * 1985-06-10 1988-05-10 Burton Charles V Method for a flexible stabilization system for a vertebral column
US4648388B1 (en) * 1985-11-01 1995-10-31 Acromed Corp Apparatus and method for maintaining vertebrae in a desired relationship
US4805602A (en) * 1986-11-03 1989-02-21 Danninger Medical Technology Transpedicular screw and rod system
SE466732B (sv) * 1987-10-29 1992-03-30 Atos Medical Ab Ledprotes, innefattande en ledkropp mellan ett par tappar foer infaestning i ben
DE8807485U1 (de) * 1988-06-06 1989-08-10 Mecron Medizinische Produkte Gmbh, 1000 Berlin Endoprothese der Zwischenwirbelscheibe
US4917700A (en) * 1988-08-01 1990-04-17 Zimmer, Inc. Prosthetic ligament
FR2642645B1 (fr) * 1989-02-03 1992-08-14 Breard Francis Stabilisateur intervertebral souple ainsi que procede et appareillage pour le controle de sa tension avant mise en place sur le rachis
EP0447355A1 (de) * 1990-03-12 1991-09-18 Gebrüder Sulzer Aktiengesellschaft Implantat für den menschlichen Körper
US5102412A (en) * 1990-06-19 1992-04-07 Chaim Rogozinski System for instrumentation of the spine in the treatment of spinal deformities
DE4129188A1 (de) * 1991-09-03 1993-03-04 Spinnstoffabrik Zehlendorf Ag Schmelzfaserverklebter schichtstoff, verfahren und zwischenprodukt zu dessen herstellung und dessen verwendung
FR2693364B1 (fr) * 1992-07-07 1995-06-30 Erpios Snc Prothese intervertebrale permettant une stabilisation des contraintes rotatoires et de flexion-extension.
GB9217578D0 (en) * 1992-08-19 1992-09-30 Surgicarft Ltd Surgical implants,etc
FR2697743B1 (fr) * 1992-11-09 1995-01-27 Fabrication Mat Orthopedique S Dispositif d'ostéosynthèse rachidienne applicable notamment aux vertèbres dégénératives.
US5496318A (en) * 1993-01-08 1996-03-05 Advanced Spine Fixation Systems, Inc. Interspinous segmental spine fixation device
FR2701650B1 (fr) * 1993-02-17 1995-05-24 Psi Amortisseur double pour la stabilisation intervertébrale.
US5601554A (en) * 1993-03-04 1997-02-11 Advanced Spine Fixation Systems, Inc. Branch connector for spinal fixation systems
FR2709247B1 (fr) * 1993-08-27 1995-09-29 Martin Jean Raymond Dispositif d'ancrage d'une instrumentation rachidienne sur une vertèbre.
US5611800A (en) * 1994-02-15 1997-03-18 Alphatec Manufacturing, Inc. Spinal fixation system
US5616142A (en) * 1994-07-20 1997-04-01 Yuan; Hansen A. Vertebral auxiliary fixation device
US5488761A (en) * 1994-07-28 1996-02-06 Leone; Ronald P. Flexible shaft and method for manufacturing same
AU6499596A (en) * 1995-07-18 1997-02-18 Edwards, Garland U. Flexible shaft
JPH09215753A (ja) * 1996-02-08 1997-08-19 Schneider Usa Inc チタン合金製自己拡張型ステント
US6695842B2 (en) * 1997-10-27 2004-02-24 St. Francis Medical Technologies, Inc. Interspinous process distraction system and method with positionable wing and method
DE29711559U1 (de) * 1997-07-02 1997-08-21 Howmedica GmbH, 24232 Schönkirchen Längliches Element zur Übertragung von Kräften
US6206882B1 (en) * 1999-03-30 2001-03-27 Surgical Dynamics Inc. Plating system for the spine
US6419702B1 (en) * 1999-08-13 2002-07-16 Bret A. Ferree Treating degenerative disc disease through transplantation of the nucleus pulposis
US6352557B1 (en) * 1999-08-13 2002-03-05 Bret A. Ferree Treating degenerative disc disease through transplantion of extracellular nucleus pulposus matrix and autograft nucleus pulposus cells
US6723335B1 (en) * 2000-04-07 2004-04-20 Jeffrey William Moehlenbruck Methods and compositions for treating intervertebral disc degeneration
WO2002000126A1 (en) * 2000-06-23 2002-01-03 University Of Southern California Percutaneous vertebral fusion system
US6964667B2 (en) * 2000-06-23 2005-11-15 Sdgi Holdings, Inc. Formed in place fixation system with thermal acceleration
US6875212B2 (en) * 2000-06-23 2005-04-05 Vertelink Corporation Curable media for implantable medical device
US6551321B1 (en) * 2000-06-23 2003-04-22 Centerpulse Orthopedics Inc. Flexible intramedullary nail
FR2812186B1 (fr) * 2000-07-25 2003-02-28 Spine Next Sa Piece de liaison souple pour la stabilisation du rachis
FR2812185B1 (fr) * 2000-07-25 2003-02-28 Spine Next Sa Piece de liaison semi-rigide pour la stabilisation du rachis
US6554831B1 (en) * 2000-09-01 2003-04-29 Hopital Sainte-Justine Mobile dynamic system for treating spinal disorder
ATE296580T1 (de) * 2000-09-18 2005-06-15 Zimmer Gmbh Pedikelschraube für intervertebrale stützelemente
US6652585B2 (en) * 2001-02-28 2003-11-25 Sdgi Holdings, Inc. Flexible spine stabilization system
US20030069639A1 (en) * 2001-04-14 2003-04-10 Tom Sander Methods and compositions for repair or replacement of joints and soft tissues
AU2002250593A1 (en) * 2001-04-19 2002-11-05 Spineology, Inc. Stacked intermedular rods for spinal fixation
US6783527B2 (en) * 2001-10-30 2004-08-31 Sdgi Holdings, Inc. Flexible spinal stabilization system and method
HU223787B1 (hu) * 2001-10-31 2005-01-28 Gyula Subotics Készülék, főleg vércukorszint non-invazív mérésére
US6679883B2 (en) * 2001-10-31 2004-01-20 Ortho Development Corporation Cervical plate for stabilizing the human spine
EP1450707B1 (de) * 2001-12-07 2007-09-26 Synthes GmbH Dämpfungselement für die Wirbelsäule
US6966910B2 (en) * 2002-04-05 2005-11-22 Stephen Ritland Dynamic fixation device and method of use
CA2484923C (en) * 2002-05-08 2011-02-22 Stephen Ritland Dynamic fixation device and method of use
US20040015166A1 (en) * 2002-07-22 2004-01-22 Gorek Josef E. System and method for stabilizing the spine by securing spine stabilization rods in crossed disposition
US7029495B2 (en) * 2002-08-28 2006-04-18 Scimed Life Systems, Inc. Medical devices and methods of making the same
US7066938B2 (en) * 2002-09-09 2006-06-27 Depuy Spine, Inc. Snap-on spinal rod connector
WO2004024037A1 (en) * 2002-09-10 2004-03-25 Ferree Bret A Shock-absorbing joint and spine replacements
FR2845587B1 (fr) * 2002-10-14 2005-01-21 Scient X Dispositif dynamique de liaison intervertebrale a debattement controle multidirectionnel
US20050075634A1 (en) * 2002-10-29 2005-04-07 Zucherman James F. Interspinous process implant with radiolucent spacer and lead-in tissue expander
US7549999B2 (en) * 2003-05-22 2009-06-23 Kyphon Sarl Interspinous process distraction implant and method of implantation
EP2366349B1 (de) * 2002-10-30 2017-04-05 Zimmer Spine, Inc. Spinaler Stabilisierungssystemeinsatz
JP4598760B2 (ja) * 2003-02-25 2010-12-15 リットランド、ステファン 調整ロッド及びコネクタ機器、並びにその使用方法
US20070016200A1 (en) * 2003-04-09 2007-01-18 Jackson Roger P Dynamic stabilization medical implant assemblies and methods
ES2258678T3 (es) * 2003-04-24 2006-09-01 Zimmer Gmbh Sistema instrumental para tornillos pediculares.
KR20080057332A (ko) * 2003-05-02 2008-06-24 예일 유니버시티 동적 척추 안정장치
US6986771B2 (en) * 2003-05-23 2006-01-17 Globus Medical, Inc. Spine stabilization system
EP1628563B1 (de) * 2003-05-23 2009-09-23 Globus Medical, Inc. Wirbelsäulenstabilisationssystem
US7766915B2 (en) * 2004-02-27 2010-08-03 Jackson Roger P Dynamic fixation assemblies with inner core and outer coil-like member
US20050203513A1 (en) * 2003-09-24 2005-09-15 Tae-Ahn Jahng Spinal stabilization device
US7137985B2 (en) * 2003-09-24 2006-11-21 N Spine, Inc. Marking and guidance method and system for flexible fixation of a spine
DE10348329B3 (de) * 2003-10-17 2005-02-17 Biedermann Motech Gmbh Stabförmiges Element für die Anwendung in der Wirbelsäulen- oder Unfallchirurgie,Stabilisierungseinrichtung mit einem solchen stabförmigen Element und Herstellungsverfahren für das stabförmige Element
US7588575B2 (en) * 2003-10-21 2009-09-15 Innovative Spinal Technologies Extension for use with stabilization systems for internal structures
US7175626B2 (en) * 2004-06-15 2007-02-13 Board Of Regents Of The University Of Nebraska Dynamic compression device and driving tool
US7955357B2 (en) * 2004-07-02 2011-06-07 Ellipse Technologies, Inc. Expandable rod system to treat scoliosis and method of using the same
US20060009845A1 (en) * 2004-07-08 2006-01-12 Chin Kingsley R Method and device for kinematic retaining cervical plating
US7611526B2 (en) * 2004-08-03 2009-11-03 K Spine, Inc. Spinous process reinforcement device and method
US7854752B2 (en) * 2004-08-09 2010-12-21 Theken Spine, Llc System and method for dynamic skeletal stabilization
US7887566B2 (en) * 2004-09-16 2011-02-15 Hynes Richard A Intervertebral support device with bias adjustment and related methods
BRPI0419057A (pt) * 2004-09-22 2007-12-11 Kyung-Woo Park aparelho de fixação espinhal
US8162985B2 (en) * 2004-10-20 2012-04-24 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
EP1719468A1 (de) * 2004-12-17 2006-11-08 Zimmer GmbH Intervertebrales Stabilisierungssystem
US20070088359A1 (en) * 2005-02-07 2007-04-19 Woods Richard W Universal dynamic spine stabilization device and method of use
US7828825B2 (en) * 2005-06-20 2010-11-09 Warsaw Orthopedic, Inc. Multi-level multi-functional spinal stabilization systems and methods
US7799060B2 (en) * 2005-06-20 2010-09-21 Warsaw Orthopedic, Inc. Multi-directional spinal stabilization systems and methods
US20070016190A1 (en) * 2005-07-14 2007-01-18 Medical Device Concepts Llc Dynamic spinal stabilization system
US20070016204A1 (en) * 2005-07-14 2007-01-18 Medical Device Concepts Llc. Spinal buttress device and method
DE602005007223D1 (de) * 2005-08-24 2008-07-10 Biedermann Motech Gmbh Stabförmiges Element für die Anwendung in der Wirbelsäulen- oder Unfallchirurgie und Stabilisierungseinrichtung mit einem solchen Element
WO2007025236A2 (en) * 2005-08-26 2007-03-01 Innovative Spinal Technologies Alignment instrument for dynamic spinal stabilization systems
US8226689B2 (en) * 2005-09-23 2012-07-24 Zimmer Spine, Inc. Apparatus and methods for spinal implant with variable link mechanism
US7879074B2 (en) * 2005-09-27 2011-02-01 Depuy Spine, Inc. Posterior dynamic stabilization systems and methods
US20070093813A1 (en) * 2005-10-11 2007-04-26 Callahan Ronald Ii Dynamic spinal stabilizer
US20080009863A1 (en) * 2006-06-23 2008-01-10 Zimmer Spine, Inc. Pedicle screw distractor and associated method of use
US7927356B2 (en) * 2006-07-07 2011-04-19 Warsaw Orthopedic, Inc. Dynamic constructs for spinal stabilization
US20080021465A1 (en) * 2006-07-20 2008-01-24 Shadduck John H Spine treatment devices and methods
US20080065073A1 (en) * 2006-09-08 2008-03-13 Michael Perriello Offset dynamic motion spinal stabilization system

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2005118015A1 *

Also Published As

Publication number Publication date
FR2870718A1 (fr) 2005-12-02
AU2005249740B2 (en) 2011-01-20
WO2005118015A1 (fr) 2005-12-15
AU2005249740A1 (en) 2005-12-15
US20080039943A1 (en) 2008-02-14
KR20070034479A (ko) 2007-03-28
FR2870718B1 (fr) 2006-09-22
ZA200609826B (en) 2008-06-25
JP2008500084A (ja) 2008-01-10

Similar Documents

Publication Publication Date Title
WO2005118015A1 (fr) Ensemble de traitement de la degenerescence d'un disque intervertebral
EP1585448B1 (de) System zur behandlung der degeneration einer bandscheibe
EP1753353B1 (de) Bandscheibenimplantatsystem
EP0807420B1 (de) Knochenbefestigungsvorrichtung, insbesondere des Kreuzbeines, für die Osteosynthese der Wirbelsäule
FR2887434A1 (fr) Materiel de traitement chirurgical de deux vertebres
FR2805457A1 (fr) Implant intervertebral a corps et face d'appui
EP1414358A2 (de) Anordnung zur stabilisierung des rückgrates
EP1795136A1 (de) Einrichtung zur dynamischen Stabilisierung von Wirbeln
WO2007077319A2 (fr) Espaceur discal anatomique et ses applications
FR2884135A1 (fr) Implant intervertebral pour l'articulation lombo-sacree
FR2908035A1 (fr) Implant interepineux
FR2959928A1 (fr) Systeme de retention d'un organe d'ancrage sur une piece implantable
FR2971139A1 (fr) Plaque pour l'osteosynthese de l'articulation lombo-sacree
FR2989264A1 (fr) Materiel d'osteosynthese vertebrale
FR2978343A1 (fr) Organe d'ancrage pour materiel d'osteosynthese vertebrale
EP1795135B1 (de) Einrichtung zur lateralen dynamischen Stabilisierung der Wirbelsäule
FR2894127A1 (fr) Dispositif de stabilisation laterale du rachis
WO2009092907A2 (fr) Prothese de disques intervertebraux
FR2892616A1 (fr) Implant chirurgical intervertebral comprenant un element viscoelastique
EP2398423A1 (de) Bandscheibenprothese
FR2798059A1 (fr) Implant intersomatique, dispositif pour la stabilisation du rachis et kit pour la realisation d'une arthrodese
EP2136743A1 (de) Bandscheibenimplantat für menschlichen körper oder tierkörper
FR2929829A1 (fr) Systeme de liaison entre un implant remplacant un corps vertebral et une instrumentation de fixation
WO2008043906A2 (fr) Ensemble de stabilisation intervertebrale
FR2978347A1 (fr) Materiel d'osteosynthese vertebrale

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20061124

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): DE ES FR GB IT

DAX Request for extension of the european patent (deleted)
RBV Designated contracting states (corrected)

Designated state(s): DE ES FR GB IT

17Q First examination report despatched

Effective date: 20090506

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: ZIMMER SPINE

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20110720