EP1706080A2 - Epithelbehandlungsverfahren und vorrichtungen zur behandlung des epithels - Google Patents

Epithelbehandlungsverfahren und vorrichtungen zur behandlung des epithels

Info

Publication number
EP1706080A2
EP1706080A2 EP04811056A EP04811056A EP1706080A2 EP 1706080 A2 EP1706080 A2 EP 1706080A2 EP 04811056 A EP04811056 A EP 04811056A EP 04811056 A EP04811056 A EP 04811056A EP 1706080 A2 EP1706080 A2 EP 1706080A2
Authority
EP
European Patent Office
Prior art keywords
eye
epithelium
opening
epithelial
lens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04811056A
Other languages
English (en)
French (fr)
Inventor
Edward Perez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tissue Engineering Refraction Inc
Original Assignee
Tissue Engineering Refraction Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tissue Engineering Refraction Inc filed Critical Tissue Engineering Refraction Inc
Publication of EP1706080A2 publication Critical patent/EP1706080A2/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/013—Instruments for compensation of ocular refraction ; Instruments for use in cornea removal, for reshaping or performing incisions in the cornea
    • A61F9/0133—Knives or scalpels specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00861—Methods or devices for eye surgery using laser adapted for treatment at a particular location
    • A61F2009/00872—Cornea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts

Definitions

  • Another treatment regime is the introduction of an IL-1 receptor agonist, or a FAS receptor agonist beneath the corneal epithelium prior, during, or after the delaminating procedure.
  • an IL-1 receptor agonist or a FAS receptor agonist
  • IL-1 receptor agonist or a FAS receptor agonist
  • IL-1 alpha and IL-1 beta are released from the corneal epithelial cells, upon injury, which may stimulate apoptosis.
  • bandage contact lenses are sometimes used to aid the healing process.
  • bandage contact lenses are sometimes used to aid the healing process.
  • suitable modifications to traditional bandage contact e.g., those made of silicone based hydrogels and other accepted polymeric materials
  • My bandage contact lenses are shown in Figures 5C and 5D.
  • a bandage contact lens (500) is placed on top of an epithelial layer (502).
  • the bandage contact lens (500) may not be constructed of the same material as traditional soft contact lenses, which are often employed as bandages.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Surgery (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP04811056A 2003-11-14 2004-11-15 Epithelbehandlungsverfahren und vorrichtungen zur behandlung des epithels Withdrawn EP1706080A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51990303P 2003-11-14 2003-11-14
PCT/US2004/038186 WO2005049071A2 (en) 2003-11-14 2004-11-15 Epithelium treatment methods and devices for treating the epithelium

Publications (1)

Publication Number Publication Date
EP1706080A2 true EP1706080A2 (de) 2006-10-04

Family

ID=34619393

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04811056A Withdrawn EP1706080A2 (de) 2003-11-14 2004-11-15 Epithelbehandlungsverfahren und vorrichtungen zur behandlung des epithels

Country Status (10)

Country Link
EP (1) EP1706080A2 (de)
JP (1) JP2007511293A (de)
KR (1) KR20060126971A (de)
CN (1) CN1905847A (de)
AU (1) AU2004291138A1 (de)
BR (1) BRPI0416037A (de)
CA (1) CA2545885A1 (de)
IL (1) IL175579A0 (de)
MX (1) MXPA06005434A (de)
WO (1) WO2005049071A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004024035A1 (en) 2002-09-13 2004-03-25 Ocular Sciences, Inc. Devices and methods for improving vision
WO2007123644A2 (en) * 2006-03-28 2007-11-01 Tissue Engineering Refraction, Inc. Partially lubricious epithelial delaminator
US7883520B2 (en) 2006-04-10 2011-02-08 Forsight Labs, Llc Corneal epithelial pocket formation systems, components and methods
GB0620537D0 (en) * 2006-10-17 2006-11-22 Univ Southampton Copolymers suitable for use in corneal bandages
WO2009022339A1 (en) * 2007-08-15 2009-02-19 Ramot At Tel Aviv University Ltd. Polypeptides, matrices, hydrogels and methods of using same for tissue regeneration and repair
EP3442481B1 (de) 2016-04-13 2023-06-28 Avedro, Inc. Systeme zur abgabe von arzneimitteln an ein auge

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2127879A1 (en) * 1992-11-20 1994-05-21 Shinseiro Okamoto Method and apparatus for operation on eye cornea
IT1325891B (it) * 2001-06-22 2004-12-30 Abb Service Srl Polo interruttore miniaturizzato
MXPA04006954A (es) * 2002-01-17 2005-03-23 Perez Edward Metodos para producir colgajos epiteliales sobre la cornea y para la colocacion de dispositivos oculares y lentes debajo de un colgajo o membrana epitelial, dispositivo de deslaminacion epitelial, y estructuras de epitelio y dispositivos y lentes ocu

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2005049071A2 *

Also Published As

Publication number Publication date
CN1905847A (zh) 2007-01-31
KR20060126971A (ko) 2006-12-11
JP2007511293A (ja) 2007-05-10
WO2005049071A2 (en) 2005-06-02
WO2005049071A3 (en) 2005-11-17
MXPA06005434A (es) 2007-01-25
CA2545885A1 (en) 2005-06-02
IL175579A0 (en) 2006-09-05
AU2004291138A1 (en) 2005-06-02
BRPI0416037A (pt) 2007-01-02

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LU MC NL PL PT RO SE SI SK TR

RIN1 Information on inventor provided before grant (corrected)

Inventor name: PEREZ, EDWARD

DAX Request for extension of the european patent (deleted)
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Effective date: 20080603