EP1631597A4 - Chemische festphasenligation mit austauschbarem linker - Google Patents

Chemische festphasenligation mit austauschbarem linker

Info

Publication number
EP1631597A4
EP1631597A4 EP04752449A EP04752449A EP1631597A4 EP 1631597 A4 EP1631597 A4 EP 1631597A4 EP 04752449 A EP04752449 A EP 04752449A EP 04752449 A EP04752449 A EP 04752449A EP 1631597 A4 EP1631597 A4 EP 1631597A4
Authority
EP
European Patent Office
Prior art keywords
solid phase
chemical ligation
phase chemical
linker solid
displaceable linker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04752449A
Other languages
English (en)
French (fr)
Other versions
EP1631597A2 (de
Inventor
Donald Low
Ying Hu
Paolo Botti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gryphon Therapeutics Inc
Original Assignee
Gryphon Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gryphon Therapeutics Inc filed Critical Gryphon Therapeutics Inc
Publication of EP1631597A2 publication Critical patent/EP1631597A2/de
Publication of EP1631597A4 publication Critical patent/EP1631597A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
EP04752449A 2003-05-22 2004-05-17 Chemische festphasenligation mit austauschbarem linker Withdrawn EP1631597A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47329403P 2003-05-22 2003-05-22
PCT/US2004/015435 WO2004105685A2 (en) 2003-05-22 2004-05-17 Displaceable linker solid phase chemical ligation

Publications (2)

Publication Number Publication Date
EP1631597A2 EP1631597A2 (de) 2006-03-08
EP1631597A4 true EP1631597A4 (de) 2007-07-11

Family

ID=33490583

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04752449A Withdrawn EP1631597A4 (de) 2003-05-22 2004-05-17 Chemische festphasenligation mit austauschbarem linker

Country Status (2)

Country Link
EP (1) EP1631597A4 (de)
WO (1) WO2004105685A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040248162A1 (en) * 2002-12-17 2004-12-09 Affymetrix, Inc. Releasable polymer arrays
US7547775B2 (en) 2004-12-31 2009-06-16 Affymetrix, Inc. Parallel preparation of high fidelity probes in an array format
GB0505200D0 (en) * 2005-03-14 2005-04-20 Univ Southampton Process
EP1871403B1 (de) 2005-03-31 2010-09-08 Amylin Pharmaceuticals, Inc. Zusammensetzungen und verfahren zur kontrolle, prävention und behandlung von essstörungen
ES2389747T3 (es) 2007-02-05 2012-10-31 Amylin Pharmaceuticals, Inc. Péptidos FN-38 para su uso en el tratamiento de desórdenes psicóticos y de ansiedad
US8409526B2 (en) * 2010-12-09 2013-04-02 General Electric Company Cellulose substrates, compositions and methods for storage and analysis of biological materials
MX365465B (es) 2013-03-21 2019-06-04 Sanofi Aventis Deutschland Sintesis de productos peptidicos que contienen imida ciclica.
HUE034308T2 (en) 2013-03-21 2018-02-28 Sanofi Aventis Deutschland Preparation of hydantoin-containing peptide products
KR20160062035A (ko) 2013-09-11 2016-06-01 덴마크스 텍니스케 유니버시테트 히드라지드 및 피라노피라졸의 고체상 합성용 광분해성 링커
KR20210072021A (ko) 2018-10-01 2021-06-16 유니베르시떼 드 제네브 생물학 분석에 적합한 복수의 폴리펩티드 변이체의 생산 방법

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004060925A2 (en) * 2002-12-30 2004-07-22 Gryphon Therapeutics, Inc. Multiplex polymer ligation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE465155B (sv) * 1989-12-19 1991-08-05 Exploaterings Ab Tbf Metallkelatbildande hydrofil polymer foer adsorption etc samt ett saett foer framstaellning av polymeren
DE19626762A1 (de) * 1996-07-03 1998-01-08 Basf Ag Enzymatisch spaltbare Linker für Festphasensynthesen
ATE354584T1 (de) * 1997-06-13 2007-03-15 Gryphon Therapeutics Inc Festphasige native chemische ligation von ungeschützten oder n-cystein-geschützten peptiden in wässrigen lösungen

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004060925A2 (en) * 2002-12-30 2004-07-22 Gryphon Therapeutics, Inc. Multiplex polymer ligation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
K NGU & D V PATEL: "Preparation of acid-labile resins with halide linkers and their utility in solid phase organic synthesis", TETRAHEDRON LETTERS., vol. 38, no. 6, 1997, NL ELSEVIER, AMSTERDAM., pages 973 - 976, XP002918776 *

Also Published As

Publication number Publication date
WO2004105685A3 (en) 2005-06-09
WO2004105685A2 (en) 2004-12-09
EP1631597A2 (de) 2006-03-08

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20051202

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL HR LT LV MK

RIN1 Information on inventor provided before grant (corrected)

Inventor name: BOTTI, PAOLO

Inventor name: HU, YING

Inventor name: LOW, DONALD

A4 Supplementary search report drawn up and despatched

Effective date: 20070613

RIC1 Information provided on ipc code assigned before grant

Ipc: C07K 1/107 20060101ALI20070606BHEP

Ipc: C07K 1/04 20060101ALI20070606BHEP

Ipc: C08B 37/00 20060101ALI20070606BHEP

Ipc: C08F 2/00 20060101AFI20050622BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20070913