EP1631597A4 - Displaceable linker solid phase chemical ligation - Google Patents

Displaceable linker solid phase chemical ligation

Info

Publication number
EP1631597A4
EP1631597A4 EP04752449A EP04752449A EP1631597A4 EP 1631597 A4 EP1631597 A4 EP 1631597A4 EP 04752449 A EP04752449 A EP 04752449A EP 04752449 A EP04752449 A EP 04752449A EP 1631597 A4 EP1631597 A4 EP 1631597A4
Authority
EP
European Patent Office
Prior art keywords
solid phase
chemical ligation
phase chemical
linker solid
displaceable linker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04752449A
Other languages
German (de)
French (fr)
Other versions
EP1631597A2 (en
Inventor
Donald Low
Ying Hu
Paolo Botti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gryphon Therapeutics Inc
Original Assignee
Gryphon Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gryphon Therapeutics Inc filed Critical Gryphon Therapeutics Inc
Publication of EP1631597A2 publication Critical patent/EP1631597A2/en
Publication of EP1631597A4 publication Critical patent/EP1631597A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
EP04752449A 2003-05-22 2004-05-17 Displaceable linker solid phase chemical ligation Withdrawn EP1631597A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47329403P 2003-05-22 2003-05-22
PCT/US2004/015435 WO2004105685A2 (en) 2003-05-22 2004-05-17 Displaceable linker solid phase chemical ligation

Publications (2)

Publication Number Publication Date
EP1631597A2 EP1631597A2 (en) 2006-03-08
EP1631597A4 true EP1631597A4 (en) 2007-07-11

Family

ID=33490583

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04752449A Withdrawn EP1631597A4 (en) 2003-05-22 2004-05-17 Displaceable linker solid phase chemical ligation

Country Status (2)

Country Link
EP (1) EP1631597A4 (en)
WO (1) WO2004105685A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040248162A1 (en) * 2002-12-17 2004-12-09 Affymetrix, Inc. Releasable polymer arrays
US7547775B2 (en) 2004-12-31 2009-06-16 Affymetrix, Inc. Parallel preparation of high fidelity probes in an array format
GB0505200D0 (en) * 2005-03-14 2005-04-20 Univ Southampton Process
KR101383493B1 (en) 2005-03-31 2014-04-11 아스트라제네카 파마수티컬스 엘피 Amylin and amylin agonists for treating psychiatric diseases and disorders
EP2120985B1 (en) 2007-02-05 2012-06-27 Amylin Pharmaceuticals, Inc. FN-38 peptides for use in the treatment of psychotic and anxiety disorders
US8409526B2 (en) * 2010-12-09 2013-04-02 General Electric Company Cellulose substrates, compositions and methods for storage and analysis of biological materials
ES2624961T3 (en) 2013-03-21 2017-07-18 Sanofi-Aventis Deutschland Gmbh Synthesis of peptide products containing cyclic imide
US10087221B2 (en) 2013-03-21 2018-10-02 Sanofi-Aventis Deutschland Gmbh Synthesis of hydantoin containing peptide products
CA2922332A1 (en) 2013-09-11 2015-03-19 Danmarks Tekniske Universitet A photolabile linker for the solid-phase synthesis of hydrazides and pyranopyrazoles
KR20210072021A (en) 2018-10-01 2021-06-16 유니베르시떼 드 제네브 Methods for producing a plurality of polypeptide variants suitable for biological analysis
WO2024146707A1 (en) 2023-01-06 2024-07-11 Université De Genève Variant ligand conjugates for payload delivery

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004060925A2 (en) * 2002-12-30 2004-07-22 Gryphon Therapeutics, Inc. Multiplex polymer ligation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE465155B (en) * 1989-12-19 1991-08-05 Exploaterings Ab Tbf METAL CHELET FORMING HYDROPHIL POLYMER FOR ADSORPTION ETC AND A SAT FOR PREPARATION OF THE POLYMER
DE19626762A1 (en) * 1996-07-03 1998-01-08 Basf Ag Enzymatically cleavable linker for solid phase synthesis
DE69828287T2 (en) * 1997-06-13 2005-12-15 Gryphon Therapeutics, Inc., South San Francisco SOLID PHASE NATIVE CHEMICAL LIGATION OF UNPROTECTED OR N-CYSTEIN PROTECTED PEPTIDES IN AQUEOUS SOLUTIONS

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004060925A2 (en) * 2002-12-30 2004-07-22 Gryphon Therapeutics, Inc. Multiplex polymer ligation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
K NGU & D V PATEL: "Preparation of acid-labile resins with halide linkers and their utility in solid phase organic synthesis", TETRAHEDRON LETTERS., vol. 38, no. 6, 1997, NL ELSEVIER, AMSTERDAM., pages 973 - 976, XP002918776 *

Also Published As

Publication number Publication date
EP1631597A2 (en) 2006-03-08
WO2004105685A3 (en) 2005-06-09
WO2004105685A2 (en) 2004-12-09

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20051202

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL HR LT LV MK

RIN1 Information on inventor provided before grant (corrected)

Inventor name: BOTTI, PAOLO

Inventor name: HU, YING

Inventor name: LOW, DONALD

A4 Supplementary search report drawn up and despatched

Effective date: 20070613

RIC1 Information provided on ipc code assigned before grant

Ipc: C07K 1/107 20060101ALI20070606BHEP

Ipc: C07K 1/04 20060101ALI20070606BHEP

Ipc: C08B 37/00 20060101ALI20070606BHEP

Ipc: C08F 2/00 20060101AFI20050622BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20070913