EP1629822B1 - Device for monitoring the administration of doses - Google Patents

Device for monitoring the administration of doses Download PDF

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Publication number
EP1629822B1
EP1629822B1 EP20050107739 EP05107739A EP1629822B1 EP 1629822 B1 EP1629822 B1 EP 1629822B1 EP 20050107739 EP20050107739 EP 20050107739 EP 05107739 A EP05107739 A EP 05107739A EP 1629822 B1 EP1629822 B1 EP 1629822B1
Authority
EP
European Patent Office
Prior art keywords
monitoring device
container unit
dose
administration
medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Not-in-force
Application number
EP20050107739
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1629822A3 (en
EP1629822A2 (en
Inventor
Kari Korander
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dose Control Oy
Original Assignee
Dose Control Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dose Control Oy filed Critical Dose Control Oy
Publication of EP1629822A2 publication Critical patent/EP1629822A2/en
Publication of EP1629822A3 publication Critical patent/EP1629822A3/en
Application granted granted Critical
Publication of EP1629822B1 publication Critical patent/EP1629822B1/en
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0481—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers working on a schedule basis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0418—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with electronic history memory
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0427—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0427—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system
    • A61J7/0436—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system resulting from removing a drug from, or opening, a container

Definitions

  • the invention relates to a device for monitoring the administration of doses, defined in more detail in the preamble of the independent claim.
  • patent US-5200891 discloses a container unit of orally administered doses of medicine, intended for home use, comprising spaces for storing each drug and also including a reminder function to alarm of the time when each dose of medicine is to be administered.
  • the container unit also detects if the dose of medicine has been administered appropriately from the space corresponding to the time of administration.
  • the storage spaces in the container unit are arranged as a set of compartments in the box-like frame of the container unit, wherein each compartment in turn can be pulled out, like a drawer, for the administration of a dose of medicine.
  • container units so-called “dosette” boxes, which are equipped with an openable and closable set of compartments that is arrayed in a matrix form (generally n ⁇ m matrix, n being the number of rows and m the number of columns, and n being equal to or different from m), wherein each compartment in the set of compartments can be separately opened for administering a dose of medicine according to instructions in connection with the container unit.
  • the container unit is typically made of a plastic material, for example, by a method of deep drawing and/or injection moulding.
  • the matrix form is typically based on the principle of weekly filling; in other words, the number of columns in the matrix form is seven, corresponding to the days of a week, and the number of rows varies typically from four to six, even eight.
  • Each row is intended for a dose of medicine to be administered at a given time each day, and different times of administration are assigned to different rows for the dose of medicine in question; for example, seen from the top down in the use position of the container unit, four rows of the container unit define the purpose of use for the row in question: the morning dose, the daytime dose, the evening dose, and the night dose.
  • Container units of this kind are presented in the publications US 5,174,451 and US 5,379,899 . The container unit according to the latter publication is commercially available (registered trademark DOSETT).
  • the container unit according to US 5,379,899 comprises structurally an integral compartmented base of a rectangular shape to be placed inside a box-like container unit and to be closed inside by an openable lid part.
  • the top part of the frame of the container unit is equipped with seven preferably transparent lid strips that are manually movable on the support of guides in the frame in the longitudinal direction of each column.
  • the upper part of the compartment in turn for use can be opened and the dose of medicine can be removed from the compartment.
  • the edge parts of the frame of the container unit are equipped with markings of the day of the week by the columns and with markings of the time of administration of the dose by the rows.
  • the device for monitoring the administration of doses comprises a space in which a container unit of n ⁇ m matrix form can be placed in a releasable manner to cooperate with an alarm and reminder system of the device of monitoring the administration of doses.
  • the space where the container unit is to be placed in the device for monitoring the administration of doses is functionally easy to use, it is easy to take along the container unit with simple measures when leaving the location where the device for monitoring the administration of doses is kept, as well as it is easy to remove the container unit for the administration of a dose of medicine and further for the weekly refilling of the container unit.
  • the application of the device for monitoring the administration of doses shown in Fig. 1 , has the general design of a rectangular plate.
  • the main elements visible to the user are, from the right-hand side of Fig. 1 , a programming and display unit 1, a field 2 for receiving a container unit S ( Fig. 2 ) in connection with the monitoring device, and an alarm and reminder unit 3.
  • the elements 1 to 3 together with the programmable data processing unit inside the casing of the monitoring device and advantageously with remote connections provided in the device, constitute the alarm and reminder system of the monitoring device.
  • the container unit S shown in Fig. 2 and placed in the monitoring device, contains doses of medicine (not shown) arranged in different compartments according to the schedule of administration of the doses.
  • the upper surface of the monitoring device may comprise text 4 or corresponding information to explain the use of the monitoring device.
  • the device for monitoring the administration of doses can be coupled via a transformer (not shown in the figures) to an electrical power network by a connection cord 5.
  • the device comprises a battery as a backup power supply.
  • a data processing unit consisting of programmable electronic circuits is placed inside the casing.
  • the programming and display unit 1 comprises a display 1 a, programming and function keys 1b (in the application, four keys in a row) and an alarm key 1c, all connected to the data processing unit.
  • programming and function keys 1b programming data of the data processing unit as well as various instructions and data for the user of the monitoring device, for example, about the dose of medicine to be administered at the time, can be displayed on the display 1a.
  • the field 2 which is preferably a planar rectangular recess 2a extending downwards from the upper surface of the monitoring device and having the size corresponding to the rectangular bottom surface of the container unit S, comprises a coupling element 2b connected to the data processing unit and indicating that the container unit S is either placed in the field S for the monitoring device, or detached from it.
  • the coupling element 2b may be, for example, a mechano-electrical micro-switch, or a sensor operating on contactless principle.
  • the field 2 may be an area limited by elevated stoppers, such as elongated edges, normally a structure formed in the upper surface of the device of a type in which the container unit can be placed in a given position defined by the stoppers. Consequently, the monitoring device comprises a space in which the container unit S can be placed in a given position to cooperate with the automatic alarm and reminder system of the device.
  • elevated stoppers such as elongated edges
  • the alarm and reminder system 3 coupled to the data processing unit consists, in its visual appearance, of four pairs I to IV of indicators, preferably electrical colour indicators 3a, 3b. They are aligned in the upper surface of the monitoring device in the longitudinal direction of the edge parallel with the columns of the n ⁇ m matrix form of the container unit of the field 2.
  • the colour indicators 3a, 3b may be, for example, colour LEDs (light-emitting diodes).
  • the monitoring device shown in the figures is thus intended for such an application of the container unit S that comprises, for each day of the week, four times of administering a dose of medicine; in other words, the n ⁇ m matrix form is 4 ⁇ 7.
  • Each colour indicator pair 3a, 3b is placed by a given row in the matrix form, for example in such a way (Fig- 2) that I, II, III and IV correspond to the locations of the compartments for doses of medicine to be taken in the morning, in the daytime, in the evening and at night, respectively, when the container unit is placed in the field 2.
  • the alarm and reminder unit 3 also comprises a buzzer device 3c, which can be used to support the alarm and reminder functions in the form of acoustic signals.
  • the indicators are arrayed in a vertical row on the left-hand side of the field, but alternatively, they can be arrayed on the right-hand side of the field.
  • the device for monitoring the administration of doses operates in the following way:
  • the container unit S is refilled weekly with the doses of medicine prescribed for each day and time of administration in such a way that the medication for the whole week is stored in the container unit S.
  • the container unit S is then placed in the field 2 ( Fig. 2 ), wherein the monitoring device receives this information by means of the coupling element 2b.
  • the container unit can be filled by a person other than the user, for example by a home aid. Consequently, the container unit S is a container unit for doses of medicine, which can be used several times and which can be refilled from the actual packages of medicine.
  • the data processing unit of the monitoring device comprises a timer in which the times of the day when a given dose of medicine should be administered can be programmed with the keys 1 b of the programming and display unit 1, in advance when the monitoring device is taken into use, or when the medication regime is changed.
  • the monitoring device gives an alarm; in other words, the first LED 3a, preferably a LED with green colour, placed by the row corresponding to the time of administration of said dose of medicine, is lit. The green colour thus indicates that the dose of medicine is available to be administered.
  • this visual alarm signal is also combined with an acoustic signal from the buzzer device 3c.
  • the container unit S is detached from the field 2 of the monitoring device for the administration of the dose of medicine.
  • the time of detachment is recorded by the coupling element 2b, preferably a micro-switch.
  • the administration of the dose of medicine is recorded in the data processing unit as being completed after the container unit S has stayed detached from the field 2 for a required minimum time recorded in the programming and display unit 1.
  • the first, green LED 3a is turned off and the second LED 3b, preferably of red colour, is lit to indicate that the dose of medicine has been administered.
  • the programming may suitably comprise a function that the second, red LED 3b is turned off after a given time; in other words, none of the LEDs 3a, 3b (I-IV) is on, wherein the status indicated by the monitoring device is: the preceding dose of medicine has been taken, a certain time has passed from its administration, and it is not yet time to administer the next dose of medicine.
  • the indicator of the respective compartment (the indicator at the end of the row of compartments containing said compartment) is turned to a state in which it has the colour allowing the administration, preferably green; that is, when the indicator is a pair of visual indicators, the first indicator (LED) 3a is lit and the second one 3b is turned off.
  • An auxiliary function programmed in the data processing unit of the monitoring device is that if the administration of a dose of medicine is not recorded within a given time after the above-presented first alarm, a second alarm, a "reminder alarm", will be given, which may be of a different type, for example a different acoustic signal and/or a different visual signal; for example, a blinking function begins in the green LED 3a.
  • a special alarm function is preferably programmed in the data processing unit of the device, which will be activated when a given time has passed from the time of the first alarm (the programmed time of administration of the dose).
  • This special alarm is programmed to be sent outside the location where the monitoring device is kept, via a wired or wireless communication line (for example, GSM) (not shown in the drawings).
  • GSM wireless communication line
  • Such a special "remote alarm” may be a third alarm; in other words, it follows the above-described reminder alarm, or it may be directly the second alarm.
  • the telephone number, to which the remote alarm will be sent can be programmed in the device in advance.
  • Such a remote alarm may also be combined with an audio and/or light signal given by the device.
  • the data processing unit of the monitoring device may also comprise other programmable properties; for example, if the container unit is redetached from the monitoring device before it is time to take the next dose of medicine, the monitoring device may indicate, in the absence of other operations, a malfunction by giving a visual and/or acoustic warning signal which may be, for example, a blinking function of the second, red LED 3b and/or a sound different from the above-mentioned acoustic signals via the buzzer 3c.
  • a visual and/or acoustic warning signal which may be, for example, a blinking function of the second, red LED 3b and/or a sound different from the above-mentioned acoustic signals via the buzzer 3c.
  • the programming of the monitoring device also comprises a by-pass function; that is, if the container unit S is taken along when leaving the location where the monitoring device is kept, this information can be entered in the data processing unit of the monitoring device.
  • the by-pass function can be set to last for a short time or a longer time, to avoid unnecessary alarms.
  • the programming may comprise a function, by which data relating to the dose of medicine which is being taken can be shown on the display 1a.
  • the monitoring device also comprises an alarm key 1c, which can be pressed preferably continuously, for example for 0.5 seconds, to send a special alarm as a remote alarm outside the location where the monitoring device is kept, for example to an emergency centre, an outpatient department, the doctor in charge of the treatment, a nurse, and/or a home aid. Consequently, the monitoring device may communicate with one or more external supervisors having different authorizations to change the programming of the monitoring device and/or to monitor the function of the monitoring device, wherein e.g. a wired or wireless data transmission connection (for example, GSM) is used in the communication.
  • GSM wireless data transmission connection
  • a doctor can monitor the treatment, and in the case of a duplex connection, the doctor can also program the monitoring device by remote control.
  • various instructions in the data processing unit of the monitoring device such as the quantities of doses of medicine, other instructions such as instructions for meals and excercises which can be shown on the display 1 a, etc.
  • the monitoring device contains a security function for backup, said security function allowing only a change of a given quantity, one way or the other, in the values relating to the administration of the drug dose (time of day, quantity of the dose of medicine), i.e. an upper limit is determined for the changes.
  • the methods and targets of data transmission described here can also be used for implementing the above-described automatic remote alarm function following a failure to administer a dose.
  • the above-described functions thus occur normally in such a way that, for example on Wednesday, at the time to take the daytime dose, the first, green LED 3a of the pair of indicators 11 is lit, wherein the user removes the container unit S from the monitoring device in the direction of arrow P.
  • the display unit shows the corresponding data as well as a notice of the content of the dose of medicine.
  • the user grips the handle V of a lid strip KS by the column corresponding to Wednesday, and pulls the lid strip KS outwards, as shown by arrow AV, outside the container unit S so that the opposite end of the lid strip passes the row corresponding to the placement of the daytime dose of medicine, i.e.
  • the lid strip KS is returned to its initial position and the container unit S is placed in the direction of arrow AS into the field 2 of the monitoring device.
  • the second, red LED 3b of the pair of indicators II is lit, and said administration of the dose of medicine is recorded in the data processing unit of the monitoring device as being correctly completed.
  • the second, red LED 3b of the pair of indicators II is also turned off.
  • the visual and acoustic signals can be designed and programmed to function in such a way that during the time of administering a dose of medicine and the removal of the container unit S, only one visual indicator is used, for example a green LED, and after a given time, an acoustic reminder is given, if the administration of the dose of medicine has not been recorded in the data processing unit before that.
  • the functions corresponding to those described above can be substantially implemented by only one visual indicator placed by each row.
  • edge of the field 2 parallel with the rows with a row of indicators on the upper surface of the monitoring device (a total of seven indicators, one by each column, place 6 in Fig. 1 ), which indicates the actual day of the week with, for example, red colour.
  • Figure 3 shows an embodiment that takes into account the possibility of container units S of different sizes.
  • the field 2 is dimensioned according to the largest thinkable container unit, and its structure may be the above-mentioned recess or area defined by stoppers.
  • the coupling element 2b is placed in that part of the field which is covered by the smallest thinkable container unit S.
  • a container unit S smaller than the size of the field is placed in one corner of the field, and the rest of the field 2 can be covered by a separate angle piece KP.
  • the stoppers limiting the field from above and from the side can be arranged to be movable on two sides of the field (the sides joined in the corner opposite to said corner of placement of the container unit).
  • the figure also shows how the visual portion of the reminder unit 3, which is parallel to one side of the field and simultaneously the container unit, may consist of a continuous visual structure, such as a display screen, which can be provided, by means of display technology, with a visual indicator 3a, 3b placed by the respective row and operating in a way similar to above-mentioned colour indicators, and which does not necessarily need to be coloured but may also be black-and-white.
  • the locations, in which the indicators will exist, can be programmed by means of the data processing unit of the device.
  • the invention is not limited solely to the described container unit type. If use is sometimes made of units in which the locations corresponding to different times of the day are arranged in the matrix form in different columns, the indicators in the monitoring device designed for this purpose may be placed next to each column, that is, in a row above or below the field.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • External Artificial Organs (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP20050107739 2004-08-23 2005-08-23 Device for monitoring the administration of doses Not-in-force EP1629822B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20040302 FI6433U1 (fi) 2004-08-23 2004-08-23 Annosten oton valvontalaite

Publications (3)

Publication Number Publication Date
EP1629822A2 EP1629822A2 (en) 2006-03-01
EP1629822A3 EP1629822A3 (en) 2006-07-05
EP1629822B1 true EP1629822B1 (en) 2008-06-11

Family

ID=32922069

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20050107739 Not-in-force EP1629822B1 (en) 2004-08-23 2005-08-23 Device for monitoring the administration of doses

Country Status (4)

Country Link
EP (1) EP1629822B1 (fi)
AT (1) ATE397915T1 (fi)
DE (1) DE602005007434D1 (fi)
FI (1) FI6433U1 (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006028726A1 (de) * 2006-06-20 2007-12-27 Breiner, Karl-Heinz, Dr. Vorrichtung zur kontrollierten Verabreichung von Medikamenten an einen Patienten
WO2008064428A1 (en) * 2006-11-29 2008-06-05 Bray Kenmar Medicament dispensing device
NL1034522C2 (nl) * 2007-10-16 2009-04-20 Bb Health Innovations Medicijnendoos met berichtfunctie en houder.
WO2014056223A1 (zh) * 2012-10-14 2014-04-17 Wang Shujie 记忆药盒
WO2014056224A1 (zh) * 2012-10-14 2014-04-17 Wang Shujie 记忆药架
CN203060338U (zh) * 2013-01-23 2013-07-17 北京工业设计促进中心 智能药盒
EP3445309A4 (en) * 2016-04-18 2019-11-06 Finn Medicinen Scandinavia AB SYSTEM, DEVICE AND COMPUTER PROCESS FOR MONITORING THE USE OF MEDICAMENTS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4028068A1 (de) * 1990-09-05 1992-03-12 Wilhelm Stoerk Temperatur Mess Vorrichtung zur ueberwachung der regelmaessigen einnahme von medikamenten
US5710551A (en) * 1995-07-26 1998-01-20 Ridgeway; Donald G. Self-medication monitoring system
FR2818124B1 (fr) * 2000-12-18 2005-11-18 Rene Peyran Pilulier electronique programmable pour la distribution interactive de medicaments ou d'ampoules buvables
AUPS111002A0 (en) * 2002-03-13 2002-04-18 Ayre, Peter Joseph An electronic pill packet holder and reminder that detects pill packet removal

Also Published As

Publication number Publication date
EP1629822A3 (en) 2006-07-05
FIU20040302U0 (fi) 2004-08-23
FI6433U1 (fi) 2004-10-28
EP1629822A2 (en) 2006-03-01
DE602005007434D1 (de) 2008-07-24
ATE397915T1 (de) 2008-07-15

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