EP1610129A3 - Verfahren und Vorrichtung zur Herstellung von bindungsfähigen Reagenzträgern - Google Patents

Verfahren und Vorrichtung zur Herstellung von bindungsfähigen Reagenzträgern Download PDF

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Publication number
EP1610129A3
EP1610129A3 EP05013260A EP05013260A EP1610129A3 EP 1610129 A3 EP1610129 A3 EP 1610129A3 EP 05013260 A EP05013260 A EP 05013260A EP 05013260 A EP05013260 A EP 05013260A EP 1610129 A3 EP1610129 A3 EP 1610129A3
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EP
European Patent Office
Prior art keywords
carrier body
reagent carrier
treatment
der
preparation device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP05013260A
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English (en)
French (fr)
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EP1610129A2 (de
EP1610129B1 (de
Inventor
Hans Hornauer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Roche Diagnostics GmbH
Original Assignee
F Hoffmann La Roche AG
Roche Diagnostics GmbH
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Filing date
Publication date
Application filed by F Hoffmann La Roche AG, Roche Diagnostics GmbH filed Critical F Hoffmann La Roche AG
Publication of EP1610129A2 publication Critical patent/EP1610129A2/de
Publication of EP1610129A3 publication Critical patent/EP1610129A3/de
Application granted granted Critical
Publication of EP1610129B1 publication Critical patent/EP1610129B1/de
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
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    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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    • B01J2219/0063—Other, e.g. van der Waals forces, hydrogen bonding
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    • B01J2219/00583—Features relative to the processes being carried out
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    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632—Introduction of reactive groups to the surface
    • B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Abstract

Die Erfindung betrifft ein Verfahren zur Herstellung von bindungsfähigen und zur Bestimmung von Analyten in Flüssigkeiten geeigneten Reagenzträgern, wobei das Verfahren wenigstens einen Schritt der Behandlung eines jeweiligen Reagenzträgerkörpers (4) insbesondere durch Materialübergabe zwischen einer Behandlungseinrichtung (12) und dem Reagenzträgerkörper (4) in einer Präparationsvorrichtung umfasst, wobei dieser Behandlungsschritt
  • am bewegten Reagenzträgerkörper (4) während seines Transports in der Präparationsvorrichtung oder
  • während einer Bewegung der Behandlungseinrichtung relativ zum Reagenzträgerkörper in der Präparationsvorrichtung erfolgt.
EP05013260A 2004-06-21 2005-06-20 Verfahren und Vorrichtung zur Herstellung von bindungsfähigen Reagenzträgern Not-in-force EP1610129B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004029909 2004-06-21
DE102004029909A DE102004029909A1 (de) 2004-06-21 2004-06-21 Verfahren und Vorrichtung zur Herstellung von bindungsfähigen Reagenzträgern

Publications (3)

Publication Number Publication Date
EP1610129A2 EP1610129A2 (de) 2005-12-28
EP1610129A3 true EP1610129A3 (de) 2006-07-05
EP1610129B1 EP1610129B1 (de) 2012-10-24

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
EP05013260A Not-in-force EP1610129B1 (de) 2004-06-21 2005-06-20 Verfahren und Vorrichtung zur Herstellung von bindungsfähigen Reagenzträgern

Country Status (11)

Country Link
US (2) US7608466B2 (de)
EP (1) EP1610129B1 (de)
JP (1) JP2006010690A (de)
KR (1) KR101080024B1 (de)
CN (1) CN1712969A (de)
AU (1) AU2005202528B2 (de)
BR (1) BRPI0502150A (de)
CA (1) CA2510125C (de)
DE (1) DE102004029909A1 (de)
MX (1) MXPA05006324A (de)
SG (1) SG118365A1 (de)

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Publication number Priority date Publication date Assignee Title
KR20130091745A (ko) 2010-07-19 2013-08-19 에프. 호프만-라 로슈 아게 항암요법에 반응할 가능성이 증가된 환자를 확인하는 방법
WO2012010549A1 (en) 2010-07-19 2012-01-26 F. Hoffmann-La Roche Ag Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy
BR112012033423A2 (pt) 2010-07-19 2016-10-25 Hoffmann La Roche métodos para melhorar a eficácia do tratamento de um regime de quimioterapia e in vitro, usos de bevacizumab e de sondas específicas, kit e uso de um polipeptídeo
RU2013106938A (ru) 2010-07-19 2014-08-27 Ф.Хоффманн-Ля Рош Аг Биомаркеры в плазме крови, предназначенные для комбинированных терапий с использованием бевацизумаба при лечении рака молочной железы
WO2012058632A1 (en) 2010-10-29 2012-05-03 Thermo Fisher Scientific Oy Automated system for sample preparation and analysis
SG11201402737SA (en) 2011-12-05 2014-06-27 Hoffmann La Roche Blood plasma biomarkers for bevacizumab combination therapies for treatment of breast cancer
JP2015522815A (ja) 2012-06-26 2015-08-06 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト 乳癌の治療用ベバシズマブ併用療法の血漿バイオマーカー
CN108027379B (zh) 2015-06-26 2021-07-23 雅培实验室 用于诊断分析设备的反应容器交换装置
WO2018011344A1 (en) 2016-07-15 2018-01-18 F. Hoffmann-La Roche Ag Method and means for detecting the level of total vegf-a

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EP1610129A2 (de) 2005-12-28
KR20060046403A (ko) 2006-05-17
DE102004029909A1 (de) 2006-01-19
AU2005202528B2 (en) 2011-12-01
EP1610129B1 (de) 2012-10-24
CA2510125A1 (en) 2005-12-21
SG118365A1 (en) 2006-01-27
BRPI0502150A (pt) 2006-04-11
JP2006010690A (ja) 2006-01-12
KR101080024B1 (ko) 2011-11-04
AU2005202528A1 (en) 2006-01-12
CA2510125C (en) 2010-03-09
CN1712969A (zh) 2005-12-28
US7608466B2 (en) 2009-10-27
MXPA05006324A (es) 2006-01-09
US20050282235A1 (en) 2005-12-22

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