EP1581637A4 - Materiels a base de cellules souches humaines et procedes correspondant - Google Patents

Materiels a base de cellules souches humaines et procedes correspondant

Info

Publication number
EP1581637A4
EP1581637A4 EP03781813A EP03781813A EP1581637A4 EP 1581637 A4 EP1581637 A4 EP 1581637A4 EP 03781813 A EP03781813 A EP 03781813A EP 03781813 A EP03781813 A EP 03781813A EP 1581637 A4 EP1581637 A4 EP 1581637A4
Authority
EP
European Patent Office
Prior art keywords
methods
stem cell
human stem
cell materials
materials
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03781813A
Other languages
German (de)
English (en)
Other versions
EP1581637A2 (fr
Inventor
Eliezer Huberman
Yong Zhao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Chicago
Original Assignee
University of Chicago
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Chicago filed Critical University of Chicago
Priority to EP11152200A priority Critical patent/EP2357223A3/fr
Publication of EP1581637A2 publication Critical patent/EP1581637A2/fr
Publication of EP1581637A4 publication Critical patent/EP1581637A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0607Non-embryonic pluripotent stem cells, e.g. MASC
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/22Colony stimulating factors (G-CSF, GM-CSF)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]
    • C12N2501/2306Interleukin-6 (IL-6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]
    • C12N2501/235Leukemia inhibitory factor [LIF]
EP03781813A 2002-11-07 2003-11-07 Materiels a base de cellules souches humaines et procedes correspondant Withdrawn EP1581637A4 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP11152200A EP2357223A3 (fr) 2002-11-07 2003-11-07 CELLULES SOUCHES HUMAINES et PROCÉDÉ DE UTILISATION

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42444202P 2002-11-07 2002-11-07
US424442P 2002-11-07
PCT/US2003/035538 WO2004043990A2 (fr) 2002-11-07 2003-11-07 Materiels a base de cellules souches humaines et procedes correspondant

Publications (2)

Publication Number Publication Date
EP1581637A2 EP1581637A2 (fr) 2005-10-05
EP1581637A4 true EP1581637A4 (fr) 2007-04-25

Family

ID=32312808

Family Applications (2)

Application Number Title Priority Date Filing Date
EP03781813A Withdrawn EP1581637A4 (fr) 2002-11-07 2003-11-07 Materiels a base de cellules souches humaines et procedes correspondant
EP11152200A Withdrawn EP2357223A3 (fr) 2002-11-07 2003-11-07 CELLULES SOUCHES HUMAINES et PROCÉDÉ DE UTILISATION

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP11152200A Withdrawn EP2357223A3 (fr) 2002-11-07 2003-11-07 CELLULES SOUCHES HUMAINES et PROCÉDÉ DE UTILISATION

Country Status (4)

Country Link
EP (2) EP1581637A4 (fr)
JP (1) JP2006512060A (fr)
CA (1) CA2505394C (fr)
WO (1) WO2004043990A2 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI288779B (en) 2002-03-28 2007-10-21 Blasticon Biotech Forschung Dedifferentiated, programmable stem cells of monocytic origin, and their production and use
JP3762975B2 (ja) 2003-03-18 2006-04-05 学校法人慶應義塾 単球由来多能性細胞momc
US20050260158A1 (en) * 2003-11-07 2005-11-24 Eliezer Huberman Human stem cell materials and methods
EP1600500A1 (fr) * 2004-05-27 2005-11-30 Georg-August-Universität Göttingen Méthode de production de cellules pluripotentes a partir de monocytes
AU2006202318A1 (en) * 2005-06-02 2006-12-21 Wing-Yee Chan The preparation of multipotent stem cells and the use thereof
US9155762B2 (en) 2005-12-08 2015-10-13 University Of Louisville Research Foundation, Inc. Uses and isolation of stem cells from bone marrow
CN101573441A (zh) * 2005-12-08 2009-11-04 路易斯维尔大学研究基金会有限公司 非常小的胚胎样(vsel)干细胞及分离和利用其的方法
ITRM20060498A1 (it) * 2006-09-20 2008-03-21 Alessandra Gambacurta Metodo di espansione di cellule staminali adulte da sangue periferico e relativi usi in campo medico
ITUD20080058A1 (it) * 2008-03-18 2009-09-19 Thankstem S R L Kit per la raccolta di sangue, preferibilmente periferico, per la produzione di cellule staminali
US10271876B2 (en) 2011-11-23 2019-04-30 Mezadata Medical Ip Holding Llc Method of in vitro fertilization with delay of embryo transfer and use of peripheral blood mononuclear cells
WO2015170291A1 (fr) 2014-05-09 2015-11-12 Thankstem S.R.L. Procédé d'expansion de cellules souches adultes à partir de sang total
US11312940B2 (en) 2015-08-31 2022-04-26 University Of Louisville Research Foundation, Inc. Progenitor cells and methods for preparing and using the same
EP3423568A4 (fr) 2016-03-04 2019-11-13 University Of Louisville Research Foundation, Inc. Procédés et compositions pour l'expansion ex vivo de très petites cellules souches de type embryonnaire (vsel)
CN111808800B (zh) * 2020-07-20 2022-08-26 中南大学湘雅二医院 一种体外诱导免疫抑制性髓系抑制细胞及其制备和应用
CN113667637B (zh) * 2021-08-05 2023-06-16 大连医科大学 一种体外诱导人外周MDSCs分化和扩增的方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020001826A1 (en) * 1999-12-22 2002-01-03 Wager Ruth E. Hematopoietic cells and methods based thereon
DE10214095C1 (de) * 2002-03-28 2003-09-25 Bernd Karl Friedrich Kremer Dedifferenzierte, programmierbare Stammzellen monozytären Ursprungs, sowie deren Herstellung und Verwendung
WO2003083092A1 (fr) * 2002-03-28 2003-10-09 Blasticon Biotechnologische Forschung Gmbh Cellules souches dedifferenciees programmables d'origine monocytique, production et utilisation de ces dernieres

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US424442A (en) 1890-03-25 Chusetts
US6534055B1 (en) * 1988-11-23 2003-03-18 Genetics Institute, Inc. Methods for selectively stimulating proliferation of T cells
CA2107897A1 (fr) * 1991-04-09 1992-10-10 Ronald Hoffman Systeme et procede de stimulation des cellules hematopoietiques
WO1993012805A1 (fr) * 1992-01-02 1993-07-08 Regents Of The University Of Michigan Procede de regulation des lignages cellulaires humains hematopoeïtiques
US5733541A (en) * 1995-04-21 1998-03-31 The Regent Of The University Of Michigan Hematopoietic cells: compositions and methods
CA2307807C (fr) * 1997-10-23 2008-09-02 Andrea G. Bodnar Procedes et matieres utiles pour la croissance de cellules souches primordiales de primate
US6274378B1 (en) * 1997-10-27 2001-08-14 The Rockefeller University Methods and compositions for obtaining mature dendritic cells
US6586192B1 (en) * 1998-05-29 2003-07-01 Thomas Jefferson University Compositions and methods for use in affecting hematopoietic stem cell populations in mammals
AU774876B2 (en) * 1999-06-29 2004-07-08 Board Of Trustees Of The Leland Stanford Junior University Mammalian myeloid progenitor cell subsets
WO2001062895A2 (fr) * 2000-02-24 2001-08-30 Xcyte Therapies, Inc. Stimulation et concentration simultanees de cellules

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020001826A1 (en) * 1999-12-22 2002-01-03 Wager Ruth E. Hematopoietic cells and methods based thereon
DE10214095C1 (de) * 2002-03-28 2003-09-25 Bernd Karl Friedrich Kremer Dedifferenzierte, programmierbare Stammzellen monozytären Ursprungs, sowie deren Herstellung und Verwendung
WO2003083092A1 (fr) * 2002-03-28 2003-10-09 Blasticon Biotechnologische Forschung Gmbh Cellules souches dedifferenciees programmables d'origine monocytique, production et utilisation de ces dernieres
EP1506999A1 (fr) * 2002-03-28 2005-02-16 Blasticon Biotechnologische Forschung GmbH Cellules souches dédifférenciées programmables d'origine mocytaire, leur production et leur utilisation

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BYKOVSKAIA S.N. ET AL.: "Differentiation of immunostimulatory stem-cell- and monocyte-derived dendritic cells involves maturation of intracellular compartments responsible for antigen presentation and secretion", STEM CELLS, vol. 20, September 2002 (2002-09-01) - September 2002 (2002-09-01), pages 380 - 393, XP002423999 *
CLAUSENJ. ET AL.: "Blood-derived macrophage layers in the presence of hydrocortisone support myeloid progenitors in long-term cultures of CD34+ cord blood and bone marrow cells", ANNUAL HEMATOLOGY, vol. 79, February 2000 (2000-02-01) - February 2000 (2000-02-01), pages 59 - 65, XP002423998 *
ZHAO YONG ET AL: "A human peripheral blood monocyte-derived subset acts as pluripotent stem cells", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 100, no. 5, 4 March 2003 (2003-03-04), pages 2426 - 2431, XP002410596, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
EP2357223A2 (fr) 2011-08-17
WO2004043990A3 (fr) 2005-02-03
CA2505394C (fr) 2014-05-13
EP1581637A2 (fr) 2005-10-05
WO2004043990A2 (fr) 2004-05-27
CA2505394A1 (fr) 2004-05-27
EP2357223A3 (fr) 2012-11-07
JP2006512060A (ja) 2006-04-13

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