EP1564299A4 - Verfahren zum screening nach verbindungen, die die enzymatische aktivität des gwt1 genproduktes hemmen - Google Patents
Verfahren zum screening nach verbindungen, die die enzymatische aktivität des gwt1 genproduktes hemmenInfo
- Publication number
- EP1564299A4 EP1564299A4 EP03774148A EP03774148A EP1564299A4 EP 1564299 A4 EP1564299 A4 EP 1564299A4 EP 03774148 A EP03774148 A EP 03774148A EP 03774148 A EP03774148 A EP 03774148A EP 1564299 A4 EP1564299 A4 EP 1564299A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- inhibit
- compounds
- screening
- gene product
- enzymatic activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002339418 | 2002-11-22 | ||
JP2002339418 | 2002-11-22 | ||
PCT/JP2003/014909 WO2004048604A1 (ja) | 2002-11-22 | 2003-11-21 | Gwt1遺伝子産物の酵素活性を阻害する化合物をスクリーニングする方法 |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1564299A1 EP1564299A1 (de) | 2005-08-17 |
EP1564299A4 true EP1564299A4 (de) | 2006-07-05 |
EP1564299B1 EP1564299B1 (de) | 2007-06-20 |
Family
ID=32375774
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP03774148A Expired - Lifetime EP1564299B1 (de) | 2002-11-22 | 2003-11-21 | Verfahren zum screening nach verbindungen, die die enzymatische aktivität des gwt1 genproduktes hemmen |
Country Status (8)
Country | Link |
---|---|
US (1) | US8323917B2 (de) |
EP (1) | EP1564299B1 (de) |
JP (1) | JP4061309B2 (de) |
CN (1) | CN100371456C (de) |
AT (1) | ATE365224T1 (de) |
AU (1) | AU2003284635A1 (de) |
DE (1) | DE60314538T2 (de) |
WO (1) | WO2004048604A1 (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2286387C2 (ru) * | 2000-07-07 | 2006-10-27 | Эйсай Ко., Лтд. | Ген синтеза клеточной стенки грибков |
KR20070065452A (ko) * | 2002-11-22 | 2007-06-22 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 말라리아 기생충에서 gpi의 생합성을 억제하는 화합물을스크리닝하는 방법 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9400600A (pt) * | 1994-02-17 | 1995-10-24 | Finep Financiadora De Estudos | Processos para produção de uma protéina recombinante e/ou de glicosilfosfatidilinositol (GPI) em células de microorganismos eucariontes e para a obtenção de leveduras de S. cerevisae; célula de levedura sequência de nucleotídios; meio de cultura; medicamento ou vacina; e produto dos ditos processos |
US6747137B1 (en) * | 1998-02-13 | 2004-06-08 | Genome Therapeutics Corporation | Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics |
RU2286387C2 (ru) * | 2000-07-07 | 2006-10-27 | Эйсай Ко., Лтд. | Ген синтеза клеточной стенки грибков |
CN100467598C (zh) * | 2000-07-07 | 2009-03-11 | 卫材R&D管理有限公司 | 真菌细胞壁合成基因 |
JP2004515235A (ja) * | 2000-12-08 | 2004-05-27 | ノボ ノルディスク アクティーゼルスカブ | Tffペプチド |
JP2005168301A (ja) | 2001-12-28 | 2005-06-30 | Eisai Co Ltd | 真菌細胞壁合成阻害活性を有する化合物をスクリーニングする方法 |
KR20070065452A (ko) | 2002-11-22 | 2007-06-22 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 말라리아 기생충에서 gpi의 생합성을 억제하는 화합물을스크리닝하는 방법 |
-
2003
- 2003-11-21 US US10/536,935 patent/US8323917B2/en not_active Expired - Fee Related
- 2003-11-21 DE DE60314538T patent/DE60314538T2/de not_active Expired - Lifetime
- 2003-11-21 AU AU2003284635A patent/AU2003284635A1/en not_active Abandoned
- 2003-11-21 CN CNB2003801091169A patent/CN100371456C/zh not_active Expired - Fee Related
- 2003-11-21 EP EP03774148A patent/EP1564299B1/de not_active Expired - Lifetime
- 2003-11-21 AT AT03774148T patent/ATE365224T1/de not_active IP Right Cessation
- 2003-11-21 JP JP2004555006A patent/JP4061309B2/ja not_active Expired - Lifetime
- 2003-11-21 WO PCT/JP2003/014909 patent/WO2004048604A1/ja active IP Right Grant
Non-Patent Citations (1)
Title |
---|
KINOSHITA TAROH ET AL: "Dissecting and manipulating the pathway for glycosylphosphatidylinosi tol-anchor biosynthesis", CURRENT OPINION IN CHEMICAL BIOLOGY, vol. 4, no. 6, December 2000 (2000-12-01), pages 632 - 638, XP002370586, ISSN: 1367-5931 * |
Also Published As
Publication number | Publication date |
---|---|
DE60314538D1 (de) | 2007-08-02 |
ATE365224T1 (de) | 2007-07-15 |
JP4061309B2 (ja) | 2008-03-19 |
EP1564299B1 (de) | 2007-06-20 |
JPWO2004048604A1 (ja) | 2006-03-23 |
AU2003284635A8 (en) | 2004-06-18 |
AU2003284635A1 (en) | 2004-06-18 |
CN100371456C (zh) | 2008-02-27 |
EP1564299A1 (de) | 2005-08-17 |
WO2004048604A1 (ja) | 2004-06-10 |
US8323917B2 (en) | 2012-12-04 |
DE60314538T2 (de) | 2008-02-28 |
US20060240429A1 (en) | 2006-10-26 |
CN1742095A (zh) | 2006-03-01 |
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