EP1556035A4 - Nouveaux composes aromatiques possedant une activite antifongique ou antibacterienne - Google Patents
Nouveaux composes aromatiques possedant une activite antifongique ou antibacterienneInfo
- Publication number
- EP1556035A4 EP1556035A4 EP03759497A EP03759497A EP1556035A4 EP 1556035 A4 EP1556035 A4 EP 1556035A4 EP 03759497 A EP03759497 A EP 03759497A EP 03759497 A EP03759497 A EP 03759497A EP 1556035 A4 EP1556035 A4 EP 1556035A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- aromatic compounds
- antibacterial activity
- compounds possessing
- novel aromatic
- possessing antifungal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/42—Nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/42—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41241002P | 2002-09-20 | 2002-09-20 | |
US412410P | 2002-09-20 | ||
PCT/US2003/030121 WO2004026264A2 (fr) | 2002-09-20 | 2003-09-18 | Nouveaux composes aromatiques possedant une activite antifongique ou antibacterienne |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1556035A2 EP1556035A2 (fr) | 2005-07-27 |
EP1556035A4 true EP1556035A4 (fr) | 2006-09-13 |
Family
ID=32030862
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP03759497A Withdrawn EP1556035A4 (fr) | 2002-09-20 | 2003-09-18 | Nouveaux composes aromatiques possedant une activite antifongique ou antibacterienne |
Country Status (4)
Country | Link |
---|---|
US (1) | US7141680B2 (fr) |
EP (1) | EP1556035A4 (fr) |
AU (1) | AU2003275225A1 (fr) |
WO (1) | WO2004026264A2 (fr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2337162T3 (es) * | 2004-05-12 | 2010-04-21 | Proteotech, Inc. | N-arilbenzamidas sustituidas y compuestos relacionados para el tratamiento de enfermedades de amiloides y sinucleinopatias. |
CN101142194B (zh) * | 2005-03-14 | 2012-10-10 | 顶点制药有限责任公司 | 吲哚衍生物,组合物及用作β-分泌酶抑制剂的方法 |
EP1873144B1 (fr) * | 2005-04-20 | 2014-07-23 | Takeda Pharmaceutical Company Limited | Compose heterocyclique fusionne |
CA2605110A1 (fr) | 2005-04-20 | 2006-11-02 | Merck & Co., Inc. | Derives du benzothiophene |
US7825154B2 (en) * | 2005-08-12 | 2010-11-02 | The United States Of America As Represented By The Secretary Of The Army | Small molecule inhibitors of botulinum neurotoxins |
AU2013202450B2 (en) * | 2005-08-12 | 2014-12-18 | United States Government As Represented By The Secretary Of The United States Army And The U.S. Army Medical Research & Materiel Command | Broad spectrum antibacterial compounds |
US8921426B2 (en) | 2012-04-18 | 2014-12-30 | International Business Machines Corporation | Cationic bis-urea compounds as effective antimicrobial agents |
US9951097B2 (en) * | 2012-12-04 | 2018-04-24 | The Board Of Trustees Of The University Of Illinois | Antibacterial compounds targeting isoprenoid biosynthesis |
WO2016025692A1 (fr) * | 2014-08-13 | 2016-02-18 | The Scripps Research Institute | Traitement de c9ftd/als par ciblage de séquences de répétition étendues d'arn |
SG11202000217QA (en) * | 2017-07-21 | 2020-02-27 | Antabio Sas | Chemical compounds |
WO2022192162A1 (fr) * | 2021-03-09 | 2022-09-15 | Fox Chase Chemical Diversity Center, Inc. | Nouveaux composés hétéroaromatiques présentant une activité antifongique et leur procédé d'utilisation |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1004974A (en) * | 1963-04-04 | 1965-09-22 | Rhone Poulenc Sa | New amidines, process for their preparation and pharmaceutical compositions containing them |
JPH0827146A (ja) * | 1994-07-15 | 1996-01-30 | Mitsui Toatsu Chem Inc | 2,6−ジ置換インドール誘導体 |
WO2002000650A2 (fr) * | 2000-06-27 | 2002-01-03 | Genelabs Technologies, Inc. | Nouveaux composes possedant une activite anti-bacterienne, antifongique et anti-tumeur |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9623522D0 (en) | 1996-11-11 | 1997-01-08 | Pharmacia & Upjohn Spa | Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents |
GB9806692D0 (en) | 1998-03-27 | 1998-05-27 | Pharmacia & Upjohn Spa | Benzoheterocyclic distamycin derivatives, process for preparing them and their use as antitumour agents |
FR2796279B1 (fr) * | 1999-07-16 | 2001-09-21 | Oreal | Utilisation de l'acide 4,6-dimethoxy-indole 2-carboxylique ou de ses derives pour le traitement de la seborrhee |
WO2001096313A1 (fr) | 2000-06-14 | 2001-12-20 | The Scripps Research Institute | Analogues de distamycine a |
-
2003
- 2003-09-18 EP EP03759497A patent/EP1556035A4/fr not_active Withdrawn
- 2003-09-18 WO PCT/US2003/030121 patent/WO2004026264A2/fr not_active Application Discontinuation
- 2003-09-18 US US10/667,085 patent/US7141680B2/en not_active Expired - Fee Related
- 2003-09-18 AU AU2003275225A patent/AU2003275225A1/en not_active Abandoned
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1004974A (en) * | 1963-04-04 | 1965-09-22 | Rhone Poulenc Sa | New amidines, process for their preparation and pharmaceutical compositions containing them |
JPH0827146A (ja) * | 1994-07-15 | 1996-01-30 | Mitsui Toatsu Chem Inc | 2,6−ジ置換インドール誘導体 |
WO2002000650A2 (fr) * | 2000-06-27 | 2002-01-03 | Genelabs Technologies, Inc. | Nouveaux composes possedant une activite anti-bacterienne, antifongique et anti-tumeur |
Non-Patent Citations (3)
Title |
---|
DYATKINA N B ET AL: "Minor groove DNA binders as antimicrobial agents. 1. Pyrrole tetraamides are potent antibacterials against vancomycin resistant enteroccoci and methicillin resistant staphylococcus aureus", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, vol. 45, no. 4, 2002, pages 805 - 817, XP002238579, ISSN: 0022-2623 * |
PATENT ABSTRACTS OF JAPAN vol. 1996, no. 05 31 May 1996 (1996-05-31) * |
See also references of WO2004026264A2 * |
Also Published As
Publication number | Publication date |
---|---|
AU2003275225A8 (en) | 2004-04-08 |
WO2004026264A3 (fr) | 2004-09-16 |
AU2003275225A1 (en) | 2004-04-08 |
EP1556035A2 (fr) | 2005-07-27 |
US7141680B2 (en) | 2006-11-28 |
WO2004026264A2 (fr) | 2004-04-01 |
US20040063645A1 (en) | 2004-04-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20050419 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL LT LV MK |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20060816 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 31/04 20060101ALI20060809BHEP Ipc: C07D 403/12 20060101ALI20060809BHEP Ipc: C07D 209/04 20060101ALI20060809BHEP Ipc: A61K 31/40 20060101AFI20050517BHEP |
|
17Q | First examination report despatched |
Effective date: 20071107 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20101125 |