EP1501917A4 - Dispositif et procede d'imagerie de cellules analytiques - Google Patents

Dispositif et procede d'imagerie de cellules analytiques

Info

Publication number
EP1501917A4
EP1501917A4 EP03728685A EP03728685A EP1501917A4 EP 1501917 A4 EP1501917 A4 EP 1501917A4 EP 03728685 A EP03728685 A EP 03728685A EP 03728685 A EP03728685 A EP 03728685A EP 1501917 A4 EP1501917 A4 EP 1501917A4
Authority
EP
European Patent Office
Prior art keywords
cell imaging
analytical cell
analytical
imaging
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03728685A
Other languages
German (de)
English (en)
Other versions
EP1501917A2 (fr
Inventor
Michael Trainer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunivest Corp
Original Assignee
Immunivest Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunivest Corp filed Critical Immunivest Corp
Publication of EP1501917A2 publication Critical patent/EP1501917A2/fr
Publication of EP1501917A4 publication Critical patent/EP1501917A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Signal Processing (AREA)
  • Optics & Photonics (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
EP03728685A 2002-05-03 2003-05-05 Dispositif et procede d'imagerie de cellules analytiques Withdrawn EP1501917A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37786802P 2002-05-03 2002-05-03
US377868P 2002-05-03
PCT/US2003/013842 WO2003093795A2 (fr) 2002-05-03 2003-05-05 Dispositif et procede d'imagerie de cellules analytiques

Publications (2)

Publication Number Publication Date
EP1501917A2 EP1501917A2 (fr) 2005-02-02
EP1501917A4 true EP1501917A4 (fr) 2006-04-19

Family

ID=29401578

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03728685A Withdrawn EP1501917A4 (fr) 2002-05-03 2003-05-05 Dispositif et procede d'imagerie de cellules analytiques

Country Status (5)

Country Link
EP (1) EP1501917A4 (fr)
JP (1) JP2005524833A (fr)
AU (1) AU2003234459A1 (fr)
CA (1) CA2484730A1 (fr)
WO (1) WO2003093795A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8137912B2 (en) 2006-06-14 2012-03-20 The General Hospital Corporation Methods for the diagnosis of fetal abnormalities

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2359689B1 (fr) 2002-09-27 2015-08-26 The General Hospital Corporation Dispositif microfluidique pour la séparation de cellules et usage du dispositif
JP4041458B2 (ja) * 2003-12-12 2008-01-30 日立ソフトウエアエンジニアリング株式会社 蛍光ビーズ検出方法及び蛍光ビーズ検出装置
WO2006017811A2 (fr) 2004-08-06 2006-02-16 Compucyte Corporation Absorption de lumiere monochromatique a couleurs multiples et quantification d'absorption de lumiere dans un echantillon colore
EP1810021A1 (fr) * 2004-10-22 2007-07-25 Fermiscan Australia Pty Limited Procede et appareil analytique
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
ES2886923T3 (es) 2005-09-20 2021-12-21 Menarini Silicon Biosystems Spa Métodos y composición para generar sondas de ADN de secuencia única, marcaje de sondas de ADN y el uso de estas sondas
US9134237B2 (en) 2005-09-20 2015-09-15 Janssen Diagnotics, LLC High sensitivity multiparameter method for rare event analysis in a biological sample
FI20051329A0 (fi) 2005-12-27 2005-12-27 Wallac Oy Laitteisto ja menetelmä näytteiden optista mittausta varten
CA2652027C (fr) * 2006-05-12 2017-06-06 Immunivest Corporation Systeme d'eclairage laser en microscopie par fluorescence
EP2029779A4 (fr) 2006-06-14 2010-01-20 Living Microsystems Inc Utilisation de génotypage snp fortement parallèle pour diagnostic fétal
US8372584B2 (en) 2006-06-14 2013-02-12 The General Hospital Corporation Rare cell analysis using sample splitting and DNA tags
US20080050739A1 (en) 2006-06-14 2008-02-28 Roland Stoughton Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
WO2008012724A2 (fr) * 2006-07-20 2008-01-31 Koninklijke Philips Electronics N.V. Suivi optique et détermination de position pour procédés et systèmes de détection
US7782452B2 (en) * 2007-08-31 2010-08-24 Kla-Tencor Technologies Corp. Systems and method for simultaneously inspecting a specimen with two distinct channels
US8143600B2 (en) * 2008-02-18 2012-03-27 Visiongate, Inc. 3D imaging of live cells with ultraviolet radiation
CA3069082C (fr) 2008-09-20 2022-03-22 The Board Of Trustees Of The Leland Stanford Junior University Diagnostic non effractif d'aneuploidie foetale par sequencage
JP5119114B2 (ja) * 2008-09-30 2013-01-16 富士フイルム株式会社 光源装置及び撮影装置
JP4805418B1 (ja) * 2010-03-31 2011-11-02 古河電気工業株式会社 細胞の識別装置及び識別方法
KR20150023022A (ko) 2011-03-24 2015-03-04 앤팩 바이오-메디컬 사이언스 시오., 엘티디. 질병 검출용 마이크로 소자
WO2012151501A2 (fr) * 2011-05-05 2012-11-08 Anpac Bio-Medical Science Co., Ltd. Appareil de détection de cellules tumorales
US20130157347A1 (en) * 2011-07-07 2013-06-20 Veridex, Llc Method of Analyzing Cardiovascular Disorders and Uses Thereof
US9511152B2 (en) * 2012-04-05 2016-12-06 The Board Of Regents Of The University Of Texas System Multicolored pH-activatable fluorescence nanoplatform
CN104914078A (zh) * 2015-04-16 2015-09-16 南京昊控软件技术有限公司 一种大范围多点流体浓度测量系统
SG11201807053TA (en) * 2016-03-07 2018-09-27 X Zell Inc Compositions and methods for identifying rare cells
FR3051556A1 (fr) * 2016-05-18 2017-11-24 Biocytex Utilisation de marqueurs fluorescents pour la detection de cible biologique dans un echantillon

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5034613A (en) * 1989-11-14 1991-07-23 Cornell Research Foundation, Inc. Two-photon laser microscopy
US5127730A (en) * 1990-08-10 1992-07-07 Regents Of The University Of Minnesota Multi-color laser scanning confocal imaging system
US5698397A (en) * 1995-06-07 1997-12-16 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
JP3343276B2 (ja) * 1993-04-15 2002-11-11 興和株式会社 レーザー走査型光学顕微鏡
US5479252A (en) * 1993-06-17 1995-12-26 Ultrapointe Corporation Laser imaging system for inspection and analysis of sub-micron particles

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KAGAN M ET AL: "CellTracks Cell Analysis System for Rare Cell Detection", PROC. SPIE, CONF. CLINICAL DIAGNOSTIC SYSTEMS: TECHNOLOGIES AND INSTRUMENTATION, 22-24 JAN. 2002, SAN JOSE, CA, USA, vol. 4625, June 2002 (2002-06-01), pages 20 - 28, XP002368763 *
TIBBE A G J ET AL: "Imaging Technique Implemented in CellTracks System", CYTOMETRY, vol. 47, 1 April 2002 (2002-04-01), published online 21 March 2002, pages 248 - 255, XP002368764 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8137912B2 (en) 2006-06-14 2012-03-20 The General Hospital Corporation Methods for the diagnosis of fetal abnormalities

Also Published As

Publication number Publication date
WO2003093795A2 (fr) 2003-11-13
AU2003234459A1 (en) 2003-11-17
CA2484730A1 (fr) 2003-11-13
WO2003093795A3 (fr) 2004-10-21
AU2003234459A8 (en) 2003-11-17
EP1501917A2 (fr) 2005-02-02
JP2005524833A (ja) 2005-08-18

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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STAA Information on the status of an ep patent application or granted ep patent

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RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 33/574 20060101ALI20060221BHEP

Ipc: G01N 33/543 20060101ALI20060221BHEP

Ipc: G01N 21/64 20060101ALI20060221BHEP

Ipc: C12M 1/34 20060101AFI20041104BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20060303

18W Application withdrawn

Effective date: 20060327