EP1494674A4 - Carboximide derivatives as useful uro-selective alpha-1a adrenoceptor blockers - Google Patents

Carboximide derivatives as useful uro-selective alpha-1a adrenoceptor blockers

Info

Publication number
EP1494674A4
EP1494674A4 EP02720343A EP02720343A EP1494674A4 EP 1494674 A4 EP1494674 A4 EP 1494674A4 EP 02720343 A EP02720343 A EP 02720343A EP 02720343 A EP02720343 A EP 02720343A EP 1494674 A4 EP1494674 A4 EP 1494674A4
Authority
EP
European Patent Office
Prior art keywords
uro
useful
selective alpha
adrenoceptor blockers
carboximide derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02720343A
Other languages
German (de)
French (fr)
Other versions
EP1494674A1 (en
Inventor
Mohammad Salman
Gyan Chand Yadav
Somesh Sharma
Gobind Singh Kapkoti
Anita Chugh
Jang Bahadur Gupta
Nitya Anand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ranbaxy Laboratories Ltd
Original Assignee
Ranbaxy Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Publication of EP1494674A1 publication Critical patent/EP1494674A1/en
Publication of EP1494674A4 publication Critical patent/EP1494674A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
EP02720343A 2002-04-08 2002-04-08 Carboximide derivatives as useful uro-selective alpha-1a adrenoceptor blockers Withdrawn EP1494674A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB2002/001108 WO2003084541A1 (en) 2002-04-08 2002-04-08 Carboximide derivatives as useful uro-selective alpha-1a adrenoceptor blockers

Publications (2)

Publication Number Publication Date
EP1494674A1 EP1494674A1 (en) 2005-01-12
EP1494674A4 true EP1494674A4 (en) 2006-04-12

Family

ID=28686909

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02720343A Withdrawn EP1494674A4 (en) 2002-04-08 2002-04-08 Carboximide derivatives as useful uro-selective alpha-1a adrenoceptor blockers

Country Status (8)

Country Link
EP (1) EP1494674A4 (en)
JP (1) JP2005532282A (en)
CN (1) CN1627946A (en)
AU (1) AU2002251409A1 (en)
BR (1) BR0215686A (en)
EA (1) EA200401335A1 (en)
MX (1) MXPA04009821A (en)
WO (1) WO2003084541A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003259391A1 (en) * 2003-08-25 2005-03-10 Ranbaxy Laboratories Limited Metabolites of 1-{3-4`4-(2-methoxyphenyl) piperazin-1-yl!-propyl}-piperidine-2, 6-dione for use in the treatment of benign prostatic hyperplasia
AU2003278403A1 (en) * 2003-10-15 2005-05-05 Ranbaxy Laboratories Limited 1-alkylpiperazinyl-pyrrolidin-2, 5-dione derivatives as adrenergic receptor antagonist

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997037983A1 (en) * 1996-04-05 1997-10-16 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) α1-ADRENERGIC RECEPTOR ANTAGONISTS
WO1999006384A1 (en) * 1997-08-01 1999-02-11 Recordati S.A., Chemical And Pharmaceutical Company 1-(n-phenylaminoalkyl)-piperazine derivatives substituted at position 2 of the phenyl ring
US6083950A (en) * 1997-11-13 2000-07-04 Ranbaxy Laboratories Limited 1-(4-arylpiperazin-1-yl)-ω-[n-(α,ω-dicarboximido)]-alka nes useful as uro-selective α1-adrenoceptor blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2781220B1 (en) * 1998-07-17 2000-10-13 Lafon Labor SUBSTITUTED BETA PIPERAZINONES

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997037983A1 (en) * 1996-04-05 1997-10-16 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) α1-ADRENERGIC RECEPTOR ANTAGONISTS
WO1999006384A1 (en) * 1997-08-01 1999-02-11 Recordati S.A., Chemical And Pharmaceutical Company 1-(n-phenylaminoalkyl)-piperazine derivatives substituted at position 2 of the phenyl ring
US6083950A (en) * 1997-11-13 2000-07-04 Ranbaxy Laboratories Limited 1-(4-arylpiperazin-1-yl)-ω-[n-(α,ω-dicarboximido)]-alka nes useful as uro-selective α1-adrenoceptor blockers

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO03084541A1 *

Also Published As

Publication number Publication date
WO2003084541A1 (en) 2003-10-16
CN1627946A (en) 2005-06-15
JP2005532282A (en) 2005-10-27
BR0215686A (en) 2005-02-22
MXPA04009821A (en) 2004-12-13
EA200401335A1 (en) 2006-02-24
AU2002251409A1 (en) 2003-10-20
EP1494674A1 (en) 2005-01-12

Similar Documents

Publication Publication Date Title
AP2005003343A0 (en) Substituted pyrrolo-pyrazole derivatives as kinaseinhibitors
IL165810A0 (en) Novel benzimidazole derivatives
IL166366A0 (en) Aryl substituted benzimidazoles and their use as sodium channel blockers
AP1850A (en) Spiroindolineplperidine derivatives
HK1088326A1 (en) Piperidine-benzenesulfonamide derivatives
PL374718A1 (en) Azolidinone-vinyl fused-benzene derivatives
IL166624A0 (en) Taxane derivatives
IL204829A0 (en) Aniline derivatives
IL185604A0 (en) Pyrrolo-triazine aniline derivatives
DE50307780D1 (en) OPTOELECTRONIC COMPONENT
GB0217900D0 (en) Optoelectronic devices
GB0317665D0 (en) Qinazoline derivatives
PL376475A1 (en) N-substituted-2-oxodihydropyridine derivatives
IS7874A (en) Imidazoquinoline derivatives as adenosine A3 receptors
IL165058A0 (en) Optical article
HK1097957A1 (en) Pin photodetector
EP1501509A4 (en) Aryl-link-aryl substituted thiazolidine-dione and oxazolidine-dione as sodium channel blockers
GB0213504D0 (en) Optoelectronic devices
SG120090A1 (en) Indicating light
EP1495000A4 (en) Alpha, omega-dicarboximide derivatives as useful uro-selective a1a adrenoceptor blockers
PL1682129T3 (en) N-thiazol-2-yl-benzamide derivatives
AU2003298839A1 (en) Benzimidazoles and analogs thereof as antivirals
SI1706373T1 (en) Amidoacetonitrile derivatives
AU3472600A (en) Polyazanaphthalenone derivatives useful as alpha 1a adrenoceptor antagonists
GB0307661D0 (en) Optoelectronic devices

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20041108

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1075392

Country of ref document: HK

A4 Supplementary search report drawn up and despatched

Effective date: 20060301

17Q First examination report despatched

Effective date: 20061002

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: RANBAXY LABORATORIES LIMITED

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20081101

REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1075392

Country of ref document: HK