EP1429747A4 - Preparation de noyau comprenant un hydrochlorure de pioglitazone et un biguanide - Google Patents

Preparation de noyau comprenant un hydrochlorure de pioglitazone et un biguanide

Info

Publication number
EP1429747A4
EP1429747A4 EP01952548A EP01952548A EP1429747A4 EP 1429747 A4 EP1429747 A4 EP 1429747A4 EP 01952548 A EP01952548 A EP 01952548A EP 01952548 A EP01952548 A EP 01952548A EP 1429747 A4 EP1429747 A4 EP 1429747A4
Authority
EP
European Patent Office
Prior art keywords
biguanide
pioglitazone hydrochloride
core formulation
formulation
core
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01952548A
Other languages
German (de)
English (en)
Other versions
EP1429747A1 (fr
Inventor
Akwete L Adjei
Yaping Zhu
Anthony J Cutie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kos Life Sciences Inc
Original Assignee
Kos Life Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kos Life Sciences Inc filed Critical Kos Life Sciences Inc
Publication of EP1429747A1 publication Critical patent/EP1429747A1/fr
Publication of EP1429747A4 publication Critical patent/EP1429747A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
EP01952548A 2001-07-10 2001-07-10 Preparation de noyau comprenant un hydrochlorure de pioglitazone et un biguanide Withdrawn EP1429747A4 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2001/021615 WO2003005995A1 (fr) 2001-07-10 2001-07-10 Preparation de noyau comprenant un hydrochlorure de pioglitazone et un biguanide

Publications (2)

Publication Number Publication Date
EP1429747A1 EP1429747A1 (fr) 2004-06-23
EP1429747A4 true EP1429747A4 (fr) 2005-01-05

Family

ID=21742689

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01952548A Withdrawn EP1429747A4 (fr) 2001-07-10 2001-07-10 Preparation de noyau comprenant un hydrochlorure de pioglitazone et un biguanide

Country Status (6)

Country Link
EP (1) EP1429747A4 (fr)
JP (1) JP2004536843A (fr)
AU (1) AU2001273289B2 (fr)
CA (1) CA2453775A1 (fr)
MX (1) MXPA04000180A (fr)
WO (1) WO2003005995A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004536841A (ja) * 2001-07-10 2004-12-09 エアロファーム テクノロジー インコーポレイテッド コア製剤
CA2492722A1 (fr) * 2002-07-11 2004-01-22 Takeda Pharmaceutical Company Limited Procede de production d'une preparation recouverte
AU2004208606B2 (en) 2003-01-29 2009-09-24 Takeda Pharmaceutical Company Limited Process for producing coated preparation
US20060159776A1 (en) * 2003-07-19 2006-07-20 Warren Ward Compositions comprising components coated with a liquid impermeable but gas permeable layer, use thereof for treating cutaneous and other exocrine gland diseases
GB0316940D0 (en) * 2003-07-19 2003-08-27 Ward Warren Treatment of skin and other medical conditions
WO2005021542A2 (fr) * 2003-08-28 2005-03-10 Ranbaxy Laboratories Limited Procede pour la preparation de pioglitazone
WO2006076191A2 (fr) * 2005-01-10 2006-07-20 Elc Management Llc Revetement de surface discontinue pour particules
MXPA05014092A (es) * 2005-12-20 2007-06-20 Leopoldo De Jesus Espinosa Abdala Composiciones farmaceuticas que comprenden sustancias derivadas de la tiazolidinedionas combinadas con una biguanida para su uso en diabetes mellitus tipo 2.

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997041842A1 (fr) * 1996-05-09 1997-11-13 The Trustees Of The University Of Pennsylvania Particules creuses contenant du calcium et du phosphate du type mineral et destinees a un tissu osseux___________________________
WO1999003477A1 (fr) * 1997-07-18 1999-01-28 Smithkline Beecham P.L.C. Traitement du diabete avec du thiazolidinedione, un secretagogue d'insuline et du biguanide
US6011049A (en) * 1997-02-19 2000-01-04 Warner-Lambert Company Combinations for diabetes
WO2000044681A2 (fr) * 1999-02-01 2000-08-03 The Curators Of The University Of Missouri Procede de preparation de coques ou de gels a partir de particules de verre
WO2001082875A2 (fr) * 2000-05-01 2001-11-08 Aeropharm Technology, Inc. Formulation de noyau
WO2003005991A1 (fr) * 2001-07-10 2003-01-23 Aeropharm Technology Incorporated Formulation de noyau
WO2003005993A1 (fr) * 2000-05-01 2003-01-23 Aeropharm Technology Incorporated Formulation de noyau comprenant de la troglitazone et un biguanide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI238064B (en) * 1995-06-20 2005-08-21 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997041842A1 (fr) * 1996-05-09 1997-11-13 The Trustees Of The University Of Pennsylvania Particules creuses contenant du calcium et du phosphate du type mineral et destinees a un tissu osseux___________________________
US6011049A (en) * 1997-02-19 2000-01-04 Warner-Lambert Company Combinations for diabetes
WO1999003477A1 (fr) * 1997-07-18 1999-01-28 Smithkline Beecham P.L.C. Traitement du diabete avec du thiazolidinedione, un secretagogue d'insuline et du biguanide
WO2000044681A2 (fr) * 1999-02-01 2000-08-03 The Curators Of The University Of Missouri Procede de preparation de coques ou de gels a partir de particules de verre
WO2001082875A2 (fr) * 2000-05-01 2001-11-08 Aeropharm Technology, Inc. Formulation de noyau
WO2003005993A1 (fr) * 2000-05-01 2003-01-23 Aeropharm Technology Incorporated Formulation de noyau comprenant de la troglitazone et un biguanide
WO2003005991A1 (fr) * 2001-07-10 2003-01-23 Aeropharm Technology Incorporated Formulation de noyau

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO03005995A1 *

Also Published As

Publication number Publication date
EP1429747A1 (fr) 2004-06-23
AU2001273289B2 (en) 2004-10-07
CA2453775A1 (fr) 2003-01-23
MXPA04000180A (es) 2004-11-22
JP2004536843A (ja) 2004-12-09
WO2003005995A1 (fr) 2003-01-23

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Legal Events

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Effective date: 20040109

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AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

A4 Supplementary search report drawn up and despatched

Effective date: 20041122

RIC1 Information provided on ipc code assigned before grant

Ipc: 7A 61K 9/50 B

Ipc: 7A 61K 31/4439 B

Ipc: 7A 61K 31/155 B

Ipc: 7A 61K 9/16 A

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Effective date: 20050323

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20060131