EP1411966A4 - Verfahren zur behandlung sekundärer gewebedegeneration im zusammenhang mit schäden des zentralen nervensystems - Google Patents

Verfahren zur behandlung sekundärer gewebedegeneration im zusammenhang mit schäden des zentralen nervensystems

Info

Publication number
EP1411966A4
EP1411966A4 EP02746998A EP02746998A EP1411966A4 EP 1411966 A4 EP1411966 A4 EP 1411966A4 EP 02746998 A EP02746998 A EP 02746998A EP 02746998 A EP02746998 A EP 02746998A EP 1411966 A4 EP1411966 A4 EP 1411966A4
Authority
EP
European Patent Office
Prior art keywords
nervous system
central nervous
system injury
tissue degeneration
secondary tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02746998A
Other languages
English (en)
French (fr)
Other versions
EP1411966A2 (de
Inventor
Hans S Keirstead
Thomas E Lane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California filed Critical University of California
Publication of EP1411966A2 publication Critical patent/EP1411966A2/de
Publication of EP1411966A4 publication Critical patent/EP1411966A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
EP02746998A 2001-07-12 2002-07-12 Verfahren zur behandlung sekundärer gewebedegeneration im zusammenhang mit schäden des zentralen nervensystems Withdrawn EP1411966A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30502501P 2001-07-12 2001-07-12
US305025P 2001-07-12
PCT/US2002/022201 WO2003006045A2 (en) 2001-07-12 2002-07-12 Cxcl10 treatment of secondary tissue degeneration

Publications (2)

Publication Number Publication Date
EP1411966A2 EP1411966A2 (de) 2004-04-28
EP1411966A4 true EP1411966A4 (de) 2005-06-01

Family

ID=23178982

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02746998A Withdrawn EP1411966A4 (de) 2001-07-12 2002-07-12 Verfahren zur behandlung sekundärer gewebedegeneration im zusammenhang mit schäden des zentralen nervensystems

Country Status (5)

Country Link
EP (1) EP1411966A4 (de)
JP (2) JP2005501036A (de)
AU (1) AU2002316674B2 (de)
CA (1) CA2452544A1 (de)
WO (1) WO2003006045A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003006045A2 (en) * 2001-07-12 2003-01-23 The Regents Of The University Of California Cxcl10 treatment of secondary tissue degeneration
KR20130133302A (ko) 2003-12-10 2013-12-06 메다렉스, 인코포레이티드 Ｉｐ―１０ 항체 및 그의 용도
JP2010013355A (ja) * 2006-10-19 2010-01-21 Stelic Institute Of Regenerative Medicine 心筋障害抑制剤
CN101668774B (zh) 2007-02-28 2013-06-26 诺维莫尼公司 抗干扰素诱导蛋白-10的抗体及其使用方法
JP5963233B2 (ja) * 2011-12-07 2016-08-03 学校法人 聖マリアンナ医科大学 Ｈｔｌｖ−１関連脊髄症を治療または予防するための医薬および前記医薬を用いた抗体療法の治療効果の確認方法
US10556948B2 (en) 2015-11-30 2020-02-11 Bristol-Myers Squibb Company IP-10 antibodies and their uses
EP3471754A1 (de) 2016-06-20 2019-04-24 Kymab Limited Anti-pd-l1-antikörper

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998011218A1 (en) * 1996-09-10 1998-03-19 Theodor-Kocher Institute Cxcr3 chemokine receptor, antibodies, nucleic acids, and methods of use
WO2002098346A2 (en) * 2001-06-05 2002-12-12 Rappaport Family Institute For Research In The Medical Sciences Method and pharmaceutical composition for the treatment of multiple sclerosis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6407209B1 (en) * 1986-04-15 2002-06-18 Novartis Ag Interferon-induced human protein in pure form, monoclonal antibodies thereto and test kits containing these antibodies
US5728377A (en) * 1993-07-20 1998-03-17 Board Of Regents, The University Of Texas System Methods and compositions incorporating IP-10
US5994292A (en) * 1995-05-31 1999-11-30 The United States Of America As Represented By The Department Of Health And Human Services Interferon-inducible protein 10 is a potent inhibitor of angiogenesis
AU2001288286B2 (en) * 2000-08-18 2007-05-10 The Regents Of The University Of California Methods for treating demyelinating diseases
WO2003006045A2 (en) * 2001-07-12 2003-01-23 The Regents Of The University Of California Cxcl10 treatment of secondary tissue degeneration

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998011218A1 (en) * 1996-09-10 1998-03-19 Theodor-Kocher Institute Cxcr3 chemokine receptor, antibodies, nucleic acids, and methods of use
WO2002098346A2 (en) * 2001-06-05 2002-12-12 Rappaport Family Institute For Research In The Medical Sciences Method and pharmaceutical composition for the treatment of multiple sclerosis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GILLESPIE G ET AL: "Reducing the T cell response to central nervous system injury decreases posttraumatic degeneration", 2001, SOCIETY FOR NEUROSCIENCE ABSTRACTS, VOL. 27, NR. 2, PAGE(S) 2036, 31ST ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE; SAN DIEGO, CALIFORNIA, USA; NOVEMBER 10-15, 2001, ISSN: 0190-5295, XP001205706 *
MCTIGUE DANA M ET AL: "Selective chemokine mRNA accumulation in the rat spinal cord after contusion injury", JOURNAL OF NEUROSCIENCE RESEARCH, vol. 53, no. 3, 1 August 1998 (1998-08-01), pages 368 - 376, XP002322021, ISSN: 0360-4012 *
WOJCIK WALTER J ET AL: "Chronic intrathecal infusion of phosphorothioate or phosphodiester antisense oligonucleotides against cytokine responsive gene-2/IP-10 in experimental allergic encephalomyelitis of Lewis rat", JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 278, no. 1, 1996, pages 404 - 410, XP009045589, ISSN: 0022-3565 *

Also Published As

Publication number Publication date
AU2002316674B2 (en) 2007-09-13
JP2006008705A (ja) 2006-01-12
WO2003006045A3 (en) 2003-12-18
WO2003006045A2 (en) 2003-01-23
CA2452544A1 (en) 2003-01-23
JP2005501036A (ja) 2005-01-13
EP1411966A2 (de) 2004-04-28

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