EP1390057A4 - Anticorps se liant aux polypeptides antigeniques, acides nucleiques codant les antigenes, et methode d'utilisation - Google Patents
Anticorps se liant aux polypeptides antigeniques, acides nucleiques codant les antigenes, et methode d'utilisationInfo
- Publication number
- EP1390057A4 EP1390057A4 EP02763906A EP02763906A EP1390057A4 EP 1390057 A4 EP1390057 A4 EP 1390057A4 EP 02763906 A EP02763906 A EP 02763906A EP 02763906 A EP02763906 A EP 02763906A EP 1390057 A4 EP1390057 A4 EP 1390057A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- bind
- nucleic acids
- antigens
- acids encoding
- antigenic polypeptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 239000000427 antigen Substances 0.000 title 1
- 230000000890 antigenic effect Effects 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 239000012634 fragment Substances 0.000 abstract 2
- 238000003745 diagnosis Methods 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/0115—N-Acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (2.4.1.150)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Applications Claiming Priority (51)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28108601P | 2001-04-03 | 2001-04-03 | |
US281086P | 2001-04-03 | ||
US28190601P | 2001-04-05 | 2001-04-05 | |
US281906P | 2001-04-05 | ||
US28202001P | 2001-04-06 | 2001-04-06 | |
US282020P | 2001-04-06 | ||
US28293001P | 2001-04-10 | 2001-04-10 | |
US282930P | 2001-04-10 | ||
US28344401P | 2001-04-12 | 2001-04-12 | |
US28351201P | 2001-04-12 | 2001-04-12 | |
US283444P | 2001-04-12 | ||
US283512P | 2001-04-12 | ||
US28371001P | 2001-04-13 | 2001-04-13 | |
US28365701P | 2001-04-13 | 2001-04-13 | |
US28367801P | 2001-04-13 | 2001-04-13 | |
US283678P | 2001-04-13 | ||
US283657P | 2001-04-13 | ||
US283710P | 2001-04-13 | ||
US28423401P | 2001-04-17 | 2001-04-17 | |
US284234P | 2001-04-17 | ||
US28532501P | 2001-04-19 | 2001-04-19 | |
US285325P | 2001-04-19 | ||
US28538101P | 2001-04-20 | 2001-04-20 | |
US285381P | 2001-04-20 | ||
US28606801P | 2001-04-24 | 2001-04-24 | |
US286068P | 2001-04-24 | ||
US28629201P | 2001-04-25 | 2001-04-25 | |
US286292P | 2001-04-25 | ||
US29669201P | 2001-06-07 | 2001-06-07 | |
US296692P | 2001-06-07 | ||
US30088301P | 2001-06-26 | 2001-06-26 | |
US300883P | 2001-06-26 | ||
US31100301P | 2001-08-08 | 2001-08-08 | |
US311003P | 2001-08-08 | ||
US31197301P | 2001-08-13 | 2001-08-13 | |
US311973P | 2001-08-13 | ||
US31290101P | 2001-08-16 | 2001-08-16 | |
US312901P | 2001-08-16 | ||
US32228301P | 2001-09-14 | 2001-09-14 | |
US322283P | 2001-09-14 | ||
US32744801P | 2001-10-05 | 2001-10-05 | |
US327448P | 2001-10-05 | ||
US34573401P | 2001-12-31 | 2001-12-31 | |
US345734P | 2001-12-31 | ||
US34575502P | 2002-01-03 | 2002-01-03 | |
US345755P | 2002-01-03 | ||
US35439102P | 2002-02-04 | 2002-02-04 | |
US354391P | 2002-02-04 | ||
US10/114,153 US20030185815A1 (en) | 2001-04-03 | 2002-04-02 | Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use |
PCT/US2002/010366 WO2002081625A2 (fr) | 2001-04-03 | 2002-04-03 | Nouveaux anticorps se liant a des polypeptides antigeniques, acides nucleiques codant pour ces antigenes, et procedes d'utilisation de ceux-ci |
US114153P | 2008-11-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1390057A2 EP1390057A2 (fr) | 2004-02-25 |
EP1390057A4 true EP1390057A4 (fr) | 2005-10-12 |
Family
ID=28795516
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP02763906A Withdrawn EP1390057A4 (fr) | 2001-04-03 | 2002-04-03 | Anticorps se liant aux polypeptides antigeniques, acides nucleiques codant les antigenes, et methode d'utilisation |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1390057A4 (fr) |
JP (1) | JP2005507236A (fr) |
CA (1) | CA2442739A1 (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101512203B1 (ko) * | 2006-11-10 | 2015-04-15 | 가부시키가이샤 리부텍쿠 | in vivo 에서 항종양 활성을 갖는 항인간 Dlk-1 항체 |
EP2275537B1 (fr) | 2008-03-17 | 2014-12-24 | Livtech Inc. | Anticorps anti-humain spécifiques de dlk1 présentant une activité anti-tumorale in vivo |
EP3172228B1 (fr) * | 2014-07-25 | 2019-02-27 | Theravectys | Vecteurs lentiviraux por l'expression modulable d'un recepteur d'antigène chimerique |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000058473A2 (fr) * | 1999-03-31 | 2000-10-05 | Curagen Corporation | Acides nucleiques comprenant des phases de lecture ouverte codant des polypeptides; «orfx» |
WO2001083744A2 (fr) * | 2000-05-02 | 2001-11-08 | Merck Patent Gmbh | Nouvelle proteine echangeuse sodium-calcium |
-
2002
- 2002-04-03 CA CA002442739A patent/CA2442739A1/fr not_active Abandoned
- 2002-04-03 EP EP02763906A patent/EP1390057A4/fr not_active Withdrawn
- 2002-04-03 JP JP2002579989A patent/JP2005507236A/ja active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000058473A2 (fr) * | 1999-03-31 | 2000-10-05 | Curagen Corporation | Acides nucleiques comprenant des phases de lecture ouverte codant des polypeptides; «orfx» |
WO2001083744A2 (fr) * | 2000-05-02 | 2001-11-08 | Merck Patent Gmbh | Nouvelle proteine echangeuse sodium-calcium |
Non-Patent Citations (7)
Title |
---|
DATABASE EMBL [online] 20 November 1995 (1995-11-20), "Homo sapiens partial SCL8A3 gene for solute carrier family 8 (sodium/calcium exchanger), member 3 (SCL8A3), exon 2", XP002210607, retrieved from EBI accession no. EM_HUM:HSNCX22 Database accession no. HSNCX22 * |
DATABASE EMBL [online] 6 June 2001 (2001-06-06), "Homo sapiens mRNA for sodium/calcium exchanger SCL8A3, alternative splice form A (SCL8A3 gene)", XP002327581, retrieved from EBI accession no. EM_PRO:AJ304852 Database accession no. AJ304852 * |
DATABASE EMBL [online] 6 June 2001 (2001-06-06), "Homo sapiens mRNA for sodium/calcium exchanger, SCL8A3, alternative splice form B (SCL8A3 gene)", XP002222548, retrieved from EBI accession no. EM_PRO:HSA304853 Database accession no. HSA304853 * |
DATABASE SWISSPROT [online] 1 October 2000 (2000-10-01), "Sodium/calcium exchanger 2 precursor (Na+/Ca2+-exchange protein 2).", XP002327580, retrieved from EBI Database accession no. Q9UPR5 * |
EGGER M ET AL: "Regulatory function of Na-Ca exchange in the heart: milestones and outlook.", THE JOURNAL OF MEMBRANE BIOLOGY. 15 MAR 1999, vol. 168, no. 2, 15 March 1999 (1999-03-15), pages 107 - 130, XP002327588, ISSN: 0022-2631 * |
IWAMOTO TAKAHIRO ET AL: "Chimeric analysis of Na+/Ca2+ exchangers NCX1 and NCX3 reveals structural domains important for differential sensitivity to external Ni2+ or Li+", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 33, 13 August 1999 (1999-08-13), pages 23094 - 23102, XP002327579, ISSN: 0021-9258 * |
KRAEV A ET AL: "The organization of the human gene NCX1 encoding the sodium-calcium exchanger", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 37, no. 1, 1996, pages 105 - 112, XP002181613, ISSN: 0888-7543 * |
Also Published As
Publication number | Publication date |
---|---|
EP1390057A2 (fr) | 2004-02-25 |
CA2442739A1 (fr) | 2002-10-17 |
JP2005507236A (ja) | 2005-03-17 |
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Legal Events
Date | Code | Title | Description |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 20031031 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
AX | Request for extension of the european patent |
Extension state: AL LT LV MK RO SI |
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RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: MAZUR, ANN Inventor name: STONE, DAVID J. Inventor name: EDINGER, SHLOMIT R. Inventor name: MACDOUGALL, JOHN R. Inventor name: CATTERTON, ELINA Inventor name: PEYMAN, JOHN A. Inventor name: JU, JINGFANG Inventor name: HEYES, MELVYN P. Inventor name: TAUPIER, RAYMOND J., JR. Inventor name: MILLER, CHARLES, E. Inventor name: PATTURAJAN, MEERA Inventor name: MALYANKAR, URIEL M. Inventor name: SPYTEK, KIMBERLY, A. Inventor name: VERNET, CORINE, A., M. Inventor name: GANGOLLI, ESHA, A. Inventor name: TCHERNEV, VELIZAR, T. Inventor name: ZERHUSEN, BRYAN, D. Inventor name: LI, LI Inventor name: BOLDOG, FERENC, L. Inventor name: CASMAN, STACIE, J. Inventor name: GERLACH, VALERIE Inventor name: GUO, XIAOJIA Inventor name: SMITHSON, GLENNDA Inventor name: MEZES, PETER, S. Inventor name: RASTELLI, LUCA Inventor name: KEKUDA, RAMESH Inventor name: SHENOY, SURESH, G. Inventor name: PADIGARU, MURALIDHARA |
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RTI1 | Title (correction) |
Free format text: NOVEL ANTIBODIES THAT BIND TO ANTIGENIC POLYPEPTIDES, NUCLEIC ACIDS ENCODING THE ANTIGENS, AND METHOD OF USE |
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RTI1 | Title (correction) |
Free format text: NOVEL ANTIBODIES THAT BIND TO ANTIGENIC POLYPEPTIDES, NUCLEIC ACIDS ENCODING THE ANTIGENS, AND METHOD OF USE |
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7C 12N 15/12 B Ipc: 7C 07K 14/47 A |
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A4 | Supplementary search report drawn up and despatched |
Effective date: 20050824 |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN |
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18W | Application withdrawn |
Effective date: 20060217 |