EP1377287A4 - Proanthocyanidines destinees au traitement des amyloses et des maladies induites par alpha-synucleine - Google Patents
Proanthocyanidines destinees au traitement des amyloses et des maladies induites par alpha-synucleineInfo
- Publication number
- EP1377287A4 EP1377287A4 EP02719009A EP02719009A EP1377287A4 EP 1377287 A4 EP1377287 A4 EP 1377287A4 EP 02719009 A EP02719009 A EP 02719009A EP 02719009 A EP02719009 A EP 02719009A EP 1377287 A4 EP1377287 A4 EP 1377287A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- proanthocyanidins
- amyloid
- alpha
- treatment
- synuclein diseases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27686601P | 2001-03-15 | 2001-03-15 | |
US276866P | 2001-03-15 | ||
US09/938,987 US6607758B2 (en) | 1997-05-15 | 2001-08-24 | Methods for inhibiting and reducing amyloid fibril formation associated with Alzheimer's Disease and other amyloidoses |
US938987 | 2001-08-24 | ||
US10/053,625 US6929808B2 (en) | 2000-11-03 | 2001-11-02 | Methods of isolating amyloid-inhibiting compounds and use of compounds isolated from Uncaria tomentosa and related plants |
WOPCT/US05/01131 | 2001-11-02 | ||
US53625 | 2001-11-02 | ||
PCT/US2001/051131 WO2002042429A2 (fr) | 2000-11-03 | 2001-11-02 | Procedes d'isolement de composes inhibiteurs d'amyloide, et utilisation de composes utilises a partir d'uncaria tomentosa et de plantes parentes |
US33872101P | 2001-12-04 | 2001-12-04 | |
US338721P | 2001-12-04 | ||
US33896901P | 2001-12-10 | 2001-12-10 | |
US33903301P | 2001-12-10 | 2001-12-10 | |
US339033P | 2001-12-10 | ||
US338969P | 2001-12-10 | ||
PCT/US2002/004764 WO2002076381A2 (fr) | 2001-03-15 | 2002-02-15 | Proanthocyanidines destinees au traitement des amyloses et des maladies induites par alpha-synucleine |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1377287A2 EP1377287A2 (fr) | 2004-01-07 |
EP1377287A4 true EP1377287A4 (fr) | 2007-11-14 |
Family
ID=56290250
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP02719009A Withdrawn EP1377287A4 (fr) | 2001-03-15 | 2002-02-15 | Proanthocyanidines destinees au traitement des amyloses et des maladies induites par alpha-synucleine |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1377287A4 (fr) |
JP (1) | JP4380991B2 (fr) |
AU (1) | AU2002250117B2 (fr) |
CA (1) | CA2441099C (fr) |
NZ (1) | NZ528322A (fr) |
WO (1) | WO2002076381A2 (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070208087A1 (en) | 2001-11-02 | 2007-09-06 | Sanders Virginia J | Compounds, compositions and methods for the treatment of inflammatory diseases |
US7514107B2 (en) | 2002-03-21 | 2009-04-07 | Mars, Incorporated | Treatment of diseases involving defective gap junctional communication |
DK1511710T3 (en) * | 2002-05-31 | 2014-02-24 | Proteotech Inc | RELATIONSHIPS, PREPARATIONS AND METHODS FOR TREATING AMYLOID DISEASES AND SYNUCLEINOPATHES, SUCH AS ALZHEIMER'S DISEASE, TYPE 2-DIABETES AND PARKINSON'S DISEASE |
CA2499549C (fr) * | 2002-10-11 | 2012-01-24 | Proteotech, Inc. | Isolation, purification et synthese de procyanidine b2, et ses utilisations |
JP2006232670A (ja) * | 2003-05-20 | 2006-09-07 | Ajinomoto Co Inc | 神経障害用薬剤 |
WO2005082351A1 (fr) * | 2004-03-02 | 2005-09-09 | Eisai R & D Management Co., Ltd. | Agent thérapeutique pour un trouble neurodégénératif |
CA2645946C (fr) * | 2006-03-29 | 2014-04-01 | Wista Laboratories Ltd. | Inhibiteurs de l'agregation de proteines |
WO2009104556A1 (fr) * | 2008-02-19 | 2009-08-27 | 株式会社岐阜セラツク製造所 | Composition |
EP2291191A4 (fr) * | 2008-05-09 | 2014-01-22 | Sinai School Medicine | Procédés de prévention et de traitement de maladies neurodégénératives |
US20140179774A1 (en) * | 2012-12-26 | 2014-06-26 | Industrial Technology Research Institute | Methods for inhibition of shc-1/p66 to combat aging-related diseases |
WO2016181945A1 (fr) | 2015-05-11 | 2016-11-17 | 株式会社明治 | Composition pour faciliter la production du facteur neurotrophique dérivé du cerveau |
KR102441381B1 (ko) * | 2016-07-18 | 2022-09-07 | (주)아모레퍼시픽 | 3-O-갈로일-3,3',5,5',7-펜타하이드록시플라반(3-O-galloyl-3,3',5,5',7- pentahydroxyflavan)을 포함하는 인지 기능 개선용 조성물 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5922756A (en) * | 1998-02-14 | 1999-07-13 | Chan; Marion Man-Ying | Method of inhibiting nitric oxide synthase |
WO1999045797A1 (fr) * | 1998-03-12 | 1999-09-16 | Mars, Incorporated | Produits contenant du ou des polyphenols et de l'arginine-l favorisant la production d'oxyde nitrique |
WO2000030666A1 (fr) * | 1998-11-24 | 2000-06-02 | University Of Washington | Composition et procedes pour inhiber la formation de depots de substances amyloides dans le cerveau |
WO2001049307A1 (fr) * | 1999-12-30 | 2001-07-12 | Proteotech, Inc. | Catechines et extrait de the vert destines au traitement de l'amyloidose dans la maladie d'alzheimer et d'autres amyloidoses |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4698360B1 (en) * | 1985-04-09 | 1997-11-04 | D Investigations Pharmacologiq | Plant extract with a proanthocyanidins content as therapeutic agent having radical scavenger effect and use thereof |
ES2285772T3 (es) * | 1997-05-15 | 2007-11-16 | University Of Washington | Composicion y metodos para tratar la enfermedad de alzheimer y otras amiloidosis. |
AU3886200A (en) * | 1999-03-15 | 2000-10-16 | Proteotech, Inc. | Methods of treating alzheimer's disease and other amyloidoses using hypericum perforatum and derivatives thereof |
-
2002
- 2002-02-15 NZ NZ528322A patent/NZ528322A/en not_active IP Right Cessation
- 2002-02-15 AU AU2002250117A patent/AU2002250117B2/en not_active Ceased
- 2002-02-15 CA CA2441099A patent/CA2441099C/fr not_active Expired - Fee Related
- 2002-02-15 EP EP02719009A patent/EP1377287A4/fr not_active Withdrawn
- 2002-02-15 JP JP2002574897A patent/JP4380991B2/ja not_active Expired - Fee Related
- 2002-02-15 WO PCT/US2002/004764 patent/WO2002076381A2/fr active IP Right Grant
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5922756A (en) * | 1998-02-14 | 1999-07-13 | Chan; Marion Man-Ying | Method of inhibiting nitric oxide synthase |
WO1999045797A1 (fr) * | 1998-03-12 | 1999-09-16 | Mars, Incorporated | Produits contenant du ou des polyphenols et de l'arginine-l favorisant la production d'oxyde nitrique |
WO2000030666A1 (fr) * | 1998-11-24 | 2000-06-02 | University Of Washington | Composition et procedes pour inhiber la formation de depots de substances amyloides dans le cerveau |
WO2001049307A1 (fr) * | 1999-12-30 | 2001-07-12 | Proteotech, Inc. | Catechines et extrait de the vert destines au traitement de l'amyloidose dans la maladie d'alzheimer et d'autres amyloidoses |
Also Published As
Publication number | Publication date |
---|---|
EP1377287A2 (fr) | 2004-01-07 |
WO2002076381A3 (fr) | 2002-11-21 |
AU2002250117B2 (en) | 2007-11-29 |
CA2441099A1 (fr) | 2002-10-03 |
CA2441099C (fr) | 2011-04-19 |
JP4380991B2 (ja) | 2009-12-09 |
AU2002250117B8 (en) | 2002-10-08 |
NZ528322A (en) | 2005-03-24 |
JP2005505497A (ja) | 2005-02-24 |
WO2002076381A2 (fr) | 2002-10-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20030924 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
AX | Request for extension of the european patent |
Extension state: AL LT LV MK RO SI |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: NGUYEN, BETH, P. Inventor name: CHOI, PAULA, Y. Inventor name: CASTILLO, GERALDO, M. Inventor name: SNOW, ALAN, D. |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 3/10 20060101ALI20070717BHEP Ipc: A61P 25/28 20060101ALI20070717BHEP Ipc: A61P 25/16 20060101ALI20070717BHEP Ipc: A61K 31/353 20060101ALI20070717BHEP Ipc: A61K 31/352 20060101ALI20070717BHEP Ipc: A61K 31/35 20060101AFI20070717BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20071016 |
|
17Q | First examination report despatched |
Effective date: 20090618 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20120925 |